Fronhofer V et al. |
Role of PKC isoforms in the Fc(gamma)R-mediated inhibition of LPS-stimulated IL-12 secretion by macrophages. |
2006 |
J. Leukoc. Biol. |
pmid:16330529
|
Nakajima T et al. |
Regulation of radiation-induced protein kinase Cdelta activation in radiation-induced apoptosis differs between radiosensitive and radioresistant mouse thymic lymphoma cell lines. |
2006 |
Mutat. Res. |
pmid:16337250
|
Hanrott K et al. |
6-hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta. |
2006 |
J. Biol. Chem. |
pmid:16361258
|
Tapia JA et al. |
Rottlerin inhibits stimulated enzymatic secretion and several intracellular signaling transduction pathways in pancreatic acinar cells by a non-PKC-delta-dependent mechanism. |
2006 |
Biochim. Biophys. Acta |
pmid:16364465
|
Ringshausen I et al. |
Mechanisms of apoptosis-induction by rottlerin: therapeutic implications for B-CLL. |
2006 |
Leukemia |
pmid:16437144
|
Zatta AJ et al. |
Infarct-sparing effect of myocardial postconditioning is dependent on protein kinase C signalling. |
2006 |
Cardiovasc. Res. |
pmid:16443207
|
Zhu M et al. |
Involvement of mitogen-activated protein kinases and protein kinase C in regulation of antioxidant response element activity in human keratinocytes. |
2006 |
Cancer Lett. |
pmid:16455194
|
Rushworth SA et al. |
Role of protein kinase C delta in curcumin-induced antioxidant response element-mediated gene expression in human monocytes. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:16460683
|
Barman SA and Marrero MB |
Mechanism of endothelin-1 activation of MAP kinases in neonatal pulmonary vascular smooth muscle. |
2005 Nov-Dec |
Lung |
pmid:16465602
|
Ikewaki N et al. |
Regulation of CD93 cell surface expression by protein kinase C isoenzymes. |
2006 |
Microbiol. Immunol. |
pmid:16490927
|
SedmÃková M et al. |
Effect of protein kinase C inhibitors on porcine oocyte activation. |
2006 |
J. Exp. Zoolog. Part A Comp. Exp. Biol. |
pmid:16493646
|
Jang IS et al. |
Lysophosphatidic acid-induced changes in cAMP profiles in young and senescent human fibroblasts as a clue to the ageing process. |
2006 |
Mech. Ageing Dev. |
pmid:16516270
|
Waki K et al. |
Involvement of protein kinase Cdelta in the activation of NADPH oxidase and the phagocytosis of neutrophils. |
2006 |
Free Radic. Res. |
pmid:16517500
|
Hsu PC et al. |
Increasing ornithine decarboxylase activity is another way of prolactin preventing methotrexate-induced apoptosis: crosstalk between ODC and BCL-2. |
2006 |
Apoptosis |
pmid:16520895
|
Shukla A et al. |
Transcriptional up-regulation of MMP12 and MMP13 by asbestos occurs via a PKCdelta-dependent pathway in murine lung. |
2006 |
FASEB J. |
pmid:16571779
|
Ahn BK et al. |
Rottlerin, a specific inhibitor of protein kinase C-delta, impedes barrier repair response by increasing intracellular free calcium. |
2006 |
J. Invest. Dermatol. |
pmid:16575394
|
Cronshaw DG et al. |
Evidence that phospholipase-C-dependent, calcium-independent mechanisms are required for directional migration of T-lymphocytes in response to the CCR4 ligands CCL17 and CCL22. |
2006 |
J. Leukoc. Biol. |
pmid:16614259
|
Zhu S et al. |
Effect of PKC isozyme inhibition on forskolin-induced activation of BKCa channels in rat pulmonary arterial smooth muscle. |
2006 Mar-Apr |
Lung |
pmid:16622778
|
Zou Y et al. |
Contact inhibition causes strong downregulation of expression of MICA in human fibroblasts and decreased NK cell killing. |
2006 |
Hum. Immunol. |
pmid:16698440
|
Nobe K et al. |
High-glucose-altered endothelial cell function involves both disruption of cell-to-cell connection and enhancement of force development. |
2006 |
J. Pharmacol. Exp. Ther. |
pmid:16699065
|
Im YJ et al. |
Multiple actions of lysophosphatidylcholine in human Jurkat T cells. |
2006 |
Acta Pharmacol. Sin. |
pmid:16723088
|
Lee CF et al. |
Involvement of protein kinase C delta in the alteration of mitochondrial mass in human cells under oxidative stress. |
2006 |
Free Radic. Biol. Med. |
pmid:16785027
|
Pakozdi A et al. |
Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis. |
2006 |
Arthritis Res. Ther. |
pmid:16872482
|
Thomas R and Kim MH |
Targeting the hypoxia inducible factor pathway with mitochondrial uncouplers. |
2007 |
Mol. Cell. Biochem. |
pmid:16924414
|
Zeng H et al. |
Mallotoxin is a novel human ether-a-go-go-related gene (hERG) potassium channel activator. |
2006 |
J. Pharmacol. Exp. Ther. |
pmid:16928897
|
Pula G et al. |
PKCdelta regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation. |
2006 |
Blood |
pmid:16940418
|
Zhou Y et al. |
Different roles of protein kinase C-betaI and -delta in the regulation of adipocyte differentiation. |
2006 |
Int. J. Biochem. Cell Biol. |
pmid:16950644
|
Shoenfelt JL and Fenton MJ |
TLR2- and TLR4-dependent activation of STAT1 serine phosphorylation in murine macrophages is protein kinase C-delta-independent. |
2006 |
J. Endotoxin Res. |
pmid:16953975
|
Jane EP et al. |
Coadministration of sorafenib with rottlerin potently inhibits cell proliferation and migration in human malignant glioma cells. |
2006 |
J. Pharmacol. Exp. Ther. |
pmid:16959960
|
Sarkis PT et al. |
STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-alpha. |
2006 |
J. Immunol. |
pmid:16982890
|
Takahashi A et al. |
Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence. |
2006 |
Nat. Cell Biol. |
pmid:17028578
|
Ceni E et al. |
Acetaldehyde inhibits PPARgamma via H2O2-mediated c-Abl activation in human hepatic stellate cells. |
2006 |
Gastroenterology |
pmid:17030193
|
Grybko MJ et al. |
Protein kinase C activity is required for cytotoxic T cell lytic granule exocytosis, but the theta isoform does not play a preferential role. |
2007 |
J. Leukoc. Biol. |
pmid:17077164
|
Chantara W et al. |
Acrylonitrile-induced extracellular signal-regulated kinase (ERK) activation via protein kinase C (PKC) in SK-N-SH neuroblastoma cells. |
|
J Appl Toxicol |
pmid:17080406
|
Choi EY et al. |
Involvement of protein kinase Cdelta in iron chelator-induced IL-8 production in human intestinal epithelial cells. |
2007 |
Life Sci. |
pmid:17097691
|
Kurosu T et al. |
Rottlerin synergistically enhances imatinib-induced apoptosis of BCR/ABL-expressing cells through its mitochondrial uncoupling effect independent of protein kinase C-delta. |
2007 |
Oncogene |
pmid:17130834
|
Shemon AN et al. |
Rottlerin inhibits P2X(7) receptor-stimulated phospholipase D activity in chronic lymphocytic leukaemia B-lymphocytes. |
2007 |
Immunol. Cell Biol. |
pmid:17130901
|
Wu SN et al. |
Potent stimulation of large-conductance Ca2+-activated K+ channels by rottlerin, an inhibitor of protein kinase C-delta, in pituitary tumor (GH3) cells and in cortical neuronal (HCN-1A) cells. |
2007 |
J. Cell. Physiol. |
pmid:17133362
|
Mishra R et al. |
TGF-beta-regulated collagen type I accumulation: role of Src-based signals. |
2007 |
Am. J. Physiol., Cell Physiol. |
pmid:17135298
|
Springael C et al. |
Rottlerin inhibits human T cell responses. |
2007 |
Biochem. Pharmacol. |
pmid:17141738
|
Shoichet BK |
Interpreting steep dose-response curves in early inhibitor discovery. |
2006 |
J. Med. Chem. |
pmid:17149857
|
Hassan HA et al. |
Regulation of anion exchanger Slc26a6 by protein kinase C. |
2007 |
Am. J. Physiol., Cell Physiol. |
pmid:17151144
|
Burkhart BA et al. |
Osmotic stress-dependent repression is mediated by histone H3 phosphorylation and chromatin structure. |
2007 |
J. Biol. Chem. |
pmid:17158874
|
Scott DW and Loo G |
Curcumin-induced GADD153 upregulation: modulation by glutathione. |
2007 |
J. Cell. Biochem. |
pmid:17171638
|
Gäreskog M and Wentzel P |
N-Acetylcysteine and alpha-cyano-4-hydroxycinnamic acid alter protein kinase C (PKC)-delta and PKC-zeta and diminish dysmorphogenesis in rat embryos cultured with high glucose in vitro. |
2007 |
J. Endocrinol. |
pmid:17210758
|
Di Baldassarre A et al. |
Protein kinase Calpha is differentially activated during neonatal and adult erythropoiesis and favors expression of a reporter gene under the control of the (A)gamma globin-promoter in cellular models of hemoglobin switching. |
2007 |
J. Cell. Biochem. |
pmid:17212360
|
Sun L et al. |
Microarray-based kinase inhibition assay by gold nanoparticle probes. |
2007 |
Anal. Chem. |
pmid:17222050
|
Chwae YJ et al. |
Activation-induced upregulation of inhibitory killer Ig-like receptors is regulated by protein kinase C. |
2007 Apr-May |
Immunol. Cell Biol. |
pmid:17228322
|
Chen ZF et al. |
[The effect of PKC-delta inhibitor Rottlerin on human colon cancer cell line SW1116 and its mechanism]. |
2006 |
Zhonghua Zhong Liu Za Zhi |
pmid:17236547
|
Lu R et al. |
Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases DNA methylation in colon cancer cells. |
2007 |
J. Biol. Chem. |
pmid:17307743
|
Fan Y et al. |
[Phosphorylation of PKCdelta participates in the toxicity of 6-hydroxydopamine on dopaminergic neuroblastoma cell]. |
2006 |
Zhonghua Yi Xue Za Zhi |
pmid:17313780
|
Kwon MJ et al. |
Role of PKCdelta in IFN-gamma-inducible CIITA gene expression. |
2007 |
Mol. Immunol. |
pmid:17346795
|
Park YS et al. |
Acrolein induces cyclooxygenase-2 and prostaglandin production in human umbilical vein endothelial cells: roles of p38 MAP kinase. |
2007 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:17363696
|
Bull ND et al. |
Protein kinase C-mediated modulation of glutamate transporter activity in rat retina. |
2007 |
Curr. Eye Res. |
pmid:17364745
|
Akar U et al. |
Tissue transglutaminase inhibits autophagy in pancreatic cancer cells. |
2007 |
Mol. Cancer Res. |
pmid:17374730
|
Guo B et al. |
Cutting Edge: B cell receptor (BCR) cross-talk: the IL-4-induced alternate pathway for BCR signaling operates in parallel with the classical pathway, is sensitive to Rottlerin, and depends on Lyn. |
2007 |
J. Immunol. |
pmid:17404251
|
Kim YH et al. |
Expression of cyclin D3 through Sp1 sites by histone deacetylase inhibitors is mediated with protein kinase C-delta (PKC-delta) signal pathway. |
2007 |
J. Cell. Biochem. |
pmid:17407153
|
Majewski M et al. |
Protein kinase C delta stimulates antigen presentation by Class II MHC in murine dendritic cells. |
2007 |
Int. Immunol. |
pmid:17446207
|
Ozpolat B et al. |
PKC delta and tissue transglutaminase are novel inhibitors of autophagy in pancreatic cancer cells. |
2007 Sep-Oct |
Autophagy |
pmid:17507797
|
Miura T et al. |
Delta-opioid receptor activation before ischemia reduces gap junction permeability in ischemic myocardium by PKC-epsilon-mediated phosphorylation of connexin 43. |
2007 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:17513490
|
Nakatake M et al. |
STAT3 and PKC differentially regulate telomerase activity during megakaryocytic differentiation of K562 cells. |
2007 |
Cell Cycle |
pmid:17525530
|
Pugazhenthi S et al. |
Regulation of heme oxygenase-1 expression by demethoxy curcuminoids through Nrf2 by a PI3-kinase/Akt-mediated pathway in mouse beta-cells. |
2007 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:17535857
|
Zhang D et al. |
Neuroprotective effect of protein kinase C delta inhibitor rottlerin in cell culture and animal models of Parkinson's disease. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17565007
|
Kamiya K et al. |
Protein kinase C delta activated adhesion regulates vascular smooth muscle cell migration. |
2007 |
J. Surg. Res. |
pmid:17574042
|
Löber K et al. |
STI571 (Glivec) affects histamine release and intracellular pH after alkalinisation in HMC-1560, 816. |
2008 |
J. Cell. Biochem. |
pmid:17615556
|
Kudirka JC et al. |
P2Y nucleotide receptor signaling through MAPK/ERK is regulated by extracellular matrix: involvement of beta3 integrins. |
2007 |
J. Cell. Physiol. |
pmid:17620283
|
Wang Y et al. |
Advanced glycation end products elicit externalization of phosphatidylserine in a subpopulation of platelets via 5-HT2A/2C receptors. |
2007 |
Am. J. Physiol., Cell Physiol. |
pmid:17625040
|
Ahn BH et al. |
Up-regulation of cyclooxygenase-2 by cobalt chloride-induced hypoxia is mediated by phospholipase D isozymes in human astroglioma cells. |
2007 |
Biochim. Biophys. Acta |
pmid:17640750
|
Kim BC et al. |
The anti-inflammatory activity of Phellinus linteus (Berk. & M.A. Curt.) is mediated through the PKCdelta/Nrf2/ARE signaling to up-regulation of heme oxygenase-1. |
2007 |
J Ethnopharmacol |
pmid:17644290
|
Kim BH et al. |
Distinct inhibitory mechanisms of isoquercitrin gallate and its aglycone on zymosan-induced peroxynitrite production in macrophages. |
2007 Nov-Dec |
Nitric Oxide |
pmid:17651994
|
Miller RL et al. |
Cytotoxicity of paraquat in microglial cells: Involvement of PKCdelta- and ERK1/2-dependent NADPH oxidase. |
2007 |
Brain Res. |
pmid:17662968
|
Wang Y et al. |
Differential effects of dialysis and ultrafiltrate from individuals with CKD, with or without diabetes, on platelet phosphatidylserine externalization. |
2008 |
Am. J. Physiol. Renal Physiol. |
pmid:17670899
|
Zhao Y et al. |
Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin. |
2007 |
Cell. Signal. |
pmid:17689924
|
Soltoff SP |
Rottlerin: an inappropriate and ineffective inhibitor of PKCdelta. |
2007 |
Trends Pharmacol. Sci. |
pmid:17692392
|
Brutkiewicz RR et al. |
Protein kinase C delta is a critical regulator of CD1d-mediated antigen presentation. |
2007 |
Eur. J. Immunol. |
pmid:17705133
|
Bierhals K et al. |
The epsilon-isoform of PKC mediates the hypertonic activation of cation channels in confluent monolayers of rat hepatocytes. |
2007 |
Cell. Physiol. Biochem. |
pmid:17762167
|
Bain J et al. |
The selectivity of protein kinase inhibitors: a further update. |
2007 |
Biochem. J. |
pmid:17850214
|
Klinger JR et al. |
Rottlerin causes pulmonary edema in vivo: a possible role for PKCdelta. |
2007 |
J. Appl. Physiol. |
pmid:17901241
|
Kim YH et al. |
Protein kinase C delta regulates anti-apoptotic alphaB-crystallin in the retina of type 2 diabetes. |
2007 |
Neurobiol. Dis. |
pmid:17904375
|
Xu SZ |
Rottlerin induces calcium influx and protein degradation in cultured lenses independent of effects on protein kinase C delta. |
2007 |
Basic Clin. Pharmacol. Toxicol. |
pmid:17927688
|
Martin L |
The replicon initiation burst released by reoxygenation of hypoxic T24 cells is accompanied by changes of MCM2 and Cdc7. |
2007 |
J. Biochem. Mol. Biol. |
pmid:17927916
|
Moschella PC et al. |
Regulation of mTOR and S6K1 activation by the nPKC isoforms, PKCepsilon and PKCdelta, in adult cardiac muscle cells. |
2007 |
J. Mol. Cell. Cardiol. |
pmid:17976640
|
Marengo B et al. |
Mechanisms of BSO (L-buthionine-S,R-sulfoximine)-induced cytotoxic effects in neuroblastoma. |
2008 |
Free Radic. Biol. Med. |
pmid:17991446
|
Zhang H and Forman HJ |
Acrolein induces heme oxygenase-1 through PKC-delta and PI3K in human bronchial epithelial cells. |
2008 |
Am. J. Respir. Cell Mol. Biol. |
pmid:18048804
|
Park JA et al. |
Protein kinase C delta regulates airway mucin secretion via phosphorylation of MARCKS protein. |
2007 |
Am. J. Pathol. |
pmid:18055557
|
McNally AK et al. |
Foreign body-type multinucleated giant cell formation requires protein kinase C beta, delta, and zeta. |
2008 |
Exp. Mol. Pathol. |
pmid:18067888
|
Shivshankar P et al. |
Rottlerin inhibits chlamydial intracellular growth and blocks chlamydial acquisition of sphingolipids from host cells. |
2008 |
Appl. Environ. Microbiol. |
pmid:18083882
|
Krutzik PO et al. |
High-content single-cell drug screening with phosphospecific flow cytometry. |
2008 |
Nat. Chem. Biol. |
pmid:18157122
|
Ramnath RD et al. |
Role of PKC-delta on substance P-induced chemokine synthesis in pancreatic acinar cells. |
2008 |
Am. J. Physiol., Cell Physiol. |
pmid:18160487
|
Sud N et al. |
Protein kinase Cdelta regulates endothelial nitric oxide synthase expression via Akt activation and nitric oxide generation. |
2008 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:18192589
|
Olson ER et al. |
Angiotensin II-induced extracellular signal-regulated kinase 1/2 activation is mediated by protein kinase Cdelta and intracellular calcium in adult rat cardiac fibroblasts. |
2008 |
Hypertension |
pmid:18195168
|
McEneaney V et al. |
Aldosterone regulates rapid trafficking of epithelial sodium channel subunits in renal cortical collecting duct cells via protein kinase D activation. |
2008 |
Mol. Endocrinol. |
pmid:18202152
|
Feng BY et al. |
Small-molecule aggregates inhibit amyloid polymerization. |
2008 |
Nat. Chem. Biol. |
pmid:18223646
|
Torricelli C et al. |
Rottlerin inhibits the nuclear factor kappaB/cyclin-D1 cascade in MCF-7 breast cancer cells. |
2008 |
Life Sci. |
pmid:18261747
|
Schonhoff CM et al. |
Protein kinase Cdelta mediates cyclic adenosine monophosphate-stimulated translocation of sodium taurocholate cotransporting polypeptide and multidrug resistant associated protein 2 in rat hepatocytes. |
2008 |
Hepatology |
pmid:18273864
|
Rishton GM |
Aggregator compounds confound amyloid fibrillization assay. |
2008 |
Nat. Chem. Biol. |
pmid:18277973
|
Park S et al. |
Chlorpromazine attenuates pancreatic beta-cell function and mass through IRS2 degradation, while exercise partially reverses the attenuation. |
2008 |
J. Psychopharmacol. (Oxford) |
pmid:18308779
|
Carraway RE et al. |
Protein kinase C inhibitors alter neurotensin receptor binding and function in prostate cancer PC3 cells. |
2008 |
Regul. Pept. |
pmid:18313772
|
Liu N et al. |
Erbin-regulated sensitivity of MCF-7 breast cancer cells to TRAIL via ErbB2/AKT/NF-kappaB pathway. |
2008 |
J. Biochem. |
pmid:18316330
|
Itoh T et al. |
Inhibitory effect of xanthones isolated from the pericarp of Garcinia mangostana L. on rat basophilic leukemia RBL-2H3 cell degranulation. |
2008 |
Bioorg. Med. Chem. |
pmid:18328716
|