butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Zimmerman MA et al. | Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells. | 2012 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:22517765 |
Schweigel M et al. | Mechanisms of Mg(2+) transport in cultured ruminal epithelial cells. | 2000 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:10712259 |
Archer SY et al. | The histone deacetylase inhibitor butyrate downregulates cyclin B1 gene expression via a p21/WAF-1-dependent mechanism in human colon cancer cells. | 2005 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16160080 |
Borthakur A et al. | Enteropathogenic Escherichia coli inhibits butyrate uptake in Caco-2 cells by altering the apical membrane MCT1 level. | 2006 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16150873 |
Cuche G et al. | Desensitization of ileal vagal receptors by short-chain fatty acids in pigs. | 2001 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11292611 |
Grider JR and Piland BE | The peristaltic reflex induced by short-chain fatty acids is mediated by sequential release of 5-HT and neuronal CGRP but not BDNF. | 2007 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16973914 |
Bao JX et al. | Triggering role of acid sphingomyelinase in endothelial lysosome-membrane fusion and dysfunction in coronary arteries. | 2010 | Am. J. Physiol. Heart Circ. Physiol. | pmid:20061541 |
Ochiai K et al. | Effects of augmented delivery of pyruvate on myocardial high-energy phosphate metabolism at high workstate. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11557577 |
Rexhaj E et al. | Fetal programming of pulmonary vascular dysfunction in mice: role of epigenetic mechanisms. | 2011 | Am. J. Physiol. Heart Circ. Physiol. | pmid:21536851 |
Park GY et al. | Regulation of macrophage cyclooxygenase-2 gene expression by modifications of histone H3. | 2004 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:14672923 |
Zhao L et al. | ¹H-NMR-based metabonomic analysis of metabolic profiling in diabetic nephropathy rats induced by streptozotocin. | 2011 | Am. J. Physiol. Renal Physiol. | pmid:21228107 |
Nakhoul NL et al. | Ammonium interaction with the epithelial sodium channel. | 2001 | Am. J. Physiol. Renal Physiol. | pmid:11502598 |
Laughery MD et al. | Selective basolateral localization of overexpressed Na-K-ATPase beta1- and beta2- subunits is disrupted by butryate treatment of MDCK cells. | 2007 | Am. J. Physiol. Renal Physiol. | pmid:17344187 |
Kumar P et al. | Inhibition of HDAC enhances STAT acetylation, blocks NF-κB, and suppresses the renal inflammation and fibrosis in haplotype male mice. | 2017 | Am. J. Physiol. Renal Physiol. | pmid:28566502 |
Brown AC et al. | RhCG is the major putative ammonia transporter expressed in the human kidney, and RhBG is not expressed at detectable levels. | 2009 | Am. J. Physiol. Renal Physiol. | pmid:19357182 |
Leipziger J et al. | PKA site mutations of ROMK2 channels shift the pH dependence to more alkaline values. | 2000 | Am. J. Physiol. Renal Physiol. | pmid:11053053 |
Gill RK and Dudeja PK | A novel facet to consider for the effects of butyrate on its target cells. Focus on "The short-chain fatty acid butyrate is a substrate of breast cancer resistance protein". | 2011 | Am. J. Physiol., Cell Physiol. | pmid:21832244 |
Gonçalves P et al. | The short-chain fatty acid butyrate is a substrate of breast cancer resistance protein. | 2011 | Am. J. Physiol., Cell Physiol. | pmid:21775706 |
Lam P et al. | Levels of plasma membrane expression in progressive and benign mutations of the bile salt export pump (Bsep/Abcb11) correlate with severity of cholestatic diseases. | 2007 | Am. J. Physiol., Cell Physiol. | pmid:17855769 |
Loffing-Cueni D et al. | Trafficking of GFP-tagged DeltaF508-CFTR to the plasma membrane in a polarized epithelial cell line. | 2001 | Am. J. Physiol., Cell Physiol. | pmid:11698247 |
Nakhoul NL et al. | pH sensitivity of ammonium transport by Rhbg. | 2010 | Am. J. Physiol., Cell Physiol. | pmid:20810915 |
Cooper GJ and Fong P | Relationship between intracellular pH and chloride in Xenopus oocytes expressing the chloride channel ClC-0. | 2003 | Am. J. Physiol., Cell Physiol. | pmid:12388074 |
Said HM et al. | Mechanism of nicotinic acid transport in human liver cells: experiments with HepG2 cells and primary hepatocytes. | 2007 | Am. J. Physiol., Cell Physiol. | pmid:17928533 |
Kiela PR et al. | Molecular mechanism of rat NHE3 gene promoter regulation by sodium butyrate. | 2007 | Am. J. Physiol., Cell Physiol. | pmid:17344314 |
Krishnan S et al. | Apical NHE isoforms differentially regulate butyrate-stimulated Na absorption in rat distal colon. | 2003 | Am. J. Physiol., Cell Physiol. | pmid:12878493 |
Resta-Lenert S et al. | Inhibition of epithelial chloride secretion by butyrate: role of reduced adenylyl cyclase expression and activity. | 2001 | Am. J. Physiol., Cell Physiol. | pmid:11698242 |
Cao XX et al. | Histone deacetylase inhibitor downregulation of bcl-xl gene expression leads to apoptotic cell death in mesothelioma. | 2001 | Am. J. Respir. Cell Mol. Biol. | pmid:11713097 |
Andrews FM et al. | In vitro effects of hydrochloric acid and various concentrations of acetic, propionic, butyric, or valeric acids on bioelectric properties of equine gastric squamous mucosa. | 2006 | Am. J. Vet. Res. | pmid:17078749 |
Minder HP et al. | In vitro fermentation of feces from normal and chronically diarrheal horses. | 1980 | Am. J. Vet. Res. | pmid:6447466 |
Allemann M et al. | Effect of sodium butyric acid, sodium valerianic acid, and osmolarity on contractility of specimens of intestinal wall obtained from the cecum and spiral colon of healthy cows. | 2000 | Am. J. Vet. Res. | pmid:10850845 |
Targowski SP and Klucinski W | Reduction in mitogenic response of bovine lymphocytes by ketone bodies. | 1983 | Am. J. Vet. Res. | pmid:6603180 |
Mills SW et al. | Evaluation of the effects of short-chain fatty acids and extracellular pH on bovine neutrophil function in vitro. | 2006 | Am. J. Vet. Res. | pmid:17078753 |
Theodorou EC et al. | Activation of the AtoSC two-component system in the absence of the AtoC N-terminal receiver domain in E. coli. | 2011 | Amino Acids | pmid:20563612 |
Pinto JT et al. | Chemopreventive mechanisms of α-keto acid metabolites of naturally occurring organoselenium compounds. | 2011 | Amino Acids | pmid:20383543 |
Abecia L et al. | Biodiversity and fermentative activity of caecal microbial communities in wild and farm rabbits from Spain. | 2012 | Anaerobe | pmid:22561060 |
Dunkley KD et al. | Growth and genetic responses of Salmonella Typhimurium to pH-shifts in an anaerobic continuous culture. | 2008 | Anaerobe | pmid:18061487 |
Narayanan N et al. | Isolation and culturing of a most common anaerobic ciliate, Metopus sp. | 2007 | Anaerobe | pmid:17223583 |
Zampa A et al. | Effects of different digestible carbohydrates on bile acid metabolism and SCFA production by human gut micro-flora grown in an in vitro semi-continuous culture. | 2004 | Anaerobe | pmid:16701496 |
Gutierrez-Bañuelos H et al. | Zoonotic bacterial populations, gut fermentation characteristics and methane production in feedlot steers during oral nitroethane treatment and after the feeding of an experimental chlorate product. | 2007 | Anaerobe | pmid:17208022 |
Vitali B et al. | An in vitro evaluation of the effect of probiotics and prebiotics on the metabolic profile of human microbiota. | 2012 | Anaerobe | pmid:22579985 |
Turunen K et al. | Impact of beta-glucan on the faecal microbiota of polypectomized patients: a pilot study. | 2011 | Anaerobe | pmid:21515398 |
Nasser Al-Shorgani NK et al. | Improvement of the butanol production selectivity and butanol to acetone ratio (B:A) by addition of electron carriers in the batch culture of a new local isolate of Clostridium acetobutylicum YM1. | 2015 | Anaerobe | pmid:26439644 |
Shen Q et al. | A comparative in vitro investigation into the effects of cooked meats on the human faecal microbiota. | 2010 | Anaerobe | pmid:20934523 |
Nazzaro F et al. | The prebiotic source influences the growth, biochemical features and survival under simulated gastrointestinal conditions of the probiotic Lactobacillus acidophilus. | 2012 | Anaerobe | pmid:22710413 |
D'Angelis CE et al. | Inhibiting effect of Dorstenia asaroides extracts on cariogenic properties of Streptococcus mutans. | 2012 | Anaerobe | pmid:22266301 |
Purwani EY et al. | Fermentation RS3 derived from sago and rice starch with Clostridium butyricum BCC B2571 or Eubacterium rectale DSM 17629. | 2012 | Anaerobe | pmid:21979490 |
Saengkerdsub S et al. | Effects of nitro compounds and feedstuffs on in vitro methane production in chicken cecal contents and rumen fluid. | 2006 | Anaerobe | pmid:16701620 |
Russell JB | Enrichment of fusobacteria from the rumen that can utilize lysine as an energy source for growth. | 2005 | Anaerobe | pmid:16701548 |
Miltko R et al. | Can fungal zoospores be the source of energy for the rumen protozoa Eudiplodinium maggii? | 2014 | Anaerobe | pmid:24012688 |
Allen-Vercoe E et al. | Anaerostipes hadrus comb. nov., a dominant species within the human colonic microbiota; reclassification of Eubacterium hadrum Moore et al. 1976. | 2012 | Anaerobe | pmid:22982042 |
Connolly ML et al. | In vitro evaluation of the microbiota modulation abilities of different sized whole oat grain flakes. | 2010 | Anaerobe | pmid:20624475 |
Yokoyama T et al. | Capillary electrophoretic separation between Fe(II) and Ni(II) precomplexed with 1,10-phenanthroline in a high concentration buffer of n-butyric acid/ n-butyrate and its application. | 2002 | Anal Bioanal Chem | pmid:12012197 |
Boersema PJ et al. | Hydrophilic interaction liquid chromatography (HILIC) in proteomics. | 2008 | Anal Bioanal Chem | pmid:18264818 |
Shao Y and Marriott P | Separation of positional isomers by the use of coupled shape-selective stationary phase columns. | 2003 | Anal Bioanal Chem | pmid:12638047 |
Raina R and Etter ML | Liquid chromatography with post-column reagent addition of ammonia in methanol coupled to negative ion electrospray ionization tandem mass spectrometry for determination of phenoxyacid herbicides and their degradation products in surface water. | 2010 | Anal Chem Insights | pmid:20212919 |
Khedr A et al. | High-performance liquid chromatographic method for determination of phenytoin in rabbits receiving sildenafil. | 2008 | Anal Chem Insights | pmid:19609390 |
El-Bagary RI et al. | Two chromatographic methods for the determination of some antimigraine drugs. | 2012 | Anal Chem Insights | pmid:22654488 |
Zounr RA et al. | Improved Gas Chromatographic Determination of Guanidino Compounds Using Isovaleroylacetone and Ethyl Chloroformate as Derivatizing Reagents. | 2016 | Anal Sci | pmid:26860556 |
Farajzadeh M and Mardani A | Analysis of residual solvents in ampicillin powder by headspace spectrophotometric method. | 2002 | Anal Sci | pmid:11874121 |
Hanford WC and Fishman WH | Measurement of biosynthetic rates and intracellular transit times for a cell-surface membrane glycoprotein, alkaline phosphatase in HeLa cells. | 1983 | Anal. Biochem. | pmid:6859522 |
Bandyopadhyay P and Joseph MT | Quantification of in vitro malodor generation by anionic surfactant-induced fluorescent sensor property of tryptophan. | 2010 | Anal. Biochem. | pmid:19818329 |
Bonge H et al. | Cytostar-T scintillating microplate assay for measurement of sodium-dependent bile acid uptake in transfected HEK-293 cells. | 2000 | Anal. Biochem. | pmid:10860504 |
Holtfrerich A et al. | High-performance liquid chromatography assay with fluorescence detection for the evaluation of inhibitors against human recombinant monoacylglycerol lipase. | 2010 | Anal. Biochem. | pmid:20015447 |
Fausnaugh JL et al. | High-performance hydrophobic interaction chromatography of proteins. | 1984 | Anal. Biochem. | pmid:6428267 |
Valle AB et al. | Colorimetric determination of succinic acid using yeast succinate dehydrogenase. | 1978 | Anal. Biochem. | pmid:9762145 |
Liu JT et al. | The investigation of recognition interaction between phenylboronate monolayer and glycated hemoglobin using surface plasmon resonance. | 2008 | Anal. Biochem. | pmid:18242160 |
Marshall S et al. | Enhanced expression of uridine diphosphate-N-acetylglucosaminyl transferase (OGT) in a stable, tetracycline-inducible HeLa cell line using histone deacetylase inhibitors: kinetics of cytosolic OGT accumulation and nuclear translocation. | 2003 | Anal. Biochem. | pmid:12871726 |
Knudsen J et al. | Quantitative extraction and separation from [1-14C]acetate and preparation for ratio gas chromatography of microgram amounts of a 14C-labeled mixture of butyrate and longer-chain-length fatty acids. | 1981 | Anal. Biochem. | pmid:7258625 |
Kim H et al. | Gas-phase analysis of trimethylamine, propionic and butyric acids, and sulfur compounds using solid-phase microextraction. | 2002 | Anal. Chem. | pmid:11924963 |
Borrás E et al. | Development of a gas chromatography-mass spectrometry method for the determination of pesticides in gaseous and particulate phases in the atmosphere. | 2011 | Anal. Chim. Acta | pmid:21704758 |
Ozyürek M et al. | Spectrophotometric determination of ascorbic acid by the modified CUPRAC method with extractive separation of flavonoids-La(III) complexes. | 2007 | Anal. Chim. Acta | pmid:17386797 |
Crespi F et al. | Melatonin, a hormone monitorable in vivo by voltammetry? | 1994 | Analyst | pmid:7527619 |
Zheng M et al. | Ferric ion immobilized on three-dimensional nanoporous gold films modified with self-assembled monolayers for electrochemical detection of hydrogen peroxide. | 2012 | Analyst | pmid:22223118 |
Tseng AS and Levin M | Transducing bioelectric signals into epigenetic pathways during tadpole tail regeneration. | 2012 | Anat Rec (Hoboken) | pmid:22933452 |
Madhukiran BL et al. | Antibacterial properties of leucas cephalotes (roth) spreng. Leaf. | 2002 | Anc Sci Life | pmid:22557062 |
Makala L et al. | FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors. | 2012 | Anemia | pmid:22655179 |
Kadam RU et al. | A glycopeptide dendrimer inhibitor of the galactose-specific lectin LecA and of Pseudomonas aeruginosa biofilms. | 2011 | Angew. Chem. Int. Ed. Engl. | pmid:21919164 |
Schäffer C et al. | A spherical 24 butyrate aggregate with a hydrophobic cavity in a capsule with flexible pores: confinement effects and uptake-release equilibria at elevated temperatures. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19774583 |
Liu K et al. | Dynamic monitoring of newly synthesized proteomes: up-regulation of myristoylated protein kinase A during butyric acid induced apoptosis. | 2011 | Angew. Chem. Int. Ed. Engl. | pmid:21678537 |
Yoshida Y et al. | Oral administration of Lactobacillus plantarum Lq80 and Megasphaera elsdenii iNP-001 induces efficient recovery from mucosal atrophy in the small and the large intestines of weaning piglets. | 2009 | Anim. Sci. J. | pmid:20163663 |
Iriki T et al. | Concentrations of ketone body and antidiuretic hormone in cerebrospinal fluid in response to the intra-ruminal administration of butyrate in suckling calves. | 2009 | Anim. Sci. J. | pmid:20163655 |
Sun H et al. | Effects of addition of Aspergillus oryzae culture and 2-hydroxyl-4-(methylthio) butanoic acid on milk performance and rumen fermentation of dairy cows. | 2017 | Anim. Sci. J. | pmid:27506446 |
Iriki T et al. | Plasma concentration of anti-diuretic hormone and urine volume in response to intraruminal administration of acetate, propinata and butyrate in suckling calves. | 2009 | Anim. Sci. J. | pmid:20163645 |
Wang C et al. | A survey of fermentation products and bacterial communities in corn silage produced in a bunker silo in China. | 2014 | Anim. Sci. J. | pmid:23638801 |
Liu Q et al. | Characteristics of isolated lactic acid bacteria and their effectiveness to improve stylo (Stylosanthes guianensis Sw.) silage quality at various temperatures. | 2012 | Anim. Sci. J. | pmid:22339693 |
Kamphayae S et al. | Effects of graded levels of liquid brewer's yeast on chemical composition and fermentation quality in cassava pulp and rice straw-based total mixed ration silage. | 2017 | Anim. Sci. J. | pmid:27611881 |
da Silva JS et al. | Nutritive value and fermentation quality of palisadegrass and stylo mixed silages. | 2018 | Anim. Sci. J. | pmid:28905506 |
Li P et al. | Effect of grape pomace on fermentation quality and aerobic stability of sweet sorghum silage. | 2017 | Anim. Sci. J. | pmid:28485116 |
Sato H and Shiogama Y | Fecal excretion of alcohols and organic anions in neonatal dairy calves. | 2009 | Anim. Sci. J. | pmid:20163587 |
Meenongyai W et al. | Effects of forage ensiling and ration fermentation on total mixed ration pH, ruminal fermentation and performance of growing Holstein-Zebu cross steers. | 2017 | Anim. Sci. J. | pmid:28370998 |
Wang J et al. | Comparative effects of sodium butyrate and flavors on feed intake of lactating sows and growth performance of piglets. | 2014 | Anim. Sci. J. | pmid:24773759 |
Sun YZ et al. | Rumen chemical and bacterial changes during stepwise adaptation to a high-concentrate diet in goats. | 2010 | Animal | pmid:22443874 |
He B et al. | Effects of sodium butyrate supplementation on reproductive performance and colostrum composition in gilts. | 2016 | Animal | pmid:27040131 |
Nozière P et al. | In vivo production and molar percentages of volatile fatty acids in the rumen: a quantitative review by an empirical approach. | 2011 | Animal | pmid:22445407 |
Lallès JP et al. | Impact of bioactive substances on the gastrointestinal tract and performance of weaned piglets: a review. | 2009 | Animal | pmid:22443548 |
Ferreira LS and Bittar CM | Performance and plasma metabolites of dairy calves fed starter containing sodium butyrate, calcium propionate or sodium monensin. | 2011 | Animal | pmid:22440769 |
Niwińska B et al. | Review: Exogenous butyrate: implications for the functional development of ruminal epithelium and calf performance. | 2017 | Animal | pmid:28193308 |
Bovera F et al. | Effect of mannanoligosaccharides supplementation on caecal microbial activity of rabbits. | 2010 | Animal | pmid:22444699 |
GarcÃa V et al. | Potential of carvacrol to modify in vitro rumen fermentation as compared with monensin. | 2007 | Animal | pmid:22444468 |
Gidenne T and Feugier A | Feed restriction strategy in the growing rabbit. 1. Impact on digestion, rate of passage and microbial activity. | 2009 | Animal | pmid:22444373 |