butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Sarcoma 180 D012510 21 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Corneal Diseases D003316 13 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Osteosarcoma D012516 50 associated lipids
Carcinoma, Small Cell D018288 21 associated lipids
Hypothyroidism D007037 32 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Melanoma D008545 69 associated lipids
Occupational Diseases D009784 42 associated lipids
Weight Gain D015430 101 associated lipids
Brain Diseases D001927 27 associated lipids
Acidosis D000138 13 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Peritonitis D010538 38 associated lipids
Lymphoma D008223 18 associated lipids
Alzheimer Disease D000544 76 associated lipids
Dentin, Secondary D003809 2 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Leukemia D007938 74 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Periodontal Diseases D010510 15 associated lipids
Dental Leakage D003763 5 associated lipids
Lymphoproliferative Disorders D008232 7 associated lipids
Thalassemia D013789 8 associated lipids
Carcinoma, Ductal, Breast D018270 19 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Nervous System Diseases D009422 37 associated lipids
Phenylketonurias D010661 7 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Starvation D013217 47 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Pregnancy in Diabetics D011254 3 associated lipids
Glycogen Storage Disease Type II D006009 2 associated lipids
Seizures D012640 87 associated lipids
Nerve Degeneration D009410 53 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Pituitary Neoplasms D010911 4 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Periodontitis D010518 22 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Mast-Cell Sarcoma D012515 9 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Intestinal Neoplasms D007414 2 associated lipids
Rhabdomyosarcoma D012208 7 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Radiation Injuries D011832 14 associated lipids
Adenoma D000236 40 associated lipids
Angina Pectoris D000787 27 associated lipids
Poultry Diseases D011201 21 associated lipids
Hyperkinesis D006948 11 associated lipids
Disease Models, Animal D004195 4 associated lipids
HIV Infections D015658 20 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Medulloblastoma D008527 22 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Lymphatic Metastasis D008207 10 associated lipids
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Hepatoblastoma D018197 10 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Acute Lung Injury D055371 33 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Retinoblastoma D012175 12 associated lipids
Genomic Instability D042822 7 associated lipids
Constipation D003248 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Gulfam A et al. Characteristics of lactic acid bacteria isolates and their effect on the fermentation quality of Napier grass silage at three high temperatures. 2017 J. Sci. Food Agric. pmid:27539868
Meenongyai W et al. Effects of forage ensiling and ration fermentation on total mixed ration pH, ruminal fermentation and performance of growing Holstein-Zebu cross steers. 2017 Anim. Sci. J. pmid:28370998
Otto A et al. The protein inventory of Clostridium difficile grown in complex and minimal medium. 2016 Proteomics Clin Appl pmid:27511832
Yin F et al. Transcriptome Analysis Reveals Regulation of Gene Expression for Lipid Catabolism in Young Broilers by Butyrate Glycerides. 2016 PLoS ONE pmid:27508934
Moore JB et al. The Epigenetic Regulator HDAC1 Modulates Transcription of a Core Cardiogenic Program in Human Cardiac Mesenchymal Stromal Cells Through a p53-Dependent Mechanism. 2016 Stem Cells pmid:27501845
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Jawed K et al. Engineered Production of Short Chain Fatty Acid in Escherichia coli Using Fatty Acid Synthesis Pathway. 2016 PLoS ONE pmid:27466817
Hou G et al. Tetracycline removal and effect on the formation and degradation of extracellular polymeric substances and volatile fatty acids in the process of hydrogen fermentation. 2016 Bioresour. Technol. pmid:27070285
Longpré J et al. Impact of mash feeding versus pellets on propionic/butyric acid levels and on total load in the gastrointestinal tract of growing pigs. 2016 J. Anim. Sci. pmid:27065267
Wu Y et al. Influence of Butyrate Loaded Clinoptilolite Dietary Supplementation on Growth Performance, Development of Intestine and Antioxidant Capacity in Broiler Chickens. 2016 PLoS ONE pmid:27104860
Rivera-Chávez F et al. Depletion of Butyrate-Producing Clostridia from the Gut Microbiota Drives an Aerobic Luminal Expansion of Salmonella. 2016 Cell Host Microbe pmid:27078066
Lazarova DL and Bordonaro M Vimentin, colon cancer progression and resistance to butyrate and other HDACis. 2016 J. Cell. Mol. Med. pmid:27072512
Early JV et al. Oxadiazoles Have Butyrate-Specific Conditional Activity against Mycobacterium tuberculosis. 2016 Antimicrob. Agents Chemother. pmid:27044545
He B et al. Effects of sodium butyrate supplementation on reproductive performance and colostrum composition in gilts. 2016 Animal pmid:27040131
Petry FS et al. Histone deacetylase inhibition prevents the impairing effects of hippocampal gastrin-releasing peptide receptor antagonism on memory consolidation and extinction. 2016 Behav. Brain Res. pmid:27025446
Frycz BA et al. Transcript level of AKR1C3 is down-regulated in gastric cancer. 2016 Biochem. Cell Biol. pmid:27019068
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Ortega JF et al. Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein. 2016 Oncotarget pmid:27013579
Kaczmarek SA et al. Effect of different doses of coated butyric acid on growth performance and energy utilization in broilers. 2016 Poult. Sci. pmid:26740137
Jung JM et al. Pseudo catalytic transformation of volatile fatty acids into fatty acid methyl esters. 2016 Bioresour. Technol. pmid:26720136
Xin F et al. Strategies for production of butanol and butyl-butyrate through lipase-catalyzed esterification. 2016 Bioresour. Technol. pmid:26710347
Ng CH and Yang KL Lipase in biphasic alginate beads as a biocatalyst for esterification of butyric acid and butanol in aqueous media. 2016 Enzyme Microb. Technol. pmid:26672465
Han A et al. Cellular Metabolism and Dose Reveal Carnitine-Dependent and -Independent Mechanisms of Butyrate Oxidation in Colorectal Cancer Cells. 2016 J. Cell. Physiol. pmid:26661480
Tiwari P et al. Preventive effects of butyric acid, nicotinamide, calcium glucarate alone or in combination during the 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis via modulation of K-Ras-PI3K-AKTpathway and associated micro RNAs. 2016 Biochimie pmid:26655363
Junicke H et al. Kinetic and thermodynamic control of butyrate conversion in non-defined methanogenic communities. 2016 Appl. Microbiol. Biotechnol. pmid:26403924
Ayers LW et al. Changes in dam and pup behavior following repeated postnatal exposure to a predator odor (TMT): A preliminary investigation in Long-Evans rats. 2016 Dev Psychobiol pmid:26394891
Russo R et al. Sodium butyrate and its synthetic amide derivative modulate nociceptive behaviors in mice. 2016 Pharmacol. Res. pmid:26675718
Reddy YS et al. Study on Synthesis, Characterization and Antiproliferative Activity of Novel Diisopropylphenyl Esters of Selected Fatty Acids. 2016 J Oleo Sci pmid:26666272
Polycarpo GV et al. Effects of lipid sources, lysophospholipids and organic acids in maize-based broiler diets on nutrient balance, liver concentration of fat-soluble vitamins, jejunal microbiota and performance. 2016 Br. Poult. Sci. pmid:27494540
Kim M et al. Butyric acid production from softwood hydrolysate by acetate-consuming Clostridium sp. S1 with high butyric acid yield and selectivity. 2016 Bioresour. Technol. pmid:27474955
Villain H et al. HDAC inhibition promotes both initial consolidation and reconsolidation of spatial memory in mice. 2016 Sci Rep pmid:27270584
Zhang Q et al. Accelerated dysbiosis of gut microbiota during aggravation of DSS-induced colitis by a butyrate-producing bacterium. 2016 Sci Rep pmid:27264309
Xiong H et al. Butyrate upregulates endogenous host defense peptides to enhance disease resistance in piglets via histone deacetylase inhibition. 2016 Sci Rep pmid:27230284
Anderson NA et al. Synthesis and determination of absolute configuration of a non-peptidic αvβ6 integrin antagonist for the treatment of idiopathic pulmonary fibrosis. 2016 Org. Biomol. Chem. pmid:27226381
Subramanian U et al. Retinoic acid and sodium butyrate suppress the cardiac expression of hypertrophic markers and proinflammatory mediators in Npr1 gene-disrupted haplotype mice. 2016 Physiol. Genomics pmid:27199456
Bastiaansen JA et al. Measuring changes in substrate utilization in the myocardium in response to fasting using hyperpolarized [1-(13)C]butyrate and [1-(13)C]pyruvate. 2016 Sci Rep pmid:27150735
Seki K et al. Varying butyric acid amounts induce different stress- and cell death-related signals in nerve growth factor-treated PC12 cells: implications in neuropathic pain absence during periodontal disease progression. 2016 Apoptosis pmid:26994613
Vazquez-DeRose J et al. Hypocretin/orexin antagonism enhances sleep-related adenosine and GABA neurotransmission in rat basal forebrain. 2016 Brain Struct Funct pmid:25431268
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Endesfelder D et al. Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production. 2016 Microbiome pmid:27114075
Gallo A et al. Relationships among ensiling, nutritional, fermentative, microbiological traits and contamination in corn silages addressed with partial least squares regression. 2016 J. Anim. Sci. pmid:27898868
Estensoro I et al. Dietary Butyrate Helps to Restore the Intestinal Status of a Marine Teleost (Sparus aurata) Fed Extreme Diets Low in Fish Meal and Fish Oil. 2016 PLoS ONE pmid:27898676
Chang MC et al. Effect of Butyrate on Collagen Expression, Cell Viability, Cell Cycle Progression and Related Proteins Expression of MG-63 Osteoblastic Cells. 2016 PLoS ONE pmid:27893752
Zhang T et al. Sodium Butyrate Reduces Colitogenic Immunoglobulin A-Coated Bacteria and Modifies the Composition of Microbiota in IL-10 Deficient Mice. 2016 Nutrients pmid:27886121
Tochio T et al. An Alteration in the Cecal Microbiota Composition by Feeding of 1-Kestose Results in a Marked Increase in the Cecal Butyrate Content in Rats. 2016 PLoS ONE pmid:27861621
Tian H et al. Discovery of a Flexible Triazolylbutanoic Acid as a Highly Potent Uric Acid Transporter 1 (URAT1) Inhibitor. 2016 Molecules pmid:27854343
Neis EP et al. Effects of Liver Resection on Hepatic Short-Chain Fatty Acid Metabolism in Humans. 2016 PLoS ONE pmid:27835668