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Protein kinase C delta stimulates antigen presentation by Class II MHC in murine dendritic cells. |
2007 |
Int. Immunol. |
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2007 |
Anal. Chem. |
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N-Acetylcysteine and alpha-cyano-4-hydroxycinnamic acid alter protein kinase C (PKC)-delta and PKC-zeta and diminish dysmorphogenesis in rat embryos cultured with high glucose in vitro. |
2007 |
J. Endocrinol. |
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Protein kinase Calpha is differentially activated during neonatal and adult erythropoiesis and favors expression of a reporter gene under the control of the (A)gamma globin-promoter in cellular models of hemoglobin switching. |
2007 |
J. Cell. Biochem. |
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Delta-opioid receptor activation before ischemia reduces gap junction permeability in ischemic myocardium by PKC-epsilon-mediated phosphorylation of connexin 43. |
2007 |
Am. J. Physiol. Heart Circ. Physiol. |
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Neuroprotective effect of protein kinase C delta inhibitor rottlerin in cell culture and animal models of Parkinson's disease. |
2007 |
J. Pharmacol. Exp. Ther. |
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Effect of PKC isozyme inhibition on forskolin-induced activation of BKCa channels in rat pulmonary arterial smooth muscle. |
2006 Mar-Apr |
Lung |
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[Phosphorylation of PKCdelta participates in the toxicity of 6-hydroxydopamine on dopaminergic neuroblastoma cell]. |
2006 |
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Increasing ornithine decarboxylase activity is another way of prolactin preventing methotrexate-induced apoptosis: crosstalk between ODC and BCL-2. |
2006 |
Apoptosis |
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Suguro T et al. |
Serotonin acts as an up-regulator of acyl-coenzyme A:cholesterol acyltransferase-1 in human monocyte-macrophages. |
2006 |
Atherosclerosis |
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Role of PKC isoforms in the Fc(gamma)R-mediated inhibition of LPS-stimulated IL-12 secretion by macrophages. |
2006 |
J. Leukoc. Biol. |
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Regulation of radiation-induced protein kinase Cdelta activation in radiation-induced apoptosis differs between radiosensitive and radioresistant mouse thymic lymphoma cell lines. |
2006 |
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2006 |
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Rottlerin inhibits stimulated enzymatic secretion and several intracellular signaling transduction pathways in pancreatic acinar cells by a non-PKC-delta-dependent mechanism. |
2006 |
Biochim. Biophys. Acta |
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Collins NT et al. |
Cyclic strain-mediated regulation of vascular endothelial occludin and ZO-1: influence on intercellular tight junction assembly and function. |
2006 |
Arterioscler. Thromb. Vasc. Biol. |
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Andreeva AY et al. |
Assembly of tight junction is regulated by the antagonism of conventional and novel protein kinase C isoforms. |
2006 |
Int. J. Biochem. Cell Biol. |
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Hughes PJ et al. |
Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARalpha and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways. |
2006 |
J. Cell. Biochem. |
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Hsieh HL et al. |
BK-induced cytosolic phospholipase A2 expression via sequential PKC-delta, p42/p44 MAPK, and NF-kappaB activation in rat brain astrocytes. |
2006 |
J. Cell. Physiol. |
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Jane EP et al. |
Coadministration of sorafenib with rottlerin potently inhibits cell proliferation and migration in human malignant glioma cells. |
2006 |
J. Pharmacol. Exp. Ther. |
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Mallotoxin is a novel human ether-a-go-go-related gene (hERG) potassium channel activator. |
2006 |
J. Pharmacol. Exp. Ther. |
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PKCdelta regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation. |
2006 |
Blood |
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Shukla A et al. |
Transcriptional up-regulation of MMP12 and MMP13 by asbestos occurs via a PKCdelta-dependent pathway in murine lung. |
2006 |
FASEB J. |
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Rushworth SA et al. |
Role of protein kinase C delta in curcumin-induced antioxidant response element-mediated gene expression in human monocytes. |
2006 |
Biochem. Biophys. Res. Commun. |
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Mechanisms of apoptosis-induction by rottlerin: therapeutic implications for B-CLL. |
2006 |
Leukemia |
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Infarct-sparing effect of myocardial postconditioning is dependent on protein kinase C signalling. |
2006 |
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Involvement of mitogen-activated protein kinases and protein kinase C in regulation of antioxidant response element activity in human keratinocytes. |
2006 |
Cancer Lett. |
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Regulation of CD93 cell surface expression by protein kinase C isoenzymes. |
2006 |
Microbiol. Immunol. |
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Effect of protein kinase C inhibitors on porcine oocyte activation. |
2006 |
J. Exp. Zoolog. Part A Comp. Exp. Biol. |
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Involvement of protein kinase Cdelta in the activation of NADPH oxidase and the phagocytosis of neutrophils. |
2006 |
Free Radic. Res. |
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Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence. |
2006 |
Nat. Cell Biol. |
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Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis. |
2006 |
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Different roles of protein kinase C-betaI and -delta in the regulation of adipocyte differentiation. |
2006 |
Int. J. Biochem. Cell Biol. |
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STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-alpha. |
2006 |
J. Immunol. |
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Interpreting steep dose-response curves in early inhibitor discovery. |
2006 |
J. Med. Chem. |
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Evidence that phospholipase-C-dependent, calcium-independent mechanisms are required for directional migration of T-lymphocytes in response to the CCR4 ligands CCL17 and CCL22. |
2006 |
J. Leukoc. Biol. |
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Involvement of protein kinase C delta in the alteration of mitochondrial mass in human cells under oxidative stress. |
2006 |
Free Radic. Biol. Med. |
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Contact inhibition causes strong downregulation of expression of MICA in human fibroblasts and decreased NK cell killing. |
2006 |
Hum. Immunol. |
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Multiple actions of lysophosphatidylcholine in human Jurkat T cells. |
2006 |
Acta Pharmacol. Sin. |
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Rottlerin, a specific inhibitor of protein kinase C-delta, impedes barrier repair response by increasing intracellular free calcium. |
2006 |
J. Invest. Dermatol. |
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[The effect of PKC-delta inhibitor Rottlerin on human colon cancer cell line SW1116 and its mechanism]. |
2006 |
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Acetaldehyde inhibits PPARgamma via H2O2-mediated c-Abl activation in human hepatic stellate cells. |
2006 |
Gastroenterology |
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Shoenfelt JL and Fenton MJ |
TLR2- and TLR4-dependent activation of STAT1 serine phosphorylation in murine macrophages is protein kinase C-delta-independent. |
2006 |
J. Endotoxin Res. |
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Piceatannol upregulates endothelial heme oxygenase-1 expression via novel protein kinase C and tyrosine kinase pathways. |
2006 |
Pharmacol. Res. |
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Lysophosphatidic acid-induced changes in cAMP profiles in young and senescent human fibroblasts as a clue to the ageing process. |
2006 |
Mech. Ageing Dev. |
pmid:16516270
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Mechanism of endothelin-1 activation of MAP kinases in neonatal pulmonary vascular smooth muscle. |
2005 Nov-Dec |
Lung |
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Interactive role of protein kinase C-delta with rho-kinase in the development of cerebral vasospasm in a canine two-hemorrhage model. |
2005 Jan-Feb |
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Upregulation of PKC-delta contributes to antiestrogen resistance in mammary tumor cells. |
2005 |
Oncogene |
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Central role of PKCdelta in glycoxidation-dependent apoptosis of human neurons. |
2005 |
Free Radic. Biol. Med. |
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Cooperation of amphiregulin and insulin-like growth factor-1 inhibits Bax- and Bad-mediated apoptosis via a protein kinase C-dependent pathway in non-small cell lung cancer cells. |
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Fast modulation of heat-activated ionic current by proinflammatory interleukin 6 in rat sensory neurons. |
2005 |
Brain |
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Phosphorylation-regulated nucleocytoplasmic trafficking of internalized fibroblast growth factor-1. |
2005 |
Mol. Biol. Cell |
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Phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells. |
2005 |
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Selective inhibition by rottlerin of macropinocytosis in monocyte-derived dendritic cells. |
2005 |
Immunology |
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NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels. |
2005 |
EMBO J. |
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Immunomodulatory drugs (IMiDs) increase the production of IL-2 from stimulated T cells by increasing PKC-theta activation and enhancing the DNA-binding activity of AP-1 but not NF-kappaB, OCT-1, or NF-AT. |
2005 |
J. Interferon Cytokine Res. |
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Differential CCR1-mediated chemotaxis signaling induced by human CC chemokine HCC-4/CCL16 in HOS cells. |
2005 |
FEBS Lett. |
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Interferon-alpha-induced expression of phospholipid scramblase 1 through STAT1 requires the sequential activation of protein kinase Cdelta and JNK. |
2005 |
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Caspase-3-dependent protein kinase C delta activity is required for the progression of Ginsenoside-Rh2-induced apoptosis in SK-HEP-1 cells. |
2005 |
Cancer Lett. |
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Woo CH et al. |
VCAM-1 upregulation via PKCdelta-p38 kinase-linked cascade mediates the TNF-alpha-induced leukocyte adhesion and emigration in the lung airway epithelium. |
2005 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:15489375
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Lewis AE et al. |
Protein kinase C delta is not activated by caspase-3 and its inhibition is sufficient to induce apoptosis in the colon cancer line, COLO 205. |
2005 |
Cell. Signal. |
pmid:15494216
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Zhang J et al. |
PKCdelta protects human breast tumor MCF-7 cells against tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis. |
2005 |
J. Cell. Biochem. |
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Brown JM et al. |
Effects of rottlerin on silica-exacerbated systemic autoimmune disease in New Zealand mixed mice. |
2005 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
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Gefitinib ("Iressa", ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells. |
2005 |
Cancer Chemother. Pharmacol. |
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Rao PE et al. |
Differentiation and expansion of T cells with regulatory function from human peripheral lymphocytes by stimulation in the presence of TGF-{beta}. |
2005 |
J. Immunol. |
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Luminal leptin induces rapid inhibition of active intestinal absorption of glucose mediated by sodium-glucose cotransporter 1. |
2005 |
Diabetes |
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Ahmed S et al. |
Protein kinase Ctheta activity is involved in the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced signal transduction pathway leading to apoptosis in L-MAT, a human lymphoblastic T-cell line. |
2005 |
FEBS J. |
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Fan CY et al. |
PKCdelta mediates up-regulation of NOX1, a catalytic subunit of NADPH oxidase, via transactivation of the EGF receptor: possible involvement of PKCdelta in vascular hypertrophy. |
2005 |
Biochem. J. |
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Panaretakis T et al. |
Doxorubicin requires the sequential activation of caspase-2, protein kinase Cdelta, and c-Jun NH2-terminal kinase to induce apoptosis. |
2005 |
Mol. Biol. Cell |
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Tse SM et al. |
Accumulation of diacylglycerol in the Chlamydia inclusion vacuole: possible role in the inhibition of host cell apoptosis. |
2005 |
J. Biol. Chem. |
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Miguel BG et al. |
Regulation of cadmium-induced apoptosis by PKCdelta in U937 human promonocytic cells. |
2005 |
Biochim. Biophys. Acta |
pmid:15843035
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Liao YF et al. |
The PKC delta inhibitor, rottlerin, induces apoptosis of haematopoietic cell lines through mitochondrial membrane depolarization and caspases' cascade. |
2005 |
Life Sci. |
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Roose JP et al. |
A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells. |
2005 |
Mol. Cell. Biol. |
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Zakharov SI et al. |
Activation of the BK (SLO1) potassium channel by mallotoxin. |
2005 |
J. Biol. Chem. |
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Avila GE et al. |
Inhibitory effects of 12-O-tetradecanoylphorbol-13-acetate alone or in combination with all-trans retinoic acid on the growth of cultured human pancreas cancer cells and pancreas tumor xenografts in immunodeficient mice. |
2005 |
J. Pharmacol. Exp. Ther. |
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Chen S et al. |
Positive and negative transcriptional regulation of aromatase expression in human breast cancer tissue. |
2005 |
J. Steroid Biochem. Mol. Biol. |
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Tepperman BL et al. |
Effect of protein kinase C activation on intracellular Ca2+ signaling and integrity of intestinal epithelial cells. |
2005 |
Eur. J. Pharmacol. |
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Yamaguchi K et al. |
Signal transduction through substance P receptor in human glioblastoma cells: roles for Src and PKCdelta. |
2005 |
Cancer Chemother. Pharmacol. |
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Skaletz-Rorowski A et al. |
PKC delta-induced activation of MAPK pathway is required for bFGF-stimulated proliferation of coronary smooth muscle cells. |
2005 |
Cardiovasc. Res. |
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Kim DC et al. |
Effect of rottlerin, a PKC-delta inhibitor, on TLR-4-dependent activation of murine microglia. |
2005 |
Biochem. Biophys. Res. Commun. |
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Styles NA et al. |
Phosphorylation and down-regulation of Bim by muscarinic cholinergic receptor activation via protein kinase C. |
2005 |
Neurochem. Int. |
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Kim EH et al. |
Rottlerin sensitizes glioma cells to TRAIL-induced apoptosis by inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP. |
2005 |
Oncogene |
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Laminin 5 deposition regulates keratinocyte polarization and persistent migration. |
2004 |
J. Cell. Sci. |
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Expression of adhesion molecules by sphingosine 1-phosphate and histamine in endothelial cells. |
2004 |
Eur. J. Pharmacol. |
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Rao VU et al. |
PKC-epsilon regulation of extracellular signal-regulated kinase: a potential role in phenylephrine-induced cardiocyte growth. |
2004 |
Am. J. Physiol. Heart Circ. Physiol. |
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Cummings R et al. |
Protein kinase Cdelta mediates lysophosphatidic acid-induced NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells. |
2004 |
J. Biol. Chem. |
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Tan M et al. |
Angiotensin II-induced protein kinase D activation is regulated by protein kinase Cdelta and mediated via the angiotensin II type 1 receptor in vascular smooth muscle cells. |
2004 |
Arterioscler. Thromb. Vasc. Biol. |
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Welters HJ et al. |
Evidence that protein kinase Cdelta is not required for palmitate-induced cytotoxicity in BRIN-BD11 beta-cells. |
2004 |
J. Mol. Endocrinol. |
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Anantharam V et al. |
Blockade of PKCdelta proteolytic activation by loss of function mutants rescues mesencephalic dopaminergic neurons from methylcyclopentadienyl manganese tricarbonyl (MMT)-induced apoptotic cell death. |
2004 |
Ann. N. Y. Acad. Sci. |
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Huda R et al. |
Selective activation of protein kinase C delta in human neutrophils following ischemia reperfusion of skeletal muscle. |
2004 |
Shock |
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Bazuine M et al. |
Rottlerin inhibits multiple steps involved in insulin-induced glucose uptake in 3T3-L1 adipocytes. |
2004 |
Biochem. Pharmacol. |
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Deszo EL et al. |
IL-4-dependent CD86 expression requires JAK/STAT6 activation and is negatively regulated by PKCdelta. |
2004 |
Cell. Signal. |
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Ryazanova LV et al. |
Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel. |
2004 |
J. Biol. Chem. |
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Iwabu A et al. |
Epidermal growth factor induces fibroblast contractility and motility via a protein kinase C delta-dependent pathway. |
2004 |
J. Biol. Chem. |
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Sussmann M et al. |
Induction of hyaluronic acid synthase 2 (HAS2) in human vascular smooth muscle cells by vasodilatory prostaglandins. |
2004 |
Circ. Res. |
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Kajimoto T et al. |
Ceramide-induced apoptosis by translocation, phosphorylation, and activation of protein kinase Cdelta in the Golgi complex. |
2004 |
J. Biol. Chem. |
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Woo CH et al. |
Lipopolysaccharide induces matrix metalloproteinase-9 expression via a mitochondrial reactive oxygen species-p38 kinase-activator protein-1 pathway in Raw 264.7 cells. |
2004 |
J. Immunol. |
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Kang HS et al. |
Receptor activator of nuclear factor-kappaB is induced by a rottlerin-sensitive and p38 MAP kinase-dependent pathway during monocyte differentiation. |
2004 |
Mol. Cells |
pmid:15232218
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Lladó A et al. |
Protein kinaseCdelta-calmodulin crosstalk regulates epidermal growth factor receptor exit from early endosomes. |
2004 |
Mol. Biol. Cell |
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Cho CH et al. |
Localization of VEGFR-2 and PLD2 in endothelial caveolae is involved in VEGF-induced phosphorylation of MEK and ERK. |
2004 |
Am. J. Physiol. Heart Circ. Physiol. |
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