2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone

2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone is a lipid of Polyketides (PK) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 137 references associated with 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone

MeSH term MeSH ID Detail
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Total 1

NCBI Entrez Crosslinks

All references with 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone

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Authors Title Published Journal PubMed Link
pmid:
Lu Y et al. Protective effects of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone against hydrogen peroxide-induced oxidative stress in hepatic L02 cell. 2014 Arch. Pharm. Res. pmid:24469602
Ye CL et al. In vivo antitumor activity by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone in a solid human carcinoma xenograft model. 2005 Cancer Chemother. Pharmacol. pmid:15806415
Wei X et al. 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone, a potent Nrf2/ARE pathway inhibitor, reverses drug resistance by decreasing glutathione synthesis and drug efflux in BEL-7402/5-FU cells. 2018 Food Chem. Toxicol. pmid:29626576
Wei H et al. Chalcone derivatives from the fern Cyclosorus parasiticus and their anti-proliferative activity. 2013 Food Chem. Toxicol. pmid:23891701
Kim YJ et al. Dimethyl cardamonin inhibits lipopolysaccharide-induced inflammatory factors through blocking NF-kappaB p65 activation. 2010 Int. Immunopharmacol. pmid:20609401
Qian F et al. In vitro and in vivo reversal of cancer cell multidrug resistance by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone. 2005 J Chemother pmid:16038525
Yu WG et al. Hepatoprotective effects of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone on CCl4-induced acute liver injury in mice. 2011 J. Agric. Food Chem. pmid:22098609
Hu YC et al. In vitro investigation of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone for glycemic control. 2012 J. Agric. Food Chem. pmid:23013379
Hu YC et al. 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone promoted glucose uptake and imposed a paradoxical effect on adipocyte differentiation in 3T3-L1 cells. 2014 J. Agric. Food Chem. pmid:24517891