Bae JH et al. |
Susceptibility to natural killer cell-mediated lysis of colon cancer cells is enhanced by treatment with epidermal growth factor receptor inhibitors through UL16-binding protein-1 induction. |
2012 |
Cancer Sci. |
pmid:21951556
|
Guo D et al. |
Protein kinase Cα and integrin-linked kinase mediate the negative axon guidance effects of Sonic hedgehog. |
2012 |
Mol. Cell. Neurosci. |
pmid:22521536
|
Contreras X et al. |
Protein kinase C-delta regulates HIV-1 replication at an early post-entry step in macrophages. |
2012 |
Retrovirology |
pmid:22554282
|
Lee YS and Choi EM |
Effect of pollen from Typha angustata on hydrogen peroxide induced toxicity in osteoblastic MC3T3-E1 cells. |
2012 |
J. Oral Pathol. Med. |
pmid:21958211
|
Brutman-Barazani T et al. |
Protein kinase Cδ but not PKCα is involved in insulin-induced glucose metabolism in hepatocytes. |
2012 |
J. Cell. Biochem. |
pmid:22271577
|
Maioli E et al. |
Rottlerin and cancer: novel evidence and mechanisms. |
2012 |
ScientificWorldJournal |
pmid:22272173
|
Sugawara T et al. |
PKCδ and ε regulate the morphological integrity of the ER-Golgi intermediate compartment (ERGIC) but not the anterograde and retrograde transports via the Golgi apparatus. |
2012 |
Biochim. Biophys. Acta |
pmid:22326427
|
Furuya T et al. |
Role of retinal glial cell glutamate transporters in retinal ganglion cell survival following stimulation of NMDA receptor. |
2012 |
Curr. Eye Res. |
pmid:22335803
|
Deng B et al. |
Inhibition of protein kinase C β(2) prevents tumor necrosis factor-α-induced apoptosis and oxidative stress in endothelial cells: the role of NADPH oxidase subunits. |
2012 |
J. Vasc. Res. |
pmid:22261918
|
Chang WT et al. |
Protein kinase C delta-mediated cytoskeleton remodeling is involved in aloe-emodin-induced photokilling of human lung cancer cells. |
2012 |
Anticancer Res. |
pmid:22993309
|
Lei L et al. |
Rottlerin-mediated inhibition of Chlamydia trachomatis growth and uptake of sphingolipids is independent of p38-regulated/activated protein kinase (PRAK). |
2012 |
PLoS ONE |
pmid:22970301
|
Ku CS et al. |
Unsaturated fatty acids repress expression of ATP binding cassette transporter A1 and G1 in RAW 264.7 macrophages. |
2012 |
J. Nutr. Biochem. |
pmid:22209005
|
Tcatchoff L et al. |
Annexin A1 and A2: roles in retrograde trafficking of Shiga toxin. |
2012 |
PLoS ONE |
pmid:22792315
|
Mooi LY et al. |
Suppressive effect of maslinic acid on PMA-induced protein kinase C in human B-lymphoblastoid cells. |
2012 |
Asian Pac. J. Cancer Prev. |
pmid:22799301
|
Li Z et al. |
Role of PKC-ERK signaling in tamoxifen-induced apoptosis and tamoxifen resistance in human breast cancer cells. |
2012 |
Oncol. Rep. |
pmid:22427054
|
Shin EJ et al. |
Role of oxidative stress in methamphetamine-induced dopaminergic toxicity mediated by protein kinase Cδ. |
2012 |
Behav. Brain Res. |
pmid:22512859
|
Latorre E et al. |
Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells. |
2012 |
Mol. Cancer |
pmid:22436134
|
Haines RJ et al. |
Protein kinase Cα phosphorylates a novel argininosuccinate synthase site at serine 328 during calcium-dependent stimulation of endothelial nitric-oxide synthase in vascular endothelial cells. |
2012 |
J. Biol. Chem. |
pmid:22696221
|
Huang CY et al. |
Thrombin induces epidermal growth factor receptor transactivation and CCL2 expression in human osteoblasts. |
2012 |
Arthritis Rheum. |
pmid:22674286
|
Alapati K et al. |
uPAR and cathepsin B knockdown inhibits radiation-induced PKC integrated integrin signaling to the cytoskeleton of glioma-initiating cells. |
2012 |
Int. J. Oncol. |
pmid:22641287
|
Kolasa E et al. |
Phorbol ester-modulation of estrogenic genomic effects triggered by the environmental contaminant benzanthracene. |
2012 |
Toxicol In Vitro |
pmid:22643241
|
Yun N et al. |
Differential consequences of protein kinase C activation during early and late hepatic ischemic preconditioning. |
2012 |
J Physiol Sci |
pmid:22359070
|
Lim JH et al. |
Rottlerin induces apoptosis of HT29 colon carcinoma cells through NAG-1 upregulation via an ERK and p38 MAPK-dependent and PKC δ-independent mechanism. |
2012 |
Chem. Biol. Interact. |
pmid:22410117
|
Hsu YC et al. |
Ciliogenic RFX transcription factors regulate FGF1 gene promoter. |
2012 |
J. Cell. Biochem. |
pmid:22415835
|
Singh BN et al. |
Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR pathway in human pancreatic cancer stem cells. |
2012 |
Biochem. Pharmacol. |
pmid:22902833
|
Chen RX et al. |
Neuromedin S increases L-type Ca(2+) channel currents through G(i)α-protein and phospholipase C-dependent novel protein kinase C delta pathway in adult rat ventricular myocytes. |
2012 |
Cell. Physiol. Biochem. |
pmid:22832358
|
Okuwa H et al. |
Sphingosine suppresses mesothelioma cell proliferation by inhibiting PKC-δ and inducing cell cycle arrest at the G(0)/G(1) phase. |
2012 |
Cell. Physiol. Biochem. |
pmid:23221613
|
Kim YS et al. |
Glycoxidised LDL induced the upregulation of Axl receptor tyrosine kinase and its ligand in mouse mesangial cells. |
2012 |
PLoS ONE |
pmid:23226259
|
Chen BR et al. |
Quiescent fibroblasts are more active in mounting robust inflammatory responses than proliferative fibroblasts. |
2012 |
PLoS ONE |
pmid:23155470
|
Lin YM et al. |
The CCL2/CCR2 axis enhances vascular cell adhesion molecule-1 expression in human synovial fibroblasts. |
2012 |
PLoS ONE |
pmid:23185512
|
Barrias ES et al. |
Trypanosoma cruzi uses macropinocytosis as an additional entry pathway into mammalian host cell. |
2012 |
Microbes Infect. |
pmid:23010292
|
Lin W et al. |
Induction of cell cycle arrest by the carbazole alkaloid Clauszoline-I from Clausena vestita D. D. Tao via inhibition of the PKCδ phosphorylation. |
2012 |
Eur J Med Chem |
pmid:22093759
|
Koh YH et al. |
Activation of neurokinin-1 receptors up-regulates substance P and neurokinin-1 receptor expression in murine pancreatic acinar cells. |
2012 |
J. Cell. Mol. Med. |
pmid:22040127
|
Jäntti MH et al. |
OX1 orexin/hypocretin receptor activation of phospholipase D. |
2012 |
Br. J. Pharmacol. |
pmid:21718304
|
Schug TT |
Targeting transcription through inhibition of TBP. |
2011 Jan-Feb |
Oncotarget |
pmid:21378415
|
Ko NY et al. |
Interleukin-32α production is regulated by MyD88-dependent and independent pathways in IL-1β-stimulated human alveolar epithelial cells. |
2011 Jan-Feb |
Immunobiology |
pmid:20430472
|
Kim H et al. |
EGFR inhibitors enhanced the susceptibility to NK cell-mediated lysis of lung cancer cells. |
2011 |
J. Immunother. |
pmid:21499124
|
Chung YW et al. |
Dual function of protein kinase C (PKC) in 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced manganese superoxide dismutase (MnSOD) expression: activation of CREB and FOXO3a by PKC-alpha phosphorylation and by PKC-mediated inactivation of Akt, respectively. |
2011 |
J. Biol. Chem. |
pmid:21705328
|
Li S et al. |
Protein kinase C mediates peroxynitrite toxicity to oligodendrocytes. |
2011 |
Mol. Cell. Neurosci. |
pmid:21708260
|
Malla N et al. |
Biosynthesis of promatrix metalloproteinase-9/chondroitin sulphate proteoglycan heteromer involves a Rottlerin-sensitive pathway. |
2011 |
PLoS ONE |
pmid:21673806
|
López-Huertas MR et al. |
Protein kinase Ctheta is a specific target for inhibition of the HIV type 1 replication in CD4+ T lymphocytes. |
2011 |
J. Biol. Chem. |
pmid:21669868
|
Pabla N et al. |
Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer. |
2011 |
J. Clin. Invest. |
pmid:21633170
|
Valacchi G et al. |
Rottlerin exhibits antiangiogenic effects in vitro. |
2011 |
Chem Biol Drug Des |
pmid:21435184
|
Uruno A et al. |
All-trans retinoic acid and a novel synthetic retinoid tamibarotene (Am80) differentially regulate CD38 expression in human leukemia HL-60 cells: possible involvement of protein kinase C-delta. |
2011 |
J. Leukoc. Biol. |
pmid:21393419
|
Ku CS et al. |
Unsaturated fatty acids repress the expression of ATP-binding cassette transporter A1 in HepG2 and FHs 74 Int cells. |
2011 |
Nutr Res |
pmid:21530801
|
Kim YR et al. |
Apoptosis signal-regulating kinase1 is inducible by protein kinase Cδ and contributes to phorbol ester-mediated G1 phase arrest through persistent JNK activation. |
2011 |
Cell Biochem. Biophys. |
pmid:21468691
|
Leverence JT et al. |
Lipopolysaccharide-induced cytokine expression in alveolar epithelial cells: role of PKCζ-mediated p47phox phosphorylation. |
2011 |
Chem. Biol. Interact. |
pmid:20920494
|
Park EJ and Kwon TK |
Rottlerin enhances IL-1β-induced COX-2 expression through sustained p38 MAPK activation in MDA-MB-231 human breast cancer cells. |
2011 |
Exp. Mol. Med. |
pmid:21971413
|
Koh YH et al. |
Role of protein kinase C in caerulein induced expression of substance P and neurokinin-1-receptors in murine pancreatic acinar cells. |
2011 |
J. Cell. Mol. Med. |
pmid:20973912
|
Chen Z et al. |
Protein kinase Cδ inactivation inhibits cellular proliferation and decreases survival in human neuroendocrine tumors. |
2011 |
Endocr. Relat. Cancer |
pmid:21990324
|
Prast-Nielsen S et al. |
Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assay. |
2011 |
Free Radic. Biol. Med. |
pmid:21262347
|
da Silva Cunha KC et al. |
A phospholipase Aâ‚‚ isolated from Lachesis muta snake venom increases the survival of retinal ganglion cells in vitro. |
2011 |
Toxicon |
pmid:21223976
|
Lee SE et al. |
Upregulation of heme oxygenase-1 as an adaptive mechanism for protection against crotonaldehyde in human umbilical vein endothelial cells. |
2011 |
Toxicol. Lett. |
pmid:21238556
|
Yang QE et al. |
Protein kinase C delta mediates fibroblast growth factor-2-induced interferon-tau expression in bovine trophoblast. |
2011 |
Biol. Reprod. |
pmid:21191110
|
Barbaric I et al. |
High-content screening for chemical modulators of embryonal carcinoma cell differentiation and survival. |
2011 |
J Biomol Screen |
pmid:21593487
|
Matta C et al. |
PKCdelta is a positive regulator of chondrogenesis in chicken high density micromass cell cultures. |
2011 |
Biochimie |
pmid:20850497
|
Zhang D et al. |
Effects of manganese on tyrosine hydroxylase (TH) activity and TH-phosphorylation in a dopaminergic neural cell line. |
2011 |
Toxicol. Appl. Pharmacol. |
pmid:21310168
|
Lim SC et al. |
Lipid raft-dependent death receptor 5 (DR5) expression and activation are critical for ursodeoxycholic acid-induced apoptosis in gastric cancer cells. |
2011 |
Carcinogenesis |
pmid:21362627
|
Wermuth PJ et al. |
Effect of protein kinase C delta (PKC-δ) inhibition on the transcriptome of normal and systemic sclerosis human dermal fibroblasts in vitro. |
2011 |
PLoS ONE |
pmid:22096525
|
Tsai RK et al. |
PKCδ-dependent signaling mediates ethambutol-induced toxic effects on human retinal pigment cells. |
2011 |
Mol. Vis. |
pmid:21738386
|
Lawal AO and Ellis EM |
Nrf2-mediated adaptive response to cadmium-induced toxicity involves protein kinase C delta in human 1321N1 astrocytoma cells. |
2011 |
Environ. Toxicol. Pharmacol. |
pmid:21787730
|
Clements RT et al. |
Rottlerin increases cardiac contractile performance and coronary perfusion through BKCa++ channel activation after cold cardioplegic arrest in isolated hearts. |
2011 |
Circulation |
pmid:21911819
|
Sarkar N et al. |
Rottlerin dissolves pre-formed protein amyloid: a study on hen egg white lysozyme. |
2011 |
Biochim. Biophys. Acta |
pmid:21723915
|
Shirasugi I et al. |
Novel screening method for potential skin-whitening compounds by a luciferase reporter assay. |
2010 |
Biosci. Biotechnol. Biochem. |
pmid:21071833
|
Das J et al. |
Protective role of taurine against arsenic-induced mitochondria-dependent hepatic apoptosis via the inhibition of PKCdelta-JNK pathway. |
2010 |
PLoS ONE |
pmid:20830294
|
Filone CM et al. |
Rift valley fever virus infection of human cells and insect hosts is promoted by protein kinase C epsilon. |
2010 |
PLoS ONE |
pmid:21124804
|
Wang Y et al. |
Protein kinase C regulates urea permeability in the rat inner medullary collecting duct. |
2010 |
Am. J. Physiol. Renal Physiol. |
pmid:20861079
|
Tang CH et al. |
The CCL5/CCR5 axis promotes interleukin-6 production in human synovial fibroblasts. |
2010 |
Arthritis Rheum. |
pmid:20862675
|
Xie MJ et al. |
Evidence that apoptotic signalling in hypertrophic cardiomyocytes is determined by mitochondrial pathways involving protein kinase Cδ. |
2010 |
Clin. Exp. Pharmacol. Physiol. |
pmid:20880184
|
Jiang W et al. |
[Role of protein kinase C-delta in hyperthermia-induced apoptosis in tongue squamous cell carcinoma Tca8113 cells]. |
2010 |
Hua Xi Kou Qiang Yi Xue Za Zhi |
pmid:21179694
|
Kim KM et al. |
Puerarin suppresses AGEs-induced inflammation in mouse mesangial cells: a possible pathway through the induction of heme oxygenase-1 expression. |
2010 |
Toxicol. Appl. Pharmacol. |
pmid:20060010
|
Ohno I et al. |
Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family. |
2010 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:19762431
|
Lin CJ et al. |
Rottlerin inhibits migration of follicular thyroid carcinoma cells by PKCdelta-independent destabilization of the focal adhesion complex. |
2010 |
J. Cell. Biochem. |
pmid:20225271
|
Li X et al. |
PKC-delta promotes renal tubular cell apoptosis associated with proteinuria. |
2010 |
J. Am. Soc. Nephrol. |
pmid:20395372
|
Mertens-Walker I et al. |
Gonadotropin-induced ovarian cancer cell migration and proliferation require extracellular signal-regulated kinase 1/2 activation regulated by calcium and protein kinase C{delta}. |
2010 |
Endocr. Relat. Cancer |
pmid:20215102
|
Park EJ et al. |
Rottlerin induces heme oxygenase-1 (HO-1) up-regulation through reactive oxygen species (ROS) dependent and PKC delta-independent pathway in human colon cancer HT29 cells. |
2010 |
Biochimie |
pmid:19833168
|
Leppänen T et al. |
Inhibition of protein kinase Cdelta reduces tristetraprolin expression by destabilizing its mRNA in activated macrophages. |
2010 |
Eur. J. Pharmacol. |
pmid:19925787
|
Bhatt KH et al. |
Protein kinase Cdelta and protein tyrosine kinase regulate peptidoglycan-induced nuclear factor-kappaB activation and inducible nitric oxide synthase expression in mouse peritoneal macrophages in vitro. |
2010 |
Mol. Immunol. |
pmid:19931912
|
Rohilla A et al. |
Possible involvement of PKC-delta in the abrogated cardioprotective potential of ischemic preconditioning in hyperhomocysteinemic rat hearts. |
2010 |
Biomed. Pharmacother. |
pmid:19914792
|
Shen SM et al. |
Downregulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells. |
2010 |
Carcinogenesis |
pmid:20015864
|
McEneaney V et al. |
Protein kinase D stabilizes aldosterone-induced ERK1/2 MAP kinase activation in M1 renal cortical collecting duct cells to promote cell proliferation. |
2010 |
J. Steroid Biochem. Mol. Biol. |
pmid:19804826
|
Behl M et al. |
Lead-induced accumulation of beta-amyloid in the choroid plexus: role of low density lipoprotein receptor protein-1 and protein kinase C. |
2010 |
Neurotoxicology |
pmid:20488202
|
Hwang YP et al. |
3-Caffeoyl, 4-dihydrocaffeoylquinic acid from Salicornia herbacea inhibits tumor cell invasion by regulating protein kinase C-delta-dependent matrix metalloproteinase-9 expression. |
2010 |
Toxicol. Lett. |
pmid:20599481
|
Lanaspa MA et al. |
The expression of aquaporin-1 in the medulla of the kidney is dependent on the transcription factor associated with hypertonicity, TonEBP. |
2010 |
J. Biol. Chem. |
pmid:20639513
|
Maioli E and Valacchi G |
Rottlerin: bases for a possible usage in psoriasis. |
2010 |
Curr. Drug Metab. |
pmid:20540694
|
Arisaka M et al. |
Involvement of protein kinase Cdelta in induction of apoptosis by cationic liposomes in macrophage-like RAW264.7 cells. |
2010 |
FEBS Lett. |
pmid:20122929
|
Wallerstedt E et al. |
Protein kinase C-delta is involved in the inflammatory effect of IL-6 in mouse adipose cells. |
2010 |
Diabetologia |
pmid:20151299
|
Liu J et al. |
The effect of PKC activation and inhibition on osteogenic differentiation of human mesenchymal stem cells. |
2010 |
J Tissue Eng Regen Med |
pmid:20033927
|
Shumilina E et al. |
Phosphoinositide-dependent kinase PDK1 in the regulation of Ca2+ entry into mast cells. |
2010 |
Cell. Physiol. Biochem. |
pmid:21063107
|
Lee HG and Yang JH |
PKC-δ mediates TCDD-induced apoptosis of chondrocyte in ROS-dependent manner. |
2010 |
Chemosphere |
pmid:20846705
|
Jang BC |
Induction of COX-2 in human airway cells by manganese: role of PI3K/PKB, p38 MAPK, PKCs, Src, and glutathione depletion. |
2009 |
Toxicol In Vitro |
pmid:19084589
|
Valacchi G et al. |
Rottlerin: a multifaced regulator of keratinocyte cell cycle. |
2009 |
Exp. Dermatol. |
pmid:19492998
|
Nguyen KT et al. |
Rottlerin inhibits (Na+, K+)-ATPase activity in brain tissue and alters D-aspartate dependent redistribution of glutamate transporter GLAST in cultured astrocytes. |
2009 |
Neurochem. Res. |
pmid:19495968
|
Liu CY et al. |
Activation of PKCdelta and ERK1/2 in the sensitivity to UV-induced apoptosis of human cells harboring 4977 bp deletion of mitochondrial DNA. |
2009 |
Biochim. Biophys. Acta |
pmid:19477272
|
Hufnagel H et al. |
Fluid phase endocytosis contributes to transfection of DNA by PEI-25. |
2009 |
Mol. Ther. |
pmid:19532143
|
Chintalgattu V and Katwa LC |
Role of protein kinase C-delta in angiotensin II induced cardiac fibrosis. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19540196
|
Fordjour AK and Harrington EO |
PKCdelta influences p190 phosphorylation and activity: events independent of PKCdelta-mediated regulation of endothelial cell stress fiber and focal adhesion formation and barrier function. |
2009 |
Biochim. Biophys. Acta |
pmid:19632305
|
Fan Y et al. |
Rottlerin protected dopaminergic cell line from cytotoxicity of 6-hydroxydopamine by inhibiting PKCdelta phosphorylation. |
2009 |
Neurosci Bull |
pmid:19633700
|
Esper RM and Loeb JA |
Neurotrophins induce neuregulin release through protein kinase Cdelta activation. |
2009 |
J. Biol. Chem. |
pmid:19648576
|
Maioli E et al. |
Rottlerin inhibits ROS formation and prevents NFkappaB activation in MCF-7 and HT-29 cells. |
2009 |
J. Biomed. Biotechnol. |
pmid:20168983
|