butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Sarcoma 180 D012510 21 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Corneal Diseases D003316 13 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Osteosarcoma D012516 50 associated lipids
Carcinoma, Small Cell D018288 21 associated lipids
Hypothyroidism D007037 32 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Melanoma D008545 69 associated lipids
Occupational Diseases D009784 42 associated lipids
Weight Gain D015430 101 associated lipids
Brain Diseases D001927 27 associated lipids
Acidosis D000138 13 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Peritonitis D010538 38 associated lipids
Lymphoma D008223 18 associated lipids
Alzheimer Disease D000544 76 associated lipids
Dentin, Secondary D003809 2 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Leukemia D007938 74 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Periodontal Diseases D010510 15 associated lipids
Dental Leakage D003763 5 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Thalassemia D013789 8 associated lipids
Carcinoma, Ductal, Breast D018270 19 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Nervous System Diseases D009422 37 associated lipids
Phenylketonurias D010661 7 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Starvation D013217 47 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Pregnancy in Diabetics D011254 3 associated lipids
Glycogen Storage Disease Type II D006009 2 associated lipids
Seizures D012640 87 associated lipids
Nerve Degeneration D009410 53 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Pituitary Neoplasms D010911 4 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Periodontitis D010518 22 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Mast-Cell Sarcoma D012515 9 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Intestinal Neoplasms D007414 2 associated lipids
Rhabdomyosarcoma D012208 7 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Radiation Injuries D011832 14 associated lipids
Adenoma D000236 40 associated lipids
Angina Pectoris D000787 27 associated lipids
Poultry Diseases D011201 21 associated lipids
Hyperkinesis D006948 11 associated lipids
Disease Models, Animal D004195 4 associated lipids
HIV Infections D015658 20 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Medulloblastoma D008527 22 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Lymphatic Metastasis D008207 10 associated lipids
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Hepatoblastoma D018197 10 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Acute Lung Injury D055371 33 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Retinoblastoma D012175 12 associated lipids
Genomic Instability D042822 7 associated lipids
Constipation D003248 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Lütke-Eversloh T et al. Biosynthesis of novel thermoplastic polythioesters by engineered Escherichia coli. 2002 Nat Mater pmid:12618785
McMillan L et al. Opposing effects of butyrate and bile acids on apoptosis of human colon adenoma cells: differential activation of PKC and MAP kinases. 2003 Br. J. Cancer pmid:12618885
Ozbun LL et al. Differentially expressed nucleolar TGF-beta1 target (DENTT) in mouse development. 2003 Dev. Dyn. pmid:12619135
Gururaj AE et al. Antiangiogenic effects of butyric acid involve inhibition of VEGF/KDR gene expression and endothelial cell proliferation. 2003 Mol. Cell. Biochem. pmid:12619895
Sawa H et al. Histone deacetylase inhibitors such as sodium butyrate and trichostatin A inhibit vascular endothelial growth factor (VEGF) secretion from human glioblastoma cells. 2002 Brain Tumor Pathol pmid:12622137
Bai L et al. Regulation of epithelial cell growth by ZBP-89: potential relevance in pancreatic cancer. 2002 Int J Gastrointest Cancer pmid:12622418
Henningsson AM et al. Influences of dietary adaptation and source of resistant starch on short-chain fatty acids in the hindgut of rats. 2003 Br. J. Nutr. pmid:12628027
Gerhäuser C et al. Mechanism-based in vitro screening of potential cancer chemopreventive agents. 2003 Feb-Mar Mutat. Res. pmid:12628514
Fang HY et al. Cyclooxygenase-2 in human non-small cell lung cancer. 2003 Eur J Surg Oncol pmid:12633561
Ueda M et al. Up-regulation of the peroxisomal beta-oxidation system occurs in butyrate-grown Candida tropicalis following disruption of the gene encoding peroxisomal 3-ketoacyl-CoA thiolase. 2003 Biochim. Biophys. Acta pmid:12633682
Venkatraman A et al. Amelioration of dextran sulfate colitis by butyrate: role of heat shock protein 70 and NF-kappaB. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12637250
Cremin JD et al. Glucose alleviates ammonia-induced inhibition of short-chain fatty acid metabolism in rat colonic epithelial cells. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12637251
Shao Y and Marriott P Separation of positional isomers by the use of coupled shape-selective stationary phase columns. 2003 Anal Bioanal Chem pmid:12638047
Kanauchi O et al. Germinated barley foodstuff, a prebiotic product, ameliorates inflammation of colitis through modulation of the enteric environment. 2003 J. Gastroenterol. pmid:12640526
Vernia P et al. Topical butyrate improves efficacy of 5-ASA in refractory distal ulcerative colitis: results of a multicentre trial. 2003 Eur. J. Clin. Invest. pmid:12641543
Skarpidi E et al. Hydroxamide derivatives of short-chain fatty acids are potent inducers of human fetal globin gene expression. 2003 Exp. Hematol. pmid:12644016
Kovaríková P et al. Photochemical stability of nimesulide. 2003 J Pharm Biomed Anal pmid:12644210
Shi W et al. Induction of a senescent-like phenotype does not confer the ability of bovine immortal cells to support the development of nuclear transfer embryos. 2003 Biol. Reprod. pmid:12646489
Sutton JD et al. Effect of method of application of a fibrolytic enzyme product on digestive processes and milk production in Holstein-Friesian cows. 2003 J. Dairy Sci. pmid:12647961
Rouf AS et al. Evaluation of antidiarrhoeal activity Rumex maritimus root. 2003 J Ethnopharmacol pmid:12648830
Chernova MN et al. Acute regulation of the SLC26A3 congenital chloride diarrhoea anion exchanger (DRA) expressed in Xenopus oocytes. 2003 J. Physiol. (Lond.) pmid:12651923
Karlsson S et al. Expression of Clostridium difficile toxins A and B and their sigma factor TcdD is controlled by temperature. 2003 Infect. Immun. pmid:12654792
Tabuchi Y et al. Development of a conditionally immortalized testicular Sertoli cell line RTS3-3 from adult transgenic rats harboring temperature-sensitive simian virus 40 large T-antigen gene. 2003 Cell Struct. Funct. pmid:12655154
Kopecný J et al. Butyrivibrio hungatei sp. nov. and Pseudobutyrivibrio xylanivorans sp. nov., butyrate-producing bacteria from the rumen. 2003 Int. J. Syst. Evol. Microbiol. pmid:12656174
Collard TJ et al. Transcriptional upregulation of the insulin-like growth factor binding protein IGFBP-3 by sodium butyrate increases IGF-independent apoptosis in human colonic adenoma-derived epithelial cells. 2003 Carcinogenesis pmid:12663497
Carbone V et al. Structure-based design of inhibitors of human L-xylulose reductase modelled into the active site of the enzyme. 2003 Bioorg. Med. Chem. Lett. pmid:12668014
Finzer P et al. Phenylbutyrate inhibits growth of cervical carcinoma cells independent of HPV type and copy number. 2003 J. Cancer Res. Clin. Oncol. pmid:12669235
Rabelo FL et al. Inhibition of ERK1/2 and CREB phosphorylation by caspase-dependent mechanism enhances apoptosis in a fibrosarcoma cell line treated with butyrate. 2003 Biochem. Biophys. Res. Commun. pmid:12670506
Hangen L and Bennink MR Consumption of black beans and navy beans (Phaseolus vulgaris) reduced azoxymethane-induced colon cancer in rats. 2002 Nutr Cancer pmid:12672642
Yamazaki Y et al. HIF-1-dependent VEGF reporter gene assay by a stable transformant of CHO cells. 2003 Biol. Pharm. Bull. pmid:12673017
Zhu Y and Yang ST Adaptation of Clostridium tyrobutyricum for enhanced tolerance to butyric acid in a fibrous-bed bioreactor. 2003 Mar-Apr Biotechnol. Prog. pmid:12675573
Hu YC et al. Enhancement and prolongation of baculovirus-mediated expression in mammalian cells: focuses on strategic infection and feeding. Biotechnol. Prog. pmid:12675574
Chin HL et al. Fedbatch operation using Clostridium acetobutylicum suspension culture as biocatalyst for enhancing hydrogen production. Biotechnol. Prog. pmid:12675576
Yan J and Xu YH Tributyrin inhibits human gastric cancer SGC-7901 cell growth by inducing apoptosis and DNA synthesis arrest. 2003 World J. Gastroenterol. pmid:12679905
Nilsson NE et al. Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids. 2003 Biochem. Biophys. Res. Commun. pmid:12684041
Buda A et al. Butyrate downregulates alpha2beta1 integrin: a possible role in the induction of apoptosis in colorectal cancer cell lines. 2003 Gut pmid:12692060
Schauber J et al. Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways. 2003 Gut pmid:12692061
Leisy DJ et al. Transduction of cultured fish cells with recombinant baculoviruses. 2003 J. Gen. Virol. pmid:12692282
Rambhatla L et al. Generation of hepatocyte-like cells from human embryonic stem cells. 2003 Cell Transplant pmid:12693659
Lee SC et al. Activation of terminal B cell differentiation by inhibition of histone deacetylation. 2003 Mol. Immunol. pmid:12695118
Walker TS et al. Metabolic profiling of root exudates of Arabidopsis thaliana. 2003 J. Agric. Food Chem. pmid:12696935
Cao X et al. Aberrant regulation of human intestinal proglucagon gene expression in the NCI-H716 cell line. 2003 Endocrinology pmid:12697711
Sheridan BA et al. Biofiltration of n-butyric acid for the control of odour. 2003 Bioresour. Technol. pmid:12699941
Pind PF et al. Dynamics of the anaerobic process: effects of volatile fatty acids. 2003 Biotechnol. Bioeng. pmid:12701145
Tóth M et al. Identification of pheromones and optimization of bait composition for click beetle pests (Coleoptera: Elateridae) in Central and Western Europe. 2003 Pest Manag. Sci. pmid:12701702
McCarter JP et al. Analysis and functional classification of transcripts from the nematode Meloidogyne incognita. 2003 Genome Biol. pmid:12702207
Baloch MI and Akunna JC Effect of rapid hydraulic shock loads on the performance of granular bed baffled reactor. 2003 Environ Technol pmid:12703861
Zhang WF et al. Effects of isomalto-oligosaccharides on broiler performance and intestinal microflora. 2003 Poult. Sci. pmid:12710488
Le Poul E et al. Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. 2003 J. Biol. Chem. pmid:12711604
Nkondjock A et al. Assessment of risk associated with specific fatty acids and colorectal cancer among French-Canadians in Montreal: a case-control study. 2003 Int J Epidemiol pmid:12714537