butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Merle-Beral H et al. | A T chronic lymphocytic leukemia with large granular lymphocytes. Phenotype and functions of leukemic cells under in vitro treatment by differentiation inducers. | 1987 | Cancer | pmid:3545432 |
Nakanishi T and Hashimoto K | The differential reactivity of benign and malignant nevomelanocytic lesions with mouse monoclonal antibody TNKH1. | 1987 | Cancer | pmid:3545436 |
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Nelson NF et al. | Modulation of secreted plasminogen activator activity of human renal carcinoma cells by dimethylsulfoxide, butyrate and retinoate. | 1987 | Cancer Lett. | pmid:3548947 |
Milsted A et al. | Phenotypes of HeLa S3 variant cell lines resistant to growth inhibition by sodium butyrate. | 1987 | In Vitro Cell. Dev. Biol. | pmid:2439485 |
Gudas JM and Hankinson O | Regulation of cytochrome P-450c in differentiated and dedifferentiated rat hepatoma cells: role of the Ah receptor. | 1987 | Somat. Cell Mol. Genet. | pmid:2821631 |
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Van Dyck E and Piot P | Enzyme profile of Haemophilus ducreyi strains isolated on different continents. | 1987 | Eur. J. Clin. Microbiol. | pmid:3032608 |
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Kameyama T et al. | [Behavioral pharmacological action of Ca-4-(3,5-dihydroxy-3-methylpenthylamido) butyrate (mevalonic GABA, MV-GABA)]. | 1987 | Nippon Yakurigaku Zasshi | pmid:3034749 |
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Oya Y et al. | The biological activity of hydrogen peroxide. III. Induction of Epstein-Barr virus via indirect action, as compared with TPA and teleocidin. | 1987 | Int. J. Cancer | pmid:3036721 |
Boos H et al. | Enhancement of Epstein-Barr virus membrane protein (LMP) expression by serum, TPA, or n-butyrate in latently infected Raji cells. | 1987 | Virology | pmid:3037776 |
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Menon R et al. | Metabolism of 7,12-dimethylbenz[a]anthracene by mouse mammary cells in serum-free organ culture medium. | 1987 | Eur J Cancer Clin Oncol | pmid:3038562 |
Garr-Peters JM and Ho CS | Oxygen transfer in the corneal-contact lens system. | 1987 | Crit Rev Biomed Eng | pmid:3319414 |
Gum JR et al. | Effects of sodium butyrate on human colonic adenocarcinoma cells. Induction of placental-like alkaline phosphatase. | 1987 | J. Biol. Chem. | pmid:3805014 |
Peleran JC et al. | Identification of the cooked food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and its N-acetylated and 3-N-demethylated metabolites in rat urine. | 1987 | Toxicology | pmid:3810661 |
Byrd JC and Alho H | Differentiation of PC12 pheochromocytoma cells by sodium butyrate. | 1987 | Brain Res. | pmid:3815113 |
Gout PW | Transient requirement for prolactin as a growth initiator following treatment of autonomous Nb2 node rat lymphoma cell cultures with butyrate. | 1987 | Cancer Res. | pmid:3815371 |
Janati-Idrissi R et al. | [Selection of mutants of Clostridium acetobutylicum defective in production of acetone]. | 1987 May-Jun | Ann. Inst. Pasteur Microbiol. | pmid:3620201 |
Edsbäcker S et al. | Metabolic acetal splitting of budesonide. A novel inactivation pathway for topical glucocorticoids. | 1987 May-Jun | Drug Metab. Dispos. | pmid:2886320 |
Galenko-IaroshevckiÄ PA et al. | [Complex formation of lithium hydroxybutyrate with ions of Na+, K+, Ba2+, Mg2+, and Ca2+]. | 1987 Nov-Dec | Farmakol Toksikol | pmid:3436425 |
Bergeret M et al. | Immunomodulatory effects of arginine butyrate. | 1987 Oct-Dec | J. Biol. Regul. Homeost. Agents | pmid:3140599 |
Kan YY et al. | Effects of polar organic compounds on gynecologic cancers. | 1988 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:3224317 |
Clouet PM and Bourre JM | Ketone body utilization for lipid synthesis in the murine sciatic nerve: alterations in the dysmyelinating trembler mutant. | 1988 | J. Neurochem. | pmid:3361304 |
Salam S | Inhibitor(S) of prostaglandin endoperoxide synthase and lipoxygenase activity in extracts of barley. | 1988 | Pak J Pharm Sci | pmid:16414615 |
Staecker JL et al. | Sodium butyrate preserves aspects of the differentiated phenotype of normal adult rat hepatocytes in culture. | 1988 | J. Cell. Physiol. | pmid:2899578 |
Hutt-Taylor SR et al. | Sodium butyrate and a T lymphocyte cell line-derived differentiation factor induce basophilic differentiation of the human promyelocytic leukemia cell line HL-60. | 1988 | Blood | pmid:2446679 |
Rossi JF et al. | Phenotypic and functional analysis of 1,25-dihydroxyvitamin D3 receptor mediated modulation of the human myeloma cell line RPMI 8226. | 1988 | Cancer Res. | pmid:2830017 |
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Takeyasu K et al. | Ouabain-sensitive (Na+ + K+)-ATPase activity expressed in mouse L cells by transfection with DNA encoding the alpha-subunit of an avian sodium pump. | 1988 | J. Biol. Chem. | pmid:2831227 |
Bahn RS et al. | n-Butyrate increases c-erb A oncogene expression in human colon fibroblasts. | 1988 | Biochem. Biophys. Res. Commun. | pmid:2447891 |
Sorimachi K | Induction of alkaline phosphatase activity by synergistic action of dibutyryl cyclic adenosine monophosphate, prednisolone, butyrate and sodium chloride in cultured cells. | 1988 | Cell Biochem. Funct. | pmid:2832093 |
Tamura RN and Cox GS | Effect of pyrimidine deoxynucleosides and sodium butyrate on expression of the glycoprotein hormone alpha-subunit and placental alkaline phosphatase in HeLa cells. | 1988 | Biochim. Biophys. Acta | pmid:2449248 |
Halgunset J et al. | Butyrate effects on growth, morphology, and fibronectin production in PC-3 prostatic carcinoma cells. | 1988 | Prostate | pmid:2450342 |
Sack TL et al. | Cyclic-AMP-stimulated synthesis and release of carcinoembryonic antigen by pancreatic cancer cells. | 1988 | Int. J. Pancreatol. | pmid:2834472 |
Ladoux A et al. | An increase in intracellular pH is a general response of promonocytic cells to differentiating agents. | 1988 | FEBS Lett. | pmid:2455658 |
Pennypacker KR et al. | Calmodulin-binding proteins in human Y-79 retinoblastoma and HTB-14 glioma cell lines. | 1988 | J. Neurochem. | pmid:2834519 |
Kassis S et al. | Modulation of the beta-adrenergic receptor-coupled adenylate cyclase by chemical inducers of differentiation: effects on beta receptors and the inhibitory regulatory protein Gi. | 1988 | J. Recept. Res. | pmid:2455808 |
Murray SA and Taylor F | Dibutyryl cyclic AMP modulation of gap junctions in SW-13 human adrenal cortical tumor cells. | 1988 | Am. J. Anat. | pmid:2835894 |
Spiegel S | Insertion of ganglioside GM1 into rat glioma C6 cells renders them susceptible to growth inhibition by the B subunit of cholera toxin. | 1988 | Biochim. Biophys. Acta | pmid:2835987 |
Sorimachi K et al. | Requirement of serum pretreatment for induction of alkaline phosphatase activity with prednisolone, butyrate, dibutyryl cyclic adenosine monophosphate and NaCl in human liver cells continuously cultured in serum-free medium. | 1988 | Cell Struct. Funct. | pmid:2836073 |
Lee KL et al. | The effects of sodium butyrate on the retinoic acid-induced changes in 1,25-dihydroxyvitamin D3 receptors in tumorigenic and nontumorigenic bone derived cell lines. | 1988 | Endocrinology | pmid:2836162 |
Gross JL et al. | Plasminogen activator and inhibitor activity in human glioma cells and modulation by sodium butyrate. | 1988 | Cancer Res. | pmid:3121170 |
Baskova IP et al. | Thrombolytic agents of the preparation from the medicinal leeches. | 1988 | Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. | pmid:2459014 |
Boerner P and Saier MH | Effects of 5-azacytidine, sodium butyrate, and phorbol esters on amino acid transport system A in a kidney epithelial cell line, MDCK: evidence for multiple mechanisms of regulation. | 1988 | J. Cell. Physiol. | pmid:2459137 |
Burns LJ et al. | Butyrate induces selective transcriptional activation of a hypomethylated embryonic globin gene in adult erythroid cells. | 1988 | Blood | pmid:2460154 |
Perrine SP et al. | Butyrate infusions in the ovine fetus delay the biologic clock for globin gene switching. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2460870 |
Herlyn M et al. | Regulatory factors that determine growth and phenotype of normal human melanocytes. | 1988 | Exp. Cell Res. | pmid:2461309 |
Inhorn L et al. | Restoration of adenylate cyclase responsiveness in murine myeloid leukemia permits inhibition of proliferation by hormone. Butyrate augments catalytic activity of adenylate cyclase. | 1988 | Blood | pmid:3128344 |
Asher C and Garty H | Aldosterone increases the apical Na+ permeability of toad bladder by two different mechanisms. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3140240 |
Brass EP and Beyerinck RA | Effects of propionate and carnitine on the hepatic oxidation of short- and medium-chain-length fatty acids. | 1988 | Biochem. J. | pmid:3134008 |
Toscani A et al. | Molecular analysis of sodium butyrate-induced growth arrest. | 1988 | Oncogene Res. | pmid:3144695 |
Graham KA and Buick RN | Sodium butyrate induces differentiation in breast cancer cell lines expressing the estrogen receptor. | 1988 | J. Cell. Physiol. | pmid:3294239 |
Durix A and Jean-Blain C | [Influence of fasting and the dietary lipid content on ketogenesis in isolated rabbit hepatocytes]. | 1988 | Reprod Nutr Dev | pmid:3254599 |
Nakagawa T et al. | Transcriptional and posttranscriptional modulation of calcitonin gene expression by sodium n-butyrate in cultured human medullary thyroid carcinoma. | 1988 | Cancer Res. | pmid:3258183 |
Filippovich IV et al. | Effect of the inducers of cellular differentiation and of ionizing radiation on thymus lymphocytes: chromatin degradation and programmed cell death. | 1988 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:3258296 |
Gladhaug IP et al. | Effects of butyrate on epidermal growth factor receptor binding, morphology, and DNA synthesis in cultured rat hepatocytes. | 1988 | Cancer Res. | pmid:3263190 |
Yeger H et al. | Phenotypic and molecular characterization of inducible human neuroblastoma cell lines. | 1988 | Differentiation | pmid:3243386 |
Kéri G et al. | Comparison of the tyrosine kinase activity with the proliferation rate in human colon solid tumors and tumor cell lines. | 1988 | Tumour Biol. | pmid:3206110 |
Nishiya I et al. | Relationship between changes of the steroid receptor and synchronization in human endometrial adenocarcinoma cells in vitro. | 1988 | Cytometry | pmid:3208623 |
Yusta B et al. | Mechanism of L-triiodothyronine (T3) uptake by glial C6 cells: regulation by butyrate. | 1988 | Mol. Cell. Endocrinol. | pmid:3208994 |
Ortiz-Caro J et al. | Proliferation and differentiation are not directly related to H1(0) accumulation in cultured glial cells. | 1988 | Brain Res. | pmid:3219583 |
Takenaga K et al. | Differential expression of a tropomyosin isoform in low- and high-metastatic Lewis lung carcinoma cells. | 1988 | Mol. Cell. Biol. | pmid:3221870 |
Maddox AM and Haddox MK | Characteristics of cyclic AMP enhancement of retinoic acid induction of increased transglutaminase activity in HL60 cells. | 1988 | Exp. Cell Biol. | pmid:2903078 |
Hellweg R et al. | Nerve growth factor synthesis in cultured rat iris: modulation by endogenous transmitter substances. | 1988 | Exp. Cell Res. | pmid:2844567 |
Hidal JT and Kaplan MM | Inhibition of thyroxine 5'-deiodination type II in cultured human placental cells by cortisol, insulin, 3', 5'-cyclic adenosine monophosphate, and butyrate. | 1988 | Metab. Clin. Exp. | pmid:2838733 |
Laeng H et al. | Participation of mitochondrial proliferation in morphological differentiation of murine mastocytoma cells. | 1988 | Exp. Cell Res. | pmid:2844569 |
Courtin F et al. | Induction of type II 5'-deiodinase activity by cyclic adenosine 3', 5'-monophosphate in cultured rat astroglial cells. | 1988 | Endocrinology | pmid:2841100 |
Langdon SP et al. | Effect of sodium butyrate and other differentiation inducers on poorly differentiated human ovarian adenocarcinoma cell lines. | 1988 | Cancer Res. | pmid:3167862 |
Rodgers RJ et al. | Secretion of progesterone and prostaglandins by cells of bovine corpora lutea from three stages of the luteal phase. | 1988 | J. Endocrinol. | pmid:2842428 |
Kaneko Y et al. | Fibroblast-like transformation and c-myc gene alteration of human hepatocytes induced by novobiocin and butyrate. | 1988 | Biochem. Biophys. Res. Commun. | pmid:2843181 |
Sutherland GR et al. | A BrdU-enhanceable fragile site or viral modification site at 11q23.1 in lymphoblastoid cultures. | 1988 | Cytogenet. Cell Genet. | pmid:2843323 |
Powers AC et al. | Sodium butyrate increases glucagon and insulin gene expression by recruiting immunocytochemically negative cells to produce hormone. | 1988 | Diabetes | pmid:2843409 |
Kisauzi DN and Leek BF | Liver blood flow and volatile fatty acid utilization in sheep before and after carbon tetrachloride treatment. | 1988 | J. Comp. Pathol. | pmid:3417915 |
Bidet M et al. | Role of monocarboxylic acid transport in intracellular pH regulation of isolated proximal cells. | 1988 | Biochim. Biophys. Acta | pmid:3342236 |
Ortiz-Caro J et al. | Short chain fatty acids modulate nuclear receptor and extranuclear L-triiodothyronine levels in glial C6 cells by different mechanisms. | 1988 | Endocrinology | pmid:2836168 |
Reading CL et al. | Analysis of cell surface glycoprotein changes related to hematopoietic differentiation. | 1988 | J. Cell. Biochem. | pmid:3392108 |
Staecker JL and Pitot HC | The effect of sodium butyrate on tyrosine aminotransferase induction in primary cultures of normal adult rat hepatocytes. | 1988 | Arch. Biochem. Biophys. | pmid:2895606 |
Tatsuka M et al. | An improved method of electroporation for introducing biologically active foreign genes into cultured mammalian cells. | 1988 | Exp. Cell Res. | pmid:3409976 |
Drucker DJ et al. | Proglucagon gene expression and posttranslational processing in a hamster islet cell line. | 1988 | Endocrinology | pmid:3416818 |
Chan WC et al. | Large granular lymphocyte proliferation: an analysis of T-cell receptor gene arrangement and expression and the effect of in vitro culture with inducing agents. | 1988 | Blood | pmid:2961380 |
Szabad J et al. | The effects of two mutations connected with chromatin functions on female germ-line cells of Drosophila. | 1988 | Mol. Gen. Genet. | pmid:3422705 |
Giancotti V et al. | Butyrate effect on nuclear proteins of two Chinese hamster cell lines. | 1988 | Exp. Cell Res. | pmid:3335229 |
Spector R | Fatty acid transport through the blood-brain barrier. | 1988 | J. Neurochem. | pmid:3335863 |
Effects of short-chain fatty acids on a human colon carcinoma cell line. | 1988 | Nutr. Rev. | pmid:3340339 | |
Hallows KR et al. | Effects of the differentiating agents sodium butyrate and N-methylformamide on the oxygen enhancement ratio of human colon tumor cells. | 1988 | Radiat. Res. | pmid:3340722 |
Berry RD and Paraskeva C | Expression of carcinoembryonic antigen by adenoma and carcinoma derived epithelial cell lines: possible marker of tumour progression and modulation of expression by sodium butyrate. | 1988 | Carcinogenesis | pmid:3345582 |
Annunziato AT et al. | Treatment with sodium butyrate inhibits the complete condensation of interphase chromatin. | 1988 | Chromosoma | pmid:3349872 |
Leith JT | Effects of sodium butyrate and 3-aminobenzamide on survival of Chinese hamster HA-1 cells after X irradiation. | 1988 | Radiat. Res. | pmid:3353504 |
Reynier MO et al. | Influence of lipid-rich diets on intestinal cholesterol uptake. | 1988 | Ann. Nutr. Metab. | pmid:3355108 |
Zhang DE and Nelson DA | Histone acetylation in chicken erythrocytes. Rates of deacetylation in immature and mature red blood cells. | 1988 | Biochem. J. | pmid:3355515 |