butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kim JS et al. | High-level scu-PA production by butyrate-treated serum-free culture of recombinant CHO cell line. | Biotechnol. Prog. | pmid:15575713 | |
Ohata A et al. | Short-chain fatty acids alter tight junction permeability in intestinal monolayer cells via lipoxygenase activation. | Nutrition | pmid:15975492 | |
Roy MJ et al. | In vitro studies on the inhibition of colon cancer by butyrate and carnitine. | Nutrition | pmid:19619983 | |
Nabandith V et al. | Inhibitory effects of crude alpha-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat. | Asian Pac. J. Cancer Prev. | pmid:15546251 | |
Vester BM et al. | Influence of feeding raw or extruded feline diets on nutrient digestibility and nitrogen metabolism of African wildcats (Felis lybica). | Zoo Biol. | pmid:20095004 | |
Jolly RA et al. | Microvesicular steatosis induced by a short chain fatty acid: effects on mitochondrial function and correlation with gene expression. | Toxicol Pathol | pmid:15503661 | |
Wang Y et al. | Sodium butyrate-induced apoptosis and ultrastructural changes in MCF-7 breast cancer cells. | Ultrastruct Pathol | pmid:27158913 | |
Ibrahim MA | Assessment of insulin stability inside diblock copolymer PEG-PLA microspheres. | Sci Pharm | pmid:21179361 | |
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Becker N et al. | Human intestinal microbiota: characterization of a simplified and stable gnotobiotic rat model. | Gut Microbes | pmid:21637015 | |
NofrarÃas M et al. | Long-term intake of resistant starch improves colonic mucosal integrity and reduces gut apoptosis and blood immune cells. | Nutrition | pmid:17936196 | |
Soto-Cruz O et al. | Modeling of growth, lactate consumption, and volatile fatty acid production by Megasphaera elsdenii cultivated in minimal and complex media. | Biotechnol. Prog. | pmid:11934285 | |
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Mangian HF and Tappenden KA | Butyrate increases GLUT2 mRNA abundance by initiating transcription in Caco2-BBe cells. | JPEN J Parenter Enteral Nutr | pmid:19892901 | |
Kodama N et al. | Induction of myeloperoxidase and nitrotyrosine formation in a human eosinophilic leukemia cell line, EoL-1. | Cell Biochem. Funct. | pmid:15027099 | |
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pmid:16166714 | ||||
Vester BM et al. | Evaluation of nutrient digestibility and fecal characteristics of exotic felids fed horse- or beef-based diets: use of the domestic cat as a model for exotic felids. | Zoo Biol. | pmid:19830746 | |
Singh NP and Lai HC | Synergistic cytotoxicity of artemisinin and sodium butyrate on human cancer cells. | Anticancer Res. | pmid:16309236 | |
Jeon JH et al. | Characterization and its potential application of two esterases derived from the arctic sediment metagenome. | Mar. Biotechnol. | pmid:18814017 | |
Lea MA et al. | Induction of differentiation of colon cancer cells by combined inhibition of kinases and histone deacetylase. | Anticancer Res. | pmid:17465197 | |
Kien CL et al. | Lactulose feeding lowers cecal densities of clostridia in piglets. | JPEN J Parenter Enteral Nutr | pmid:17463144 | |
Karna E et al. | The mechanism of butyrate-induced collagen biosynthesis in cultured fibroblasts. | Acta Pol Pharm | pmid:19719045 | |
Sung YH et al. | Influence of down-regulation of caspase-3 by siRNAs on sodium-butyrate-induced apoptotic cell death of Chinese hamster ovary cells producing thrombopoietin. | Metab. Eng. | pmid:16169764 | |
Orchel A et al. | Influence of sodium butyrate on antioxidative enzymes activity in Caco-2 cell lines. | Acta Pol Pharm | pmid:17357609 | |
Noble R et al. | Olfactory response to mushroom composting emissions as a function of chemical concentration. | J. Environ. Qual. | pmid:11401265 | |
Nishinaga M et al. | Establishment of a microplate-formatted cell-based immunoassay for rapid analysis of nucleotide excision repair ability in human primary cells. | Photochem. Photobiol. | pmid:22220555 | |
Hossain Z et al. | Growth inhibition and induction of differentiation and apoptosis mediated by sodium butyrate in Caco-2 cells with algal glycolipids. | In Vitro Cell. Dev. Biol. Anim. | pmid:16153148 | |
Mackie RI et al. | Biochemical and microbiological evidence for fermentative digestion in free-living land iguanas (Conolophus pallidus) and marine iguanas (Amblyrhynchus cristatus) on the Galápagos archipelago. | Physiol. Biochem. Zool. | pmid:15057723 | |
Drozdowski LA et al. | Short-chain fatty acids and total parenteral nutrition affect intestinal gene expression. | JPEN J Parenter Enteral Nutr | pmid:12005453 | |
Lokshina LY et al. | Modeling of anaerobic degradation of solid slaughterhouse waste: inhibition effects of long-chain fatty acids or ammonia. | Appl. Biochem. Biotechnol. | pmid:12794281 | |
Tekucheva DN et al. | Immobilized purple bacteria for light-driven H2 production from starch and potato fermentation effluents. | Biotechnol. Prog. | pmid:21751433 | |
Loughrin JH et al. | Evaluation of second-generation multistage wastewater treatment system for the removal of malodors from liquid swine waste. | J. Environ. Qual. | pmid:19549951 | |
Oh HK et al. | Effect of N-Acetylcystein on butyrate-treated Chinese hamster ovary cells to improve the production of recombinant human interferon-beta-1a. | Biotechnol. Prog. | pmid:16080696 | |
Orchel A et al. | Quantification of p21 gene expression in Caco-2 cells treated with sodium butyrate using real-time reverse transcription-PCR (RT-PCR) assay. | Acta Pol Pharm | pmid:13678314 | |
pmid: | ||||
Gassull MA et al. | Macronutrients and bioactive molecules: is there a specific role in the management of inflammatory bowel disease? | JPEN J Parenter Enteral Nutr | pmid:15980281 | |
Wang B et al. | Butyrate inhibits functional differentiation of human monocyte-derived dendritic cells. | Cell. Immunol. | pmid:18522857 | |
Scharlau D et al. | Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre. | Mutat. Res. | pmid:19383551 | |
Fang HH et al. | Effects of Mo(VI) on phototrophic hydrogen production by Rhodobacter sphaeroides. | Environ Technol | pmid:21970170 | |
Zhang S et al. | Influence of pulsed electric field treatments on the volatile compounds of milk in comparison with pasteurized processing. | J. Food Sci. | pmid:21535640 | |
Wang Q et al. | Characterization of monocarboxylate transport in human kidney HK-2 cells. | Mol. Pharm. | pmid:17140255 | |
Cenkvári E et al. | Investigations on the effects of Ca-soap of linseed oil on rumen fermentation in sheep and on milk composition of goats. | J Anim Physiol Anim Nutr (Berl) | pmid:15787990 | |
Fathallah H et al. | Differences in response to fetal hemoglobin induction therapy in beta-thalassemia and sickle cell disease. | Blood Cells Mol. Dis. | pmid:19346141 | |
Grebenová D et al. | The proteomic study of sodium butyrate antiproliferative/cytodifferentiation effects on K562 cells. | Blood Cells Mol. Dis. | pmid:16978890 | |
Sandmann G | A nitromethane-based HPLC system alternative to acetonitrile for carotenoid analysis of fruit and vegetables. | Phytochem Anal | pmid:20310077 | |
Sanduja S et al. | The roles of TTP and BRF proteins in regulated mRNA decay. | Wiley Interdiscip Rev RNA | pmid:21278925 | |
Munn AJ et al. | Hindgut plasticity in wallabies fed hay either unchopped or ground and pelleted: fiber is not the only factor. | Physiol. Biochem. Zool. | pmid:19331583 | |
Bartholome AL et al. | Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal piglets. | JPEN J Parenter Enteral Nutr | pmid:15291402 | |
Bijaya G et al. | Synthesis and evaluation of esmolol prodrugs for transdermal delivery. | Drug Deliv | pmid:20553111 |