butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Acidosis D000138 13 associated lipids
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Alzheimer Disease D000544 76 associated lipids
Anaplasia D000708 1 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Angina Pectoris D000787 27 associated lipids
Aphakia, Postcataract D001036 1 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Astigmatism D001251 1 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Foote AP and Freetly HC Effect of abomasal butyrate infusion on net nutrient flux across the portal-drained viscera and liver of growing lambs. 2016 J. Anim. Sci. pmid:27482683
Terova G et al. Effects of Sodium Butyrate Treatment on Histone Modifications and the Expression of Genes Related to Epigenetic Regulatory Mechanisms and Immune Response in European Sea Bass (Dicentrarchus Labrax) Fed a Plant-Based Diet. 2016 PLoS ONE pmid:27471849
Jawed K et al. Engineered Production of Short Chain Fatty Acid in Escherichia coli Using Fatty Acid Synthesis Pathway. 2016 PLoS ONE pmid:27466817
Gargari G et al. Consumption of a Bifidobacterium bifidum Strain for 4 Weeks Modulates Dominant Intestinal Bacterial Taxa and Fecal Butyrate in Healthy Adults. 2016 Appl. Environ. Microbiol. pmid:27451450
Teixeira C et al. Effects of variety and steeping conditions on some barley components associated with colonic health. 2016 J. Sci. Food Agric. pmid:27450418
Zhou J et al. Maternal sodium butyrate supplement elevates the lipolysis in adipose tissue and leads to lipid accumulation in offspring liver of weaning-age rats. 2016 Lipids Health Dis pmid:27449927
Astakhova L et al. Short Chain Fatty Acids (SCFA) Reprogram Gene Expression in Human Malignant Epithelial and Lymphoid Cells. 2016 PLoS ONE pmid:27441625
Bai G et al. Dietary Casein and Soy Protein Isolate Modulate the Effects of Raffinose and Fructooligosaccharides on the Composition and Fermentation of Gut Microbiota in Rats. 2016 J. Food Sci. pmid:27434756
Hou G et al. Tetracycline removal and effect on the formation and degradation of extracellular polymeric substances and volatile fatty acids in the process of hydrogen fermentation. 2016 Bioresour. Technol. pmid:27070285
Reijnders D et al. Effects of Gut Microbiota Manipulation by Antibiotics on Host Metabolism in Obese Humans: A Randomized Double-Blind Placebo-Controlled Trial. 2016 Cell Metab. pmid:27411009
Longpré J et al. Impact of mash feeding versus pellets on propionic/butyric acid levels and on total load in the gastrointestinal tract of growing pigs. 2016 J. Anim. Sci. pmid:27065267
Early JV et al. Oxadiazoles Have Butyrate-Specific Conditional Activity against Mycobacterium tuberculosis. 2016 Antimicrob. Agents Chemother. pmid:27044545
He B et al. Effects of sodium butyrate supplementation on reproductive performance and colostrum composition in gilts. 2016 Animal pmid:27040131
Petry FS et al. Histone deacetylase inhibition prevents the impairing effects of hippocampal gastrin-releasing peptide receptor antagonism on memory consolidation and extinction. 2016 Behav. Brain Res. pmid:27025446
Frycz BA et al. Transcript level of AKR1C3 is down-regulated in gastric cancer. 2016 Biochem. Cell Biol. pmid:27019068
Li H et al. Sodium butyrate exerts neuroprotective effects by restoring the blood-brain barrier in traumatic brain injury mice. 2016 Brain Res. pmid:27017959
Ortega JF et al. Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein. 2016 Oncotarget pmid:27013579
Sjöblom M et al. Catalytic upgrading of butyric acid towards fine chemicals and biofuels. 2016 FEMS Microbiol. Lett. pmid:26994015
Zhao Z et al. Potential enhancement of direct interspecies electron transfer for syntrophic metabolism of propionate and butyrate with biochar in up-flow anaerobic sludge blanket reactors. 2016 Bioresour. Technol. pmid:26967338
Sun J et al. Antidepressant-like effects of sodium butyrate and its possible mechanisms of action in mice exposed to chronic unpredictable mild stress. 2016 Neurosci. Lett. pmid:26957230
Su CL et al. Epigenetic regulation of BDNF in the learned helplessness-induced animal model of depression. 2016 J Psychiatr Res pmid:26921875
Tanaka S et al. Relationship of Enhanced Butyrate Production by Colonic Butyrate-Producing Bacteria to Immunomodulatory Effects in Normal Mice Fed an Insoluble Fraction of Brassica rapa L. 2016 Appl. Environ. Microbiol. pmid:26921420
Ng CH and Yang KL Lipase in biphasic alginate beads as a biocatalyst for esterification of butyric acid and butanol in aqueous media. 2016 Enzyme Microb. Technol. pmid:26672465
Han A et al. Cellular Metabolism and Dose Reveal Carnitine-Dependent and -Independent Mechanisms of Butyrate Oxidation in Colorectal Cancer Cells. 2016 J. Cell. Physiol. pmid:26661480
Tiwari P et al. Preventive effects of butyric acid, nicotinamide, calcium glucarate alone or in combination during the 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis via modulation of K-Ras-PI3K-AKTpathway and associated micro RNAs. 2016 Biochimie pmid:26655363
Valvassori SS et al. Sodium butyrate has an antimanic effect and protects the brain against oxidative stress in an animal model of mania induced by ouabain. 2016 Psychiatry Res pmid:26654753
Mátis G et al. Feed-drug interaction of orally applied butyrate and phenobarbital on hepatic cytochrome P450 activity in chickens. 2016 J Anim Physiol Anim Nutr (Berl) pmid:26614344
Luceri C et al. Effect of butyrate enemas on gene expression profiles and endoscopic/histopathological scores of diverted colorectal mucosa: A randomized trial. 2016 Dig Liver Dis pmid:26607831
Kratsman N et al. Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model. 2016 Neuropharmacology pmid:26577018
Heidor R et al. The chemopreventive activity of butyrate-containing structured lipids in experimental rat hepatocarcinogenesis. 2016 Mol Nutr Food Res pmid:26548572
Junicke H et al. Kinetic and thermodynamic control of butyrate conversion in non-defined methanogenic communities. 2016 Appl. Microbiol. Biotechnol. pmid:26403924
Ayers LW et al. Changes in dam and pup behavior following repeated postnatal exposure to a predator odor (TMT): A preliminary investigation in Long-Evans rats. 2016 Dev Psychobiol pmid:26394891
Contreras-Leal E et al. Histone deacetylase inhibitors promote the expression of ATP2A3 gene in breast cancer cell lines. 2016 Mol. Carcinog. pmid:26331238
Russo R et al. Sodium butyrate and its synthetic amide derivative modulate nociceptive behaviors in mice. 2016 Pharmacol. Res. pmid:26675718
Reddy YS et al. Study on Synthesis, Characterization and Antiproliferative Activity of Novel Diisopropylphenyl Esters of Selected Fatty Acids. 2016 J Oleo Sci pmid:26666272
Polycarpo GV et al. Effects of lipid sources, lysophospholipids and organic acids in maize-based broiler diets on nutrient balance, liver concentration of fat-soluble vitamins, jejunal microbiota and performance. 2016 Br. Poult. Sci. pmid:27494540
Kim M et al. Butyric acid production from softwood hydrolysate by acetate-consuming Clostridium sp. S1 with high butyric acid yield and selectivity. 2016 Bioresour. Technol. pmid:27474955
Xing X et al. Sodium butyrate protects against oxidative stress in HepG2 cells through modulating Nrf2 pathway and mitochondrial function. 2016 J. Physiol. Biochem. pmid:28600747
Huang H et al. Regulation of TWIK-related potassium channel-1 (Trek1) restitutes intestinal epithelial barrier function. 2016 Cell. Mol. Immunol. pmid:25683610
Bastiaansen JA et al. Measuring changes in substrate utilization in the myocardium in response to fasting using hyperpolarized [1-(13)C]butyrate and [1-(13)C]pyruvate. 2016 Sci Rep pmid:27150735
Seki K et al. Varying butyric acid amounts induce different stress- and cell death-related signals in nerve growth factor-treated PC12 cells: implications in neuropathic pain absence during periodontal disease progression. 2016 Apoptosis pmid:26994613
Zhang T et al. Sodium Butyrate Reduces Colitogenic Immunoglobulin A-Coated Bacteria and Modifies the Composition of Microbiota in IL-10 Deficient Mice. 2016 Nutrients pmid:27886121
Tochio T et al. An Alteration in the Cecal Microbiota Composition by Feeding of 1-Kestose Results in a Marked Increase in the Cecal Butyrate Content in Rats. 2016 PLoS ONE pmid:27861621
Tian H et al. Discovery of a Flexible Triazolylbutanoic Acid as a Highly Potent Uric Acid Transporter 1 (URAT1) Inhibitor. 2016 Molecules pmid:27854343
Neis EP et al. Effects of Liver Resection on Hepatic Short-Chain Fatty Acid Metabolism in Humans. 2016 PLoS ONE pmid:27835668
Khairy H et al. The NADH:flavin oxidoreductase Nox from Rhodococcus erythropolis MI2 is the key enzyme of 4,4'-dithiodibutyric acid degradation. 2016 Lett. Appl. Microbiol. pmid:27564089
Kong X et al. Inhibiting excessive acidification using zero-valent iron in anaerobic digestion of food waste at high organic load rates. 2016 Bioresour. Technol. pmid:26998799
Bencsik R et al. Improved transgene expression in doxycycline-inducible embryonic stem cells by repeated chemical selection or cell sorting. 2016 Stem Cell Res pmid:27591479
Han R et al. Sodium Butyrate Upregulates miR-203 Expression to Exert Anti-Proliferation Effect on Colorectal Cancer Cells. 2016 Cell. Physiol. Biochem. pmid:27771718
Polak U et al. Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming. 2016 Stem Cells Dev. pmid:27615158