butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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NASU H and SAKAMOTO Y | Studies on the hydroxylation of the benzene moiety of the indole nucleus of indole compounds. III. On the enzymatic formatin of 6-hydroxyindole-3-butyric acid. | 1962 | J. Biochem. | pmid:13937651 |
Gordon MJ and Crabtree B | The effects of propionate and butyrate on acetate metabolism in rat hepatocytes. | 1992 | Int. J. Biochem. | pmid:1397495 |
Chow JC and Jesse BW | Interactions between gluconeogenesis and fatty acid oxidation in isolated sheep hepatocytes. | 1992 | J. Dairy Sci. | pmid:1401366 |
Quigley JD et al. | Effects of lasalocid on selected ruminal and blood metabolites in young calves. | 1992 | J. Dairy Sci. | pmid:1401374 |
Tse CS and Williams DM | Inhibition of human endothelial cell proliferation in vitro in response to n-butyrate and propionate. | 1992 | J. Periodont. Res. | pmid:1403579 |
MACRAE IC et al. | THE DECOMPOSITION OF 4-(2,4-DICHLOROPHENOXY) BUTYRIC ACID BY FLAVOBACTERIUM SP. | 1963 | J. Gen. Microbiol. | pmid:14045525 |
ANNISON EF et al. | THE METABOLISM OF ACETIC ACID, PROPIONIC ACID AND BUTYRIC ACID IN SHEEP. | 1963 | Biochem. J. | pmid:14063864 |
Lutter LC et al. | Effects of histone acetylation on chromatin topology in vivo. | 1992 | Mol. Cell. Biol. | pmid:1406675 |
Chiofalo V et al. | Influence of the method of forage conservation on feeding behaviour, intake and characteristics of reticulo-rumen content, in sheep fed ad libitum. | 1992 | Reprod. Nutr. Dev. | pmid:1418399 |
MATSUZAKI M et al. | PARADOXICAL PHASE OF SLEEP: ITS ARTIFICIAL INDUCTION IN THE CAT BY SODIUM BUTYRATE. | 1964 | Science | pmid:14207466 |
Johnson JA | L-carnitine for treatment of distal ulcerative colitis. | 1992 | Gastroenterology | pmid:1426898 |
Ogawa K et al. | Volatile fatty acids, lactic acid, and pH in the stools of breast-fed and bottle-fed infants. | 1992 | J. Pediatr. Gastroenterol. Nutr. | pmid:1432461 |
Nachtigal MW et al. | Chorionic gonadotrophin and c-myc expression in growing and growth-inhibited (intermediate) trophoblasts. | 1992 Jul-Aug | Placenta | pmid:1438085 |
Roettger V et al. | Multiple acyl-coenzyme A dehydrogenation disorders (MAD) responsive to riboflavin: biochemical studies in fibroblasts. | 1992 | Prog. Clin. Biol. Res. | pmid:1438377 |
JOHNSON RB | The effect of the administration of acetic, propionic, and n-butyric acids upon the blood glucose and ketone body levels of goats. | 1955 | Cornell Vet | pmid:14390951 |
IWAMA K and YAMAMOTO C | Locus of the action of gamma amino butyric acid in the suppression of muscular movements in cats. | 1959 | Tohoku J. Exp. Med. | pmid:14406170 |
KITA T et al. | A possible metabolic pathway of gamma-guanido- and gamma-guanido-beta-oxy-butyric acid by heteroarginase. | 1961 | Jpn. J. Pharmacol. | pmid:14456496 |
Tang DC and Taylor MW | Memory of butyrate induction by the Moloney murine sarcoma virus enhancer-promoter element. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1449468 |
Wilson AJ et al. | TR3/Nur77 in colon cancer cell apoptosis. | 2003 | Cancer Res. | pmid:14500374 |
Kurita-Ochiai T et al. | Cellular events involved in butyric acid-induced T cell apoptosis. | 2003 | J. Immunol. | pmid:14500654 |
Karolewski BA et al. | Comparison of transfection conditions for a lentivirus vector produced in large volumes. | 2003 | Hum. Gene Ther. | pmid:14503964 |
Li B et al. | Expression of butyrate response factor 1 in HTLV-1-transformed cells and its transactivation by tax protein. | 2003 | Arch. Virol. | pmid:14505090 |
RodrÃguez-Cabezas ME et al. | Intestinal anti-inflammatory activity of dietary fiber (Plantago ovata seeds) in HLA-B27 transgenic rats. | 2003 | Clin Nutr | pmid:14512034 |
Klampfer L et al. | Inhibition of interferon gamma signaling by the short chain fatty acid butyrate. | 2003 | Mol. Cancer Res. | pmid:14517348 |
Estival A et al. | Decreased expression of transforming growth factor alpha during differentiation of human pancreatic cancer cells. | 1992 | Gastroenterology | pmid:1451978 |
Vogt JA and Wolever TM | Fecal acetate is inversely related to acetate absorption from the human rectum and distal colon. | 2003 | J. Nutr. | pmid:14519799 |
Um SJ et al. | Potent cytotoxic effects of novel retinamide derivatives in ovarian cancer cells. | 2003 | Biol. Pharm. Bull. | pmid:14519946 |
Smartt HJ et al. | Increased NF-kappaB DNA binding but not transcriptional activity during apoptosis induced by the COX-2-selective inhibitor NS-398 in colorectal carcinoma cells. | 2003 | Br. J. Cancer | pmid:14520472 |
Akah PA et al. | Evaluation of the anti-asthmatic property of Asystasia gangetica leaf extracts. | 2003 | J Ethnopharmacol | pmid:14522429 |
Kyrylenko S et al. | Differential regulation of the Sir2 histone deacetylase gene family by inhibitors of class I and II histone deacetylases. | 2003 | Cell. Mol. Life Sci. | pmid:14523559 |
Alrefai WA et al. | Regulation of butyrate uptake in Caco-2 cells by phorbol 12-myristate 13-acetate. | 2004 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:14525727 |
Lingaas F and Tveit B | Etiology of acetonemia in Norwegian cattle. 2. Effect of butyric acid, valeric acid, and putrescine. | 1992 | J. Dairy Sci. | pmid:1452847 |
Sklan D et al. | Fatty acids, calcium soaps of fatty acids, and cottonseeds fed to high yielding cows. | 1992 | J. Dairy Sci. | pmid:1452851 |
Tung RS et al. | In vitro effects of the thiopeptide A10255 on ruminal fermentation and microbial populations. | 1992 | J. Dairy Sci. | pmid:1452854 |
Zhang T et al. | Biohydrogen production from starch in wastewater under thermophilic condition. | 2003 | J. Environ. Manage. | pmid:14550657 |
Smiricky-Tjardes MR et al. | Dietary galactooligosaccharides affect ileal and total-tract nutrient digestibility, ileal and fecal bacterial concentrations, and ileal fermentative characteristics of growing pigs. | 2003 | J. Anim. Sci. | pmid:14552381 |
López S et al. | Effects of volatile fatty acid supply on their absorption and on water kinetics in the rumen of sheep sustained by intragastric infusions. | 2003 | J. Anim. Sci. | pmid:14552390 |
Lu F et al. | Chromatin remodeling of the Kaposi's sarcoma-associated herpesvirus ORF50 promoter correlates with reactivation from latency. | 2003 | J. Virol. | pmid:14557628 |
Pott I et al. | Detection of unusual carotenoid esters in fresh mango (Mangifera indica L. cv. 'Kent'). | 2003 | Phytochemistry | pmid:14559275 |
Heerdt BG et al. | The intrinsic mitochondrial membrane potential (Deltapsim) is associated with steady-state mitochondrial activity and the extent to which colonic epithelial cells undergo butyrate-mediated growth arrest and apoptosis. | 2003 | Cancer Res. | pmid:14559818 |
Lee IS and Nishikawa A | Polyozellus multiplex, a Korean wild mushroom, as a potent chemopreventive agent against stomach cancer. | 2003 | Life Sci. | pmid:14561527 |
Ferrante RJ et al. | Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice. | 2003 | J. Neurosci. | pmid:14561870 |
Liu XM et al. | Unique induction of p21(WAF1/CIP1)expression by vinorelbine in androgen-independent prostate cancer cells. | 2003 | Br. J. Cancer | pmid:14562033 |
Jenkinson S et al. | Development of a novel high-throughput surrogate assay to measure HIV envelope/CCR5/CD4-mediated viral/cell fusion using BacMam baculovirus technology. | 2003 | J Biomol Screen | pmid:14567799 |
Young SP et al. | A comparison of in vitro acylcarnitine profiling methods for the diagnosis of classical and variant short chain acyl-CoA dehydrogenase deficiency. | 2003 | Clin. Chim. Acta | pmid:14568186 |
Mariani MR et al. | Correlation between butyrate-induced histone hyperacetylation turn-over and c-myc expression. | 2003 | J. Steroid Biochem. Mol. Biol. | pmid:14568568 |
Ji XJ et al. | Effect of fetal hemoglobin-stimulating medicines on the interaction of DNA and protein of important erythroid regulatory elements. | 2003 | Biochem. Cell Biol. | pmid:14569302 |
VanGulck JF et al. | Predicting biogeochemical calcium precipitation in landfill leachate collection systems. | 2003 | Biodegradation | pmid:14571950 |
Mann KK et al. | A retinoid/butyric acid prodrug overcomes retinoic acid resistance in leukemias by induction of apoptosis. | 2003 | Mol. Cancer Res. | pmid:14573791 |
Hrynevych IuP et al. | [Antioxidant properties of rhenium cluster complexes with butyric acid derivatives in blood plasma and erythrocytes]. | 2003 Jan-Feb | Ukr Biokhim Zh (1999) | pmid:14574740 |