2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone

2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone is a lipid of Polyketides (PK) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 137 references associated with 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone

MeSH term MeSH ID Detail
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Total 1

NCBI Entrez Crosslinks

All references with 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone

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Authors Title Published Journal PubMed Link
Wei X et al. 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone, a potent Nrf2/ARE pathway inhibitor, reverses drug resistance by decreasing glutathione synthesis and drug efflux in BEL-7402/5-FU cells. 2018 Food Chem. Toxicol. pmid:29626576
de Oliveira Cabral C et al. Gastroprotective potential of methanolic extract and dimethyl cardamonin from Campomanesia reitziana fruits in mice. 2017 Naunyn Schmiedebergs Arch. Pharmacol. pmid:28365824
Choi JW et al. DMC (2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone) improves glucose tolerance as a potent AMPK activator. 2016 Metab. Clin. Exp. pmid:26975545
Yu WG et al. Dual role of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone in inhibiting high-mobility group box 1 secretion and blocking its pro-inflammatory activity in hepatic inflammation. 2014 J. Agric. Food Chem. pmid:25400111
Lu Y et al. Protective effects of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone against hydrogen peroxide-induced oxidative stress in hepatic L02 cell. 2014 Arch. Pharm. Res. pmid:24469602
Hu YC et al. 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone promoted glucose uptake and imposed a paradoxical effect on adipocyte differentiation in 3T3-L1 cells. 2014 J. Agric. Food Chem. pmid:24517891
Hu YC et al. 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone protects the impaired insulin secretion induced by glucotoxicity in pancreatic β-cells. 2014 J. Agric. Food Chem. pmid:24437980
Wei H et al. Chalcone derivatives from the fern Cyclosorus parasiticus and their anti-proliferative activity. 2013 Food Chem. Toxicol. pmid:23891701
Martínez A et al. Protective effect against oxygen reactive species and skin fibroblast stimulation of Couroupita guianensis leaf extracts. 2012 Nat. Prod. Res. pmid:21432721
Luo Y and Lu Y 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits apoptosis of MIN6 cells via improving mitochondrial function. 2012 Pharmazie pmid:23016455