butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Sarcoma 180 D012510 21 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Corneal Diseases D003316 13 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Osteosarcoma D012516 50 associated lipids
Carcinoma, Small Cell D018288 21 associated lipids
Hypothyroidism D007037 32 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Melanoma D008545 69 associated lipids
Occupational Diseases D009784 42 associated lipids
Weight Gain D015430 101 associated lipids
Brain Diseases D001927 27 associated lipids
Acidosis D000138 13 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Peritonitis D010538 38 associated lipids
Lymphoma D008223 18 associated lipids
Alzheimer Disease D000544 76 associated lipids
Dentin, Secondary D003809 2 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Leukemia D007938 74 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Periodontal Diseases D010510 15 associated lipids
Dental Leakage D003763 5 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Thalassemia D013789 8 associated lipids
Carcinoma, Ductal, Breast D018270 19 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Nervous System Diseases D009422 37 associated lipids
Phenylketonurias D010661 7 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Starvation D013217 47 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Pregnancy in Diabetics D011254 3 associated lipids
Glycogen Storage Disease Type II D006009 2 associated lipids
Seizures D012640 87 associated lipids
Nerve Degeneration D009410 53 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Pituitary Neoplasms D010911 4 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Periodontitis D010518 22 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Mast-Cell Sarcoma D012515 9 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Intestinal Neoplasms D007414 2 associated lipids
Rhabdomyosarcoma D012208 7 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Radiation Injuries D011832 14 associated lipids
Adenoma D000236 40 associated lipids
Angina Pectoris D000787 27 associated lipids
Poultry Diseases D011201 21 associated lipids
Hyperkinesis D006948 11 associated lipids
Disease Models, Animal D004195 4 associated lipids
HIV Infections D015658 20 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Medulloblastoma D008527 22 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Lymphatic Metastasis D008207 10 associated lipids
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Hepatoblastoma D018197 10 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Acute Lung Injury D055371 33 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Retinoblastoma D012175 12 associated lipids
Genomic Instability D042822 7 associated lipids
Constipation D003248 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
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Aguilar EC et al. Oral butyrate reduces oxidative stress in atherosclerotic lesion sites by a mechanism involving NADPH oxidase down-regulation in endothelial cells. 2016 J. Nutr. Biochem. pmid:27261536
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Wang A et al. Sodium butyrate mitigates in vitro ammonia generation in cecal content of laying hens. 2016 Environ Sci Pollut Res Int pmid:27154844
Kapuvári B et al. Improved in vivo antitumor effect of a daunorubicin - GnRH-III bioconjugate modified by apoptosis inducing agent butyric acid on colorectal carcinoma bearing mice. 2016 Invest New Drugs pmid:27146514
Wu Y et al. Influence of Butyrate Loaded Clinoptilolite Dietary Supplementation on Growth Performance, Development of Intestine and Antioxidant Capacity in Broiler Chickens. 2016 PLoS ONE pmid:27104860
Rivera-Chávez F et al. Depletion of Butyrate-Producing Clostridia from the Gut Microbiota Drives an Aerobic Luminal Expansion of Salmonella. 2016 Cell Host Microbe pmid:27078066
Lazarova DL and Bordonaro M Vimentin, colon cancer progression and resistance to butyrate and other HDACis. 2016 J. Cell. Mol. Med. pmid:27072512
Early JV et al. Oxadiazoles Have Butyrate-Specific Conditional Activity against Mycobacterium tuberculosis. 2016 Antimicrob. Agents Chemother. pmid:27044545
He B et al. Effects of sodium butyrate supplementation on reproductive performance and colostrum composition in gilts. 2016 Animal pmid:27040131
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Su CL et al. Epigenetic regulation of BDNF in the learned helplessness-induced animal model of depression. 2016 J Psychiatr Res pmid:26921875
Tanaka S et al. Relationship of Enhanced Butyrate Production by Colonic Butyrate-Producing Bacteria to Immunomodulatory Effects in Normal Mice Fed an Insoluble Fraction of Brassica rapa L. 2016 Appl. Environ. Microbiol. pmid:26921420
Donovan JD et al. Volatile Retention and Morphological Properties of Microencapsulated Tributyrin Varied by Wall Material and Drying Method. 2016 J. Food Sci. pmid:26878682
Wang ZT et al. Histone deacetylase inhibitors suppress mutant p53 transcription via HDAC8/YY1 signals in triple negative breast cancer cells. 2016 Cell. Signal. pmid:26876786
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Ziegler K et al. Butyric acid increases transepithelial transport of ferulic acid through upregulation of the monocarboxylate transporters SLC16A1 (MCT1) and SLC16A3 (MCT4). 2016 Arch. Biochem. Biophys. pmid:26854723
Tao Y et al. Production of Butyrate from Lactate by a Newly Isolated Clostridium sp. BPY5. 2016 Appl. Biochem. Biotechnol. pmid:26842597
Zhu P et al. [Effect and mechanism of inhibition of lipopolysaccharide-induced pulmonary fibrosis by butyric acid]. 2016 Zhonghua Wei Zhong Bing Ji Jiu Yi Xue pmid:26805528
Sayed M et al. Selective oxidation of trimethylolpropane to 2,2-bis(hydroxymethyl)butyric acid using growing cells of Corynebacterium sp. ATCC 21245. 2016 J. Biotechnol. pmid:26804932
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Cang S et al. Hypoacetylation, hypomethylation, and dephosphorylation of H2B histones and excessive histone deacetylase activity in DU-145 prostate cancer cells. 2016 J Hematol Oncol pmid:26759222
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Ng CH and Yang KL Lipase in biphasic alginate beads as a biocatalyst for esterification of butyric acid and butanol in aqueous media. 2016 Enzyme Microb. Technol. pmid:26672465
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Liu Y et al. Dietary resistant starch type 4-derived butyrate attenuates nuclear factor-kappa-B1 through modulation of histone H3 trimethylation at lysine 27. 2016 Food Funct pmid:27713965
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Martín Juárez J et al. Saccharification of microalgae biomass obtained from wastewater treatment by enzymatic hydrolysis. Effect of alkaline-peroxide pretreatment. 2016 Bioresour. Technol. pmid:27372005
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Seki K et al. Varying butyric acid amounts induce different stress- and cell death-related signals in nerve growth factor-treated PC12 cells: implications in neuropathic pain absence during periodontal disease progression. 2016 Apoptosis pmid:26994613
Khan S and Jena G Sodium butyrate reduces insulin-resistance, fat accumulation and dyslipidemia in type-2 diabetic rat: A comparative study with metformin. 2016 Chem. Biol. Interact. pmid:27270450
Zhang Z et al. O-Linked N-Acetylglucosamine (O-GlcNAc) Transferase and O-GlcNAcase Interact with Mi2β Protein at the Aγ-Globin Promoter. 2016 J. Biol. Chem. pmid:27231347
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Popp D et al. The alkaloid gramine in the anaerobic digestion process-inhibition and adaptation of the methanogenic community. 2016 Appl. Microbiol. Biotechnol. pmid:27138201
Endesfelder D et al. Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production. 2016 Microbiome pmid:27114075
Kulcsár A et al. Effects of butyrate on the insulin homeostasis of chickens kept on maize- or wheat-based diets. 2016 Acta Vet. Hung. pmid:27993103
Park MJ and Sohrabji F The histone deacetylase inhibitor, sodium butyrate, exhibits neuroprotective effects for ischemic stroke in middle-aged female rats. 2016 J Neuroinflammation pmid:27905989
Gallo A et al. Relationships among ensiling, nutritional, fermentative, microbiological traits and contamination in corn silages addressed with partial least squares regression. 2016 J. Anim. Sci. pmid:27898868
Estensoro I et al. Dietary Butyrate Helps to Restore the Intestinal Status of a Marine Teleost (Sparus aurata) Fed Extreme Diets Low in Fish Meal and Fish Oil. 2016 PLoS ONE pmid:27898676
Chang MC et al. Effect of Butyrate on Collagen Expression, Cell Viability, Cell Cycle Progression and Related Proteins Expression of MG-63 Osteoblastic Cells. 2016 PLoS ONE pmid:27893752
Zhang T et al. Sodium Butyrate Reduces Colitogenic Immunoglobulin A-Coated Bacteria and Modifies the Composition of Microbiota in IL-10 Deficient Mice. 2016 Nutrients pmid:27886121
Tochio T et al. An Alteration in the Cecal Microbiota Composition by Feeding of 1-Kestose Results in a Marked Increase in the Cecal Butyrate Content in Rats. 2016 PLoS ONE pmid:27861621
Khairy H et al. The NADH:flavin oxidoreductase Nox from Rhodococcus erythropolis MI2 is the key enzyme of 4,4'-dithiodibutyric acid degradation. 2016 Lett. Appl. Microbiol. pmid:27564089
Bencsik R et al. Improved transgene expression in doxycycline-inducible embryonic stem cells by repeated chemical selection or cell sorting. 2016 Stem Cell Res pmid:27591479
Han R et al. Sodium Butyrate Upregulates miR-203 Expression to Exert Anti-Proliferation Effect on Colorectal Cancer Cells. 2016 Cell. Physiol. Biochem. pmid:27771718
Polak U et al. Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming. 2016 Stem Cells Dev. pmid:27615158
Chen WS et al. Effects of histone deacetylase inhibitor sodium butyrate on heroin seeking behavior in the nucleus accumbens in rats. 2016 Brain Res. pmid:27742468
Miao W et al. Sodium Butyrate Promotes Reassembly of Tight Junctions in Caco-2 Monolayers Involving Inhibition of MLCK/MLC2 Pathway and Phosphorylation of PKCβ2. 2016 Int J Mol Sci pmid:27735862
Ain QU et al. Analysis of Differential Efficacy and Affinity of GABA (α1/α2) Selective Modulators. 2016 Mol. Pharm. pmid:27704838