butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Chang G et al. | Dietary Sodium Butyrate Supplementation Reduces High-Concentrate Diet Feeding-Induced Apoptosis in Mammary Cells in Dairy Goats. | 2018 | J. Agric. Food Chem. | pmid:29446933 |
Hidaka M et al. | Three lysophosphatidic acids with a distinct long chain moiety differently affect cell differentiation of human colon epithelial cells to goblet cells. | 2018 | Life Sci. | pmid:29412173 |
da Silva JS et al. | Nutritive value and fermentation quality of palisadegrass and stylo mixed silages. | 2018 | Anim. Sci. J. | pmid:28905506 |
Johnson J et al. | Valproate and sodium butyrate attenuate manganese-decreased locomotor activity and astrocytic glutamate transporters expression in mice. | 2018 | Neurotoxicology | pmid:28610743 |
Zhu J et al. | Sodium butyrate modulates a methamphetamine-induced conditioned place preference. | 2017 | J. Neurosci. Res. | pmid:27426635 |
Liangzhan S et al. | Effect of substitution of oat hulls for traditional fiber source on digestion and performance of fattening rabbits. | 2017 | Animal | pmid:27821223 |
Sasajima H et al. | Intranasal Administration of Rotenone to Mice Induces Dopaminergic Neurite Degeneration of Dopaminergic Neurons in the Substantia Nigra. | 2017 | Biol. Pharm. Bull. | pmid:28049942 |
Kurano M et al. | Involvement of Band3 in the efflux of sphingosine 1-phosphate from erythrocytes. | 2017 | PLoS ONE | pmid:28494002 |
Du H et al. | Exploring the microbial origins of p-cresol and its co-occurrence pattern in the Chinese liquor-making process. | 2017 | Int. J. Food Microbiol. | pmid:28843121 |
Wu T et al. | Anthocyanins in black rice, soybean and purple corn increase fecal butyric acid and prevent liver inflammation in high fat diet-induced obese mice. | 2017 | Food Funct | pmid:28792056 |
Berni Canani R et al. | Specific Signatures of the Gut Microbiota and Increased Levels of Butyrate in Children Treated with Fermented Cow's Milk Containing Heat-Killed Lactobacillus paracasei CBA L74. | 2017 | Appl. Environ. Microbiol. | pmid:28733284 |
Pelgrim CE et al. | Butyrate Reduces HFD-Induced Adipocyte Hypertrophy and Metabolic Risk Factors in Obese LDLr-/-.Leiden Mice. | 2017 | Nutrients | pmid:28686216 |
Tsung AJ et al. | Methylation regulates HEY1 expression in glioblastoma. | 2017 | Oncotarget | pmid:28574840 |
Wang L et al. | Sodium butyrate suppresses angiotensin II-induced hypertension by inhibition of renal (pro)renin receptor and intrarenal renin-angiotensin system. | 2017 | J. Hypertens. | pmid:28509726 |
Dou X et al. | Sodium butyrate improves porcine host defense peptide expression and relieves the inflammatory response upon Toll-like receptor 2 activation and histone deacetylase inhibition in porcine kidney cells. | 2017 | Oncotarget | pmid:28460447 |
Pant K et al. | Butyrate induces ROS-mediated apoptosis by modulating miR-22/SIRT-1 pathway in hepatic cancer cells. | 2017 | Redox Biol | pmid:28288414 |
Niwińska B et al. | Review: Exogenous butyrate: implications for the functional development of ruminal epithelium and calf performance. | 2017 | Animal | pmid:28193308 |
Jaworska J et al. | The potential neuroprotective role of a histone deacetylase inhibitor, sodium butyrate, after neonatal hypoxia-ischemia. | 2017 | J Neuroinflammation | pmid:28187734 |
Qiu Y et al. | Effect of sodium butyrate on cell proliferation and cell cycle in porcine intestinal epithelial (IPEC-J2) cells. | 2017 | In Vitro Cell. Dev. Biol. Anim. | pmid:28127702 |
Li P et al. | Effect of grape pomace on fermentation quality and aerobic stability of sweet sorghum silage. | 2017 | Anim. Sci. J. | pmid:28485116 |
Yan H and Ajuwon KM | Butyrate modifies intestinal barrier function in IPEC-J2 cells through a selective upregulation of tight junction proteins and activation of the Akt signaling pathway. | 2017 | PLoS ONE | pmid:28654658 |
Batlle-Vilanova P et al. | Microbial electrosynthesis of butyrate from carbon dioxide: Production and extraction. | 2017 | Bioelectrochemistry | pmid:28633067 |
Asquith M et al. | Intestinal Metabolites Are Profoundly Altered in the Context of HLA-B27 Expression and Functionally Modulate Disease in a Rat Model of Spondyloarthritis. | 2017 | pmid:28622455 | |
Lucchetti D et al. | Differentiation Affects the Release of Exosomes from Colon Cancer Cells and Their Ability to Modulate the Behavior of Recipient Cells. | 2017 | Am. J. Pathol. | pmid:28619275 |
Lu N et al. | Butyric acid regulates progesterone and estradiol secretion via cAMP signaling pathway in porcine granulosa cells. | 2017 | J. Steroid Biochem. Mol. Biol. | pmid:28602959 |
Kumar P et al. | Inhibition of HDAC enhances STAT acetylation, blocks NF-κB, and suppresses the renal inflammation and fibrosis in haplotype male mice. | 2017 | Am. J. Physiol. Renal Physiol. | pmid:28566502 |
Tian L et al. | Sodium butyrate improved intestinal immune function associated with NF-κB and p38MAPK signalling pathways in young grass carp (Ctenopharyngodon idella). | 2017 | Fish Shellfish Immunol. | pmid:28546021 |
Wu Q et al. | Insights from the complete genome sequence of Clostridium tyrobutyricum provide a platform for biotechnological and industrial applications. | 2017 | J. Ind. Microbiol. Biotechnol. | pmid:28536840 |
Kihara T et al. | Bacillus cereus-type polyhydroxyalkanoate biosynthetic gene cluster contains R-specific enoyl-CoA hydratase gene. | 2017 | Biosci. Biotechnol. Biochem. | pmid:28532241 |
Payandeh S et al. | Probiotic supplementation effects on milk fatty acid profile in ewes. | 2017 | J. Dairy Res. | pmid:28524013 |
Donovan JD et al. | In Vitro Digestion and Fermentation of Microencapsulated Tributyrin for the Delivery of Butyrate. | 2017 | J. Food Sci. | pmid:28485486 |
Zhou Z et al. | Changes of cecal microflora in chickens following Eimeria tenella challenge and regulating effect of coated sodium butyrate. | 2017 | Exp. Parasitol. | pmid:28455119 |
Yoo M et al. | Metabolic flexibility of a butyrate pathway mutant of Clostridium acetobutylicum. | 2017 | Metab. Eng. | pmid:28159643 |
Chen C et al. | Use of Acetate, Propionate, and Butyrate for Reduction of Nitrate and Sulfate and Methanogenesis in Microcosms and Bioreactors Simulating an Oil Reservoir. | 2017 | Appl. Environ. Microbiol. | pmid:28130297 |
Zhang L et al. | Sodium Butyrate Protects -Against High Fat Diet-Induced Cardiac Dysfunction and Metabolic Disorders in Type II Diabetic Mice. | 2017 | J. Cell. Biochem. | pmid:28109123 |
Cueno ME et al. | Periodontal disease level-butyric acid putatively contributes to the ageing blood: A proposed link between periodontal diseases and the ageing process. | 2017 | Mech. Ageing Dev. | pmid:28108180 |
Zhou D et al. | Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier. | 2017 | World J. Gastroenterol. | pmid:28104981 |
Huang JC et al. | [Protective effect of histone acetylation against cortical injury in neonatal rats]. | 2017 | Zhongguo Dang Dai Er Ke Za Zhi | pmid:28100329 |
Albuquerque Filho MO et al. | Dual influences of early-life maternal deprivation on histone deacetylase activity and recognition memory in rats. | 2017 | Neuroscience | pmid:28089578 |
Kataoka N et al. | Butyrate production under aerobic growth conditions by engineered Escherichia coli. | 2017 | J. Biosci. Bioeng. | pmid:28089378 |
Hichino A et al. | Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells. | 2017 | J. Biol. Chem. | pmid:28057758 |
Fu H et al. | Metabolic engineering of Clostridium tyrobutyricum for enhanced butyric acid production from glucose and xylose. | 2017 | Metab. Eng. | pmid:28040464 |
Jin X et al. | TXNIP mediates the differential responses of A549 cells to sodium butyrate and sodium 4-phenylbutyrate treatment. | 2017 | Cancer Med | pmid:28033672 |
Dai H et al. | Sodium Butyrate Ameliorates High-Concentrate Diet-Induced Inflammation in the Rumen Epithelium of Dairy Goats. | 2017 | J. Agric. Food Chem. | pmid:28032994 |
Moens F et al. | Lactate- and acetate-based cross-feeding interactions between selected strains of lactobacilli, bifidobacteria and colon bacteria in the presence of inulin-type fructans. | 2017 | Int. J. Food Microbiol. | pmid:27810444 |
Dong W et al. | Sodium butyrate activates NRF2 to ameliorate diabetic nephropathy possibly via inhibition of HDAC. | 2017 | J. Endocrinol. | pmid:27799462 |
Zhang K et al. | Regulation of the Docosapentaenoic Acid/Docosahexaenoic Acid Ratio (DPA/DHA Ratio) in Schizochytrium limacinum B4D1. | 2017 | Appl. Biochem. Biotechnol. | pmid:27832512 |
Wang YQ et al. | Enhancement of acetate productivity in a thermophilic (55 °C) hollow-fiber membrane biofilm reactor with mixed culture syngas (H/CO) fermentation. | 2017 | Appl. Microbiol. Biotechnol. | pmid:28110397 |
Chriett S et al. | The histone deacetylase inhibitor sodium butyrate improves insulin signalling in palmitate-induced insulin resistance in L6 rat muscle cells through epigenetically-mediated up-regulation of Irs1. | 2017 | Mol. Cell. Endocrinol. | pmid:27619406 |
Kumar G et al. | Microbial responses to various process disturbances in a continuous hydrogen reactor fed with galactose. | 2017 | J. Biosci. Bioeng. | pmid:27614820 |