butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Jawed K et al. | Engineered Production of Short Chain Fatty Acid in Escherichia coli Using Fatty Acid Synthesis Pathway. | 2016 | PLoS ONE | pmid:27466817 |
Gargari G et al. | Consumption of a Bifidobacterium bifidum Strain for 4 Weeks Modulates Dominant Intestinal Bacterial Taxa and Fecal Butyrate in Healthy Adults. | 2016 | Appl. Environ. Microbiol. | pmid:27451450 |
Teixeira C et al. | Effects of variety and steeping conditions on some barley components associated with colonic health. | 2016 | J. Sci. Food Agric. | pmid:27450418 |
Zhou J et al. | Maternal sodium butyrate supplement elevates the lipolysis in adipose tissue and leads to lipid accumulation in offspring liver of weaning-age rats. | 2016 | Lipids Health Dis | pmid:27449927 |
Astakhova L et al. | Short Chain Fatty Acids (SCFA) Reprogram Gene Expression in Human Malignant Epithelial and Lymphoid Cells. | 2016 | PLoS ONE | pmid:27441625 |
Frycz BA et al. | Transcript level of AKR1C3 is down-regulated in gastric cancer. | 2016 | Biochem. Cell Biol. | pmid:27019068 |
Li H et al. | Sodium butyrate exerts neuroprotective effects by restoring the blood-brain barrier in traumatic brain injury mice. | 2016 | Brain Res. | pmid:27017959 |
Ortega JF et al. | Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein. | 2016 | Oncotarget | pmid:27013579 |
Sjöblom M et al. | Catalytic upgrading of butyric acid towards fine chemicals and biofuels. | 2016 | FEMS Microbiol. Lett. | pmid:26994015 |
Zhao Z et al. | Potential enhancement of direct interspecies electron transfer for syntrophic metabolism of propionate and butyrate with biochar in up-flow anaerobic sludge blanket reactors. | 2016 | Bioresour. Technol. | pmid:26967338 |
Han A et al. | Cellular Metabolism and Dose Reveal Carnitine-Dependent and -Independent Mechanisms of Butyrate Oxidation in Colorectal Cancer Cells. | 2016 | J. Cell. Physiol. | pmid:26661480 |
Tiwari P et al. | Preventive effects of butyric acid, nicotinamide, calcium glucarate alone or in combination during the 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis via modulation of K-Ras-PI3K-AKTpathway and associated micro RNAs. | 2016 | Biochimie | pmid:26655363 |
Valvassori SS et al. | Sodium butyrate has an antimanic effect and protects the brain against oxidative stress in an animal model of mania induced by ouabain. | 2016 | Psychiatry Res | pmid:26654753 |
Mátis G et al. | Feed-drug interaction of orally applied butyrate and phenobarbital on hepatic cytochrome P450 activity in chickens. | 2016 | J Anim Physiol Anim Nutr (Berl) | pmid:26614344 |
Luceri C et al. | Effect of butyrate enemas on gene expression profiles and endoscopic/histopathological scores of diverted colorectal mucosa: A randomized trial. | 2016 | Dig Liver Dis | pmid:26607831 |
Huang H et al. | Regulation of TWIK-related potassium channel-1 (Trek1) restitutes intestinal epithelial barrier function. | 2016 | Cell. Mol. Immunol. | pmid:25683610 |
Neis EP et al. | Effects of Liver Resection on Hepatic Short-Chain Fatty Acid Metabolism in Humans. | 2016 | PLoS ONE | pmid:27835668 |
Khairy H et al. | The NADH:flavin oxidoreductase Nox from Rhodococcus erythropolis MI2 is the key enzyme of 4,4'-dithiodibutyric acid degradation. | 2016 | Lett. Appl. Microbiol. | pmid:27564089 |
Kong X et al. | Inhibiting excessive acidification using zero-valent iron in anaerobic digestion of food waste at high organic load rates. | 2016 | Bioresour. Technol. | pmid:26998799 |
Jones RJ et al. | Removal and recovery of inhibitory volatile fatty acids from mixed acid fermentations by conventional electrodialysis. | 2015 | Bioresour. Technol. | pmid:25898090 |
Tian H et al. | Anaerobic co-digestion of kitchen waste and pig manure with different mixing ratios. | 2015 | J. Biosci. Bioeng. | pmid:25617184 |
Zheng XT et al. | Sodium butyrate down-regulates tristetraprolin-mediated cyclin B1 expression independent of the formation of processing bodies. | 2015 | Int. J. Biochem. Cell Biol. | pmid:26555753 |
Deng Y et al. | Driving carbon flux through exogenous butyryl-CoA: Acetate CoA-transferase to produce butyric acid at high titer in Thermobifida fusca. | 2015 | J. Biotechnol. | pmid:26535965 |
Durlak M et al. | A Novel High-Content Immunofluorescence Assay as a Tool to Identify at the Single Cell Level γ-Globin Inducing Compounds. | 2015 | PLoS ONE | pmid:26509275 |
Fomina-Yadlin D et al. | Transcriptome analysis of a CHO cell line expressing a recombinant therapeutic protein treated with inducers of protein expression. | 2015 | J. Biotechnol. | pmid:26325199 |
Patman G | Gut microbiota: Lactobacillus acidophilus opens the door to butyrate. | 2015 | Nat Rev Gastroenterol Hepatol | pmid:26323876 |
Desai VH et al. | Receptor-Guided De Novo Design of Dengue Envelope Protein Inhibitors. | 2015 | Appl. Biochem. Biotechnol. | pmid:26299376 |
Kumar A et al. | Lactobacillus acidophilus counteracts enteropathogenic E. coli-induced inhibition of butyrate uptake in intestinal epithelial cells. | 2015 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:26272259 |
Kumar P et al. | Differential Effects of Sodium Butyrate and Lithium Chloride on Rhesus Monkey Trophoblast Differentiation. | 2015 | PLoS ONE | pmid:26266541 |
Li L et al. | Increased Butyrate Production During Long-Term Fermentation of In Vitro-Digested High Amylose Cornstarch Residues with Human Feces. | 2015 | J. Food Sci. | pmid:26256258 |
Shang HM et al. | Effects of dietary polysaccharides from the submerged fermentation concentrate of Hericium caput-medusae (Bull.:Fr.) Pers. on fat deposition in broilers. | 2015 | J. Sci. Food Agric. | pmid:24771556 |
Levy AW et al. | Effect of feeding an encapsulated source of butyric acid (ButiPEARL) on the performance of male Cobb broilers reared to 42 d of age. | 2015 | Poult. Sci. | pmid:26015588 |
Liu H et al. | Post-occlusion administration of sodium butyrate attenuates cognitive impairment in a rat model of chronic cerebral hypoperfusion. | 2015 | Pharmacol. Biochem. Behav. | pmid:26013850 |
Chaturvedi K et al. | Oral insulin delivery using deoxycholic acid conjugated PEGylated polyhydroxybutyrate co-polymeric nanoparticles. | 2015 | Nanomedicine (Lond) | pmid:26008194 |
Theparambil SM et al. | Reversed electrogenic sodium bicarbonate cotransporter 1 is the major acid loader during recovery from cytosolic alkalosis in mouse cortical astrocytes. | 2015 | J. Physiol. (Lond.) | pmid:25990710 |
Chou YC et al. | Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells. | 2015 | Mol. Cell. Biol. | pmid:25986606 |
Gurav A et al. | Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer under low-fibre dietary conditions. | 2015 | Biochem. J. | pmid:25984582 |
Chen JH and Chou CC | Acrylamide inhibits cellular differentiation of human neuroblastoma and glioblastoma cells. | 2015 | Food Chem. Toxicol. | pmid:25959841 |
Conlon MA et al. | Lowering of large bowel butyrate levels in healthy populations is unlikely to be beneficial. | 2015 | J. Nutr. | pmid:25934666 |
Li L et al. | Histone deacetylase inhibitor sodium butyrate suppresses DNA double strand break repair induced by etoposide more effectively in MCF-7 cells than in HEK293 cells. | 2015 | BMC Biochem. | pmid:25592494 |
Henagan TM et al. | Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning. | 2015 | Br. J. Pharmacol. | pmid:25559882 |
Weaver EM et al. | Regulation of T-type calcium channel expression by sodium butyrate in prostate cancer cells. | 2015 | Eur. J. Pharmacol. | pmid:25557765 |
Arai T et al. | Actinomyces naeslundii GroEL-dependent initial attachment and biofilm formation in a flow cell system. | 2015 | J. Microbiol. Methods | pmid:25555820 |
Huang C et al. | Evaluating the possibility of using acetone-butanol-ethanol (ABE) fermentation wastewater for bacterial cellulose production by Gluconacetobacter xylinus. | 2015 | Lett. Appl. Microbiol. | pmid:25615895 |
Barichello T et al. | Sodium Butyrate Prevents Memory Impairment by Re-establishing BDNF and GDNF Expression in Experimental Pneumococcal Meningitis. | 2015 | Mol. Neurobiol. | pmid:25284351 |
Mátis G et al. | Effects of oral butyrate application on insulin signaling in various tissues of chickens. | 2015 | Domest. Anim. Endocrinol. | pmid:25240231 |
Esteras N et al. | G1/S Cell Cycle Checkpoint Dysfunction in Lymphoblasts from Sporadic Parkinson's Disease Patients. | 2015 | Mol. Neurobiol. | pmid:25182869 |
Cottier F et al. | MIG1 Regulates Resistance of Candida albicans against the Fungistatic Effect of Weak Organic Acids. | 2015 | Eukaryotic Cell | pmid:26297702 |
Dengler F et al. | Both butyrate incubation and hypoxia upregulate genes involved in the ruminal transport of SCFA and their metabolites. | 2015 | J Anim Physiol Anim Nutr (Berl) | pmid:24804847 |
Chen F et al. | Unusual effects of monocarboxylic acids on the structure and on the transport and mechanical properties of chitosan films. | 2015 | Carbohydr Polym | pmid:26256366 |