butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Glioma D005910 112 associated lipids
Weight Gain D015430 101 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Seizures D012640 87 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Alzheimer Disease D000544 76 associated lipids
Leukemia D007938 74 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Melanoma D008545 69 associated lipids
Colitis D003092 69 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Authors Title Published Journal PubMed Link
Hamasaki Y et al. Butyric acid enhances cyclooxygenase activity in rat basophilic leukemia 2H3 cells. 1988 Nippon Ketsueki Gakkai Zasshi pmid:3144111
Clouet PM and Bourre JM Ketone body utilization for lipid synthesis in the murine sciatic nerve: alterations in the dysmyelinating trembler mutant. 1988 J. Neurochem. pmid:3361304
Salam S Inhibitor(S) of prostaglandin endoperoxide synthase and lipoxygenase activity in extracts of barley. 1988 Pak J Pharm Sci pmid:16414615
Almlöf I et al. Induction of basophilic differentiation in the human basophilic cell line KU812. 1988 Scand. J. Immunol. pmid:2973655
Zhu XZ and Chuang DM Differential regulation by butyrate and dibutyryl cyclic AMP of delta-opioid, alpha 2-adrenergic, and muscarinic cholinergic receptors in NCB-20 cells. 1988 J. Neurochem. pmid:2826684
Nishimura J et al. Regulation of biosynthesis and phosphorylation of P210bcr/abl protein during differentiation induction of K 562 cells. 1988 Leuk. Res. pmid:2464113
Fischkoff SA Graded increase in probability of eosinophilic differentiation of HL-60 promyelocytic leukemia cells induced by culture under alkaline conditions. 1988 Leuk. Res. pmid:3184985
Takano M et al. Sodium butyrate increases glucose transporter expression in LLC-PK1 cells. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3186708
Januszewicz E et al. Butyric acid: inhibition of non-leukemic and chronic myeloid leukemia granulocyte macrophage clonal growth. 1988 Med Oncol Tumor Pharmacother pmid:3193830
Rhoads DB et al. Evidence for expression of the facilitated glucose transporter in rat hepatocytes. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3194405
Brass EP and Beyerinck RA Effects of propionate and carnitine on the hepatic oxidation of short- and medium-chain-length fatty acids. 1988 Biochem. J. pmid:3134008
Schönfeld P et al. On the mechanism of the so-called uncoupling effect of medium- and short-chain fatty acids. 1988 Biochim. Biophys. Acta pmid:3196710
Chatham J et al. Inhibition of glucose phosphorylation by fatty acids in the perfused rat heart. 1988 FEBS Lett. pmid:3169268
Albertini S et al. The in vitro porcine brain tubulin assembly assay: effects of a genotoxic carcinogen (aflatoxin B1), eight tumor promoters and nine miscellaneous substances. 1988 Mutat. Res. pmid:3173378
Gressner AM and Haarmann R Effect of n-butyrate on the synthesis of sulfated glycosaminoglycans and hyaluronate by rat liver fat-storing cells (Ito cells). 1988 Biochem. Pharmacol. pmid:3178890
Vernia P et al. Organic anions and the diarrhea of inflammatory bowel disease. 1988 Dig. Dis. Sci. pmid:3180970
Leith JT Potentiation of X ray sensitivity by combinations of sodium butyrate and buthionine sulfoximine. 1988 Int. J. Radiat. Oncol. Biol. Phys. pmid:3182335
Chang CC et al. Effects of sodium butyrate on the secretion of beta-2-microglobulin and calcitonin in a human ovarian cancer cell line OC-3-VGH. 1988 Zhonghua Yi Xue Za Zhi (Taipei) pmid:3066455
Campbell M and Chader GJ Retinoblastoma cells in tissue culture. 1988 Ophthalmic Paediatr Genet pmid:3068600
Ohwaki K [High carboxylic acid level in the gingival crevicular fluid (GCF) of the patients with advanced periodontal disease]. 1988 Nihon Shishubyo Gakkai Kaishi pmid:3078007
Herold KM and Rothberg PG Evidence for a labile intermediate in the butyrate induced reduction of the level of c-myc RNA in SW837 rectal carcinoma cells. 1988 Oncogene pmid:3078950
Bidet M et al. Role of monocarboxylic acid transport in intracellular pH regulation of isolated proximal cells. 1988 Biochim. Biophys. Acta pmid:3342236
Davidson AM and Halestrap AP Inorganic pyrophosphate is located primarily in the mitochondria of the hepatocyte and increases in parallel with the decrease in light-scattering induced by gluconeogenic hormones, butyrate and ionophore A23187. 1988 Biochem. J. pmid:2845949
Yusta B et al. Comparison of the effects of forskolin and dibutyryl cyclic AMP in neuroblastoma cells: evidence that some of the actions of dibutyryl cyclic AMP are mediated by butyrate. 1988 J. Neurochem. pmid:2846786
Yokochi T et al. Effect of activation of the Epstein-Barr virus genome on expression of B cell differentiation antigens of Burkitt's lymphoma lines. 1988 Microbiol. Immunol. pmid:2850450
Morise T et al. Biological activity of partially purified digitalis-like substance and Na-K-ATPase inhibitor in rats. 1988 Jpn. Circ. J. pmid:2852264
Li JS and Cheng YC Interaction of Epstein-Barr virus DNA polymerase with aphidicolin, phosphonoformate and 5'-GMP. 1988 Virus Genes pmid:2852412
Prasad S and Thakur MK Age-dependent effects of sodium butyrate and hydrocortisone on acetylation of high mobility group proteins of rat liver. 1988 Biochem. Int. pmid:3365268
Niles RM et al. The effect of sodium butyrate and retinoic acid on growth and CEA production in a series of human colorectal tumor cell lines representing different states of differentiation. 1988 Cancer Invest. pmid:3365571
Leith JT Modification of the hypoxic fraction of a xenografted human colon tumor by differentiation-inducing agents. 1988 J. Natl. Cancer Inst. pmid:3367384
Cattini PA et al. Effect of butyrate on thyroid hormone-mediated gene expression in rat pituitary tumour cells. 1988 Mol. Cell. Endocrinol. pmid:3371552
Leith JT et al. Changes in X-ray sensitivity and glutathione content of human colon tumor cells after exposure to the differentiation-inducing agent sodium butyrate. 1988 Radiat. Res. pmid:3375444
Joshi SS et al. Effects of differentiation inducing chemicals on in vivo malignancy and NK susceptibility of metastatic lymphoma cells. 1988 Cancer Detect. Prev. pmid:3390859
Kamech N and Seif R Evidence for new cellular proteins which may negatively control DNA replication or cell growth in rat 3T3 fibroblasts. 1988 Exp. Cell Res. pmid:3391246
Virtanen I et al. Expression of intermediate filaments and synaptophysin show neuronal properties and lack of glial characteristics in Y79 retinoblastoma cells. 1988 Lab. Invest. pmid:3141718
Lacroix J et al. In vitro and in vivo activity of 1-aryl-3-(2-chloroethyl) urea derivatives as new antineoplastic agents. 1988 Jul-Aug Anticancer Res. pmid:3052247
Tocco DJ et al. Disposition and metabolism of sodium 4-[(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl)sulfonyl]-gamma -oxobenzenebutanoate in rats and dogs. 1988 Sep-Oct Drug Metab. Dispos. pmid:2906591
Tocco DJ et al. The physiological disposition of aerosolized 4-[(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl)sulfonyl]-gamma -oxobenzenebutanoate (L-648,051) in rats. 1988 Sep-Oct Drug Metab. Dispos. pmid:2906592
Corfield AP et al. Selection of radioactive precursors for metabolic labelling of mucus glycoproteins. 1989 Biochem. Soc. Trans. pmid:2628065
Pramanik SK and Bag J Expression of muscle-specific proteins is necessary to regulate translation of the mRNA for a 40-kDa housekeeping polypeptide in rat L6 cells. 1989 Eur. J. Biochem. pmid:2473901
Myers DE et al. The effects of aromatic and aliphatic maleimide crosslinkers on anti-CD5 ricin immunotoxins. 1989 J. Immunol. Methods pmid:2474026
Arock M et al. Histamine-releasing activity of endogenous peptides on mast cells derived from different sites and species. 1989 Int. Arch. Allergy Appl. Immunol. pmid:2474510
Mossman SP et al. The effects of 5-azacytidine, 12-O-tetradecanoylphorbol 13-acetate and sodium n-butyrate on reactivation of alphaherpesvirus saimiri from explant cultures of latently infected rabbit dorsal root ganglia. 1989 J. Gen. Virol. pmid:2476529
Foss FM et al. Alterations in the expression of pp60c-src and p56lck associated with butyrate-induced differentiation of human colon carcinoma cells. 1989 Oncogene Res. pmid:2476706
Brantschen S et al. Factors influencing proliferation and histamine content of cultured human bone marrow cells. 1989 Immunobiology pmid:2477328
Alberts P Effects of N6,2'-O-dibutyryladenosine 3',5'-cyclic monophosphate, adenosine, and of oxotremorine and 3-isobutyl-1-methylxanthine on the electrically evoked [3H]acetylcholine secretion in the guinea-pig ileum myenteric plexus. 1989 Acta Physiol. Scand. pmid:2481381
Kubin T et al. Inhibition of DNA synthesis of adult rat hepatocytes in primary culture by dibutyrylcytidine 3', 5'-cyclic monophosphate. 1989 Cell Biol. Int. Rep. pmid:2481569
Clarke J et al. A comparison of the effects of various stimulatory agents on t-PA secretion by normal and malignant cell lines. 1989 Cell Biochem. Funct. pmid:2481573
Constantoulakis P et al. Butyrate stimulates HbF in adult baboons. 1989 Prog. Clin. Biol. Res. pmid:2482502
Kone P et al. Effect of the combination of monensin and isoacids on rumen fermentation in vitro. 1989 J. Dairy Sci. pmid:2600235
Schulz M et al. Regulation by dibutyryl cyclic AMP of carnosine synthesis in astroglia-rich primary cultures kept in serum-free medium. 1989 J. Neurochem. pmid:2462017
Nackerdien Z et al. Chromatin decondensed by acetylation shows an elevated radiation response. 1989 Radiat. Res. pmid:2922469
Matsui-Yuasa I et al. Two mechanisms of spermidine/spermine N1-acetyltransferase-induction. 1989 Arch. Biochem. Biophys. pmid:2463788
Casper D and Davies P Stimulation of choline acetyltransferase activity by retinoic acid and sodium butyrate in a cultured human neuroblastoma. 1989 Brain Res. pmid:2924123
Cox GS and Park KH Modulation of glycoprotein hormone alpha-subunit levels, alkaline phosphatase activity, and DNA replication by antimetabolites in HeLa cultures. 1989 Arch. Biochem. Biophys. pmid:2463791
Casper D and Davies P Mechanism of activation of choline acetyltransferase in a human neuroblastoma cell line. 1989 Brain Res. pmid:2924124
Shimamura A and Worcel A The assembly of regularly spaced nucleosomes in the Xenopus oocyte S-150 extract is accompanied by deacetylation of histone H4. 1989 J. Biol. Chem. pmid:2760072
Chatham JC et al. The metabolic consequences of hydroperoxide perfusion on the isolated rat heart. 1989 Eur. J. Biochem. pmid:2806248
Aizawa K et al. Placental alkaline phosphatase-like isoenzymes produced by human gastric cancer cells. 1989 Acta Pathol. Jpn. pmid:2686348
Tanaka Y et al. Enhancement of butyrate-induced differentiation of HT-29 human colon carcinoma cells by 1,25-dihydroxyvitamin D3. 1989 Biochem. Pharmacol. pmid:2688649
Flatow U et al. Characterization and tumorigenicity of a butyrate-adapted T24 bladder cancer cell line. 1989 Cancer Invest. pmid:2695227
Kojima S et al. Identification of myeloid origin in undifferentiated congenital leukemia by in vitro marrow culture study. 1989 Am J Pediatr Hematol Oncol pmid:2782565
Favinger J et al. Rhodospirillum centenum, sp. nov., a thermotolerant cyst-forming anoxygenic photosynthetic bacterium. 1989 Antonie Van Leeuwenhoek pmid:2757370
Marchant P et al. A selective inhibitor of N8-acetylspermidine deacetylation in mice and HeLa cells without effects on histone deacetylation. 1989 Arch. Biochem. Biophys. pmid:2757387
Herz F Effect of human serum on alkaline phosphatase induction in cultured human tumor cells. 1989 Experientia pmid:2759209
Beattie DT et al. Baclofen antagonism by 4-amino-3-(5-methoxybenzo[b]furan-2-yl) butanoic acid in the cat spinal cord. 1989 Neurosci. Lett. pmid:2761779
Chiao CS and Price JC Modification of gelatin beadlets for zero-order sustained release. 1989 Pharm. Res. pmid:2762229
Xu K et al. [Studies on cell surface fibronectin of transformed Syrian hamster lung cells induced by butyric acid]. 1989 Shi Yan Sheng Wu Xue Bao pmid:2763766
Ramanathan B and Smerdon MJ Enhanced DNA repair synthesis in hyperacetylated nucleosomes. 1989 J. Biol. Chem. pmid:2738057
Ramakrishna BS et al. Estimation of phenolic conjugation by colonic mucosa. 1989 J. Clin. Pathol. pmid:2738167
Higgins PJ and Ryan MP Cytoarchitecture of ras oncogene-expressing tumor cells: butyrate modulation of substrate adhesion, cytoskeletal actin content and subcellular microfilament distribution. 1989 Int. J. Biochem. pmid:2684700
Larno S et al. Sodium butyrate-induced structural and functional modifications in proteins of cultured rabbit articular chondrocytes. 1989 Cell. Mol. Biol. pmid:2731193
Eisner DA et al. A novel method for absolute calibration of intracellular pH indicators. 1989 Pflugers Arch. pmid:2740208
Tokunaga T et al. Utilization and excretion of a new sweetener, fructooligosaccharide (Neosugar), in rats. 1989 J. Nutr. pmid:2495342
Perry CA and Annunziato AT Influence of histone acetylation on the solubility, H1 content and DNase I sensitivity of newly assembled chromatin. 1989 Nucleic Acids Res. pmid:2740216
Cheng KJ et al. The characterization and ultrastructure of two new strains of Butyrivibrio. 1989 Can. J. Microbiol. pmid:2743214
Toribara NW et al. Heterogeneity in the induction and expression of carcinoembryonic antigen-related antigens in human colon cancer cell lines. 1989 Cancer Res. pmid:2720685
Radsak K et al. Induction by sodium butyrate of cytomegalovirus replication in human endothelial cells. 1989 Arch. Virol. pmid:2552958
James DE et al. Isoproterenol stimulates phosphorylation of the insulin-regulatable glucose transporter in rat adipocytes. 1989 Proc. Natl. Acad. Sci. U.S.A. pmid:2554313
Lotan R et al. Modulation of galactoside-binding lectins in tumor cells by differentiation-inducing agents. 1989 Cancer Lett. pmid:2555043
Yamazaki H [Induction of differentiation in testicular choriocarcinoma cells and its role in cancer therapy]. 1989 Nippon Hinyokika Gakkai Zasshi pmid:2556605
Nakamura CV and Pinto AS Biological effects of lithium chloride on the insect trypanosomatid Herpetomonas samuelpessoai. 1989 Parasitology pmid:2556681
KraevskiÄ­ VA et al. [Oscillatory changes in the transcription and supercoiling of minichromosomal DNA after the withdrawal of butyric acid from a mouse cell culture]. 1989 Dokl. Akad. Nauk SSSR pmid:2635665
Elliott WL et al. Testing for cell surface forms of class II major histocompatibility complex antigens and Ii by radioiodination, biotinylation, and membrane immunofluorescence. 1989 Am. J. Hematol. pmid:2642651
Neogrády S et al. Effects of butyrate and insulin and their interaction on the DNA synthesis of rumen epithelial cells in culture. 1989 Experientia pmid:2643531
Herman MM et al. Neuroblastic differentiation potential of the human retinoblastoma cell lines Y-79 and WERI-Rb1 maintained in an organ culture system. An immunohistochemical, electron microscopic, and biochemical study. 1989 Am. J. Pathol. pmid:2643884
Hoessly MC et al. Factors responsible for variable reported lineages of HL-60 cells induced to mature with butyric acid. 1989 Cancer Res. pmid:2567205
Poduslo SE Induction of ketone body enzymes in glial cells. 1989 Arch. Biochem. Biophys. pmid:2568818
Zielke HR et al. Effect of nerve growth factor on the synthesis of amino acids in PC12 cells. 1989 J. Neurosci. Res. pmid:2569539
Yang ZW et al. Expression of (+)-3-PPP binding sites in the PC12 pheochromocytoma cell line. 1989 Eur. J. Pharmacol. pmid:2569979
Shirasuna K et al. Different contents of glycosaminoglycans in a human neoplastic salivary duct cell line and its subclone with a myoepithelial phenotype. 1989 Virchows Arch., B, Cell Pathol. pmid:2570484
Subero O et al. Ca2+ requirement for metabolic effects of secretagogues in the amphibian gastric mucosa. 1989 Am. J. Physiol. pmid:2514602
Chander A Regulation of lung surfactant secretion by intracellular pH. 1989 Am. J. Physiol. pmid:2514603
Daniel P et al. Pharmacokinetic study of butyric acid administered in vivo as sodium and arginine butyrate salts. 1989 Clin. Chim. Acta pmid:2667816
Düsedau K et al. [The effect of intravenous administration of butyrate, isobutyrate and isovalerate to lambs aged 8-45 days on the blood plasma content of glucose, insulin, free fatty acids and total alpha-amino-N]. 1989 Arch Exp Veterinarmed pmid:2673127
Stoddart JH et al. Sodium butyrate suppresses the transforming activity of an activated N-ras oncogene in human colon carcinoma cells. 1989 Exp. Cell Res. pmid:2676572
Walker-Jones D et al. Stimulation of epithelial membrane antigen expression by transforming growth factor-beta in normal and oncogene-transformed human mammary epithelial cells. 1989 Cancer Res. pmid:2680064
Resnicoff M and Medrano EE Growth factors and hormones which affect survival, growth, and differentiation of the MCF-7 stem cells and their descendants. 1989 Exp. Cell Res. pmid:2645148
Gladhaug IP and Christoffersen T n-butyrate and dexamethasone synergistically modulate the surface expression of epidermal growth factor receptors in cultured rat hepatocytes. 1989 FEBS Lett. pmid:2646145
Hargreaves AJ et al. Sodium butyrate induces major morphological changes in C6 glioma cells that are correlated with increased synthesis of a spectrin-like protein. 1989 Brain Res. Dev. Brain Res. pmid:2653664