butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Prostatic Neoplasms, Castration-Resistant D064129 3 associated lipids
Urea Cycle Disorders, Inborn D056806 2 associated lipids
Acute Lung Injury D055371 33 associated lipids
Diverticulosis, Colonic D043963 1 associated lipids
Genomic Instability D042822 7 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Epstein-Barr Virus Infections D020031 3 associated lipids
Retinal Neoplasms D019572 3 associated lipids
Pouchitis D019449 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Authors Title Published Journal PubMed Link
Gruchlik A et al. Influence of troglitazone, sodium butyrate, 5-aminosalicylic acid and BAY 11-7082 on the chemokine ENA-78/CXCL5 secretion in the intestinal subepithelial myofibroblasts. Acta Pol Pharm pmid:21229889
González-Pajuelo M et al. Metabolic engineering of Clostridium acetobutylicum for the industrial production of 1,3-propanediol from glycerol. Metab. Eng. pmid:16095939
Kien CL et al. Effects of the in vivo supply of butyrate on histone acetylation of cecum in piglets. JPEN J Parenter Enteral Nutr pmid:18165447
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Doble MA et al. Luminal regulation of Na(+)/H(+) exchanger gene expression in rat ileal mucosa. J. Gastrointest. Surg. pmid:12022991
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Varel VH et al. Manure odor potential and Escherichia coli concentrations in manure slurries of feedlot steers fed 40% corn wet distillers grains. J. Environ. Qual. pmid:20830936
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Jung JW et al. Augmentation of sodium butyrate-induced apoptosis by p38 MAP kinase inhibition in rat liver epithelial cells. Antioxid. Redox Signal. pmid:16356138
Liamleam W and Annachhatre AP Electron donors for biological sulfate reduction. Biotechnol. Adv. pmid:17572039
Miki Y et al. Butyrate inhibits oral cancer cell proliferation and regulates expression of secretory phospholipase A2-X and COX-2. Anticancer Res. pmid:17595767
Rahman M et al. The fat-1 transgene in mice increases antioxidant potential, reduces pro-inflammatory cytokine levels, and enhances PPAR-gamma and SIRT-1 expression on a calorie restricted diet. Oxid Med Cell Longev pmid:20716918
Shahbazfar AA et al. A survey on anticancer effects of artemisinin, iron, miconazole, and butyric acid on 5637 (bladder cancer) and 4T1 (Breast cancer) cell lines. J Cancer Res Ther pmid:25579554
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Wei ZL et al. Enhancement of sodium butyrate-induced cell death by hyperthermia in HCT 116 human colorectal cancer cells. Anticancer Res. pmid:18630528
Wang L et al. Sodium butyrate induces human colon carcinoma HT-29 cell apoptosis through a mitochondrial pathway. J. Int. Med. Res. pmid:19589263
Chin HL et al. Fedbatch operation using Clostridium acetobutylicum suspension culture as biocatalyst for enhancing hydrogen production. Biotechnol. Prog. pmid:12675576
Rossi DL et al. A new mammalian host cell with enhanced survival enables completely serum-free development of high-level protein production cell lines. Biotechnol. Prog. pmid:21473000
Han L et al. Sodium butyrate activates erythroid-specific 5-aminolevulinate synthase gene through Sp1 elements at its promoter. Blood Cells Mol. Dis. pmid:18555711
Kim GH et al. Epigenetic mechanisms of pulmonary hypertension. Pulm Circ pmid:22140624
Cai G et al. Metabolic flux network and analysis of fermentative hydrogen production. Biotechnol. Adv. pmid:21362466
Taylor AJ and Beck CW Histone deacetylases are required for amphibian tail and limb regeneration but not development. Mech. Dev. pmid:22947425
Ghosh SK et al. Short, discontinuous exposure to butyrate effectively sensitizes latently EBV-infected lymphoma cells to nucleoside analogue antiviral agents. Blood Cells Mol. Dis. pmid:17161633
Rodriguez J et al. Enhanced production of monomeric interferon-beta by CHO cells through the control of culture conditions. Biotechnol. Prog. pmid:15903237
Lim SJ et al. Effect of butyrate on the heregulin/ErbB-mediated proliferation of human colorectal cancer cells. Mol Med Rep pmid:21475856
Hu YC et al. Enhancement and prolongation of baculovirus-mediated expression in mammalian cells: focuses on strategic infection and feeding. Biotechnol. Prog. pmid:12675574
Bayés M and Rabasseda X Gateways to clinical trials. Methods Find Exp Clin Pharmacol pmid:18389098
Gennari L et al. Total extract of Beta vulgaris var. cicla seeds versus its purified phenolic components: antioxidant activities and antiproliferative effects against colon cancer cells. Phytochem Anal pmid:21337646
Liu L et al. Butyrate interferes with the differentiation and function of human monocyte-derived dendritic cells. Cell. Immunol. pmid:22698927
Joachimiak R et al. Influence of sodium butyrate on hepatocellular carcinoma (hepG2) and glioblastoma (C6) cell lines in vitro. Acta Pol Pharm pmid:18323252
Krokowicz L et al. Sodium butyrate and short chain fatty acids in prevention of travellers' diarrhoea: a randomized prospective study. Travel Med Infect Dis pmid:24063909
pmid:11071567