butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hamasaki Y et al. | Butyric acid enhances cyclooxygenase activity in rat basophilic leukemia 2H3 cells. | 1988 | Nippon Ketsueki Gakkai Zasshi | pmid:3144111 |
Kan YY et al. | Effects of polar organic compounds on gynecologic cancers. | 1988 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:3224317 |
Staecker JL et al. | Sodium butyrate preserves aspects of the differentiated phenotype of normal adult rat hepatocytes in culture. | 1988 | J. Cell. Physiol. | pmid:2899578 |
Zhu XZ and Chuang DM | Differential regulation by butyrate and dibutyryl cyclic AMP of delta-opioid, alpha 2-adrenergic, and muscarinic cholinergic receptors in NCB-20 cells. | 1988 | J. Neurochem. | pmid:2826684 |
Rossi JF et al. | Phenotypic and functional analysis of 1,25-dihydroxyvitamin D3 receptor mediated modulation of the human myeloma cell line RPMI 8226. | 1988 | Cancer Res. | pmid:2830017 |
Takeyasu K et al. | Ouabain-sensitive (Na+ + K+)-ATPase activity expressed in mouse L cells by transfection with DNA encoding the alpha-subunit of an avian sodium pump. | 1988 | J. Biol. Chem. | pmid:2831227 |
Sorimachi K | Induction of alkaline phosphatase activity by synergistic action of dibutyryl cyclic adenosine monophosphate, prednisolone, butyrate and sodium chloride in cultured cells. | 1988 | Cell Biochem. Funct. | pmid:2832093 |
Sack TL et al. | Cyclic-AMP-stimulated synthesis and release of carcinoembryonic antigen by pancreatic cancer cells. | 1988 | Int. J. Pancreatol. | pmid:2834472 |
Pennypacker KR et al. | Calmodulin-binding proteins in human Y-79 retinoblastoma and HTB-14 glioma cell lines. | 1988 | J. Neurochem. | pmid:2834519 |
Nishimura J et al. | Regulation of biosynthesis and phosphorylation of P210bcr/abl protein during differentiation induction of K 562 cells. | 1988 | Leuk. Res. | pmid:2464113 |
Baskova IP et al. | Thrombolytic agents of the preparation from the medicinal leeches. | 1988 | Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. | pmid:2459014 |
Inhorn L et al. | Restoration of adenylate cyclase responsiveness in murine myeloid leukemia permits inhibition of proliferation by hormone. Butyrate augments catalytic activity of adenylate cyclase. | 1988 | Blood | pmid:3128344 |
Asher C and Garty H | Aldosterone increases the apical Na+ permeability of toad bladder by two different mechanisms. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3140240 |
Rhoads DB et al. | Evidence for expression of the facilitated glucose transporter in rat hepatocytes. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3194405 |
Schönfeld P et al. | On the mechanism of the so-called uncoupling effect of medium- and short-chain fatty acids. | 1988 | Biochim. Biophys. Acta | pmid:3196710 |
Graham KA and Buick RN | Sodium butyrate induces differentiation in breast cancer cell lines expressing the estrogen receptor. | 1988 | J. Cell. Physiol. | pmid:3294239 |
Durix A and Jean-Blain C | [Influence of fasting and the dietary lipid content on ketogenesis in isolated rabbit hepatocytes]. | 1988 | Reprod Nutr Dev | pmid:3254599 |
Nakagawa T et al. | Transcriptional and posttranscriptional modulation of calcitonin gene expression by sodium n-butyrate in cultured human medullary thyroid carcinoma. | 1988 | Cancer Res. | pmid:3258183 |
Filippovich IV et al. | Effect of the inducers of cellular differentiation and of ionizing radiation on thymus lymphocytes: chromatin degradation and programmed cell death. | 1988 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:3258296 |
Campbell M and Chader GJ | Retinoblastoma cells in tissue culture. | 1988 | Ophthalmic Paediatr Genet | pmid:3068600 |
Ohwaki K | [High carboxylic acid level in the gingival crevicular fluid (GCF) of the patients with advanced periodontal disease]. | 1988 | Nihon Shishubyo Gakkai Kaishi | pmid:3078007 |
Herold KM and Rothberg PG | Evidence for a labile intermediate in the butyrate induced reduction of the level of c-myc RNA in SW837 rectal carcinoma cells. | 1988 | Oncogene | pmid:3078950 |
Hidal JT and Kaplan MM | Inhibition of thyroxine 5'-deiodination type II in cultured human placental cells by cortisol, insulin, 3', 5'-cyclic adenosine monophosphate, and butyrate. | 1988 | Metab. Clin. Exp. | pmid:2838733 |
Courtin F et al. | Induction of type II 5'-deiodinase activity by cyclic adenosine 3', 5'-monophosphate in cultured rat astroglial cells. | 1988 | Endocrinology | pmid:2841100 |
Langdon SP et al. | Effect of sodium butyrate and other differentiation inducers on poorly differentiated human ovarian adenocarcinoma cell lines. | 1988 | Cancer Res. | pmid:3167862 |
Kisauzi DN and Leek BF | Liver blood flow and volatile fatty acid utilization in sheep before and after carbon tetrachloride treatment. | 1988 | J. Comp. Pathol. | pmid:3417915 |
Ortiz-Caro J et al. | Short chain fatty acids modulate nuclear receptor and extranuclear L-triiodothyronine levels in glial C6 cells by different mechanisms. | 1988 | Endocrinology | pmid:2836168 |
Leith JT et al. | Changes in X-ray sensitivity and glutathione content of human colon tumor cells after exposure to the differentiation-inducing agent sodium butyrate. | 1988 | Radiat. Res. | pmid:3375444 |
Joshi SS et al. | Effects of differentiation inducing chemicals on in vivo malignancy and NK susceptibility of metastatic lymphoma cells. | 1988 | Cancer Detect. Prev. | pmid:3390859 |
Kamech N and Seif R | Evidence for new cellular proteins which may negatively control DNA replication or cell growth in rat 3T3 fibroblasts. | 1988 | Exp. Cell Res. | pmid:3391246 |
Reading CL et al. | Analysis of cell surface glycoprotein changes related to hematopoietic differentiation. | 1988 | J. Cell. Biochem. | pmid:3392108 |
Tatsuka M et al. | An improved method of electroporation for introducing biologically active foreign genes into cultured mammalian cells. | 1988 | Exp. Cell Res. | pmid:3409976 |
Drucker DJ et al. | Proglucagon gene expression and posttranslational processing in a hamster islet cell line. | 1988 | Endocrinology | pmid:3416818 |
Szabad J et al. | The effects of two mutations connected with chromatin functions on female germ-line cells of Drosophila. | 1988 | Mol. Gen. Genet. | pmid:3422705 |
Virtanen I et al. | Expression of intermediate filaments and synaptophysin show neuronal properties and lack of glial characteristics in Y79 retinoblastoma cells. | 1988 | Lab. Invest. | pmid:3141718 |
Lacroix J et al. | In vitro and in vivo activity of 1-aryl-3-(2-chloroethyl) urea derivatives as new antineoplastic agents. | 1988 Jul-Aug | Anticancer Res. | pmid:3052247 |
Tocco DJ et al. | Disposition and metabolism of sodium 4-[(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl)sulfonyl]-gamma -oxobenzenebutanoate in rats and dogs. | 1988 Sep-Oct | Drug Metab. Dispos. | pmid:2906591 |
Tocco DJ et al. | The physiological disposition of aerosolized 4-[(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl)sulfonyl]-gamma -oxobenzenebutanoate (L-648,051) in rats. | 1988 Sep-Oct | Drug Metab. Dispos. | pmid:2906592 |
Gonçalves E et al. | Triiodothyronine transport into differentiated and undifferentiated mouse neuroblastoma cells (NB41A3). | 1989 | Endocrinology | pmid:2909368 |
Bägli DJ et al. | Natural killer sensitivity of colorectal carcinoma targets. Correlation with degree of differentiation. | 1989 | Arch Surg | pmid:2910252 |
Bretton RH and Pennypacker JP | Butyric acid causes morphological changes in cultured chondrocytes through alterations in the extracellular matrix. | 1989 | J. Cell. Physiol. | pmid:2910883 |
Otaka M et al. | Antibody-mediated targeting of differentiation inducers to tumor cells: inhibition of colonic cancer cell growth in vitro and in vivo. A preliminary note. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2912449 |
Perrine SP et al. | Butyric acid modulates developmental globin gene switching in man and sheep. | 1989 | Adv. Exp. Med. Biol. | pmid:2484761 |
Wiese B and Martin K | Basic extraction studies of benzylpenicillin and its determination by liquid chromatography with pre-column derivatisation. | 1989 | J Pharm Biomed Anal | pmid:2488609 |
Matsuhisa T et al. | Induction of blood coagulation factor VIII by sodium butyrate in Balb/c 3T3 cells. | 1989 | Exp. Cell Res. | pmid:2491813 |
Schulz M et al. | Regulation by dibutyryl cyclic AMP of carnosine synthesis in astroglia-rich primary cultures kept in serum-free medium. | 1989 | J. Neurochem. | pmid:2462017 |
Matsui-Yuasa I et al. | Two mechanisms of spermidine/spermine N1-acetyltransferase-induction. | 1989 | Arch. Biochem. Biophys. | pmid:2463788 |
Cox GS and Park KH | Modulation of glycoprotein hormone alpha-subunit levels, alkaline phosphatase activity, and DNA replication by antimetabolites in HeLa cultures. | 1989 | Arch. Biochem. Biophys. | pmid:2463791 |
Chatham JC et al. | The metabolic consequences of hydroperoxide perfusion on the isolated rat heart. | 1989 | Eur. J. Biochem. | pmid:2806248 |
Jenkins DJ | The link between colon fermentation and systemic disease. | 1989 | Am. J. Gastroenterol. | pmid:2816871 |
Aizawa K et al. | Placental alkaline phosphatase-like isoenzymes produced by human gastric cancer cells. | 1989 | Acta Pathol. Jpn. | pmid:2686348 |
Tanaka Y et al. | Enhancement of butyrate-induced differentiation of HT-29 human colon carcinoma cells by 1,25-dihydroxyvitamin D3. | 1989 | Biochem. Pharmacol. | pmid:2688649 |
Flatow U et al. | Characterization and tumorigenicity of a butyrate-adapted T24 bladder cancer cell line. | 1989 | Cancer Invest. | pmid:2695227 |
Neogrády Z et al. | Effect of intraruminal butyrate infusion on the plasma insulin level in sheep. | 1989 | Acta Vet. Hung. | pmid:2697146 |
Gardner SL et al. | Modulation by sodium butyrate of the differentiated status of a clonal pancreatic B-cell line (RIN). | 1989 | Diabetes Res. | pmid:2699445 |
Neogrády S et al. | The effects of butyrate and glucagon on the proliferation of ruminal epithelial cells in culture. | 1989 | Vet. Res. Commun. | pmid:2773302 |
Binder HJ and Mehta P | Short-chain fatty acids stimulate active sodium and chloride absorption in vitro in the rat distal colon. | 1989 | Gastroenterology | pmid:2925072 |
Newman JD et al. | Induction of the insulin receptor and other differentiation markers by sodium butyrate in the Burkitt lymphoma cell, Raji. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2786417 |
Kojima S et al. | Identification of myeloid origin in undifferentiated congenital leukemia by in vitro marrow culture study. | 1989 | Am J Pediatr Hematol Oncol | pmid:2782565 |
Ramanathan B and Smerdon MJ | Enhanced DNA repair synthesis in hyperacetylated nucleosomes. | 1989 | J. Biol. Chem. | pmid:2738057 |
Ramakrishna BS et al. | Estimation of phenolic conjugation by colonic mucosa. | 1989 | J. Clin. Pathol. | pmid:2738167 |
Higgins PJ and Ryan MP | Cytoarchitecture of ras oncogene-expressing tumor cells: butyrate modulation of substrate adhesion, cytoskeletal actin content and subcellular microfilament distribution. | 1989 | Int. J. Biochem. | pmid:2684700 |
Larno S et al. | Sodium butyrate-induced structural and functional modifications in proteins of cultured rabbit articular chondrocytes. | 1989 | Cell. Mol. Biol. | pmid:2731193 |
Eisner DA et al. | A novel method for absolute calibration of intracellular pH indicators. | 1989 | Pflugers Arch. | pmid:2740208 |
Perry CA and Annunziato AT | Influence of histone acetylation on the solubility, H1 content and DNase I sensitivity of newly assembled chromatin. | 1989 | Nucleic Acids Res. | pmid:2740216 |
Cheng KJ et al. | The characterization and ultrastructure of two new strains of Butyrivibrio. | 1989 | Can. J. Microbiol. | pmid:2743214 |
Toribara NW et al. | Heterogeneity in the induction and expression of carcinoembryonic antigen-related antigens in human colon cancer cell lines. | 1989 | Cancer Res. | pmid:2720685 |
Hatch M and Geaghan JP | Oxidative metabolism of rabbit and rat intestine with short chain fatty acids and glucose: an evaluation of data analysis. | 1989 | Comp. Biochem. Physiol., B | pmid:2721161 |
Terada T et al. | Gas chromatographic assay and disposition of 6-chloro-2-pyridylmethyl nitrate, a new antianginal drug, in healthy volunteers. | 1989 | J Pharm Sci | pmid:2724079 |
Bohan CA et al. | Mutational analysis of sodium butyrate inducible elements in the human immunodeficiency virus type I long terminal repeat. | 1989 | Virology | pmid:2800338 |
Furukawa M et al. | [Suppressive effect of CDDP on induction of the Epstein-Barr virus antigen synthesis by n-butyrate]. | 1989 | Nippon Jibiinkoka Gakkai Kaiho | pmid:2545850 |
Iavarone A et al. | 3-D changes in neuroblastoma x glioma hybrid (NG 108-15) cell differentiation as studied by SEM and TEM. | 1989 | Prog. Clin. Biol. Res. | pmid:2546164 |
Sussman NL et al. | Intestinal alkaline phosphatase is secreted bidirectionally from villous enterocytes. | 1989 | Am. J. Physiol. | pmid:2546440 |
Ryan MP and Higgins PJ | Sodium-n-butyrate induces secretion and substrate accumulation of p52 in Kirsten sarcoma virus-transformed rat kidney fibroblasts. | 1989 | Int. J. Biochem. | pmid:2546834 |
Yanase S and Sugawara K | Inhibition of chemical Epstein-Barr virus induction by dimethyl sulfoxide and related polar compounds. | 1989 | Intervirology | pmid:2546900 |
Balzarini J et al. | Synthesis and antiviral activity of the enantiomeric forms of carba-5-iodo-2'-deoxyuridine and carba-(E)-5-(2-bromovinyl)-2'-deoxyuridine. | 1989 | J. Med. Chem. | pmid:2547072 |
Kemp LM and Latchman DS | Regulated transcription of herpes simplex virus immediate-early genes in neuroblastoma cells. | 1989 | Virology | pmid:2548331 |
Briers TW et al. | Establishment and characterization of a human ovarian neoplastic cell line, DO-s. | 1989 | Cancer Res. | pmid:2548714 |
Nakada MT et al. | Genetic regulation of beta 2-adrenergic receptors in 3T3-L1 fibroblasts. | 1989 | Biochem. J. | pmid:2549959 |
Kurakata S et al. | Lysis of P3HR-1 cells induced to enter the viral cycle by antibody-dependent and independent immunological mechanisms. | 1989 | Cell. Immunol. | pmid:2550147 |
Mickley LA et al. | Modulation of the expression of a multidrug resistance gene (mdr-1/P-glycoprotein) by differentiating agents. | 1989 | J. Biol. Chem. | pmid:2572588 |
Bates SE et al. | Expression of a drug resistance gene in human neuroblastoma cell lines: modulation by retinoic acid-induced differentiation. | 1989 | Mol. Cell. Biol. | pmid:2573830 |
Wasserman L et al. | Sodium butyrate enhances the activities of membranal enzymes and increases drug sensitivity in a cell line from ascitic fluid of an ovarian carcinoma patient. | 1989 | Eur J Cancer Clin Oncol | pmid:2576649 |
Sorimachi K et al. | Inhibitory effect of dibutyryl cyclic adenosine monophosphate on the induction of alkaline phosphatase in human fetal liver cell line. | 1989 | Biochim. Biophys. Acta | pmid:2535785 |
Benjamin LA et al. | Alterations in plasminogen activator and inhibitor activity during the differentiation of a human neuroblastoma cell line, SMS-KAN. | 1989 | Cancer Lett. | pmid:2537681 |
Campbell MA et al. | Y-79 retinoblastoma cells: isolation and characterization of clonal lineages. | 1989 | Exp. Eye Res. | pmid:2537744 |
Abemayor E and Sidell N | Human neuroblastoma cell lines as models for the in vitro study of neoplastic and neuronal cell differentiation. | 1989 | Environ. Health Perspect. | pmid:2538324 |
Bartholomeusz RK et al. | Pancreatic islet A2B5- and 3G5-reactive gangliosides are markers of differentiation in rat insulinoma cells. | 1989 | Endocrinology | pmid:2541995 |
Bertoni G et al. | Intracellular synthesis of Epstein-Barr virus membrane antigen gp350/220. Inhibitory effect of monensin on its expression. | 1989 | Intervirology | pmid:2542183 |
Bensaadi N et al. | Modulation of enzymatic activities during spontaneous and induced differentiation in a human pancreatic adenocarcinoma cell line CAPAN-1. | 1989 | Int. J. Pancreatol. | pmid:2543714 |
Daniel P et al. | Pharmacokinetic study of butyric acid administered in vivo as sodium and arginine butyrate salts. | 1989 | Clin. Chim. Acta | pmid:2667816 |
Düsedau K et al. | [The effect of intravenous administration of butyrate, isobutyrate and isovalerate to lambs aged 8-45 days on the blood plasma content of glucose, insulin, free fatty acids and total alpha-amino-N]. | 1989 | Arch Exp Veterinarmed | pmid:2673127 |
Stoddart JH et al. | Sodium butyrate suppresses the transforming activity of an activated N-ras oncogene in human colon carcinoma cells. | 1989 | Exp. Cell Res. | pmid:2676572 |
Walker-Jones D et al. | Stimulation of epithelial membrane antigen expression by transforming growth factor-beta in normal and oncogene-transformed human mammary epithelial cells. | 1989 | Cancer Res. | pmid:2680064 |
Resnicoff M and Medrano EE | Growth factors and hormones which affect survival, growth, and differentiation of the MCF-7 stem cells and their descendants. | 1989 | Exp. Cell Res. | pmid:2645148 |
Gladhaug IP and Christoffersen T | n-butyrate and dexamethasone synergistically modulate the surface expression of epidermal growth factor receptors in cultured rat hepatocytes. | 1989 | FEBS Lett. | pmid:2646145 |
Hargreaves AJ et al. | Sodium butyrate induces major morphological changes in C6 glioma cells that are correlated with increased synthesis of a spectrin-like protein. | 1989 | Brain Res. Dev. Brain Res. | pmid:2653664 |
Turner BM | Acetylation and deacetylation of histone H4 continue through metaphase with depletion of more-acetylated isoforms and altered site usage. | 1989 | Exp. Cell Res. | pmid:2653852 |
Rome L et al. | Proximal tubule volume regulation in hyperosmotic media: intracellular K+, Na+, and Cl-. | 1989 | Am. J. Physiol. | pmid:2610250 |
Staiano-Coico L et al. | Sodium-N-butyrate induces cytoskeletal rearrangements and formation of cornified envelopes in cultured adult human keratinocytes. | 1989 | Cell Tissue Kinet | pmid:2611852 |