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Nuclear factor of activated T cells 2 transactivation in mast cells: a novel isoform-specific transactivation domain confers unique FcepsilonRI responsiveness. |
2003 |
J. Biol. Chem. |
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Allyl alcohol activation of protein kinase C delta leads to cytotoxicity of rat hepatocytes. |
2003 |
Chem. Res. Toxicol. |
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Distinct isoforms of protein kinase C are involved in human eosinophil functions induced by platelet-activating factor. |
2003 |
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Protein kinase C-delta is commonly expressed in multiple myeloma cells and its downregulation by rottlerin causes apoptosis. |
2003 |
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Fatty acid and phorbol ester-mediated interference of mitogenic signaling via novel protein kinase C isoforms in pancreatic beta-cells (INS-1). |
2003 |
J. Mol. Endocrinol. |
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Attenuation of canine cerebral vasospasm after subarachnoid hemorrhage by protein kinase C inhibitors despite augmented phosphorylation of myosin light chain. |
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Activation of protein kinase C delta by IFN-gamma. |
2003 |
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Role of protein kinase C in geranylgeranylacetone-induced expression of heat-shock protein 72 and cardioprotection in the rat heart. |
2003 |
J. Mol. Cell. Cardiol. |
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Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: relevance to oxidative stress and dopaminergic degeneration. |
2003 |
Neuroscience |
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Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE). |
2003 |
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Rottlerin, an inhibitor of protein kinase Cdelta (PKCdelta), inhibits astrocytic glutamate transport activity and reduces GLAST immunoreactivity by a mechanism that appears to be PKCdelta-independent. |
2003 |
J. Neurochem. |
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Effect of detergent on "promiscuous" inhibitors. |
2003 |
J. Med. Chem. |
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A generic time-resolved fluorescence assay for serine/threonine kinase activity: application to Cdc7/Dbf4. |
2003 |
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Okadaic acid induces sustained activation of NFkappaB and degradation of the nuclear IkappaBalpha in human neutrophils. |
2003 |
Arch. Biochem. Biophys. |
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Role of PKC-delta activity in glutathione-depleted neuroblastoma cells. |
2003 |
Free Radic. Biol. Med. |
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Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria independent of protein kinase C. |
2003 |
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Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation. |
2003 |
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Protein kinase Calpha (PKCalpha) acts upstream of PKCtheta to activate IkappaB kinase and NF-kappaB in T lymphocytes. |
2003 |
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The c-Jun N-terminal kinase 1 activity is differentially regulated by specific mechanisms during apoptosis. |
2003 |
J. Biol. Chem. |
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Induction of cIAP-2 in human colon cancer cells through PKC delta/NF-kappa B. |
2003 |
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Induction of apoptosis by Se-MSC in U937 human leukemia cells through release of cytochrome c and activation of caspases and PKC-delta: mutual regulation between caspases and PKC-delta via a positive feedback mechanism. |
2003 |
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A novel role of protein kinase C-delta in cell signaling triggered by glutathione depletion. |
2003 |
Biochem. Pharmacol. |
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Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel. |
2004 |
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IL-4-dependent CD86 expression requires JAK/STAT6 activation and is negatively regulated by PKCdelta. |
2004 |
Cell. Signal. |
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Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR-induced Fas ligand expression. |
2003 |
Int. Immunol. |
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Localization of VEGFR-2 and PLD2 in endothelial caveolae is involved in VEGF-induced phosphorylation of MEK and ERK. |
2004 |
Am. J. Physiol. Heart Circ. Physiol. |
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Ceramide-induced apoptosis by translocation, phosphorylation, and activation of protein kinase Cdelta in the Golgi complex. |
2004 |
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Epidermal growth factor induces fibroblast contractility and motility via a protein kinase C delta-dependent pathway. |
2004 |
J. Biol. Chem. |
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Induction of hyaluronic acid synthase 2 (HAS2) in human vascular smooth muscle cells by vasodilatory prostaglandins. |
2004 |
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Evidence that protein kinase Cdelta is not required for palmitate-induced cytotoxicity in BRIN-BD11 beta-cells. |
2004 |
J. Mol. Endocrinol. |
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Expression of adhesion molecules by sphingosine 1-phosphate and histamine in endothelial cells. |
2004 |
Eur. J. Pharmacol. |
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PKC-epsilon regulation of extracellular signal-regulated kinase: a potential role in phenylephrine-induced cardiocyte growth. |
2004 |
Am. J. Physiol. Heart Circ. Physiol. |
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Laminin 5 deposition regulates keratinocyte polarization and persistent migration. |
2004 |
J. Cell. Sci. |
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Isoform-selectivity of PKC inhibitors acting at the regulatory and catalytic domain of mammalian PKC-alpha, -betaI, -delta, -eta and -zeta. |
2003 |
J Enzyme Inhib Med Chem |
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Down-regulation of Bcl-2 is associated with cisplatin resistance in human small cell lung cancer H69 cells. |
2004 |
Mol. Cancer Ther. |
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B cell receptor-induced cAMP-response element-binding protein activation in B lymphocytes requires novel protein kinase Cdelta. |
2004 |
J. Biol. Chem. |
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Selective activation of protein kinase C delta in human neutrophils following ischemia reperfusion of skeletal muscle. |
2004 |
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Epidermal growth factor induces fibronectin expression in human dermal fibroblasts via protein kinase C delta signaling pathway. |
2004 |
J. Invest. Dermatol. |
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Involvement of MAP-kinase, PI3-kinase and EGF-receptor in the stimulatory effect of Neurotensin on DNA synthesis in PC3 cells. |
2004 |
Regul. Pept. |
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Rottlerin inhibits multiple steps involved in insulin-induced glucose uptake in 3T3-L1 adipocytes. |
2004 |
Biochem. Pharmacol. |
pmid:15183122
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Li C et al. |
Regulation of CCK-induced amylase release by PKC-delta in rat pancreatic acinar cells. |
2004 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:15217780
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Shin SY et al. |
Transcriptional and post-transcriptional regulation of the PKC delta gene by etoposide in L1210 murine leukemia cells: implication of PKC delta autoregulation. |
2004 |
J. Mol. Biol. |
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Kang HS et al. |
Receptor activator of nuclear factor-kappaB is induced by a rottlerin-sensitive and p38 MAP kinase-dependent pathway during monocyte differentiation. |
2004 |
Mol. Cells |
pmid:15232218
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Chintalgattu V and Katwa LC |
Role of protein kinase Cdelta in endothelin-induced type I collagen expression in cardiac myofibroblasts isolated from the site of myocardial infarction. |
2004 |
J. Pharmacol. Exp. Ther. |
pmid:15240825
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Inhibition of Ca2+-dependent PKC isoforms unmasks ERK-dependent hypertrophic growth evoked by phenylephrine in adult ventricular cardiomyocytes. |
2004 |
Cardiovasc. Res. |
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Cummings R et al. |
Protein kinase Cdelta mediates lysophosphatidic acid-induced NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells. |
2004 |
J. Biol. Chem. |
pmid:15280372
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Wheaton K and Riabowol K |
Protein kinase C delta blocks immediate-early gene expression in senescent cells by inactivating serum response factor. |
2004 |
Mol. Cell. Biol. |
pmid:15282327
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Role of protein kinase C delta in reactivation of Kaposi's sarcoma-associated herpesvirus. |
2004 |
J. Virol. |
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Lladó A et al. |
Protein kinaseCdelta-calmodulin crosstalk regulates epidermal growth factor receptor exit from early endosomes. |
2004 |
Mol. Biol. Cell |
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