| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neoplasms, Experimental | D009374 | 10 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
rottlerin
Rottlerin is a lipid of Polyketides (PK) class. Rottlerin is associated with abnormalities such as PARAGANGLIOMAS 2, Hyperostosis, Diffuse Idiopathic Skeletal, Virus Diseases, Perisylvian syndrome and Autoimmune disease (systemic) NOS. The involved functions are known as Apoptosis, Regulation, Signal Transduction, inhibitors and Proteasome Inhibitors [MoA]. Rottlerin often locates in Clone, Membrane, Body tissue, Plasma membrane and soluble. The associated genes with Rottlerin are XIAP gene, GAPDH gene, ICAM1 gene, P4HTM gene and TNFSF10 gene. The related lipids are Promega, Fatty Acids, Sphingolipids, Lipopolysaccharides and Saponin. The related experimental models are Mouse Model, Xenograft Model and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of rottlerin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with rottlerin?
rottlerin is suspected in Infection, Morphologically altered structure, Ischemia, Pulmonary Edema, Asthma, Cardiovascular Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- J. Biol. Chem. (5)
- Am. J. Physiol. Heart Circ. Physiol. (3)
- Am. J. Physiol. Lung Cell Mol. Physiol. (3)
- Others (19)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with rottlerin
PubChem Associated disorders and diseases
What pathways are associated with rottlerin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with rottlerin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Biol. Chem. (9)
- J. Pharmacol. Exp. Ther. (4)
- Am. J. Physiol. Lung Cell Mol. Physiol. (3)
- Others (42)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with rottlerin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with rottlerin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with rottlerin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with rottlerin?
Cancer Model
Cancer Model are used in the study 'Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family.' (Ohno I et al., 2010) and Cancer Model are used in the study 'Rottlerin induces Wnt co-receptor LRP6 degradation and suppresses both Wnt/β-catenin and mTORC1 signaling in prostate and breast cancer cells.' (Lu W et al., 2014).
Mouse Model
Mouse Model are used in the study 'Neuroprotective effect of protein kinase C delta inhibitor rottlerin in cell culture and animal models of Parkinson's disease.' (Zhang D et al., 2007).
Xenograft Model
Xenograft Model are used in the study 'Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family.' (Ohno I et al., 2010).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with rottlerin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shemon AN et al. | Rottlerin inhibits P2X(7) receptor-stimulated phospholipase D activity in chronic lymphocytic leukaemia B-lymphocytes. | 2007 | Immunol. Cell Biol. | pmid:17130901 |
| Chwae YJ et al. | Activation-induced upregulation of inhibitory killer Ig-like receptors is regulated by protein kinase C. | 2007 Apr-May | Immunol. Cell Biol. | pmid:17228322 |
| Ko NY et al. | Interleukin-32α production is regulated by MyD88-dependent and independent pathways in IL-1β-stimulated human alveolar epithelial cells. | 2011 Jan-Feb | Immunobiology | pmid:20430472 |
| Olson ER et al. | Angiotensin II-induced extracellular signal-regulated kinase 1/2 activation is mediated by protein kinase Cdelta and intracellular calcium in adult rat cardiac fibroblasts. | 2008 | Hypertension | pmid:18195168 |
| Zou Y et al. | Contact inhibition causes strong downregulation of expression of MICA in human fibroblasts and decreased NK cell killing. | 2006 | Hum. Immunol. | pmid:16698440 |
| Jiang W et al. | [Role of protein kinase C-delta in hyperthermia-induced apoptosis in tongue squamous cell carcinoma Tca8113 cells]. | 2010 | Hua Xi Kou Qiang Yi Xue Za Zhi | pmid:21179694 |
| Schonhoff CM et al. | Protein kinase Cdelta mediates cyclic adenosine monophosphate-stimulated translocation of sodium taurocholate cotransporting polypeptide and multidrug resistant associated protein 2 in rat hepatocytes. | 2008 | Hepatology | pmid:18273864 |
| Lesage GD et al. | Insulin inhibits secretin-induced ductal secretion by activation of PKC alpha and inhibition of PKA activity. | 2002 | Hepatology | pmid:12198656 |
| Kitamura K et al. | The second phase activation of protein kinase C delta at late G1 is required for DNA synthesis in serum-induced cell cycle progression. | 2003 | Genes Cells | pmid:12653960 |
| Ceni E et al. | Acetaldehyde inhibits PPARgamma via H2O2-mediated c-Abl activation in human hepatic stellate cells. | 2006 | Gastroenterology | pmid:17030193 |
| Niwa K et al. | Roles of protein kinase C delta in the accumulation of P53 and the induction of apoptosis in H2O2-treated bovine endothelial cells. | 2002 | Free Radic. Res. | pmid:12592666 |
| Waki K et al. | Involvement of protein kinase Cdelta in the activation of NADPH oxidase and the phagocytosis of neutrophils. | 2006 | Free Radic. Res. | pmid:16517500 |
| Marengo B et al. | Mechanisms of BSO (L-buthionine-S,R-sulfoximine)-induced cytotoxic effects in neuroblastoma. | 2008 | Free Radic. Biol. Med. | pmid:17991446 |
| Nitti M et al. | Central role of PKCdelta in glycoxidation-dependent apoptosis of human neurons. | 2005 | Free Radic. Biol. Med. | pmid:15749380 |
| Domenicotti C et al. | Role of PKC-delta activity in glutathione-depleted neuroblastoma cells. | 2003 | Free Radic. Biol. Med. | pmid:12927600 |
| Lee CF et al. | Involvement of protein kinase C delta in the alteration of mitochondrial mass in human cells under oxidative stress. | 2006 | Free Radic. Biol. Med. | pmid:16785027 |
| Prast-Nielsen S et al. | Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assay. | 2011 | Free Radic. Biol. Med. | pmid:21262347 |
| Chen RC et al. | Naringin protects against anoxia/reoxygenation-induced apoptosis in H9c2 cells via the Nrf2 signaling pathway. | 2015 | Food Funct | pmid:25773745 |
| Kim IS et al. | Differential CCR1-mediated chemotaxis signaling induced by human CC chemokine HCC-4/CCL16 in HOS cells. | 2005 | FEBS Lett. | pmid:16226254 |
| Meacci E et al. | Permissive role of protein kinase C alpha but not protein kinase C delta in sphingosine 1-phosphate-induced Rho A activation in C2C12 myoblasts. | 2000 | FEBS Lett. | pmid:11018530 |
| Arisaka M et al. | Involvement of protein kinase Cdelta in induction of apoptosis by cationic liposomes in macrophage-like RAW264.7 cells. | 2010 | FEBS Lett. | pmid:20122929 |
| Gschwendt M et al. | Elongation factor-2 kinase: effective inhibition by the novel protein kinase inhibitor rottlerin and relative insensitivity towards staurosporine. | 1994 | FEBS Lett. | pmid:8307162 |
| Keenan C et al. | Isoform specificity of activators and inhibitors of protein kinase C gamma and delta. | 1997 | FEBS Lett. | pmid:9326378 |
| Ahmed S et al. | Protein kinase Ctheta activity is involved in the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced signal transduction pathway leading to apoptosis in L-MAT, a human lymphoblastic T-cell line. | 2005 | FEBS J. | pmid:15691325 |
| Shukla A et al. | Transcriptional up-regulation of MMP12 and MMP13 by asbestos occurs via a PKCdelta-dependent pathway in murine lung. | 2006 | FASEB J. | pmid:16571779 |
| Goldklang MP et al. | Treatment of experimental asthma using a single small molecule with anti-inflammatory and BK channel-activating properties. | 2013 | FASEB J. | pmid:23995289 |
| McNally AK et al. | Foreign body-type multinucleated giant cell formation requires protein kinase C beta, delta, and zeta. | 2008 | Exp. Mol. Pathol. | pmid:18067888 |
| Byun HS et al. | Prevention of TNF-induced necrotic cell death by rottlerin through a Nox1 NADPH oxidase. | 2008 | Exp. Mol. Med. | pmid:18446057 |
| Park EJ and Kwon TK | Rottlerin enhances IL-1β-induced COX-2 expression through sustained p38 MAPK activation in MDA-MB-231 human breast cancer cells. | 2011 | Exp. Mol. Med. | pmid:21971413 |
| Kawabata H et al. | A HAMP promoter bioassay system for identifying chemical compounds that modulate hepcidin expression. | 2015 | Exp. Hematol. | pmid:25633564 |
| Dreixler JC et al. | Protein kinase C subtypes and retinal ischemic preconditioning. | 2008 | Exp. Eye Res. | pmid:18722601 |
| Valacchi G et al. | Rottlerin: a multifaced regulator of keratinocyte cell cycle. | 2009 | Exp. Dermatol. | pmid:19492998 |
| Wang P et al. | Relaxin Inhibits Cardiac Fibrosis in Diabetic Rats: Roles of Protein Kinase Cδ. | 2018 | Exp. Clin. Endocrinol. Diabetes | pmid:28895644 |
| Basu A et al. | Potentiation of tumor necrosis factor-alpha-induced cell death by rottlerin through a cytochrome-C-independent pathway. | 2002 | Exp. Cell Res. | pmid:12169276 |
| Hai CM et al. | Conventional protein kinase C mediates phorbol-dibutyrate-induced cytoskeletal remodeling in a7r5 smooth muscle cells. | 2002 | Exp. Cell Res. | pmid:12372340 |
| Gao FH et al. | Protein kinase C-delta mediates down-regulation of heterogeneous nuclear ribonucleoprotein K protein: involvement in apoptosis induction. | 2009 | Exp. Cell Res. | pmid:19747914 |
| Matsuoka H et al. | Tamoxifen inhibits tumor cell invasion and metastasis in mouse melanoma through suppression of PKC/MEK/ERK and PKC/PI3K/Akt pathways. | 2009 | Exp. Cell Res. | pmid:19393235 |
| Shimamura K et al. | Expression of adhesion molecules by sphingosine 1-phosphate and histamine in endothelial cells. | 2004 | Eur. J. Pharmacol. | pmid:14975703 |
| Tepperman BL et al. | Effect of protein kinase C activation on intracellular Ca2+ signaling and integrity of intestinal epithelial cells. | 2005 | Eur. J. Pharmacol. | pmid:16005455 |
| Samokhin GP et al. | Effects of protein kinase C inhibitors on thromboxane production by thrombin-stimulated platelets. | 1999 | Eur. J. Pharmacol. | pmid:10618482 |
| Leppänen T et al. | Inhibition of protein kinase Cdelta reduces tristetraprolin expression by destabilizing its mRNA in activated macrophages. | 2010 | Eur. J. Pharmacol. | pmid:19925787 |
| Brutkiewicz RR et al. | Protein kinase C delta is a critical regulator of CD1d-mediated antigen presentation. | 2007 | Eur. J. Immunol. | pmid:17705133 |
| Lin W et al. | Induction of cell cycle arrest by the carbazole alkaloid Clauszoline-I from Clausena vestita D. D. Tao via inhibition of the PKCδ phosphorylation. | 2012 | Eur J Med Chem | pmid:22093759 |
| Lin CC et al. | Establishment of a melanogenesis regulation assay system using a fluorescent protein reporter combined with the promoters for the melanogenesis-related genes in human melanoma cells. | 2015 | Enzyme Microb. Technol. | pmid:25435499 |
| Lawal AO and Ellis EM | Nrf2-mediated adaptive response to cadmium-induced toxicity involves protein kinase C delta in human 1321N1 astrocytoma cells. | 2011 | Environ. Toxicol. Pharmacol. | pmid:21787730 |
| Morino K et al. | Insulin-induced c-Jun N-terminal kinase activation is negatively regulated by protein kinase C delta. | 2001 | Endocrinology | pmid:11356718 |
| Kayali AG et al. | Rottlerin inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes by uncoupling mitochondrial oxidative phosphorylation. | 2002 | Endocrinology | pmid:12239100 |
| Bureik M et al. | Modulation of steroid hydroxylase activity in stably transfected V79MZh11B1 and V79MZh11B2 cells by PKC and PKD inhibitors. | 2002 | Endocr. Res. | pmid:12530636 |
| Chen Z et al. | Protein kinase Cδ inactivation inhibits cellular proliferation and decreases survival in human neuroendocrine tumors. | 2011 | Endocr. Relat. Cancer | pmid:21990324 |
| Mertens-Walker I et al. | Gonadotropin-induced ovarian cancer cell migration and proliferation require extracellular signal-regulated kinase 1/2 activation regulated by calcium and protein kinase C{delta}. | 2010 | Endocr. Relat. Cancer | pmid:20215102 |
| Zhang X et al. | NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels. | 2005 | EMBO J. | pmid:16319926 |
| Huang SP et al. | Ethambutol induces impaired autophagic flux and apoptosis in the rat retina. | 2015 | Dis Model Mech | pmid:26092127 |
| Wallerstedt E et al. | Protein kinase C-delta is involved in the inflammatory effect of IL-6 in mouse adipose cells. | 2010 | Diabetologia | pmid:20151299 |
| Ducroc R et al. | Luminal leptin induces rapid inhibition of active intestinal absorption of glucose mediated by sodium-glucose cotransporter 1. | 2005 | Diabetes | pmid:15677491 |
| Ross R et al. | Hypothalamic protein kinase C regulates glucose production. | 2008 | Diabetes | pmid:18511848 |
| Kim YH et al. | Protein kinase C-delta mediates neuronal apoptosis in the retinas of diabetic rats via the Akt signaling pathway. | 2008 | Diabetes | pmid:18443201 |
| Hagelkruys A et al. | A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog. | 2014 | Development | pmid:24449838 |
| Lee NR et al. | Cytokine secreted by S100A9 via TLR4 in monocytes delays neutrophil apoptosis by inhibition of caspase 9/3 pathway. | 2016 | Cytokine | pmid:27459393 |
| Lee JS et al. | House dust mite, Dermatophagoides pteronissinus increases expression of MCP-1, IL-6, and IL-8 in human monocytic THP-1 cells. | 2008 | Cytokine | pmid:18490175 |
| Furuya T et al. | Role of retinal glial cell glutamate transporters in retinal ganglion cell survival following stimulation of NMDA receptor. | 2012 | Curr. Eye Res. | pmid:22335803 |
| Bull ND et al. | Protein kinase C-mediated modulation of glutamate transporter activity in rat retina. | 2007 | Curr. Eye Res. | pmid:17364745 |
| Maioli E and Valacchi G | Rottlerin: bases for a possible usage in psoriasis. | 2010 | Curr. Drug Metab. | pmid:20540694 |
| Dang DK et al. | Inhibition of protein kinase (PK) Cδ attenuates methamphetamine-induced dopaminergic toxicity via upregulation of phosphorylation of tyrosine hydroxylase at Ser40 by modulation of protein phosphatase 2A and PKA. | 2015 | Clin. Exp. Pharmacol. Physiol. | pmid:25400014 |
| Xie MJ et al. | Evidence that apoptotic signalling in hypertrophic cardiomyocytes is determined by mitochondrial pathways involving protein kinase Cδ. | 2010 | Clin. Exp. Pharmacol. Physiol. | pmid:20880184 |
| Clements RT et al. | Rottlerin increases cardiac contractile performance and coronary perfusion through BKCa++ channel activation after cold cardioplegic arrest in isolated hearts. | 2011 | Circulation | pmid:21911819 |
| Sussmann M et al. | Induction of hyaluronic acid synthase 2 (HAS2) in human vascular smooth muscle cells by vasodilatory prostaglandins. | 2004 | Circ. Res. | pmid:14752026 |
| Lee HG and Yang JH | PKC-δ mediates TCDD-induced apoptosis of chondrocyte in ROS-dependent manner. | 2010 | Chemosphere | pmid:20846705 |
| Maddox JF et al. | Allyl alcohol activation of protein kinase C delta leads to cytotoxicity of rat hepatocytes. | 2003 | Chem. Res. Toxicol. | pmid:12755590 |
| Leverence JT et al. | Lipopolysaccharide-induced cytokine expression in alveolar epithelial cells: role of PKCζ-mediated p47phox phosphorylation. | 2011 | Chem. Biol. Interact. | pmid:20920494 |
| Lim JH et al. | Rottlerin induces apoptosis of HT29 colon carcinoma cells through NAG-1 upregulation via an ERK and p38 MAPK-dependent and PKC δ-independent mechanism. | 2012 | Chem. Biol. Interact. | pmid:22410117 |
| Mai HN et al. | Protein kinase Cδ knockout mice are protected from cocaine-induced hepatotoxicity. | 2019 | Chem. Biol. Interact. | pmid:30393195 |
| Valacchi G et al. | Rottlerin exhibits antiangiogenic effects in vitro. | 2011 | Chem Biol Drug Des | pmid:21435184 |
| Goon Goh F et al. | G-protein-dependent and -independent pathways regulate proteinase-activated receptor-2 mediated p65 NFkappaB serine 536 phosphorylation in human keratinocytes. | 2008 | Cell. Signal. | pmid:18424071 |
| Zhao Y et al. | Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin. | 2007 | Cell. Signal. | pmid:17689924 |
| Lewis AE et al. | Protein kinase C delta is not activated by caspase-3 and its inhibition is sufficient to induce apoptosis in the colon cancer line, COLO 205. | 2005 | Cell. Signal. | pmid:15494216 |
| Deszo EL et al. | IL-4-dependent CD86 expression requires JAK/STAT6 activation and is negatively regulated by PKCdelta. | 2004 | Cell. Signal. | pmid:14636897 |
| Lu W et al. | Rottlerin induces Wnt co-receptor LRP6 degradation and suppresses both Wnt/β-catenin and mTORC1 signaling in prostate and breast cancer cells. | 2014 | Cell. Signal. | pmid:24607787 |
| Bierhals K et al. | The epsilon-isoform of PKC mediates the hypertonic activation of cation channels in confluent monolayers of rat hepatocytes. | 2007 | Cell. Physiol. Biochem. | pmid:17762167 |
| Matschke V et al. | The Natural Plant Product Rottlerin Activates Kv7.1/KCNE1 Channels. | 2016 | Cell. Physiol. Biochem. | pmid:27997884 |
| Mischitelli M et al. | Stimulation of Suicidal Erythrocyte Death by Rottlerin. | 2016 | Cell. Physiol. Biochem. | pmid:27889758 |
| Chen RX et al. | Neuromedin S increases L-type Ca(2+) channel currents through G(i)α-protein and phospholipase C-dependent novel protein kinase C delta pathway in adult rat ventricular myocytes. | 2012 | Cell. Physiol. Biochem. | pmid:22832358 |
| Okuwa H et al. | Sphingosine suppresses mesothelioma cell proliferation by inhibiting PKC-δ and inducing cell cycle arrest at the G(0)/G(1) phase. | 2012 | Cell. Physiol. Biochem. | pmid:23221613 |
| Shumilina E et al. | Phosphoinositide-dependent kinase PDK1 in the regulation of Ca2+ entry into mast cells. | 2010 | Cell. Physiol. Biochem. | pmid:21063107 |
| Song BW et al. | Protein kinase C activation stimulates mesenchymal stem cell adhesion through activation of focal adhesion kinase. | 2013 | Cell Transplant | pmid:23006313 |
| Mok SA et al. | A retrograde apoptotic signal originating in NGF-deprived distal axons of rat sympathetic neurons in compartmented cultures. | 2009 | Cell Res. | pmid:19188931 |
| Lee YJ et al. | Protein kinase Cdelta overexpression enhances radiation sensitivity via extracellular regulated protein kinase 1/2 activation, abolishing the radiation-induced G(2)-M arrest. | 2002 | Cell Growth Differ. | pmid:12065247 |
| Parmer TG et al. | Effects of rottlerin, an inhibitor of calmodulin-dependent protein kinase III, on cellular proliferation, viability, and cell cycle distribution in malignant glioma cells. | 1997 | Cell Growth Differ. | pmid:9056675 |
| Hasima N and Ozpolat B | Regulation of autophagy by polyphenolic compounds as a potential therapeutic strategy for cancer. | 2014 | Cell Death Dis | pmid:25375374 |
| Basu A et al. | Involvement of protein kinase C-delta in DNA damage-induced apoptosis. | 2001 | Cell Death Differ. | pmid:11526445 |
| Nakatake M et al. | STAT3 and PKC differentially regulate telomerase activity during megakaryocytic differentiation of K562 cells. | 2007 | Cell Cycle | pmid:17525530 |
| Kim YR et al. | Apoptosis signal-regulating kinase1 is inducible by protein kinase Cδ and contributes to phorbol ester-mediated G1 phase arrest through persistent JNK activation. | 2011 | Cell Biochem. Biophys. | pmid:21468691 |
| Szilagyi K et al. | PKCδ is dispensible for oxLDL uptake and foam cell formation by human and murine macrophages. | 2014 | Cardiovasc. Res. | pmid:25253077 |
| Skaletz-Rorowski A et al. | PKC delta-induced activation of MAPK pathway is required for bFGF-stimulated proliferation of coronary smooth muscle cells. | 2005 | Cardiovasc. Res. | pmid:15949478 |
| Zatta AJ et al. | Infarct-sparing effect of myocardial postconditioning is dependent on protein kinase C signalling. | 2006 | Cardiovasc. Res. | pmid:16443207 |
| Schreckenberg R et al. | Inhibition of Ca2+-dependent PKC isoforms unmasks ERK-dependent hypertrophic growth evoked by phenylephrine in adult ventricular cardiomyocytes. | 2004 | Cardiovasc. Res. | pmid:15276481 |
| Lin CW et al. | Quercetin inhibition of tumor invasion via suppressing PKC delta/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells. | 2008 | Carcinogenesis | pmid:18628248 |
| Lim JH et al. | Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC delta-independent mechanism in human malignant tumor cells. | 2009 | Carcinogenesis | pmid:19037087 |
| Park SK et al. | Kalopanaxsaponin A inhibits PMA-induced invasion by reducing matrix metalloproteinase-9 via PI3K/Akt- and PKCdelta-mediated signaling in MCF-7 human breast cancer cells. | 2009 | Carcinogenesis | pmid:19420016 |
| Shen SM et al. | Downregulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells. | 2010 | Carcinogenesis | pmid:20015864 |
| Lim SC et al. | Lipid raft-dependent death receptor 5 (DR5) expression and activation are critical for ursodeoxycholic acid-induced apoptosis in gastric cancer cells. | 2011 | Carcinogenesis | pmid:21362627 |