butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Kowalski ZM et al. | Effect of microencapsulated sodium butyrate in the close-up diet on performance of dairy cows in the early lactation period. | 2015 | J. Dairy Sci. | pmid:25726104 |
Pierra M et al. | Specific and efficient electrochemical selection of Geoalkalibacter subterraneus and Desulfuromonas acetoxidans in high current-producing biofilms. | 2015 | Bioelectrochemistry | pmid:25717030 |
Caminero A et al. | Differences in gluten metabolism among healthy volunteers, coeliac disease patients and first-degree relatives. | 2015 | Br. J. Nutr. | pmid:26428276 |
Turon V et al. | Use of fermentative metabolites for heterotrophic microalgae growth: Yields and kinetics. | 2015 | Bioresour. Technol. | pmid:25459841 |
Zgorzynska E et al. | Docosahexaenoic acid attenuates oxidative stress and protects human gingival fibroblasts against cytotoxicity induced by hydrogen peroxide and butyric acid. | 2015 | Arch. Oral Biol. | pmid:25455128 |
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Agostini S et al. | Barley beta-glucan promotes MnSOD expression and enhances angiogenesis under oxidative microenvironment. | 2015 | J. Cell. Mol. Med. | pmid:25388628 |
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Isom CE et al. | Improved conversion efficiencies for n-fatty acid reduction to primary alcohols by the solventogenic acetogen "Clostridium ragsdalei". | 2015 | J. Ind. Microbiol. Biotechnol. | pmid:25410829 |
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Machiels K et al. | A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis. | 2014 | Gut | pmid:24021287 |
Grousseau E et al. | Phosphorus limitation strategy to increase propionic acid flux towards 3-hydroxyvaleric acid monomers in Cupriavidus necator. | 2014 | Bioresour. Technol. | pmid:24365742 |
Yu M et al. | Enhancement of adriamycin cytotoxicity by sodium butyrate involves hTERT downmodulation-mediated apoptosis in human uterine cancer cells. | 2014 | Mol. Carcinog. | pmid:23359532 |
Wei Y et al. | Antidepressant-like effect of sodium butyrate is associated with an increase in TET1 and in 5-hydroxymethylation levels in the Bdnf gene. | 2014 | Int. J. Neuropsychopharmacol. | pmid:25618518 |
Liu J et al. | Sodium butyrate promotes the differentiation of rat bone marrow mesenchymal stem cells to smooth muscle cells through histone acetylation. | 2014 | PLoS ONE | pmid:25548915 |
Procentese A et al. | Continuous xylose fermentation by Clostridium acetobutylicum--kinetics and energetics issues under acidogenesis conditions. | 2014 | Bioresour. Technol. | pmid:24852648 |
Ferrario C et al. | Modulation of fecal Clostridiales bacteria and butyrate by probiotic intervention with Lactobacillus paracasei DG varies among healthy adults. | 2014 | J. Nutr. | pmid:25332478 |
Gong Q et al. | [Sodium butyrate inhibits HMGB1 expression and release and attenuates concanavalin A-induced acute liver injury in mice]. | 2014 | Sheng Li Xue Bao | pmid:25332009 |
Pal A and Dey J | Organogelation by 4-(N-tetradecanoyl)aminohydroxybutyric acids: effect of hydrogen-bonding group in the amphiphile head. | 2014 | J Phys Chem B | pmid:25310731 |
Miletta MC et al. | Butyrate increases intracellular calcium levels and enhances growth hormone release from rat anterior pituitary cells via the G-protein-coupled receptors GPR41 and 43. | 2014 | PLoS ONE | pmid:25310566 |
White MK et al. | Rad51 activates polyomavirus JC early transcription. | 2014 | PLoS ONE | pmid:25310191 |
Miltko R et al. | Can fungal zoospores be the source of energy for the rumen protozoa Eudiplodinium maggii? | 2014 | Anaerobe | pmid:24012688 |
Katzenmaier EM et al. | Impact of sodium butyrate on the network of adhesion/growth-regulatory galectins in human colon cancer in vitro. | 2014 | Anticancer Res. | pmid:25275038 |
Takuma K et al. | Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism. | 2014 | Pharmacol. Biochem. Behav. | pmid:25240644 |
Valvassori SS et al. | Sodium butyrate functions as an antidepressant and improves cognition with enhanced neurotrophic expression in models of maternal deprivation and chronic mild stress. | 2014 | Curr Neurovasc Res | pmid:25233278 |
Nankova BB et al. | Enteric bacterial metabolites propionic and butyric acid modulate gene expression, including CREB-dependent catecholaminergic neurotransmission, in PC12 cells--possible relevance to autism spectrum disorders. | 2014 | PLoS ONE | pmid:25170769 |
Bilgraer R et al. | A new approach combining LC-MS and multivariate statistical analysis for revealing changes in histone modification levels. | 2014 | Mol Biosyst | pmid:25167371 |
Lorenzo JM | Influence of the type of fiber coating and extraction time on foal dry-cured loin volatile compounds extracted by solid-phase microextraction (SPME). | 2014 | Meat Sci. | pmid:23896153 |
Xu G et al. | SAHA regulates histone acetylation, Butyrylation, and protein expression in neuroblastoma. | 2014 | J. Proteome Res. | pmid:25160476 |
Khan S and Jena G | Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-β1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats. | 2014 | Food Chem. Toxicol. | pmid:25158305 |
Khalil NA et al. | In vitro batch cultures of gut microbiota from healthy and ulcerative colitis (UC) subjects suggest that sulphate-reducing bacteria levels are raised in UC and by a protein-rich diet. | 2014 | Int J Food Sci Nutr | pmid:23941288 |
Moeinian M et al. | Beneficial effect of butyrate, Lactobacillus casei and L-carnitine combination in preference to each in experimental colitis. | 2014 | World J. Gastroenterol. | pmid:25152589 |
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Peterson EC and Daugulis AJ | The use of high pressure CO2 -facilitated pH swings to enhance in situ product recovery of butyric acid in a two-phase partitioning bioreactor. | 2014 | Biotechnol. Bioeng. | pmid:24888558 |
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Wang J et al. | Comparative effects of sodium butyrate and flavors on feed intake of lactating sows and growth performance of piglets. | 2014 | Anim. Sci. J. | pmid:24773759 |
Saini M et al. | Metabolic engineering of Escherichia coli for production of butyric acid. | 2014 | J. Agric. Food Chem. | pmid:24773075 |
Dareioti MA et al. | Effect of pH on the anaerobic acidogenesis of agroindustrial wastewaters for maximization of bio-hydrogen production: a lab-scale evaluation using batch tests. | 2014 | Bioresour. Technol. | pmid:24759638 |
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Zhou X et al. | Comparison of the effects of high energy carbon heavy ion irradiation and Eucommia ulmoides Oliv. on biosynthesis butyric acid efficiency in Clostridium tyrobutyricum. | 2014 | Bioresour. Technol. | pmid:24704888 |
Jang YS et al. | Metabolic engineering of Clostridium acetobutylicum for butyric acid production with high butyric acid selectivity. | 2014 | Metab. Eng. | pmid:24704310 |
Syngiridis K et al. | Favouring butyrate production for a new generation biofuel by acidogenic glucose fermentation using cells immobilised on γ-alumina. | 2014 | Bioresour. Technol. | pmid:24690582 |
Leon Carrion S et al. | Combined treatment with sodium butyrate and PD153035 enhances keratinocyte differentiation. | 2014 | Exp. Dermatol. | pmid:24451036 |
Sarkar A et al. | Hippocampal HDAC4 contributes to postnatal fluoxetine-evoked depression-like behavior. | 2014 | Neuropsychopharmacology | pmid:24663010 |
Cueno ME et al. | Butyric acid-induced rat jugular blood cytosolic oxidative stress is associated with SIRT1 decrease. | 2014 | Cell Stress Chaperones | pmid:24052229 |
Lee KH et al. | Hizikia fusiformis fractions successfully improve atopic dermatitis indices in anti-CD3-stimulated splenocytes and 2,4-dinitrochlorobenzene-treated BALB/c mice. | 2014 | J. Pharm. Pharmacol. | pmid:24354475 |
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Kato R et al. | The synergistic effect of 1'-acetoxychavicol acetate and sodium butyrate on the death of human hepatocellular carcinoma cells. | 2014 | Chem. Biol. Interact. | pmid:24480522 |
Saldanha SN et al. | Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate. | 2014 | Exp. Cell Res. | pmid:24518414 |
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Xiao M et al. | Sodium butyrate induces apoptosis of human colon cancer cells by modulating ERK and sphingosine kinase 2. | 2014 | Biomed. Environ. Sci. | pmid:24709100 |
Singh V et al. | Histone deacetylase inhibitors valproic acid and sodium butyrate enhance prostaglandins release in lipopolysaccharide-activated primary microglia. | 2014 | Neuroscience | pmid:24480366 |
Hu WT et al. | Transient folate deprivation in combination with small-molecule compounds facilitates the generation of somatic cell-derived pluripotent stem cells in mice. | 2014 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:24710923 |
Rivkin I et al. | Cancer cell sensitization and improved treatment efficacy by combined sodium butyrate and paclitaxel formulations is cancer-type specific. | 2014 | Int J Pharm | pmid:24370842 |
Yamamura T et al. | Sodium butyrate, a histone deacetylase inhibitor, regulates Lymphangiogenic factors in oral cancer cell line HSC-3. | 2014 | Anticancer Res. | pmid:24692699 |
Aoyama Y et al. | Clozapine ameliorates epigenetic and behavioral abnormalities induced by phencyclidine through activation of dopamine D1 receptor. | 2014 | Int. J. Neuropsychopharmacol. | pmid:24345457 |
Kumar P et al. | All-trans retinoic acid and sodium butyrate enhance natriuretic peptide receptor a gene transcription: role of histone modification. | 2014 | Mol. Pharmacol. | pmid:24714214 |
Górka P et al. | Effect of method of delivery of sodium butyrate on maturation of the small intestine in newborn calves. | 2014 | J. Dairy Sci. | pmid:24342681 |
Dos Santos MP et al. | In vitro antitumor effect of sodium butyrate and zoledronic acid combined with traditional chemotherapeutic drugs: a paradigm of synergistic molecular targeting in the treatment of Ewing sarcoma. | 2014 | Oncol. Rep. | pmid:24316794 |
Núñez-Jaramillo L et al. | Sodium butyrate into the insular cortex during conditioned taste-aversion acquisition delays aversive taste memory extinction. | 2014 | Neuroreport | pmid:24323127 |
Tariq M et al. | Synthesis, spectroscopic, X-ray crystal structure, biological and DNA interaction studies of organotin(IV) complexes of 2-(4-ethoxybenzylidene) butanoic acid. | 2014 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:24322756 |
Gagliano H et al. | High doses of the histone deacetylase inhibitor sodium butyrate trigger a stress-like response. | 2014 | Neuropharmacology | pmid:24212060 |
Tailor D et al. | Sodium butyrate induces DRP1-mediated mitochondrial fusion and apoptosis in human colorectal cancer cells. | 2014 | Mitochondrion | pmid:24177748 |
Peterson AB et al. | Dose-dependent effects of wheel running on cocaine-seeking and prefrontal cortex Bdnf exon IV expression in rats. | 2014 | Psychopharmacology (Berl.) | pmid:24173624 |
Fang CL et al. | Effects of sodium butyrate on growth performance, haematological and immunological characteristics of weanling piglets. | 2014 | J Anim Physiol Anim Nutr (Berl) | pmid:24024579 |
Dengler F et al. | Bicarbonate-dependent transport of acetate and butyrate across the basolateral membrane of sheep rumen epithelium. | 2014 | Acta Physiol (Oxf) | pmid:23927569 |