| MeSH term | MeSH ID | Detail |
|---|---|---|
| Parkinson Disease | D010300 | 53 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
| Hypertrophy | D006984 | 16 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Leukemia-Lymphoma, Adult T-Cell | D015459 | 25 associated lipids |
| Renal Insufficiency, Chronic | D051436 | 9 associated lipids |
| Hyperhomocysteinemia | D020138 | 6 associated lipids |
| Chlamydia Infections | D002690 | 7 associated lipids |
| MERRF Syndrome | D017243 | 1 associated lipids |
rottlerin
Rottlerin is a lipid of Polyketides (PK) class. Rottlerin is associated with abnormalities such as PARAGANGLIOMAS 2, Hyperostosis, Diffuse Idiopathic Skeletal, Virus Diseases, Perisylvian syndrome and Autoimmune disease (systemic) NOS. The involved functions are known as Apoptosis, Regulation, Signal Transduction, inhibitors and Proteasome Inhibitors [MoA]. Rottlerin often locates in Clone, Membrane, Body tissue, Plasma membrane and soluble. The associated genes with Rottlerin are XIAP gene, GAPDH gene, ICAM1 gene, P4HTM gene and TNFSF10 gene. The related lipids are Promega, Fatty Acids, Sphingolipids, Lipopolysaccharides and Saponin. The related experimental models are Mouse Model, Xenograft Model and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of rottlerin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with rottlerin?
rottlerin is suspected in Infection, Morphologically altered structure, Ischemia, Pulmonary Edema, Asthma, Cardiovascular Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- J. Biol. Chem. (5)
- Am. J. Physiol. Heart Circ. Physiol. (3)
- Am. J. Physiol. Lung Cell Mol. Physiol. (3)
- Others (19)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with rottlerin
PubChem Associated disorders and diseases
What pathways are associated with rottlerin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with rottlerin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Biol. Chem. (9)
- J. Pharmacol. Exp. Ther. (4)
- Am. J. Physiol. Lung Cell Mol. Physiol. (3)
- Others (42)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with rottlerin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with rottlerin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with rottlerin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with rottlerin?
Cancer Model
Cancer Model are used in the study 'Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family.' (Ohno I et al., 2010) and Cancer Model are used in the study 'Rottlerin induces Wnt co-receptor LRP6 degradation and suppresses both Wnt/β-catenin and mTORC1 signaling in prostate and breast cancer cells.' (Lu W et al., 2014).
Mouse Model
Mouse Model are used in the study 'Neuroprotective effect of protein kinase C delta inhibitor rottlerin in cell culture and animal models of Parkinson's disease.' (Zhang D et al., 2007).
Xenograft Model
Xenograft Model are used in the study 'Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family.' (Ohno I et al., 2010).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with rottlerin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Leonarduzzi G et al. | Oxidation as a crucial reaction for cholesterol to induce tissue degeneration: CD36 overexpression in human promonocytic cells treated with a biologically relevant oxysterol mixture. | 2008 | Aging Cell | pmid:18331615 |
| Kim S et al. | Role of protein kinase Cdelta in paraquat-induced glial cell death. | 2008 | J. Neurosci. Res. | pmid:18335519 |
| Fang Q et al. | PKCdelta mediates thrombin-augmented fibroblast-mediated collagen gel contraction. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18342628 |
| Hsu HY et al. | Heme oxygenase-1 mediates the anti-inflammatory effect of Curcumin within LPS-stimulated human monocytes. | 2008 | J. Cell. Physiol. | pmid:18357586 |
| Basu A et al. | Down-regulation of caspase-2 by rottlerin via protein kinase C-delta-independent pathway. | 2008 | Cancer Res. | pmid:18413747 |
| Goon Goh F et al. | G-protein-dependent and -independent pathways regulate proteinase-activated receptor-2 mediated p65 NFkappaB serine 536 phosphorylation in human keratinocytes. | 2008 | Cell. Signal. | pmid:18424071 |
| Song KS et al. | Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: the protective role of autophagy in apoptosis. | 2008 | Autophagy | pmid:18424913 |
| Kim YH et al. | Protein kinase C-delta mediates neuronal apoptosis in the retinas of diabetic rats via the Akt signaling pathway. | 2008 | Diabetes | pmid:18443201 |
| Byun HS et al. | Prevention of TNF-induced necrotic cell death by rottlerin through a Nox1 NADPH oxidase. | 2008 | Exp. Mol. Med. | pmid:18446057 |
| Sakai H et al. | Probable involvement of epsilon-isoform of protein kinase C in rat bronchial smooth muscle contraction induced by acetylcholine. | 2008 | J Smooth Muscle Res | pmid:18480594 |
| Lee JS et al. | House dust mite, Dermatophagoides pteronissinus increases expression of MCP-1, IL-6, and IL-8 in human monocytic THP-1 cells. | 2008 | Cytokine | pmid:18490175 |
| Alonso E et al. | The effect of rottlerin in calcium regulation in HMC-1(560) cells is mediated by a PKC-delta independent effect. | 2008 | J. Cell. Biochem. | pmid:18500723 |
| Lee MC et al. | Novel PKC signaling is required for LPS-induced soluble Flt-1 expression in macrophages. | 2008 | J. Leukoc. Biol. | pmid:18511573 |
| Ross R et al. | Hypothalamic protein kinase C regulates glucose production. | 2008 | Diabetes | pmid:18511848 |
| Lin CW et al. | Quercetin inhibition of tumor invasion via suppressing PKC delta/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells. | 2008 | Carcinogenesis | pmid:18628248 |
| Longpre JM and Loo G | Protection of human colon epithelial cells against deoxycholate by rottlerin. | 2008 | Apoptosis | pmid:18661240 |
| Dreixler JC et al. | Protein kinase C subtypes and retinal ischemic preconditioning. | 2008 | Exp. Eye Res. | pmid:18722601 |
| Kaur K et al. | Possible mechanism of rottlerin induced modulation of ischemia reperfusion injury in isolated rat hearts. | 2008 | Biol. Pharm. Bull. | pmid:18758070 |
| Kojima K et al. | Rottlerin activates AMPK possibly through LKB1 in vascular cells and tissues. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18789895 |
| Lim JH et al. | Rottlerin induces pro-apoptotic endoplasmic reticulum stress through the protein kinase C-delta-independent pathway in human colon cancer cells. | 2008 | Apoptosis | pmid:18807195 |
| BACKHOUSE T and McGOOKIN A | Rottlerin; the synthesis of tetrahydrorottlerin and of tetrahydroallorottlerin and the reversibility of the rottlerone change. | 1948 | J Chem Soc | pmid:18906365 |
| Lim JH et al. | Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC delta-independent mechanism in human malignant tumor cells. | 2009 | Carcinogenesis | pmid:19037087 |
| Jang BC | Induction of COX-2 in human airway cells by manganese: role of PI3K/PKB, p38 MAPK, PKCs, Src, and glutathione depletion. | 2009 | Toxicol In Vitro | pmid:19084589 |
| Mok SA et al. | A retrograde apoptotic signal originating in NGF-deprived distal axons of rat sympathetic neurons in compartmented cultures. | 2009 | Cell Res. | pmid:19188931 |
| Doller A et al. | Angiotensin II induces renal plasminogen activator inhibitor-1 and cyclooxygenase-2 expression post-transcriptionally via activation of the mRNA-stabilizing factor human-antigen R. | 2009 | Am. J. Pathol. | pmid:19246637 |
| Raghu H et al. | Kaposi's sarcoma-associated herpesvirus utilizes an actin polymerization-dependent macropinocytic pathway to enter human dermal microvascular endothelial and human umbilical vein endothelial cells. | 2009 | J. Virol. | pmid:19279100 |
| Coan KE et al. | Promiscuous aggregate-based inhibitors promote enzyme unfolding. | 2009 | J. Med. Chem. | pmid:19281222 |
| Suzuki T and Hara H | Quercetin enhances intestinal barrier function through the assembly of zonula [corrected] occludens-2, occludin, and claudin-1 and the expression of claudin-4 in Caco-2 cells. | 2009 | J. Nutr. | pmid:19297429 |
| Choi YA et al. | Integrin signaling and cell spreading alterations by rottlerin treatment of chick limb bud mesenchymal cells. | 2009 | Biochimie | pmid:19306958 |
| Lima F et al. | Connexin43 potentiates osteoblast responsiveness to fibroblast growth factor 2 via a protein kinase C-delta/Runx2-dependent mechanism. | 2009 | Mol. Biol. Cell | pmid:19339281 |
| Kurosu T et al. | Sorafenib induces apoptosis specifically in cells expressing BCR/ABL by inhibiting its kinase activity to activate the intrinsic mitochondrial pathway. | 2009 | Cancer Res. | pmid:19366808 |
| Satoh K et al. | Phosphorylation of myristoylated alanine-rich C kinase substrate is involved in the cAMP-dependent amylase release in parotid acinar cells. | 2009 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:19372103 |
| Matsuoka H et al. | Tamoxifen inhibits tumor cell invasion and metastasis in mouse melanoma through suppression of PKC/MEK/ERK and PKC/PI3K/Akt pathways. | 2009 | Exp. Cell Res. | pmid:19393235 |
| Di Rosa M et al. | Prolactin induces chitotriosidase expression in human macrophages through PTK, PI3-K, and MAPK pathways. | 2009 | J. Cell. Biochem. | pmid:19415692 |
| Park SK et al. | Kalopanaxsaponin A inhibits PMA-induced invasion by reducing matrix metalloproteinase-9 via PI3K/Akt- and PKCdelta-mediated signaling in MCF-7 human breast cancer cells. | 2009 | Carcinogenesis | pmid:19420016 |
| Liu CY et al. | Activation of PKCdelta and ERK1/2 in the sensitivity to UV-induced apoptosis of human cells harboring 4977 bp deletion of mitochondrial DNA. | 2009 | Biochim. Biophys. Acta | pmid:19477272 |
| Valacchi G et al. | Rottlerin: a multifaced regulator of keratinocyte cell cycle. | 2009 | Exp. Dermatol. | pmid:19492998 |
| Nguyen KT et al. | Rottlerin inhibits (Na+, K+)-ATPase activity in brain tissue and alters D-aspartate dependent redistribution of glutamate transporter GLAST in cultured astrocytes. | 2009 | Neurochem. Res. | pmid:19495968 |
| Hufnagel H et al. | Fluid phase endocytosis contributes to transfection of DNA by PEI-25. | 2009 | Mol. Ther. | pmid:19532143 |
| Chintalgattu V and Katwa LC | Role of protein kinase C-delta in angiotensin II induced cardiac fibrosis. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19540196 |
| Fordjour AK and Harrington EO | PKCdelta influences p190 phosphorylation and activity: events independent of PKCdelta-mediated regulation of endothelial cell stress fiber and focal adhesion formation and barrier function. | 2009 | Biochim. Biophys. Acta | pmid:19632305 |
| Fan Y et al. | Rottlerin protected dopaminergic cell line from cytotoxicity of 6-hydroxydopamine by inhibiting PKCdelta phosphorylation. | 2009 | Neurosci Bull | pmid:19633700 |
| Esper RM and Loeb JA | Neurotrophins induce neuregulin release through protein kinase Cdelta activation. | 2009 | J. Biol. Chem. | pmid:19648576 |
| Zhao M et al. | Protein kinase Cdelta stimulates proteasome-dependent degradation of C/EBPalpha during apoptosis induction of leukemic cells. | 2009 | PLoS ONE | pmid:19662097 |
| Kang JH et al. | Plasma protein kinase C (PKC)alpha as a biomarker for the diagnosis of cancers. | 2009 | Carcinogenesis | pmid:19710177 |
| Gao FH et al. | Protein kinase C-delta mediates down-regulation of heterogeneous nuclear ribonucleoprotein K protein: involvement in apoptosis induction. | 2009 | Exp. Cell Res. | pmid:19747914 |
| Thrower EC et al. | Protein kinase C delta-mediated processes in cholecystokinin-8-stimulated pancreatic acini. | 2009 | Pancreas | pmid:19752773 |
| Ohno I et al. | Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family. | 2010 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:19762431 |
| Balgi AD et al. | Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling. | 2009 | PLoS ONE | pmid:19771169 |
| McEneaney V et al. | Protein kinase D stabilizes aldosterone-induced ERK1/2 MAP kinase activation in M1 renal cortical collecting duct cells to promote cell proliferation. | 2010 | J. Steroid Biochem. Mol. Biol. | pmid:19804826 |
| Park EJ et al. | Rottlerin induces heme oxygenase-1 (HO-1) up-regulation through reactive oxygen species (ROS) dependent and PKC delta-independent pathway in human colon cancer HT29 cells. | 2010 | Biochimie | pmid:19833168 |
| Kato K et al. | Caspase-mediated protein kinase C-delta cleavage is necessary for apoptosis of vascular smooth muscle cells. | 2009 | Am. J. Physiol. Heart Circ. Physiol. | pmid:19837952 |
| Rohilla A et al. | Possible involvement of PKC-delta in the abrogated cardioprotective potential of ischemic preconditioning in hyperhomocysteinemic rat hearts. | 2010 | Biomed. Pharmacother. | pmid:19914792 |
| Rohilla A and Balakumar P | The infarct size-limiting effect of ischemic postconditioning (IPOC) is suppressed in isolated hyperhomocysteinemic (Hhcy) rat hearts: the reasonable role of PKC-delta. | 2009 | Biomed. Pharmacother. | pmid:19914793 |
| Leppänen T et al. | Inhibition of protein kinase Cdelta reduces tristetraprolin expression by destabilizing its mRNA in activated macrophages. | 2010 | Eur. J. Pharmacol. | pmid:19925787 |
| Bhatt KH et al. | Protein kinase Cdelta and protein tyrosine kinase regulate peptidoglycan-induced nuclear factor-kappaB activation and inducible nitric oxide synthase expression in mouse peritoneal macrophages in vitro. | 2010 | Mol. Immunol. | pmid:19931912 |
| Shen SM et al. | Downregulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells. | 2010 | Carcinogenesis | pmid:20015864 |
| Liu J et al. | The effect of PKC activation and inhibition on osteogenic differentiation of human mesenchymal stem cells. | 2010 | J Tissue Eng Regen Med | pmid:20033927 |
| Kim KM et al. | Puerarin suppresses AGEs-induced inflammation in mouse mesangial cells: a possible pathway through the induction of heme oxygenase-1 expression. | 2010 | Toxicol. Appl. Pharmacol. | pmid:20060010 |
| Arisaka M et al. | Involvement of protein kinase Cdelta in induction of apoptosis by cationic liposomes in macrophage-like RAW264.7 cells. | 2010 | FEBS Lett. | pmid:20122929 |
| Wallerstedt E et al. | Protein kinase C-delta is involved in the inflammatory effect of IL-6 in mouse adipose cells. | 2010 | Diabetologia | pmid:20151299 |
| Maioli E et al. | Rottlerin inhibits ROS formation and prevents NFkappaB activation in MCF-7 and HT-29 cells. | 2009 | J. Biomed. Biotechnol. | pmid:20168983 |
| Mertens-Walker I et al. | Gonadotropin-induced ovarian cancer cell migration and proliferation require extracellular signal-regulated kinase 1/2 activation regulated by calcium and protein kinase C{delta}. | 2010 | Endocr. Relat. Cancer | pmid:20215102 |
| Sugiya H et al. | Role of protein kinase C-delta in isoproterenol-induced amylase release in rat parotid acinar cells. | 2009 | J. Med. Invest. | pmid:20224227 |
| Lin CJ et al. | Rottlerin inhibits migration of follicular thyroid carcinoma cells by PKCdelta-independent destabilization of the focal adhesion complex. | 2010 | J. Cell. Biochem. | pmid:20225271 |
| Li X et al. | PKC-delta promotes renal tubular cell apoptosis associated with proteinuria. | 2010 | J. Am. Soc. Nephrol. | pmid:20395372 |
| Ko NY et al. | Interleukin-32α production is regulated by MyD88-dependent and independent pathways in IL-1β-stimulated human alveolar epithelial cells. | 2011 Jan-Feb | Immunobiology | pmid:20430472 |
| Behl M et al. | Lead-induced accumulation of beta-amyloid in the choroid plexus: role of low density lipoprotein receptor protein-1 and protein kinase C. | 2010 | Neurotoxicology | pmid:20488202 |
| Maioli E and Valacchi G | Rottlerin: bases for a possible usage in psoriasis. | 2010 | Curr. Drug Metab. | pmid:20540694 |
| Hwang YP et al. | 3-Caffeoyl, 4-dihydrocaffeoylquinic acid from Salicornia herbacea inhibits tumor cell invasion by regulating protein kinase C-delta-dependent matrix metalloproteinase-9 expression. | 2010 | Toxicol. Lett. | pmid:20599481 |
| Lanaspa MA et al. | The expression of aquaporin-1 in the medulla of the kidney is dependent on the transcription factor associated with hypertonicity, TonEBP. | 2010 | J. Biol. Chem. | pmid:20639513 |
| Das J et al. | Protective role of taurine against arsenic-induced mitochondria-dependent hepatic apoptosis via the inhibition of PKCdelta-JNK pathway. | 2010 | PLoS ONE | pmid:20830294 |
| Lee HG and Yang JH | PKC-δ mediates TCDD-induced apoptosis of chondrocyte in ROS-dependent manner. | 2010 | Chemosphere | pmid:20846705 |
| Matta C et al. | PKCdelta is a positive regulator of chondrogenesis in chicken high density micromass cell cultures. | 2011 | Biochimie | pmid:20850497 |
| Wang Y et al. | Protein kinase C regulates urea permeability in the rat inner medullary collecting duct. | 2010 | Am. J. Physiol. Renal Physiol. | pmid:20861079 |
| Tang CH et al. | The CCL5/CCR5 axis promotes interleukin-6 production in human synovial fibroblasts. | 2010 | Arthritis Rheum. | pmid:20862675 |
| Xie MJ et al. | Evidence that apoptotic signalling in hypertrophic cardiomyocytes is determined by mitochondrial pathways involving protein kinase Cδ. | 2010 | Clin. Exp. Pharmacol. Physiol. | pmid:20880184 |
| Leverence JT et al. | Lipopolysaccharide-induced cytokine expression in alveolar epithelial cells: role of PKCζ-mediated p47phox phosphorylation. | 2011 | Chem. Biol. Interact. | pmid:20920494 |
| Koh YH et al. | Role of protein kinase C in caerulein induced expression of substance P and neurokinin-1-receptors in murine pancreatic acinar cells. | 2011 | J. Cell. Mol. Med. | pmid:20973912 |
| Shumilina E et al. | Phosphoinositide-dependent kinase PDK1 in the regulation of Ca2+ entry into mast cells. | 2010 | Cell. Physiol. Biochem. | pmid:21063107 |
| Shirasugi I et al. | Novel screening method for potential skin-whitening compounds by a luciferase reporter assay. | 2010 | Biosci. Biotechnol. Biochem. | pmid:21071833 |
| Filone CM et al. | Rift valley fever virus infection of human cells and insect hosts is promoted by protein kinase C epsilon. | 2010 | PLoS ONE | pmid:21124804 |
| Jiang W et al. | [Role of protein kinase C-delta in hyperthermia-induced apoptosis in tongue squamous cell carcinoma Tca8113 cells]. | 2010 | Hua Xi Kou Qiang Yi Xue Za Zhi | pmid:21179694 |
| Yang QE et al. | Protein kinase C delta mediates fibroblast growth factor-2-induced interferon-tau expression in bovine trophoblast. | 2011 | Biol. Reprod. | pmid:21191110 |
| da Silva Cunha KC et al. | A phospholipase Aâ‚‚ isolated from Lachesis muta snake venom increases the survival of retinal ganglion cells in vitro. | 2011 | Toxicon | pmid:21223976 |
| Lee SE et al. | Upregulation of heme oxygenase-1 as an adaptive mechanism for protection against crotonaldehyde in human umbilical vein endothelial cells. | 2011 | Toxicol. Lett. | pmid:21238556 |
| Prast-Nielsen S et al. | Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assay. | 2011 | Free Radic. Biol. Med. | pmid:21262347 |
| Zhang D et al. | Effects of manganese on tyrosine hydroxylase (TH) activity and TH-phosphorylation in a dopaminergic neural cell line. | 2011 | Toxicol. Appl. Pharmacol. | pmid:21310168 |
| Lim SC et al. | Lipid raft-dependent death receptor 5 (DR5) expression and activation are critical for ursodeoxycholic acid-induced apoptosis in gastric cancer cells. | 2011 | Carcinogenesis | pmid:21362627 |
| Schug TT | Targeting transcription through inhibition of TBP. | 2011 Jan-Feb | Oncotarget | pmid:21378415 |
| Uruno A et al. | All-trans retinoic acid and a novel synthetic retinoid tamibarotene (Am80) differentially regulate CD38 expression in human leukemia HL-60 cells: possible involvement of protein kinase C-delta. | 2011 | J. Leukoc. Biol. | pmid:21393419 |
| Valacchi G et al. | Rottlerin exhibits antiangiogenic effects in vitro. | 2011 | Chem Biol Drug Des | pmid:21435184 |
| Kim YR et al. | Apoptosis signal-regulating kinase1 is inducible by protein kinase Cδ and contributes to phorbol ester-mediated G1 phase arrest through persistent JNK activation. | 2011 | Cell Biochem. Biophys. | pmid:21468691 |
| Kim H et al. | EGFR inhibitors enhanced the susceptibility to NK cell-mediated lysis of lung cancer cells. | 2011 | J. Immunother. | pmid:21499124 |
| Ku CS et al. | Unsaturated fatty acids repress the expression of ATP-binding cassette transporter A1 in HepG2 and FHs 74 Int cells. | 2011 | Nutr Res | pmid:21530801 |
| Barbaric I et al. | High-content screening for chemical modulators of embryonal carcinoma cell differentiation and survival. | 2011 | J Biomol Screen | pmid:21593487 |
| Pabla N et al. | Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer. | 2011 | J. Clin. Invest. | pmid:21633170 |
| López-Huertas MR et al. | Protein kinase Ctheta is a specific target for inhibition of the HIV type 1 replication in CD4+ T lymphocytes. | 2011 | J. Biol. Chem. | pmid:21669868 |
| Malla N et al. | Biosynthesis of promatrix metalloproteinase-9/chondroitin sulphate proteoglycan heteromer involves a Rottlerin-sensitive pathway. | 2011 | PLoS ONE | pmid:21673806 |
| Chung YW et al. | Dual function of protein kinase C (PKC) in 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced manganese superoxide dismutase (MnSOD) expression: activation of CREB and FOXO3a by PKC-alpha phosphorylation and by PKC-mediated inactivation of Akt, respectively. | 2011 | J. Biol. Chem. | pmid:21705328 |