| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhou J et al. | Maternal sodium butyrate supplement elevates the lipolysis in adipose tissue and leads to lipid accumulation in offspring liver of weaning-age rats. | 2016 | Lipids Health Dis | pmid:27449927 |
| Astakhova L et al. | Short Chain Fatty Acids (SCFA) Reprogram Gene Expression in Human Malignant Epithelial and Lymphoid Cells. | 2016 | PLoS ONE | pmid:27441625 |
| Bai G et al. | Dietary Casein and Soy Protein Isolate Modulate the Effects of Raffinose and Fructooligosaccharides on the Composition and Fermentation of Gut Microbiota in Rats. | 2016 | J. Food Sci. | pmid:27434756 |
| Reijnders D et al. | Effects of Gut Microbiota Manipulation by Antibiotics on Host Metabolism in Obese Humans: A Randomized Double-Blind Placebo-Controlled Trial. | 2016 | Cell Metab. | pmid:27411009 |
| Venkataraman A et al. | Variable responses of human microbiomes to dietary supplementation with resistant starch. | 2016 | Microbiome | pmid:27357127 |
| Liang B and Fang J | Postnatal Isoflurane Exposure Induces Cognitive Impairment and Abnormal Histone Acetylation of Glutamatergic Systems in the Hippocampus of Adolescent Rats. | 2016 | J. Mol. Neurosci. | pmid:27307148 |
| Sjöblom M et al. | Catalytic upgrading of butyric acid towards fine chemicals and biofuels. | 2016 | FEMS Microbiol. Lett. | pmid:26994015 |
| Zhao Z et al. | Potential enhancement of direct interspecies electron transfer for syntrophic metabolism of propionate and butyrate with biochar in up-flow anaerobic sludge blanket reactors. | 2016 | Bioresour. Technol. | pmid:26967338 |
| Sun J et al. | Antidepressant-like effects of sodium butyrate and its possible mechanisms of action in mice exposed to chronic unpredictable mild stress. | 2016 | Neurosci. Lett. | pmid:26957230 |
| Su CL et al. | Epigenetic regulation of BDNF in the learned helplessness-induced animal model of depression. | 2016 | J Psychiatr Res | pmid:26921875 |
| Tanaka S et al. | Relationship of Enhanced Butyrate Production by Colonic Butyrate-Producing Bacteria to Immunomodulatory Effects in Normal Mice Fed an Insoluble Fraction of Brassica rapa L. | 2016 | Appl. Environ. Microbiol. | pmid:26921420 |
| Donovan JD et al. | Volatile Retention and Morphological Properties of Microencapsulated Tributyrin Varied by Wall Material and Drying Method. | 2016 | J. Food Sci. | pmid:26878682 |
| Wang ZT et al. | Histone deacetylase inhibitors suppress mutant p53 transcription via HDAC8/YY1 signals in triple negative breast cancer cells. | 2016 | Cell. Signal. | pmid:26876786 |
| Zounr RA et al. | Improved Gas Chromatographic Determination of Guanidino Compounds Using Isovaleroylacetone and Ethyl Chloroformate as Derivatizing Reagents. | 2016 | Anal Sci | pmid:26860556 |
| Mátis G et al. | Feed-drug interaction of orally applied butyrate and phenobarbital on hepatic cytochrome P450 activity in chickens. | 2016 | J Anim Physiol Anim Nutr (Berl) | pmid:26614344 |
| Luceri C et al. | Effect of butyrate enemas on gene expression profiles and endoscopic/histopathological scores of diverted colorectal mucosa: A randomized trial. | 2016 | Dig Liver Dis | pmid:26607831 |
| Kratsman N et al. | Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model. | 2016 | Neuropharmacology | pmid:26577018 |
| Heidor R et al. | The chemopreventive activity of butyrate-containing structured lipids in experimental rat hepatocarcinogenesis. | 2016 | Mol Nutr Food Res | pmid:26548572 |
| Cueno ME et al. | Periodontal disease level-butyric acid amounts locally administered in the rat gingival mucosa induce ER stress in the systemic blood. | 2016 | Microb. Pathog. | pmid:26541671 |
| Sergeev E et al. | Non-equivalence of Key Positively Charged Residues of the Free Fatty Acid 2 Receptor in the Recognition and Function of Agonist Versus Antagonist Ligands. | 2016 | J. Biol. Chem. | pmid:26518871 |
| Contreras-Leal E et al. | Histone deacetylase inhibitors promote the expression of ATP2A3 gene in breast cancer cell lines. | 2016 | Mol. Carcinog. | pmid:26331238 |
| Xing X et al. | Sodium butyrate protects against oxidative stress in HepG2 cells through modulating Nrf2 pathway and mitochondrial function. | 2016 | J. Physiol. Biochem. | pmid:28600747 |
| MartÃn Juárez J et al. | Saccharification of microalgae biomass obtained from wastewater treatment by enzymatic hydrolysis. Effect of alkaline-peroxide pretreatment. | 2016 | Bioresour. Technol. | pmid:27372005 |
| Khan S and Jena G | Sodium butyrate reduces insulin-resistance, fat accumulation and dyslipidemia in type-2 diabetic rat: A comparative study with metformin. | 2016 | Chem. Biol. Interact. | pmid:27270450 |
| Khairy H et al. | The NADH:flavin oxidoreductase Nox from Rhodococcus erythropolis MI2 is the key enzyme of 4,4'-dithiodibutyric acid degradation. | 2016 | Lett. Appl. Microbiol. | pmid:27564089 |
| Kong X et al. | Inhibiting excessive acidification using zero-valent iron in anaerobic digestion of food waste at high organic load rates. | 2016 | Bioresour. Technol. | pmid:26998799 |
| Bencsik R et al. | Improved transgene expression in doxycycline-inducible embryonic stem cells by repeated chemical selection or cell sorting. | 2016 | Stem Cell Res | pmid:27591479 |
| Han R et al. | Sodium Butyrate Upregulates miR-203 Expression to Exert Anti-Proliferation Effect on Colorectal Cancer Cells. | 2016 | Cell. Physiol. Biochem. | pmid:27771718 |
| Polak U et al. | Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming. | 2016 | Stem Cells Dev. | pmid:27615158 |
| Chen WS et al. | Effects of histone deacetylase inhibitor sodium butyrate on heroin seeking behavior in the nucleus accumbens in rats. | 2016 | Brain Res. | pmid:27742468 |
| Miao W et al. | Sodium Butyrate Promotes Reassembly of Tight Junctions in Caco-2 Monolayers Involving Inhibition of MLCK/MLC2 Pathway and Phosphorylation of PKCβ2. | 2016 | Int J Mol Sci | pmid:27735862 |
| Tayebi B et al. | Modulation of microRNAs expression in hematopoietic stem cells treated with sodium butyrate in inducing fetal hemoglobin expression. | 2017 | Artif Cells Nanomed Biotechnol | pmid:26837891 |
| Kamphayae S et al. | Effects of graded levels of liquid brewer's yeast on chemical composition and fermentation quality in cassava pulp and rice straw-based total mixed ration silage. | 2017 | Anim. Sci. J. | pmid:27611881 |
| Sasajima H et al. | Intranasal Administration of Rotenone to Mice Induces Dopaminergic Neurite Degeneration of Dopaminergic Neurons in the Substantia Nigra. | 2017 | Biol. Pharm. Bull. | pmid:28049942 |
| Kurano M et al. | Involvement of Band3 in the efflux of sphingosine 1-phosphate from erythrocytes. | 2017 | PLoS ONE | pmid:28494002 |
| Jaworska J et al. | The potential neuroprotective role of a histone deacetylase inhibitor, sodium butyrate, after neonatal hypoxia-ischemia. | 2017 | J Neuroinflammation | pmid:28187734 |
| Qiu Y et al. | Effect of sodium butyrate on cell proliferation and cell cycle in porcine intestinal epithelial (IPEC-J2) cells. | 2017 | In Vitro Cell. Dev. Biol. Anim. | pmid:28127702 |
| Tylichová Z et al. | Activation of autophagy and PPARγ protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation. | 2017 | J. Nutr. Biochem. | pmid:27840291 |
| Li P et al. | Effect of grape pomace on fermentation quality and aerobic stability of sweet sorghum silage. | 2017 | Anim. Sci. J. | pmid:28485116 |
| Donovan JD et al. | In Vitro Digestion and Fermentation of Microencapsulated Tributyrin for the Delivery of Butyrate. | 2017 | J. Food Sci. | pmid:28485486 |
| Zhou Z et al. | Changes of cecal microflora in chickens following Eimeria tenella challenge and regulating effect of coated sodium butyrate. | 2017 | Exp. Parasitol. | pmid:28455119 |
| Suo Y et al. | Enhanced butyric acid tolerance and production by Class I heat shock protein-overproducing Clostridium tyrobutyricum ATCC 25755. | 2017 | J. Ind. Microbiol. Biotechnol. | pmid:28439766 |
| Arriaga JM et al. | Metallothionein 1G promotes the differentiation of HT-29 human colorectal cancer cells. | 2017 | Oncol. Rep. | pmid:28393194 |
| Fu H et al. | Metabolic engineering of Clostridium tyrobutyricum for enhanced butyric acid production from glucose and xylose. | 2017 | Metab. Eng. | pmid:28040464 |
| Jin X et al. | TXNIP mediates the differential responses of A549 cells to sodium butyrate and sodium 4-phenylbutyrate treatment. | 2017 | Cancer Med | pmid:28033672 |
| Dai H et al. | Sodium Butyrate Ameliorates High-Concentrate Diet-Induced Inflammation in the Rumen Epithelium of Dairy Goats. | 2017 | J. Agric. Food Chem. | pmid:28032994 |
| Bosmans JW et al. | Comparison of three different application routes of butyrate to improve colonic anastomotic strength in rats. | 2017 | Int J Colorectal Dis | pmid:27942836 |
| Johnstone M et al. | Characterization of the Pro-Inflammatory Cytokine IL-1β on Butyrate Oxidation in Colorectal Cancer Cells. | 2017 | J. Cell. Biochem. | pmid:27922186 |
| Chriett S et al. | The histone deacetylase inhibitor sodium butyrate improves insulin signalling in palmitate-induced insulin resistance in L6 rat muscle cells through epigenetically-mediated up-regulation of Irs1. | 2017 | Mol. Cell. Endocrinol. | pmid:27619406 |
| Kumar G et al. | Microbial responses to various process disturbances in a continuous hydrogen reactor fed with galactose. | 2017 | J. Biosci. Bioeng. | pmid:27614820 |