Lucidone

Lucidone is a lipid of Polyketides (PK) class. Lucidone is associated with abnormalities such as and Infection. The involved functions are known as Protein Biosynthesis, Metabolic Inhibition, protease activity, luciferase activity and protein expression. Lucidone often locates in Protoplasm and Cell-Free System. The associated genes with Lucidone are HMOX1 gene, OAS1 gene, OAS2 gene, OAS3 gene and ALPP gene. The related lipids are Lipopolysaccharides and Promega.

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Introduction

To understand associated biological information of Lucidone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lucidone?

Lucidone is suspected in Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lucidone

PubChem Associated disorders and diseases

What pathways are associated with Lucidone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lucidone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lucidone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lucidone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Lucidone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lucidone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Lucidone

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Authors Title Published Journal PubMed Link
Chen WC et al. Lucidone suppresses dengue viral replication through the induction of heme oxygenase-1. 2018 Virulence pmid:29338543
Yang HL et al. Lucidone Promotes the Cutaneous Wound Healing Process via Activation of the PIK/AKT, Wnt/β-catenin and NF-κB Signaling Pathways. 2017 Biochim Biophys Acta Mol Cell Res pmid:27816443
Chen WC et al. Lucidone suppresses hepatitis C virus replication by Nrf2-mediated heme oxygenase-1 induction. 2013 Antimicrob. Agents Chemother. pmid:23254429
Hsieh YH and Wang SY Lucidone from Lindera erythrocarpa Makino fruits suppresses adipogenesis in 3T3-L1 cells and attenuates obesity and consequent metabolic disorders in high-fat diet C57BL/6 mice. 2013 Phytomedicine pmid:23265843
Kumar KJ et al. Lucidone protects human skin keratinocytes against free radical-induced oxidative damage and inflammation through the up-regulation of HO-1/Nrf2 antioxidant genes and down-regulation of NF-κB signaling pathway. 2013 Food Chem. Toxicol. pmid:23712098
Senthil Kumar KJ et al. Hepatoprotective effect of lucidone against alcohol-induced oxidative stress in human hepatic HepG2 cells through the up-regulation of HO-1/Nrf-2 antioxidant genes. 2012 Toxicol In Vitro pmid:22484158
Kumar KJ et al. Lucidone, a novel melanin inhibitor from the fruit of Lindera erythrocarpa Makino. 2010 Phytother Res pmid:20077436
Senthil Kumar KJ et al. Anti-inflammatory effect of lucidone in mice via inhibition of NF-kappaB/MAP kinase pathway. 2010 Int. Immunopharmacol. pmid:20079881
Senthil Kumar KJ and Wang SY Lucidone inhibits iNOS and COX-2 expression in LPS-induced RAW 264.7 murine macrophage cells via NF-kappaB and MAPKs signaling pathways. 2009 Planta Med. pmid:19194838
Wang SY et al. Antiinflammatory activity of Lindera erythrocarpa fruits. 2008 Phytother Res pmid:17726736