MeSH term | MeSH ID | Detail |
---|---|---|
Chemical and Drug Induced Liver Injury | D056486 | 39 associated lipids |
Total
1
2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone is a lipid of Polyketides (PK) class.
We collected disease MeSH terms mapped to the references associated with 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone
MeSH term | MeSH ID | Detail |
---|---|---|
Chemical and Drug Induced Liver Injury | D056486 | 39 associated lipids |
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Wei X et al. | 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone, a potent Nrf2/ARE pathway inhibitor, reverses drug resistance by decreasing glutathione synthesis and drug efflux in BEL-7402/5-FU cells. | 2018 | Food Chem. Toxicol. | pmid:29626576 |
de Oliveira Cabral C et al. | Gastroprotective potential of methanolic extract and dimethyl cardamonin from Campomanesia reitziana fruits in mice. | 2017 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:28365824 |
Choi JW et al. | DMC (2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone) improves glucose tolerance as a potent AMPK activator. | 2016 | Metab. Clin. Exp. | pmid:26975545 |
Yu WG et al. | Dual role of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone in inhibiting high-mobility group box 1 secretion and blocking its pro-inflammatory activity in hepatic inflammation. | 2014 | J. Agric. Food Chem. | pmid:25400111 |
Lu Y et al. | Protective effects of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone against hydrogen peroxide-induced oxidative stress in hepatic L02 cell. | 2014 | Arch. Pharm. Res. | pmid:24469602 |
Hu YC et al. | 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone promoted glucose uptake and imposed a paradoxical effect on adipocyte differentiation in 3T3-L1 cells. | 2014 | J. Agric. Food Chem. | pmid:24517891 |
Hu YC et al. | 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone protects the impaired insulin secretion induced by glucotoxicity in pancreatic β-cells. | 2014 | J. Agric. Food Chem. | pmid:24437980 |
Wei H et al. | Chalcone derivatives from the fern Cyclosorus parasiticus and their anti-proliferative activity. | 2013 | Food Chem. Toxicol. | pmid:23891701 |
MartÃnez A et al. | Protective effect against oxygen reactive species and skin fibroblast stimulation of Couroupita guianensis leaf extracts. | 2012 | Nat. Prod. Res. | pmid:21432721 |
Huang HY et al. | Multidrug resistance reversal effect of DMC derived from buds of Cleistocalyx operculatus in human hepatocellular tumor xenograft model. | 2012 | J. Sci. Food Agric. | pmid:21780130 |
Hu YC et al. | In vitro investigation of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone for glycemic control. | 2012 | J. Agric. Food Chem. | pmid:23013379 |
Luo Y and Lu Y | 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits apoptosis of MIN6 cells via improving mitochondrial function. | 2012 | Pharmazie | pmid:23016455 |
Ko H et al. | Induction of autophagy by dimethyl cardamonin is associated with proliferative arrest in human colorectal carcinoma HCT116 and LOVO cells. | 2011 | J. Cell. Biochem. | pmid:21538483 |
Su MY et al. | Protective effects of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone to PC12 cells against cytotoxicity induced by hydrogen peroxide. | 2011 | J. Agric. Food Chem. | pmid:21186823 |
Huang HY et al. | Reversal effect of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone on multi-drug resistance in resistant human hepatocellular carcinoma cell line BEL-7402/5-FU. | 2011 | Phytomedicine | pmid:21596545 |
Yu WG et al. | Hepatoprotective effects of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone on CCl4-induced acute liver injury in mice. | 2011 | J. Agric. Food Chem. | pmid:22098609 |
Kim YJ et al. | Dimethyl cardamonin inhibits lipopolysaccharide-induced inflammatory factors through blocking NF-kappaB p65 activation. | 2010 | Int. Immunopharmacol. | pmid:20609401 |
Ye CL et al. | In vivo antitumor activity by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone in a solid human carcinoma xenograft model. | 2005 | Cancer Chemother. Pharmacol. | pmid:15806415 |
Qian F et al. | In vitro and in vivo reversal of cancer cell multidrug resistance by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone. | 2005 | J Chemother | pmid:16038525 |
Salem MM and Werbovetz KA | Antiprotozoal compounds from Psorothamnus polydenius. | 2005 | J. Nat. Prod. | pmid:15679330 |