butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Acidosis D000138 13 associated lipids
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Alzheimer Disease D000544 76 associated lipids
Anaplasia D000708 1 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Angina Pectoris D000787 27 associated lipids
Aphakia, Postcataract D001036 1 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Astigmatism D001251 1 associated lipids
Ataxia Telangiectasia D001260 6 associated lipids
Sarcoma, Avian D001357 2 associated lipids
Body Weight D001835 333 associated lipids
Brain Diseases D001927 27 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Burns D002056 34 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Cattle Diseases D002418 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Xu J et al. Effects of Early Intervention with Sodium Butyrate on Gut Microbiota and the Expression of Inflammatory Cytokines in Neonatal Piglets. 2016 PLoS ONE pmid:27611998
Kotantaki P and Mosialos G The expression of tumor suppressor gene Cyld is upregulated by histone deacetylace inhibitors in human hepatocellular carcinoma cell lines. 2016 Cell Biochem. Funct. pmid:27570065
Ávila M et al. Application of high pressure processing for controlling Clostridium tyrobutyricum and late blowing defect on semi-hard cheese. 2016 Food Microbiol. pmid:27554159
Rephaeli A et al. Bi-functional prodrugs of 5-aminolevulinic acid and butyric acid increase erythropoiesis in anemic mice in an erythropoietin-independent manner. 2016 Eur J Pharm Sci pmid:27283485
Moreno FS et al. Nutritional Epigenetics and the Prevention of Hepatocellular Carcinoma with Bioactive Food Constituents. 2016 Nutr Cancer pmid:27266713
Aguilar EC et al. Oral butyrate reduces oxidative stress in atherosclerotic lesion sites by a mechanism involving NADPH oxidase down-regulation in endothelial cells. 2016 J. Nutr. Biochem. pmid:27261536
Zeng J et al. Autophagy regulates biliary differentiation of hepatic progenitor cells through Notch1 signaling pathway. 2016 Cell Cycle pmid:27259983
Zhu P et al. [Effect and mechanism of inhibition of lipopolysaccharide-induced pulmonary fibrosis by butyric acid]. 2016 Zhonghua Wei Zhong Bing Ji Jiu Yi Xue pmid:26805528
Sayed M et al. Selective oxidation of trimethylolpropane to 2,2-bis(hydroxymethyl)butyric acid using growing cells of Corynebacterium sp. ATCC 21245. 2016 J. Biotechnol. pmid:26804932
Zhang J et al. Sodium Butyrate Induces Endoplasmic Reticulum Stress and Autophagy in Colorectal Cells: Implications for Apoptosis. 2016 PLoS ONE pmid:26784903
Silva FT et al. Replacement of sugars to hydrogen production by Rhodobacter capsulatus using dark fermentation effluent as substrate. 2016 Bioresour. Technol. pmid:26476167
Cueno ME and Ochiai K Re-discovering periodontal butyric acid: New insights on an old metabolite. 2016 Microb. Pathog. pmid:26466516
Rumpagaporn P et al. Elevated propionate and butyrate in fecal ferments of hydrolysates generated by oxalic acid treatment of corn bran arabinoxylan. 2016 Food Funct pmid:27841429
Youn YS et al. Molecular tuning of amino acids to form two-dimensional molecular networks driven by conformational preorganization. 2016 Chem. Commun. (Camb.) pmid:27858018
Liu Y et al. Dietary resistant starch type 4-derived butyrate attenuates nuclear factor-kappa-B1 through modulation of histone H3 trimethylation at lysine 27. 2016 Food Funct pmid:27713965
Khan S and Jena G Sodium butyrate reduces insulin-resistance, fat accumulation and dyslipidemia in type-2 diabetic rat: A comparative study with metformin. 2016 Chem. Biol. Interact. pmid:27270450
Zhang Z et al. O-Linked N-Acetylglucosamine (O-GlcNAc) Transferase and O-GlcNAcase Interact with Mi2β Protein at the Aγ-Globin Promoter. 2016 J. Biol. Chem. pmid:27231347
Grimaldi R et al. Fermentation properties and potential prebiotic activity of Bimuno® galacto-oligosaccharide (65 % galacto-oligosaccharide content) on in vitro gut microbiota parameters. 2016 Br. J. Nutr. pmid:27267934
Kulcsár A et al. Effects of butyrate on the insulin homeostasis of chickens kept on maize- or wheat-based diets. 2016 Acta Vet. Hung. pmid:27993103
Yan H and Ajuwon KM Mechanism of Butyrate Stimulation of Triglyceride Storage and Adipokine Expression during Adipogenic Differentiation of Porcine Stromovascular Cells. 2015 PLoS ONE pmid:26713737
Cui Y et al. Interference of the Histone Deacetylase Inhibits Pollen Germination and Pollen Tube Growth in Picea wilsonii Mast. 2015 PLoS ONE pmid:26710276
Saito K et al. Modulation of Cytokine Secretion Allows CD4 T Cells Secreting IL-10 and IL-17 to Simultaneously Participate in Maintaining Tolerance and Immunity. 2015 PLoS ONE pmid:26709703
Turon V et al. Growth of Chlorella sorokiniana on a mixture of volatile fatty acids: The effects of light and temperature. 2015 Bioresour. Technol. pmid:26461792
Muñoz-Rugeles L and Alvarez-Idaboy JR A proton-electron sequential transfer mechanism: theoretical evidence about its biological relevance. 2015 Phys Chem Chem Phys pmid:26456543
Sari O et al. Synthesis of dihydropyrimidine α,γ-diketobutanoic acid derivatives targeting HIV integrase. 2015 Eur J Med Chem pmid:26451771
Jin CJ et al. Supplementation of sodium butyrate protects mice from the development of non-alcoholic steatohepatitis (NASH). 2015 Br. J. Nutr. pmid:26450277
Nasser Al-Shorgani NK et al. Improvement of the butanol production selectivity and butanol to acetone ratio (B:A) by addition of electron carriers in the batch culture of a new local isolate of Clostridium acetobutylicum YM1. 2015 Anaerobe pmid:26439644
Zhong Y et al. Barley malt increases hindgut and portal butyric acid, modulates gene expression of gut tight junction proteins and Toll-like receptors in rats fed high-fat diets, but high advanced glycation end-products partially attenuate the effects. 2015 Food Funct pmid:26227569
Sandoval PY et al. Checkpoint Activation of an Unconventional DNA Replication Program in Tetrahymena. 2015 PLoS Genet. pmid:26218270
Valvassori SS et al. Sodium Butyrate, a Histone Deacetylase Inhibitor, Reverses Behavioral and Mitochondrial Alterations in Animal Models of Depression Induced by Early- or Late-life Stress. 2015 Curr Neurovasc Res pmid:26216027
Qaisrani SN et al. Diet structure, butyric acid, and fermentable carbohydrates influence growth performance, gut morphology, and cecal fermentation characteristics in broilers. 2015 Poult. Sci. pmid:26175052
Xu H et al. Sodium butyrate stimulates NHE8 expression via its role on activating NHE8 basal promoter activity. 2015 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:26159698
Guglielmetti S and Riso P Reply to Conlon et al. 2015 J. Nutr. pmid:26125075
Fukushima A et al. Ketogenic diet does not impair spatial ability controlled by the hippocampus in male rats. 2015 Brain Res. pmid:26111645
Steliou K et al. Bioprotective carnitinoids: lipoic acid, butyrate, and mitochondria-targeting to treat radiation injury: mitochondrial drugs come of age. 2015 Drug Dev. Res. pmid:26109467
Malago JJ and Sangu CL Intraperitoneal administration of butyrate prevents the severity of acetic acid colitis in rats. 2015 J Zhejiang Univ Sci B pmid:25743124
Shimoyama T et al. Study of the mechanisms of a Japanese traditional fermented medicine in the improvement of constipation. 2015 J. Gastroenterol. Hepatol. pmid:25827805
Huang YW et al. Brain isoform glycogen phosphorylase as a novel hepatic progenitor cell marker. 2015 PLoS ONE pmid:25826279
Chen L et al. Free and bound volatile chemicals in mulberry (Morus atropurpurea Roxb.). 2015 J. Food Sci. pmid:25817411
Cueno ME et al. High butyric acid amounts induce oxidative stress, alter calcium homeostasis, and cause neurite retraction in nerve growth factor-treated PC12 cells. 2015 Cell Stress Chaperones pmid:25808460
Kanika G et al. Sodium Butyrate Ameliorates L-Arginine-Induced Pancreatitis and Associated Fibrosis in Wistar Rat: Role of Inflammation and Nitrosative Stress. 2015 J. Biochem. Mol. Toxicol. pmid:25774002
Cao QF et al. TRPM2 mediates histone deacetylase inhibition-induced apoptosis in bladder cancer cells. 2015 Cancer Biother. Radiopharm. pmid:25760728
Mackmull MT et al. Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs). 2015 Mol. Cell Proteomics pmid:25755299
Varela RB et al. Sodium butyrate and mood stabilizers block ouabain-induced hyperlocomotion and increase BDNF, NGF and GDNF levels in brain of Wistar rats. 2015 J Psychiatr Res pmid:25467060
Turon V et al. Use of fermentative metabolites for heterotrophic microalgae growth: Yields and kinetics. 2015 Bioresour. Technol. pmid:25459841
Zgorzynska E et al. Docosahexaenoic acid attenuates oxidative stress and protects human gingival fibroblasts against cytotoxicity induced by hydrogen peroxide and butyric acid. 2015 Arch. Oral Biol. pmid:25455128
Lee C et al. Effect of 2-hydroxy-4-methylthio-butanoic acid on ruminal fermentation, bacterial distribution, digestibility, and performance of lactating dairy cows. 2015 J. Dairy Sci. pmid:25434334
Lopes-Borges J et al. Histone deacetylase inhibitors reverse manic-like behaviors and protect the rat brain from energetic metabolic alterations induced by ouabain. 2015 Pharmacol. Biochem. Behav. pmid:25433326
Simon-O'Brien E et al. The histone deacetylase inhibitor sodium butyrate decreases excessive ethanol intake in dependent animals. 2015 Addict Biol pmid:25041570
Katsou E et al. Coupling the treatment of low strength anaerobic effluent with fermented biowaste for nutrient removal via nitrite. 2015 J. Environ. Manage. pmid:25463576