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Laminin 5 deposition regulates keratinocyte polarization and persistent migration. |
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Am. J. Physiol. Heart Circ. Physiol. |
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Blockade of PKCdelta proteolytic activation by loss of function mutants rescues mesencephalic dopaminergic neurons from methylcyclopentadienyl manganese tricarbonyl (MMT)-induced apoptotic cell death. |
2004 |
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Rottlerin inhibits multiple steps involved in insulin-induced glucose uptake in 3T3-L1 adipocytes. |
2004 |
Biochem. Pharmacol. |
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2004 |
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Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel. |
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The bortezomib-induced mitochondrial damage is mediated by accumulation of active protein kinase C-delta. |
2004 |
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A pathway involving protein kinase Cdelta up-regulates cytosolic phospholipase A(2)alpha in airway epithelium. |
2004 |
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Role of protein kinase C delta in reactivation of Kaposi's sarcoma-associated herpesvirus. |
2004 |
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Protein kinase C delta blocks immediate-early gene expression in senescent cells by inactivating serum response factor. |
2004 |
Mol. Cell. Biol. |
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Inhibition of Ca2+-dependent PKC isoforms unmasks ERK-dependent hypertrophic growth evoked by phenylephrine in adult ventricular cardiomyocytes. |
2004 |
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Role of protein kinase Cdelta in endothelin-induced type I collagen expression in cardiac myofibroblasts isolated from the site of myocardial infarction. |
2004 |
J. Pharmacol. Exp. Ther. |
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Regulation of CCK-induced amylase release by PKC-delta in rat pancreatic acinar cells. |
2004 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Attenuation of canine cerebral vasospasm after subarachnoid hemorrhage by protein kinase C inhibitors despite augmented phosphorylation of myosin light chain. |
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Stability of actin cytoskeleton and PKC-delta binding to actin regulate NKCC1 function in airway epithelial cells. |
2003 |
Am. J. Physiol., Cell Physiol. |
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Thrombin rapidly induces protein kinase D phosphorylation, and protein kinase C delta mediates the activation. |
2003 |
J. Biol. Chem. |
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The protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2. |
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J. Biol. Chem. |
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Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: relevance to oxidative stress and dopaminergic degeneration. |
2003 |
Neuroscience |
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Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE). |
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J. Biol. Chem. |
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Asbestos-induced apoptosis is protein kinase C delta-dependent. |
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Am. J. Respir. Cell Mol. Biol. |
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Selective stimulation of collagen synthesis in the presence of costimulatory insulin signaling by connective tissue growth factor in scleroderma fibroblasts. |
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Arthritis Rheum. |
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Induction of cIAP-2 in human colon cancer cells through PKC delta/NF-kappa B. |
2003 |
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The second phase activation of protein kinase C delta at late G1 is required for DNA synthesis in serum-induced cell cycle progression. |
2003 |
Genes Cells |
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Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation. |
2003 |
Br. J. Pharmacol. |
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Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria independent of protein kinase C. |
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Protein kinase Calpha (PKCalpha) acts upstream of PKCtheta to activate IkappaB kinase and NF-kappaB in T lymphocytes. |
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Selective roles of protein kinase C isoforms on cell motility of GT1 immortalized hypothalamic neurones. |
2003 |
J. Neuroendocrinol. |
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Protein kinase C delta is a prosurvival factor in human breast tumor cell lines. |
2003 |
Mol. Cancer Ther. |
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A calcium/calmodulin kinase pathway connects brain-derived neurotrophic factor to the cyclic AMP-responsive transcription factor in the rat hippocampus. |
2003 |
Neuroscience |
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Role of protein kinase C isoforms in rat epididymal microvascular endothelial barrier function. |
2003 |
Am. J. Respir. Cell Mol. Biol. |
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Ca(2+)-independent protein kinase C activity is required for alpha1-adrenergic-receptor-mediated regulation of ribosomal protein S6 kinases in adult cardiomyocytes. |
2003 |
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Inflammatory cytokines upregulate nephrin expression in human embryonic kidney epithelial cells and podocytes. |
2003 |
Biochem. Biophys. Res. Commun. |
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Nuclear factor of activated T cells 2 transactivation in mast cells: a novel isoform-specific transactivation domain confers unique FcepsilonRI responsiveness. |
2003 |
J. Biol. Chem. |
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Allyl alcohol activation of protein kinase C delta leads to cytotoxicity of rat hepatocytes. |
2003 |
Chem. Res. Toxicol. |
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Distinct mechanisms of receptor and nonreceptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: role of metalloprotease and protein kinase C-delta. |
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Mol. Cell. Biol. |
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Altered protein kinase C (PKC) isoforms in non-small cell lung cancer cells: PKCdelta promotes cellular survival and chemotherapeutic resistance. |
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Cancer Res. |
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Thrombin stimulation of vascular adhesion molecule-1 in endothelial cells is mediated by protein kinase C (PKC)-delta-NF-kappa B and PKC-zeta-GATA signaling pathways. |
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J. Biol. Chem. |
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Effect of detergent on "promiscuous" inhibitors. |
2003 |
J. Med. Chem. |
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Role of PKC-delta activity in glutathione-depleted neuroblastoma cells. |
2003 |
Free Radic. Biol. Med. |
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A generic time-resolved fluorescence assay for serine/threonine kinase activity: application to Cdc7/Dbf4. |
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Okadaic acid induces sustained activation of NFkappaB and degradation of the nuclear IkappaBalpha in human neutrophils. |
2003 |
Arch. Biochem. Biophys. |
pmid:12921778
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Rottlerin, an inhibitor of protein kinase Cdelta (PKCdelta), inhibits astrocytic glutamate transport activity and reduces GLAST immunoreactivity by a mechanism that appears to be PKCdelta-independent. |
2003 |
J. Neurochem. |
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Dopaminergic inhibition of secretin-stimulated choleresis by increased PKC-gamma expression and decrease of PKA activity. |
2003 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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The c-Jun N-terminal kinase 1 activity is differentially regulated by specific mechanisms during apoptosis. |
2003 |
J. Biol. Chem. |
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Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR-induced Fas ligand expression. |
2003 |
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Induction of apoptosis by Se-MSC in U937 human leukemia cells through release of cytochrome c and activation of caspases and PKC-delta: mutual regulation between caspases and PKC-delta via a positive feedback mechanism. |
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A novel role of protein kinase C-delta in cell signaling triggered by glutathione depletion. |
2003 |
Biochem. Pharmacol. |
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Distinct isoforms of protein kinase C are involved in human eosinophil functions induced by platelet-activating factor. |
2003 |
Int. Arch. Allergy Immunol. |
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