butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Rivero JA and Adunyah SE | Sodium butyrate stimulates PKC activation and induces differential expression of certain PKC isoforms during erythroid differentiation. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9703983 |
Kamitani H et al. | Expression of 15-lipoxygenase by human colorectal carcinoma Caco-2 cells during apoptosis and cell differentiation. | 1998 | J. Biol. Chem. | pmid:9705287 |
Takasaka N et al. | Productive infection of Epstein-Barr virus (EBV) in EBV-genome-positive epithelial cell lines (GT38 and GT39) derived from gastric tissues. | 1998 | Virology | pmid:9705908 |
Litvak DA et al. | Butyrate-induced differentiation of Caco-2 cells is associated with apoptosis and early induction of p21Waf1/Cip1 and p27Kip1. | 1998 | Surgery | pmid:9706134 |
Archer S et al. | Butyrate inhibits colon carcinoma cell growth through two distinct pathways. | 1998 | Surgery | pmid:9706145 |
Poumay Y and Leclercq-Smekens M | In Vitro models of epidermal differentiation. | 1998 | Folia Med (Plovdiv) | pmid:9707806 |
Deinhofer M and Weissenböck H | Diagnosis of diabetes mellitus in a bull by means of butyrate infusion. | 1998 | Zentralbl Veterinarmed A | pmid:9719760 |
Deutsch SI et al. | Ultrastructural and enzymic modulation of HeLa cells induced by sodium butyrate and the effects of cytochalasin B and colcemid. | 1976 | J. Cell. Sci. | pmid:972176 |
Lester SC et al. | Derepression of genes on the human inactive X chromosome: evidence for differences in locus-specific rates of derepression and rates of transfer of active and inactive genes after DNA-mediated transformation. | 1982 | Somatic Cell Genet. | pmid:9732753 |
Perez R et al. | Sodium butyrate upregulates Kupffer cell PGE2 production and modulates immune function. | 1998 | J. Surg. Res. | pmid:9733608 |
Hendzel MJ et al. | Chromatin condensation is not associated with apoptosis. | 1998 | J. Biol. Chem. | pmid:9733739 |
Partington GA and Patient RK | Factor binding to the human gamma-globin gene distal CCAAT site: candidates for repression of the normal gene or activation of HPFH mutants. | 1998 | Br. J. Haematol. | pmid:9734644 |
Itoh F et al. | Insulin and glucagon secretion in lactating cows during heat exposure. | 1998 | J. Anim. Sci. | pmid:9734870 |
Alexandrov I et al. | Sodium butyrate suppresses apoptosis in human Burkitt lymphomas and murine plasmacytomas bearing c-myc translocations. | 1998 | FEBS Lett. | pmid:9738480 |
Zvibel I et al. | Phenotypic characterization of rat hepatoma cell lines and lineage-specific regulation of gene expression by differentiation agents. | 1998 | Differentiation | pmid:9745712 |
Moulding DA et al. | Mcl-1 expression in human neutrophils: regulation by cytokines and correlation with cell survival. | 1998 | Blood | pmid:9746790 |
Mandal M et al. | Nuclear targeting of Bax during apoptosis in human colorectal cancer cells. | 1998 | Oncogene | pmid:9747879 |
Tamagawa K et al. | Proanthocyanidins from barley bran potentiate retinoic acid-induced granulocytic and sodium butyrate-induced monocytic differentiation of HL60 cells. | 1998 | Biosci. Biotechnol. Biochem. | pmid:9757552 |
Valle AB et al. | Colorimetric determination of succinic acid using yeast succinate dehydrogenase. | 1978 | Anal. Biochem. | pmid:9762145 |
Carducci MA et al. | Phenylbutyrate induces apoptosis in human prostate cancer and is more potent than phenylacetate. | 1996 | Clin. Cancer Res. | pmid:9816181 |
Pouillart PR | Role of butyric acid and its derivatives in the treatment of colorectal cancer and hemoglobinopathies. | 1998 | Life Sci. | pmid:9820119 |
Grdisa M | Regulation of glyceraldehyde-3-phosphate dehydrogenase in differentiating HD3 cells. | 1998 | Int. J. Biochem. Cell Biol. | pmid:9839449 |
Grdisa M | Alteration of phosphotyrosine-containing proteins during differentiation of chicken erythroleukemia cells (HD3). | 1998 | Cell Biochem. Funct. | pmid:9857490 |
Kurita-Ochiai T et al. | Lipopolysaccharide stimulates butyric acid-induced apoptosis in human peripheral blood mononuclear cells. | 1999 | Infect. Immun. | pmid:9864191 |
Tuleu C and Chaumeil JC | Small-scale characterization of wet powder masses suitable for extrusion-spheronization. | 1998 | Drug Dev Ind Pharm | pmid:9876604 |
Matsuki H et al. | Specific and non-specific binding of long-chain fatty acids to firefly luciferase: cutoff at octanoate. | 1999 | Biochim. Biophys. Acta | pmid:9878713 |
Butel MJ et al. | Clostridial pathogenicity in experimental necrotising enterocolitis in gnotobiotic quails and protective role of bifidobacteria. | 1998 | J. Med. Microbiol. | pmid:9879939 |
Schneider FH | Effects of sodium butyrate on mouse neuroblastoma cells in culture. | 1976 | Biochem. Pharmacol. | pmid:988837 |
Conway RM et al. | Vincristine- and cisplatin-induced apoptosis in human retinoblastoma. Potentiation by sodium butyrate. | 1998 | Eur. J. Cancer | pmid:9893663 |
Chénais B | Requirement of GATA-1 and p45 NF-E2 expression in butyric acid-induced erythroid differentiation. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9918824 |
Omura S et al. | Bioconversion of leucomycins and its regulation by butyrate in a producing strain. | 1976 | J. Antibiot. | pmid:994332 |
Gasmi M et al. | Requirements for efficient production and transduction of human immunodeficiency virus type 1-based vectors. | 1999 | J. Virol. | pmid:9971760 |
Dobson A et al. | Absorption and exchange of water across rumen epithelium. | 1976 | Am. J. Physiol. | pmid:998805 |