butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Pellizzaro C et al. | Modulation of cell cycle-related protein expression by sodium butyrate in human non-small cell lung cancer cell lines. | 2001 | Int. J. Cancer | pmid:11267976 |
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Engelhard HH et al. | Therapeutic effects of sodium butyrate on glioma cells in vitro and in the rat C6 glioma model. | 2001 | Neurosurgery | pmid:11270553 |
Emenaker NJ and Basson MD | Short chain fatty acids differentially modulate cellular phenotype and c-myc protein levels in primary human nonmalignant and malignant colonocytes. | 2001 | Dig. Dis. Sci. | pmid:11270800 |
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Vessey DA | Isolation and preliminary characterization of the medium-chain fatty acid:CoA ligase responsible for activation of short- and medium-chain fatty acids in colonic mucosa from swine. | 2001 | Dig. Dis. Sci. | pmid:11281196 |
Barlow AL et al. | dSIR2 and dHDAC6: two novel, inhibitor-resistant deacetylases in Drosophila melanogaster. | 2001 | Exp. Cell Res. | pmid:11281647 |
Payan C et al. | Inactivation of hepatitis B virus in plasma by hospital in-use chemical disinfectants assessed by a modified HepG2 cell culture. | 2001 | J. Hosp. Infect. | pmid:11289771 |
Kim NS and Lee GM | Overexpression of bcl-2 inhibits sodium butyrate-induced apoptosis in Chinese hamster ovary cells resulting in enhanced humanized antibody production. | 2000-2001 | Biotechnol. Bioeng. | pmid:11291028 |
Jang TH and Sun SH | Alterations in Ca2+ signaling, and c-fos and nur77 expression are associated with sodium butyrate-induced differentiation of C6 glioma cell. | 2000 | Chin J Physiol | pmid:11292179 |
Cuche G et al. | Desensitization of ileal vagal receptors by short-chain fatty acids in pigs. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11292611 |
Lee KY et al. | Thin layer chromatographic determination of organic acids for rapid identification of bifidobacteria at genus level. | 2001 | J. Microbiol. Methods | pmid:11295192 |
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Zhang X et al. | Hydrogen peroxide-induced changes in intracellular pH of guard cells precede stomatal closure. | 2001 | Cell Res. | pmid:11305323 |
Wang Q et al. | Inhibition of the phosphatidylinositol 3-kinase pathway contributes to HT29 and Caco-2 intestinal cell differentiation. | 2001 | Gastroenterology | pmid:11313308 |
Friedrichs D | On the stimulation of gluconeogenesis by L-lysine in isolated rat kidney cortex tubules. | 1975 | Biochim. Biophys. Acta | pmid:1131363 |
Rashid SF et al. | Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A. | 2001 | Oncogene | pmid:11313934 |
Niitsu N et al. | Downregulation of MLL-CBP fusion gene expression is associated with differentiation of SN-1 cells with t(11;16)(q23;p13). | 2001 | Oncogene | pmid:11313967 |
Enwerem NM et al. | Anthelmintic activity of the stem bark extracts of Berlina grandiflora and one of its active principles, Betulinic acid. | 2001 | Phytomedicine | pmid:11315752 |
Nakamura M et al. | Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor. | 2001 | J. Cell. Physiol. | pmid:11319763 |
Chapman MA | The role of the colonic flora in maintaining a healthy large bowel mucosa. | 2001 | Ann R Coll Surg Engl | pmid:11320933 |
Gaschott T et al. | 1,25-Dihydroxycholecalciferol enhances butyrate-induced p21(Waf1/Cip1) expression. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11322770 |
Pullammanappallil PC et al. | Stable performance of anaerobic digestion in the presence of a high concentration of propionic acid. | 2001 | Bioresour. Technol. | pmid:11333036 |
Tanaka K et al. | Enhanced expression of mRNAs of antisecretory factor-1, gp96, DAD1 and CDC34 in human hepatocellular carcinomas. | 2001 | Biochim. Biophys. Acta | pmid:11335099 |
Yang J et al. | Sodium butyrate induces transcription from the G alpha(i2) gene promoter through multiple Sp1 sites in the promoter and by activating the MEK-ERK signal transduction pathway. | 2001 | J. Biol. Chem. | pmid:11337508 |
Hua J et al. | Evaluation of the expression of NADPH oxidase components during maturation of HL-60 clone 15 cells to eosinophilic lineage. | 2001 | Inflamm. Res. | pmid:11339504 |
Vincan E et al. | Sodium butyrate-induced differentiation of human LIM2537 colon cancer cells decreases GSK-3beta activity and increases levels of both membrane-bound and Apc/axin/GSK-3beta complex-associated pools of beta-catenin. | 2000 | Oncol. Res. | pmid:11341469 |
Itoh N et al. | Cloning and biochemical characterization of Co(2+)-activated bromoperoxidase-esterase (perhydrolase) from Pseudomonas putida IF-3 strain. | 2001 | Biochim. Biophys. Acta | pmid:11342031 |
Boosalis MS et al. | Short-chain fatty acid derivatives stimulate cell proliferation and induce STAT-5 activation. | 2001 | Blood | pmid:11342457 |
Gaskin DJ et al. | Alteration of lipase chain length specificity in the hydrolysis of esters by random mutagenesis. | 2001 | Biotechnol. Bioeng. | pmid:11344447 |
Young RC and Zhang P | The mechanism of propagation of intracellular calcium waves in cultured human uterine myocytes. | 2001 | Am. J. Obstet. Gynecol. | pmid:11349193 |
Lens PN et al. | Effect of the liquid upflow velocity on thermophilic sulphate reduction in acidifying granular sludge reactors. | 2001 | Environ Technol | pmid:11349377 |
Greenberg VL et al. | Histone deacetylase inhibitors promote apoptosis and differential cell cycle arrest in anaplastic thyroid cancer cells. | 2001 | Thyroid | pmid:11349829 |
Hung MW et al. | Differential regulation of placental and germ cell alkaline phosphatases by glucocorticoid and sodium butyrate in human gastric carcinoma cell line TMK-1. | 2001 | Arch. Biochem. Biophys. | pmid:11361139 |
Archer SY et al. | p21 gene regulation during enterocyte differentiation. | 2001 | J. Surg. Res. | pmid:11368530 |
Lopez-Avalos MD et al. | Enhanced maturation of porcine neonatal pancreatic cell clusters with growth factors fails to improve transplantation outcome. | 2001 | Transplantation | pmid:11374418 |
Videla S et al. | Dietary inulin improves distal colitis induced by dextran sodium sulfate in the rat. | 2001 | Am. J. Gastroenterol. | pmid:11374687 |
Miyake H et al. | Overexpression of Bcl-2 regulates sodium butyrate- and/or docetaxel-induced apoptosis in human bladder cancer cells both in vitro and in vivo. | 2001 | Int. J. Cancer | pmid:11391617 |
Ahring BK et al. | Effect of temperature increase from 55 to 65 degrees C on performance and microbial population dynamics of an anaerobic reactor treating cattle manure. | 2001 | Water Res. | pmid:11394779 |
Noble R et al. | Olfactory response to mushroom composting emissions as a function of chemical concentration. | J. Environ. Qual. | pmid:11401265 | |
Setlow JK et al. | Evidence for gene silencing in Haemophilus influenzae. | 2001 | Mutat. Res. | pmid:11406170 |
Vanecková I et al. | Intracellular pH regulation in colonocytes of rat proximal colon. | 2001 | Biochim. Biophys. Acta | pmid:11406345 |
Chan LM et al. | A novel human suspension culture packaging cell line for production of high-titre retroviral vectors. | 2001 | Gene Ther. | pmid:11406764 |