butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lütke-Eversloh T et al. | Biosynthesis of novel thermoplastic polythioesters by engineered Escherichia coli. | 2002 | Nat Mater | pmid:12618785 |
McMillan L et al. | Opposing effects of butyrate and bile acids on apoptosis of human colon adenoma cells: differential activation of PKC and MAP kinases. | 2003 | Br. J. Cancer | pmid:12618885 |
Ozbun LL et al. | Differentially expressed nucleolar TGF-beta1 target (DENTT) in mouse development. | 2003 | Dev. Dyn. | pmid:12619135 |
Gururaj AE et al. | Antiangiogenic effects of butyric acid involve inhibition of VEGF/KDR gene expression and endothelial cell proliferation. | 2003 | Mol. Cell. Biochem. | pmid:12619895 |
Sawa H et al. | Histone deacetylase inhibitors such as sodium butyrate and trichostatin A inhibit vascular endothelial growth factor (VEGF) secretion from human glioblastoma cells. | 2002 | Brain Tumor Pathol | pmid:12622137 |
Bai L et al. | Regulation of epithelial cell growth by ZBP-89: potential relevance in pancreatic cancer. | 2002 | Int J Gastrointest Cancer | pmid:12622418 |
Henningsson AM et al. | Influences of dietary adaptation and source of resistant starch on short-chain fatty acids in the hindgut of rats. | 2003 | Br. J. Nutr. | pmid:12628027 |
Gerhäuser C et al. | Mechanism-based in vitro screening of potential cancer chemopreventive agents. | 2003 Feb-Mar | Mutat. Res. | pmid:12628514 |
Fang HY et al. | Cyclooxygenase-2 in human non-small cell lung cancer. | 2003 | Eur J Surg Oncol | pmid:12633561 |
Ueda M et al. | Up-regulation of the peroxisomal beta-oxidation system occurs in butyrate-grown Candida tropicalis following disruption of the gene encoding peroxisomal 3-ketoacyl-CoA thiolase. | 2003 | Biochim. Biophys. Acta | pmid:12633682 |
Venkatraman A et al. | Amelioration of dextran sulfate colitis by butyrate: role of heat shock protein 70 and NF-kappaB. | 2003 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12637250 |
Cremin JD et al. | Glucose alleviates ammonia-induced inhibition of short-chain fatty acid metabolism in rat colonic epithelial cells. | 2003 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12637251 |
Shao Y and Marriott P | Separation of positional isomers by the use of coupled shape-selective stationary phase columns. | 2003 | Anal Bioanal Chem | pmid:12638047 |
Kanauchi O et al. | Germinated barley foodstuff, a prebiotic product, ameliorates inflammation of colitis through modulation of the enteric environment. | 2003 | J. Gastroenterol. | pmid:12640526 |
Vernia P et al. | Topical butyrate improves efficacy of 5-ASA in refractory distal ulcerative colitis: results of a multicentre trial. | 2003 | Eur. J. Clin. Invest. | pmid:12641543 |
Skarpidi E et al. | Hydroxamide derivatives of short-chain fatty acids are potent inducers of human fetal globin gene expression. | 2003 | Exp. Hematol. | pmid:12644016 |
KovarÃková P et al. | Photochemical stability of nimesulide. | 2003 | J Pharm Biomed Anal | pmid:12644210 |
Shi W et al. | Induction of a senescent-like phenotype does not confer the ability of bovine immortal cells to support the development of nuclear transfer embryos. | 2003 | Biol. Reprod. | pmid:12646489 |
Sutton JD et al. | Effect of method of application of a fibrolytic enzyme product on digestive processes and milk production in Holstein-Friesian cows. | 2003 | J. Dairy Sci. | pmid:12647961 |
Rouf AS et al. | Evaluation of antidiarrhoeal activity Rumex maritimus root. | 2003 | J Ethnopharmacol | pmid:12648830 |
Chernova MN et al. | Acute regulation of the SLC26A3 congenital chloride diarrhoea anion exchanger (DRA) expressed in Xenopus oocytes. | 2003 | J. Physiol. (Lond.) | pmid:12651923 |
Karlsson S et al. | Expression of Clostridium difficile toxins A and B and their sigma factor TcdD is controlled by temperature. | 2003 | Infect. Immun. | pmid:12654792 |
Tabuchi Y et al. | Development of a conditionally immortalized testicular Sertoli cell line RTS3-3 from adult transgenic rats harboring temperature-sensitive simian virus 40 large T-antigen gene. | 2003 | Cell Struct. Funct. | pmid:12655154 |
Kopecný J et al. | Butyrivibrio hungatei sp. nov. and Pseudobutyrivibrio xylanivorans sp. nov., butyrate-producing bacteria from the rumen. | 2003 | Int. J. Syst. Evol. Microbiol. | pmid:12656174 |
Collard TJ et al. | Transcriptional upregulation of the insulin-like growth factor binding protein IGFBP-3 by sodium butyrate increases IGF-independent apoptosis in human colonic adenoma-derived epithelial cells. | 2003 | Carcinogenesis | pmid:12663497 |
Carbone V et al. | Structure-based design of inhibitors of human L-xylulose reductase modelled into the active site of the enzyme. | 2003 | Bioorg. Med. Chem. Lett. | pmid:12668014 |
Finzer P et al. | Phenylbutyrate inhibits growth of cervical carcinoma cells independent of HPV type and copy number. | 2003 | J. Cancer Res. Clin. Oncol. | pmid:12669235 |
Rabelo FL et al. | Inhibition of ERK1/2 and CREB phosphorylation by caspase-dependent mechanism enhances apoptosis in a fibrosarcoma cell line treated with butyrate. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12670506 |
Hangen L and Bennink MR | Consumption of black beans and navy beans (Phaseolus vulgaris) reduced azoxymethane-induced colon cancer in rats. | 2002 | Nutr Cancer | pmid:12672642 |
Yamazaki Y et al. | HIF-1-dependent VEGF reporter gene assay by a stable transformant of CHO cells. | 2003 | Biol. Pharm. Bull. | pmid:12673017 |
Zhu Y and Yang ST | Adaptation of Clostridium tyrobutyricum for enhanced tolerance to butyric acid in a fibrous-bed bioreactor. | 2003 Mar-Apr | Biotechnol. Prog. | pmid:12675573 |
Hu YC et al. | Enhancement and prolongation of baculovirus-mediated expression in mammalian cells: focuses on strategic infection and feeding. | Biotechnol. Prog. | pmid:12675574 | |
Chin HL et al. | Fedbatch operation using Clostridium acetobutylicum suspension culture as biocatalyst for enhancing hydrogen production. | Biotechnol. Prog. | pmid:12675576 | |
Yan J and Xu YH | Tributyrin inhibits human gastric cancer SGC-7901 cell growth by inducing apoptosis and DNA synthesis arrest. | 2003 | World J. Gastroenterol. | pmid:12679905 |
Nilsson NE et al. | Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12684041 |
Buda A et al. | Butyrate downregulates alpha2beta1 integrin: a possible role in the induction of apoptosis in colorectal cancer cell lines. | 2003 | Gut | pmid:12692060 |
Schauber J et al. | Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways. | 2003 | Gut | pmid:12692061 |
Leisy DJ et al. | Transduction of cultured fish cells with recombinant baculoviruses. | 2003 | J. Gen. Virol. | pmid:12692282 |
Rambhatla L et al. | Generation of hepatocyte-like cells from human embryonic stem cells. | 2003 | Cell Transplant | pmid:12693659 |
Lee SC et al. | Activation of terminal B cell differentiation by inhibition of histone deacetylation. | 2003 | Mol. Immunol. | pmid:12695118 |
Walker TS et al. | Metabolic profiling of root exudates of Arabidopsis thaliana. | 2003 | J. Agric. Food Chem. | pmid:12696935 |
Cao X et al. | Aberrant regulation of human intestinal proglucagon gene expression in the NCI-H716 cell line. | 2003 | Endocrinology | pmid:12697711 |
Sheridan BA et al. | Biofiltration of n-butyric acid for the control of odour. | 2003 | Bioresour. Technol. | pmid:12699941 |
Pind PF et al. | Dynamics of the anaerobic process: effects of volatile fatty acids. | 2003 | Biotechnol. Bioeng. | pmid:12701145 |
Tóth M et al. | Identification of pheromones and optimization of bait composition for click beetle pests (Coleoptera: Elateridae) in Central and Western Europe. | 2003 | Pest Manag. Sci. | pmid:12701702 |
McCarter JP et al. | Analysis and functional classification of transcripts from the nematode Meloidogyne incognita. | 2003 | Genome Biol. | pmid:12702207 |
Baloch MI and Akunna JC | Effect of rapid hydraulic shock loads on the performance of granular bed baffled reactor. | 2003 | Environ Technol | pmid:12703861 |
Zhang WF et al. | Effects of isomalto-oligosaccharides on broiler performance and intestinal microflora. | 2003 | Poult. Sci. | pmid:12710488 |
Le Poul E et al. | Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. | 2003 | J. Biol. Chem. | pmid:12711604 |
Nkondjock A et al. | Assessment of risk associated with specific fatty acids and colorectal cancer among French-Canadians in Montreal: a case-control study. | 2003 | Int J Epidemiol | pmid:12714537 |