| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Tumor Virus Infections | D014412 | 8 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zielke HR et al. | Synthesis of glutamate and glutamine in dibutyryl cyclic AMP-treated astrocytes. | 1989 | Neurosci. Lett. | pmid:2563906 |
| Thakur MK and Prasad S | Age-specific methylation of high-mobility-group proteins of the rat liver and its modulation by spermine and sodium butyrate. | 1989 | Mutat. Res. | pmid:2927415 |
| Montiel F et al. | Presence of insulin receptors in cultured glial C6 cells. Regulation by butyrate. | 1989 | Biochem. J. | pmid:2930502 |
| Gonçalves E et al. | Triiodothyronine transport into differentiated and undifferentiated mouse neuroblastoma cells (NB41A3). | 1989 | Endocrinology | pmid:2909368 |
| Denburg JA et al. | Factors influencing basophilic differentiation of HL-60 cells. | 1989 | Int. Arch. Allergy Appl. Immunol. | pmid:2468609 |
| Katoh K and Yajima T | Effects of butyric acid and analogues on amylase release from pancreatic segments of sheep and goats. | 1989 | Pflugers Arch. | pmid:2470024 |
| Schmidt R et al. | Sodium butyrate selectively antagonizes the inhibitory effect of retinoids on cornified envelope formation in cultured human keratinocytes. | 1989 | J. Cell. Physiol. | pmid:2473084 |
| Perrine SP et al. | Sodium butyrate enhances fetal globin gene expression in erythroid progenitors of patients with Hb SS and beta thalassemia. | 1989 | Blood | pmid:2473801 |
| Pramanik SK and Bag J | Expression of muscle-specific proteins is necessary to regulate translation of the mRNA for a 40-kDa housekeeping polypeptide in rat L6 cells. | 1989 | Eur. J. Biochem. | pmid:2473901 |
| Myers DE et al. | The effects of aromatic and aliphatic maleimide crosslinkers on anti-CD5 ricin immunotoxins. | 1989 | J. Immunol. Methods | pmid:2474026 |
| Arock M et al. | Histamine-releasing activity of endogenous peptides on mast cells derived from different sites and species. | 1989 | Int. Arch. Allergy Appl. Immunol. | pmid:2474510 |
| Mossman SP et al. | The effects of 5-azacytidine, 12-O-tetradecanoylphorbol 13-acetate and sodium n-butyrate on reactivation of alphaherpesvirus saimiri from explant cultures of latently infected rabbit dorsal root ganglia. | 1989 | J. Gen. Virol. | pmid:2476529 |
| Foss FM et al. | Alterations in the expression of pp60c-src and p56lck associated with butyrate-induced differentiation of human colon carcinoma cells. | 1989 | Oncogene Res. | pmid:2476706 |
| Brantschen S et al. | Factors influencing proliferation and histamine content of cultured human bone marrow cells. | 1989 | Immunobiology | pmid:2477328 |
| Weaver GA et al. | Constancy of glucose and starch fermentations by two different human faecal microbial communities. | 1989 | Gut | pmid:2920921 |
| Chen HM and Lifschitz CH | Preparation of fecal samples for assay of volatile fatty acids by gas-liquid chromatography and high-performance liquid chromatography. | 1989 | Clin. Chem. | pmid:2910583 |
| Perrine SP et al. | Butyric acid modulates developmental globin gene switching in man and sheep. | 1989 | Adv. Exp. Med. Biol. | pmid:2484761 |
| Crabtree B et al. | Evidence that the production of acetate in rat hepatocytes is a predominantly cytoplasmic process. | 1989 | Biochem. J. | pmid:2564776 |
| Constantoulakis P et al. | On the induction of fetal hemoglobin by butyrates: in vivo and in vitro studies with sodium butyrate and comparison of combination treatments with 5-AzaC and AraC. | 1989 | Blood | pmid:2478217 |
| Ramsdell JS and Tashjian AH | GH4 pituitary cell variants selected as nonresponsive to thyrotropin-releasing hormone-enhanced substratum adhesion are nonresponsive to epidermal growth factor: evidence for a common signaling defect. | 1989 | J. Cell. Physiol. | pmid:2480354 |
| Alberts P | Effects of N6,2'-O-dibutyryladenosine 3',5'-cyclic monophosphate, adenosine, and of oxotremorine and 3-isobutyl-1-methylxanthine on the electrically evoked [3H]acetylcholine secretion in the guinea-pig ileum myenteric plexus. | 1989 | Acta Physiol. Scand. | pmid:2481381 |
| Kubin T et al. | Inhibition of DNA synthesis of adult rat hepatocytes in primary culture by dibutyrylcytidine 3', 5'-cyclic monophosphate. | 1989 | Cell Biol. Int. Rep. | pmid:2481569 |
| Clarke J et al. | A comparison of the effects of various stimulatory agents on t-PA secretion by normal and malignant cell lines. | 1989 | Cell Biochem. Funct. | pmid:2481573 |
| Constantoulakis P et al. | Butyrate stimulates HbF in adult baboons. | 1989 | Prog. Clin. Biol. Res. | pmid:2482502 |
| Schulz M et al. | Regulation by dibutyryl cyclic AMP of carnosine synthesis in astroglia-rich primary cultures kept in serum-free medium. | 1989 | J. Neurochem. | pmid:2462017 |
| Nackerdien Z et al. | Chromatin decondensed by acetylation shows an elevated radiation response. | 1989 | Radiat. Res. | pmid:2922469 |
| Matsui-Yuasa I et al. | Two mechanisms of spermidine/spermine N1-acetyltransferase-induction. | 1989 | Arch. Biochem. Biophys. | pmid:2463788 |
| Casper D and Davies P | Stimulation of choline acetyltransferase activity by retinoic acid and sodium butyrate in a cultured human neuroblastoma. | 1989 | Brain Res. | pmid:2924123 |
| Cox GS and Park KH | Modulation of glycoprotein hormone alpha-subunit levels, alkaline phosphatase activity, and DNA replication by antimetabolites in HeLa cultures. | 1989 | Arch. Biochem. Biophys. | pmid:2463791 |
| Casper D and Davies P | Mechanism of activation of choline acetyltransferase in a human neuroblastoma cell line. | 1989 | Brain Res. | pmid:2924124 |
| Shimamura A and Worcel A | The assembly of regularly spaced nucleosomes in the Xenopus oocyte S-150 extract is accompanied by deacetylation of histone H4. | 1989 | J. Biol. Chem. | pmid:2760072 |
| Chatham JC et al. | The metabolic consequences of hydroperoxide perfusion on the isolated rat heart. | 1989 | Eur. J. Biochem. | pmid:2806248 |
| Jenkins DJ | The link between colon fermentation and systemic disease. | 1989 | Am. J. Gastroenterol. | pmid:2816871 |
| Aizawa K et al. | Placental alkaline phosphatase-like isoenzymes produced by human gastric cancer cells. | 1989 | Acta Pathol. Jpn. | pmid:2686348 |
| Tanaka Y et al. | Enhancement of butyrate-induced differentiation of HT-29 human colon carcinoma cells by 1,25-dihydroxyvitamin D3. | 1989 | Biochem. Pharmacol. | pmid:2688649 |
| Flatow U et al. | Characterization and tumorigenicity of a butyrate-adapted T24 bladder cancer cell line. | 1989 | Cancer Invest. | pmid:2695227 |
| Neogrády Z et al. | Effect of intraruminal butyrate infusion on the plasma insulin level in sheep. | 1989 | Acta Vet. Hung. | pmid:2697146 |
| Gardner SL et al. | Modulation by sodium butyrate of the differentiated status of a clonal pancreatic B-cell line (RIN). | 1989 | Diabetes Res. | pmid:2699445 |
| Binder HJ and Mehta P | Short-chain fatty acids stimulate active sodium and chloride absorption in vitro in the rat distal colon. | 1989 | Gastroenterology | pmid:2925072 |
| Kojima S et al. | Identification of myeloid origin in undifferentiated congenital leukemia by in vitro marrow culture study. | 1989 | Am J Pediatr Hematol Oncol | pmid:2782565 |
| Vijayaraghavan S et al. | Calcium uptake by bovine epididymal spermatozoa is regulated by the redox state of the mitochondrial pyridine nucleotides. | 1989 | Biol. Reprod. | pmid:2752074 |
| Hock RA et al. | Expression of human adenosine deaminase from various strong promoters after gene transfer into human hematopoietic cell lines. | 1989 | Blood | pmid:2752148 |
| Champelovier P et al. | Establishment and characterization of a granulocytic subclone (UM 384) from the monoblastic cell line U 937. | 1989 | Exp. Hematol. | pmid:2753087 |
| Ortiz-Caro J et al. | Organization of the thyroid hormone receptor in the chromatin of C6 glial cells: evidence that changes in receptor levels are not associated with changes in receptor distribution. | 1989 | FEBS Lett. | pmid:2753141 |
| Firmansyah A et al. | Isolated colonocyte metabolism of glucose, glutamine, n-butyrate, and beta-hydroxybutyrate in malnutrition. | 1989 | Gastroenterology | pmid:2753323 |
| Favinger J et al. | Rhodospirillum centenum, sp. nov., a thermotolerant cyst-forming anoxygenic photosynthetic bacterium. | 1989 | Antonie Van Leeuwenhoek | pmid:2757370 |
| Marchant P et al. | A selective inhibitor of N8-acetylspermidine deacetylation in mice and HeLa cells without effects on histone deacetylation. | 1989 | Arch. Biochem. Biophys. | pmid:2757387 |
| Herz F | Effect of human serum on alkaline phosphatase induction in cultured human tumor cells. | 1989 | Experientia | pmid:2759209 |
| Beattie DT et al. | Baclofen antagonism by 4-amino-3-(5-methoxybenzo[b]furan-2-yl) butanoic acid in the cat spinal cord. | 1989 | Neurosci. Lett. | pmid:2761779 |
| Chiao CS and Price JC | Modification of gelatin beadlets for zero-order sustained release. | 1989 | Pharm. Res. | pmid:2762229 |
| Xu K et al. | [Studies on cell surface fibronectin of transformed Syrian hamster lung cells induced by butyric acid]. | 1989 | Shi Yan Sheng Wu Xue Bao | pmid:2763766 |
| Ramanathan B and Smerdon MJ | Enhanced DNA repair synthesis in hyperacetylated nucleosomes. | 1989 | J. Biol. Chem. | pmid:2738057 |
| Ramakrishna BS et al. | Estimation of phenolic conjugation by colonic mucosa. | 1989 | J. Clin. Pathol. | pmid:2738167 |
| Higgins PJ and Ryan MP | Cytoarchitecture of ras oncogene-expressing tumor cells: butyrate modulation of substrate adhesion, cytoskeletal actin content and subcellular microfilament distribution. | 1989 | Int. J. Biochem. | pmid:2684700 |
| Larno S et al. | Sodium butyrate-induced structural and functional modifications in proteins of cultured rabbit articular chondrocytes. | 1989 | Cell. Mol. Biol. | pmid:2731193 |
| Eisner DA et al. | A novel method for absolute calibration of intracellular pH indicators. | 1989 | Pflugers Arch. | pmid:2740208 |
| Tokunaga T et al. | Utilization and excretion of a new sweetener, fructooligosaccharide (Neosugar), in rats. | 1989 | J. Nutr. | pmid:2495342 |
| Perry CA and Annunziato AT | Influence of histone acetylation on the solubility, H1 content and DNase I sensitivity of newly assembled chromatin. | 1989 | Nucleic Acids Res. | pmid:2740216 |
| Cheng KJ et al. | The characterization and ultrastructure of two new strains of Butyrivibrio. | 1989 | Can. J. Microbiol. | pmid:2743214 |
| Toribara NW et al. | Heterogeneity in the induction and expression of carcinoembryonic antigen-related antigens in human colon cancer cell lines. | 1989 | Cancer Res. | pmid:2720685 |
| Hatch M and Geaghan JP | Oxidative metabolism of rabbit and rat intestine with short chain fatty acids and glucose: an evaluation of data analysis. | 1989 | Comp. Biochem. Physiol., B | pmid:2721161 |
| Kemp LM and Latchman DS | Regulated transcription of herpes simplex virus immediate-early genes in neuroblastoma cells. | 1989 | Virology | pmid:2548331 |
| Briers TW et al. | Establishment and characterization of a human ovarian neoplastic cell line, DO-s. | 1989 | Cancer Res. | pmid:2548714 |
| Nakada MT et al. | Genetic regulation of beta 2-adrenergic receptors in 3T3-L1 fibroblasts. | 1989 | Biochem. J. | pmid:2549959 |
| Kurakata S et al. | Lysis of P3HR-1 cells induced to enter the viral cycle by antibody-dependent and independent immunological mechanisms. | 1989 | Cell. Immunol. | pmid:2550147 |
| Sharp NA et al. | Epstein-Barr virus replication in interferon-treated cells. | 1989 | J. Gen. Virol. | pmid:2550580 |
| Lü GZ et al. | [The biological effect of sodium butyrate (NaBT) on SGC-7901 cells]. | 1989 | Shi Yan Sheng Wu Xue Bao | pmid:2552715 |
| Radsak K et al. | Induction by sodium butyrate of cytomegalovirus replication in human endothelial cells. | 1989 | Arch. Virol. | pmid:2552958 |
| James DE et al. | Isoproterenol stimulates phosphorylation of the insulin-regulatable glucose transporter in rat adipocytes. | 1989 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2554313 |
| Lotan R et al. | Modulation of galactoside-binding lectins in tumor cells by differentiation-inducing agents. | 1989 | Cancer Lett. | pmid:2555043 |
| Yamazaki H | [Induction of differentiation in testicular choriocarcinoma cells and its role in cancer therapy]. | 1989 | Nippon Hinyokika Gakkai Zasshi | pmid:2556605 |
| Nakamura CV and Pinto AS | Biological effects of lithium chloride on the insect trypanosomatid Herpetomonas samuelpessoai. | 1989 | Parasitology | pmid:2556681 |
| KraevskiÄ VA et al. | [Oscillatory changes in the transcription and supercoiling of minichromosomal DNA after the withdrawal of butyric acid from a mouse cell culture]. | 1989 | Dokl. Akad. Nauk SSSR | pmid:2635665 |
| Elliott WL et al. | Testing for cell surface forms of class II major histocompatibility complex antigens and Ii by radioiodination, biotinylation, and membrane immunofluorescence. | 1989 | Am. J. Hematol. | pmid:2642651 |
| Neogrády S et al. | Effects of butyrate and insulin and their interaction on the DNA synthesis of rumen epithelial cells in culture. | 1989 | Experientia | pmid:2643531 |
| Herman MM et al. | Neuroblastic differentiation potential of the human retinoblastoma cell lines Y-79 and WERI-Rb1 maintained in an organ culture system. An immunohistochemical, electron microscopic, and biochemical study. | 1989 | Am. J. Pathol. | pmid:2643884 |
| Hoessly MC et al. | Factors responsible for variable reported lineages of HL-60 cells induced to mature with butyric acid. | 1989 | Cancer Res. | pmid:2567205 |
| Poduslo SE | Induction of ketone body enzymes in glial cells. | 1989 | Arch. Biochem. Biophys. | pmid:2568818 |
| Zielke HR et al. | Effect of nerve growth factor on the synthesis of amino acids in PC12 cells. | 1989 | J. Neurosci. Res. | pmid:2569539 |
| Yang ZW et al. | Expression of (+)-3-PPP binding sites in the PC12 pheochromocytoma cell line. | 1989 | Eur. J. Pharmacol. | pmid:2569979 |
| Shirasuna K et al. | Different contents of glycosaminoglycans in a human neoplastic salivary duct cell line and its subclone with a myoepithelial phenotype. | 1989 | Virchows Arch., B, Cell Pathol. | pmid:2570484 |
| Abemayor E and Sidell N | Human neuroblastoma cell lines as models for the in vitro study of neoplastic and neuronal cell differentiation. | 1989 | Environ. Health Perspect. | pmid:2538324 |
| Bartholomeusz RK et al. | Pancreatic islet A2B5- and 3G5-reactive gangliosides are markers of differentiation in rat insulinoma cells. | 1989 | Endocrinology | pmid:2541995 |
| Bertoni G et al. | Intracellular synthesis of Epstein-Barr virus membrane antigen gp350/220. Inhibitory effect of monensin on its expression. | 1989 | Intervirology | pmid:2542183 |
| Bensaadi N et al. | Modulation of enzymatic activities during spontaneous and induced differentiation in a human pancreatic adenocarcinoma cell line CAPAN-1. | 1989 | Int. J. Pancreatol. | pmid:2543714 |
| Daniel P et al. | Pharmacokinetic study of butyric acid administered in vivo as sodium and arginine butyrate salts. | 1989 | Clin. Chim. Acta | pmid:2667816 |
| Düsedau K et al. | [The effect of intravenous administration of butyrate, isobutyrate and isovalerate to lambs aged 8-45 days on the blood plasma content of glucose, insulin, free fatty acids and total alpha-amino-N]. | 1989 | Arch Exp Veterinarmed | pmid:2673127 |
| Stoddart JH et al. | Sodium butyrate suppresses the transforming activity of an activated N-ras oncogene in human colon carcinoma cells. | 1989 | Exp. Cell Res. | pmid:2676572 |
| Walker-Jones D et al. | Stimulation of epithelial membrane antigen expression by transforming growth factor-beta in normal and oncogene-transformed human mammary epithelial cells. | 1989 | Cancer Res. | pmid:2680064 |
| Resnicoff M and Medrano EE | Growth factors and hormones which affect survival, growth, and differentiation of the MCF-7 stem cells and their descendants. | 1989 | Exp. Cell Res. | pmid:2645148 |
| Gladhaug IP and Christoffersen T | n-butyrate and dexamethasone synergistically modulate the surface expression of epidermal growth factor receptors in cultured rat hepatocytes. | 1989 | FEBS Lett. | pmid:2646145 |
| Hargreaves AJ et al. | Sodium butyrate induces major morphological changes in C6 glioma cells that are correlated with increased synthesis of a spectrin-like protein. | 1989 | Brain Res. Dev. Brain Res. | pmid:2653664 |
| Turner BM | Acetylation and deacetylation of histone H4 continue through metaphase with depletion of more-acetylated isoforms and altered site usage. | 1989 | Exp. Cell Res. | pmid:2653852 |
| Szatkowski MS and Thomas RC | The intrinsic intracellular H+ buffering power of snail neurones. | 1989 | J. Physiol. (Lond.) | pmid:2585301 |
| Takahashi Y et al. | [Application of isocyanate separating agent for acrylic resin]. | 1989 | Shika Zairyo Kikai | pmid:2562349 |
| Tocco DJ et al. | Disposition and metabolism of sodium 4-[(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl)sulfonyl]-gamma -oxobenzenebutanoate in rats and dogs. | 1988 Sep-Oct | Drug Metab. Dispos. | pmid:2906591 |
| Tocco DJ et al. | The physiological disposition of aerosolized 4-[(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl)sulfonyl]-gamma -oxobenzenebutanoate (L-648,051) in rats. | 1988 Sep-Oct | Drug Metab. Dispos. | pmid:2906592 |
| Lacroix J et al. | In vitro and in vivo activity of 1-aryl-3-(2-chloroethyl) urea derivatives as new antineoplastic agents. | 1988 Jul-Aug | Anticancer Res. | pmid:3052247 |
| Spotti D et al. | Intermediary metabolism and glycemic control in insulin-dependent diabetic uremic patients treated by continuous peritoneal dialysis. | 1988 | Nephron | pmid:3041295 |
| Chatham J et al. | Inhibition of glucose phosphorylation by fatty acids in the perfused rat heart. | 1988 | FEBS Lett. | pmid:3169268 |