butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Anisimová E et al. | Chemically purified serum factor can induce both Epstein-Barr virus antigen synthesis and cell differentiation. | 1987 | Arch. Virol. | pmid:3034214 |
Liang CY et al. | High efficiency gene transfer into mammalian kidney cells using baculovirus vectors. | 2004 | Arch. Virol. | pmid:14689275 |
Li B et al. | Expression of butyrate response factor 1 in HTLV-1-transformed cells and its transactivation by tax protein. | 2003 | Arch. Virol. | pmid:14505090 |
Adolf GR et al. | Spontaneous production of alpha- and beta-interferon in human lymphoblastoid and lymphoma cell lines. | 1982 | Arch. Virol. | pmid:6180703 |
Anisimová E et al. | Effects of n-butyrate and phorbol ester (TPA) on induction of Epstein-Barr virus antigens and cell differentiation. | 1984 | Arch. Virol. | pmid:6089703 |
Asai S et al. | Ultrastructural studies on cell fusion induced by Epstein-Barr virus or N-butyrate and 12-O-tetradecanoylphorbol-13-acetate. Brief report. | 1985 | Arch. Virol. | pmid:2998304 |
Fujita R et al. | An HDAC inhibitor increases AcMNPV gene expression in mammalian cells. | 2010 | Arch. Virol. | pmid:20186445 |
Horz HP and Conrads G | The discussion goes on: What is the role of Euryarchaeota in humans? | 2010 | Archaea | pmid:21253553 |
Ranganna K et al. | Sodium butyrate inhibits platelet-derived growth factor-induced proliferation of vascular smooth muscle cells. | 1995 | Arterioscler. Thromb. Vasc. Biol. | pmid:7489253 |
Grabiec AM et al. | Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on? | 2008 | Arthritis Res. Ther. | pmid:18983693 |
Kawabata T et al. | Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis. | 2010 | Arthritis Res. Ther. | pmid:20609223 |
Mort JS | Histone deacetylases--a new target for suppression of cartilage degradation? | 2005 | Arthritis Res. Ther. | pmid:15987498 |
de Grauw JC et al. | A targeted lipidomics approach to the study of eicosanoid release in synovial joints. | 2011 | Arthritis Res. Ther. | pmid:21794148 |
Young DA et al. | Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption. | 2005 | Arthritis Res. Ther. | pmid:15899037 |
Fukae J et al. | Butyrate suppresses tumor necrosis factor alpha production by regulating specific messenger RNA degradation mediated through a cis-acting AU-rich element. | 2005 | Arthritis Rheum. | pmid:16142751 |
Tayebi B et al. | Modulation of microRNAs expression in hematopoietic stem cells treated with sodium butyrate in inducing fetal hemoglobin expression. | 2017 | Artif Cells Nanomed Biotechnol | pmid:26837891 |
AteÅŸ S et al. | Enhanced ethyl butyrate production using immobilized lipase. | 2013 | Artif Cells Nanomed Biotechnol | pmid:23305408 |
Honecker VH and Coper H | [Stability of amphetaminil. 1. In-vitro studies]. | 1975 | Arzneimittelforschung | pmid:1174051 |
Celasco G et al. | Pharmacological profile of 9,11-dehydrocortexolone 17alpha-butyrate (CB-03-04), a new androgen antagonist with antigonadotropic activity. | 2005 | Arzneimittelforschung | pmid:16294504 |
Nozawa S et al. | In vitro and in vivo induction of squamous cell carcinoma antigen (SCC) in a uterine cervical cancer cell line (SKG-IIIa) with peplomycin and sodium butyrate. | 1990 | Asia Oceania J Obstet Gynaecol | pmid:1696099 |
Patten GS et al. | Effects of convenience rice congee supplemented diets on guinea pig whole animal and gut growth, caecal digesta SCFA and in vitro ileal contractility. | 2004 | Asia Pac J Clin Nutr | pmid:15003921 |
Okoye TC et al. | Evaluation of the acute and sub acute toxicity of Annona senegalensis root bark extracts. | 2012 | Asian Pac J Trop Med | pmid:22449518 |
Priyashree S et al. | Bronchodilatory and mast cell stabilising activity of Cressa cretica L.: evaluation through in vivo and in vitro experimental models. | 2012 | Asian Pac J Trop Med | pmid:22305781 |
Ettebong EO et al. | In vivo antiplasmodial activities of ethanolic extract and fractions of Eleucine indica. | 2012 | Asian Pac J Trop Med | pmid:22805716 |
Chinasa EC et al. | Evaluation of anti-inflammatory property of the leaves of Sansevieria liberica ger. and labr. (fam: Dracaenaceae). | 2011 | Asian Pac J Trop Med | pmid:22014734 |
Nabandith V et al. | Inhibitory effects of crude alpha-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat. | Asian Pac. J. Cancer Prev. | pmid:15546251 | |
Gandhi GK et al. | Hyperglycaemia and diabetes impair gap junctional communication among astrocytes. | 2010 | ASN Neuro | pmid:20396375 |
Furukawa M et al. | Epstein-Barr virus early antigen induction in nasopharyngeal hybrid cells by Chinese medicinal herbs. | 1986 | Auris Nasus Larynx | pmid:3028348 |
Furukawa M and Umeda R | Inhibitory effect of retinoid (E5166) on cell growth and suppressive effect on Epstein-Barr virus early-antigen induction by n-butyrate in nasopharyngeal hybrid cells. | 1987 | Auris Nasus Larynx | pmid:2820366 |
Arcus AC et al. | Studies with the autotransplanted ovine pancreas: glucagon and insulin secretion. | 1976 | Aust. J. Biol. Sci. | pmid:791227 |
Packer EL et al. | Rumen fermentation and liveweight gain in beef cattle treated with monensin and grazing lush forage. | 2011 | Aust. Vet. J. | pmid:21864305 |
Pedersen G et al. | Cultures of human colonic epithelial cells isolated from endoscopical biopsies from patients with inflammatory bowel disease. Effect of IFNgamma, TNFalpha and IL-1beta on viability, butyrate oxidation and IL-8 secretion. | 2000 | Autoimmunity | pmid:11191284 |
Ping W et al. | Baculovirus-mediated gene expression in chicken primary cells. | 2006 | Avian Dis. | pmid:16617983 |
Henriksen M et al. | Evaluation of PCR and DNA sequencing for direct detection of Clostridium perfringens in the intestinal tract of broilers. | 2009 | Avian Dis. | pmid:19848086 |
Van Immerseel F et al. | Interactions of butyric acid- and acetic acid-treated Salmonella with chicken primary cecal epithelial cells in vitro. | 2004 Apr-Jun | Avian Dis. | pmid:15283426 |
Timbermont L et al. | Control of Clostridium perfringens-induced necrotic enteritis in broilers by target-released butyric acid, fatty acids and essential oils. | 2010 | Avian Pathol. | pmid:20390546 |
Van Deun K et al. | Short-chain fatty acids and L-lactate as feed additives to control Campylobacter jejuni infections in broilers. | 2008 | Avian Pathol. | pmid:18622853 |
Ishihara K et al. | Identification of urinary biomarkers useful for distinguishing a difference in mechanism of toxicity in rat model of cholestasis. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19486331 |
Podzuweit T et al. | Cyclic AMP mediated arrhythmias induced in the ischaemic pig heart. | 1981 Jul-Aug | Basic Res. Cardiol. | pmid:6116488 |
Moretti M et al. | Behavioral and neurochemical effects of sodium butyrate in an animal model of mania. | 2011 | Behav Pharmacol | pmid:21989497 |
Resende WR et al. | Effects of sodium butyrate in animal models of mania and depression: implications as a new mood stabilizer. | 2013 | Behav Pharmacol | pmid:23994816 |
Petry FS et al. | Histone deacetylase inhibition prevents the impairing effects of hippocampal gastrin-releasing peptide receptor antagonism on memory consolidation and extinction. | 2016 | Behav. Brain Res. | pmid:27025446 |
Horii Y et al. | Exposure to TMT odor affects adrenal sympathetic nerve activity and behavioral consequences in rats. | 2010 | Behav. Brain Res. | pmid:20595033 |
Sharma S et al. | Beneficial effects of sodium butyrate in 6-OHDA induced neurotoxicity and behavioral abnormalities: Modulation of histone deacetylase activity. | 2015 | Behav. Brain Res. | pmid:26048426 |
Yang J et al. | Inhibition of nuclear factor-κB impairs reconsolidation of morphine reward memory in rats. | 2011 | Behav. Brain Res. | pmid:20816896 |
Ayers LW et al. | Freezing to the predator odor 2,4,5 dihydro 2,5 trimethylthiazoline (TMT) is disrupted by olfactory bulb removal but not trigeminal deafferentation. | 2013 | Behav. Brain Res. | pmid:23831303 |
Kalda A et al. | Histone deacetylase inhibitors modulates the induction and expression of amphetamine-induced behavioral sensitization partially through an associated learning of the environment in mice. | 2007 | Behav. Brain Res. | pmid:17477979 |
Reolon GK et al. | Posttraining systemic administration of the histone deacetylase inhibitor sodium butyrate ameliorates aging-related memory decline in rats. | 2011 | Behav. Brain Res. | pmid:21421011 |
Zhu H et al. | Antidepressant-like effects of sodium butyrate in combination with estrogen in rat forced swimming test: involvement of 5-HT(1A) receptors. | 2009 | Behav. Brain Res. | pmid:18817816 |
Watanabe T et al. | Green odor and depressive-like state in rats: toward an evidence-based alternative medicine? | 2011 | Behav. Brain Res. | pmid:21684308 |
Wallace KJ and Rosen JB | Predator odor as an unconditioned fear stimulus in rats: elicitation of freezing by trimethylthiazoline, a component of fox feces. | 2000 | Behav. Neurosci. | pmid:11085605 |
Lattal KM et al. | Systemic or intrahippocampal delivery of histone deacetylase inhibitors facilitates fear extinction. | 2007 | Behav. Neurosci. | pmid:17907845 |
Zhu Y et al. | [In vitro study about the inhibitory effect of CDAII in combination with sodium butyrate on breast cancer cells]. | 2007 | Beijing Da Xue Xue Bao | pmid:17940563 |
Havenaar R | Intestinal health functions of colonic microbial metabolites: a review. | 2011 | Benef Microbes | pmid:21840809 |
Roelofsen H et al. | The interaction of short-chain fatty acids with adipose tissue: relevance for prevention of type 2 diabetes. | 2010 | Benef Microbes | pmid:21831781 |
Bird AR et al. | Resistant starch, large bowel fermentation and a broader perspective of prebiotics and probiotics. | 2010 | Benef Microbes | pmid:21831780 |
Binsl TW et al. | Measuring non-steady-state metabolic fluxes in starch-converting faecal microbiota in vitro. | 2010 | Benef Microbes | pmid:21831778 |
Mäkeläinen H et al. | Xylo-oligosaccharides enhance the growth of bifidobacteria and Bifidobacterium lactis in a simulated colon model. | 2010 | Benef Microbes | pmid:21831753 |
Mäkivuokko H et al. | Synbiotic effects of lactitol and Lactobacillus acidophilus NCFM™ in a semi-continuous colon fermentation model. | 2010 | Benef Microbes | pmid:21840801 |
Fernando WM et al. | Diets supplemented with chickpea or its main oligosaccharide component raffinose modify faecal microbial composition in healthy adults. | 2010 | Benef Microbes | pmid:21831757 |
Fürll M et al. | [Hormonal reactions in fattening bulls and cows during a three-week butyric acid exposure]. | 1993 | Berl. Munch. Tierarztl. Wochenschr. | pmid:8267563 |
Fürll M et al. | [Effect of a three-week butyric acid exposure on the mineral metabolism and the skeletal system in cattle]. | 1993 | Berl. Munch. Tierarztl. Wochenschr. | pmid:8267564 |
Ichikawa N et al. | Production, purification and characterization of the plasminogen activator in teratocarcinoma stem cells induced with sodium butyrate. | 1984 | Biken J | pmid:6443174 |
Nikolić N et al. | Overexpression of PGC-1α increases fatty acid oxidative capacity of human skeletal muscle cells. | 2012 | Biochem Res Int | pmid:21904680 |
Iwalokun BA et al. | Evaluation of the Possible Mechanisms of Antihypertensive Activity of Loranthus micranthus: An African Mistletoe. | 2011 | Biochem Res Int | pmid:21918720 |
Désilets A et al. | Inhibition by deacetylase inhibitors of IL-1-dependent induction of haptoglobin involves CCAAT/Enhancer-binding protein isoforms in intestinal epithelial cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:11027530 |
Filippovich I et al. | Butyrate induced apoptosis in lymphoid cells preceded by transient over-expression of HSP70 mRNA. | 1994 | Biochem. Biophys. Res. Commun. | pmid:7904816 |
Shimizu A et al. | CyclinG contributes to G2/M arrest of cells in response to DNA damage. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9464250 |
Gaudier E et al. | Butyrate regulation of glycosylation-related gene expression: evidence for galectin-1 upregulation in human intestinal epithelial goblet cells. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15541394 |
Otaka M et al. | Antibody-mediated targeting of differentiation inducers to tumor cells: inhibition of colonic cancer cell growth in vitro and in vivo. A preliminary note. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2912449 |
Reppe S et al. | Butyrate response factor 1 is regulated by parathyroid hormone and bone morphogenetic protein-2 in osteoblastic cells. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15465005 |
Lallemand F et al. | Direct inhibition of the expression of cyclin D1 gene by sodium butyrate. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8954100 |
Bahn RS et al. | n-Butyrate increases c-erb A oncogene expression in human colon fibroblasts. | 1988 | Biochem. Biophys. Res. Commun. | pmid:2447891 |
Oster T et al. | Induction of recombinant human gamma-glutamyl transferase by sodium butyrate in transfected V79 and CHO Chinese hamster cells. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8099285 |
Kitajima M et al. | Characterization of baculovirus Autographa californica multiple nuclear polyhedrosis virus infection in mammalian cells. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16545777 |
Steiner E et al. | SP-transcription factors are involved in basal MVP promoter activity and its stimulation by HDAC inhibitors. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15047174 |
TaÅŸtan Bishop AO and Sewell T | A new approach to possible substrate binding mechanisms for nitrile hydratase. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16540090 |
Cuff MA and Shirazi-Beechey SP | The human monocarboxylate transporter, MCT1: genomic organization and promoter analysis. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11944921 |
Akiba Y et al. | Histone deacetylase inhibitors de-repress tyrosine hydroxylase expression in the olfactory bulb and rostral migratory stream. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20170631 |
Wiegandt H et al. | Retinoic acid alters the metabolic 3H-labelling of glycosphingolipids. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3032172 |
Siavoshian S et al. | Butyrate stimulates cyclin D and p21 and inhibits cyclin-dependent kinase 2 expression in HT-29 colonic epithelial cells. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9125124 |
Ide Y et al. | Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16434023 |
Ogawa H et al. | Butyrate modulates gene and protein expression in human intestinal endothelial cells. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12963019 |
Zgouras D et al. | Modulation of angiogenesis-related protein synthesis by valproic acid. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15033455 |
McMillan L et al. | Bile acids reduce the apoptosis-inducing effects of sodium butyrate on human colon adenoma (AA/C1) cells: implications for colon carcinogenesis. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10873561 |
Calabresse C et al. | Butyric acid and its monosaccharide ester induce apoptosis in the HL-60 cell line. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8363611 |
Wei P et al. | Reversible immortalization of Nestin-positive precursor cells from pancreas and differentiation into insulin-secreting cells. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22266322 |
Xiao H et al. | Sodium butyrate induces NIH3T3 cells to senescence-like state and enhances promoter activity of p21WAF/CIP1 in p53-independent manner. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9268733 |
Lee SK et al. | Cellular differentiation-induced attenuation of LPS response in HT-29 cells is related to the down-regulation of TLR4 expression. | 2005 | Biochem. Biophys. Res. Commun. | pmid:16202385 |
Aung CS et al. | Plasma membrane Ca2+-ATPase expression during colon cancer cell line differentiation. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17321497 |
Jahangeer S et al. | beta-Adrenergic receptor induction in HeLa cells: synergistic effect of 5-azacytidine and butyrate. | 1982 | Biochem. Biophys. Res. Commun. | pmid:6185119 |
Yoneda T et al. | Sodium butyrate (SB) augments the effects of 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) on neoplastic and osteoblastic phenotype in clonal rat osteosarcoma cells. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6588971 |
Rabelo FL et al. | Inhibition of ERK1/2 and CREB phosphorylation by caspase-dependent mechanism enhances apoptosis in a fibrosarcoma cell line treated with butyrate. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12670506 |
Ramirez ML et al. | Chlorambucil-induced changes in chromatin methylation and their modulation by sodium butyrate. | 1982 | Biochem. Biophys. Res. Commun. | pmid:7181918 |
Nilsson NE et al. | Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12684041 |
Rabelo FL et al. | Apoptosis induced by butyrate is independent of Jak/STAT signaling in a fibrosarcoma cell line. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12589807 |
Terakawa M et al. | Eosinophil migration induced by mast cell chymase is mediated by extracellular signal-regulated kinase pathway. | 2005 | Biochem. Biophys. Res. Commun. | pmid:15919053 |
Diakos C et al. | n-Butyrate inhibits Jun NH(2)-terminal kinase activation and cytokine transcription in mast cells. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16949031 |
Bergann T et al. | A colonic mineralocorticoid receptor cell model expressing epithelial Na+ channels. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19275887 |
Zhao Y et al. | Histone acetylation regulates both transcription initiation and elongation of hsp22 gene in Drosophila. | 2005 | Biochem. Biophys. Res. Commun. | pmid:15607742 |