butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kim JS et al. | High-level scu-PA production by butyrate-treated serum-free culture of recombinant CHO cell line. | Biotechnol. Prog. | pmid:15575713 | |
Roy MJ et al. | In vitro studies on the inhibition of colon cancer by butyrate and carnitine. | Nutrition | pmid:19619983 | |
Vester BM et al. | Influence of feeding raw or extruded feline diets on nutrient digestibility and nitrogen metabolism of African wildcats (Felis lybica). | Zoo Biol. | pmid:20095004 | |
Jolly RA et al. | Microvesicular steatosis induced by a short chain fatty acid: effects on mitochondrial function and correlation with gene expression. | Toxicol Pathol | pmid:15503661 | |
Wang Y et al. | Sodium butyrate-induced apoptosis and ultrastructural changes in MCF-7 breast cancer cells. | Ultrastruct Pathol | pmid:27158913 | |
Ibrahim MA | Assessment of insulin stability inside diblock copolymer PEG-PLA microspheres. | Sci Pharm | pmid:21179361 | |
Kim J et al. | Sodium butyrate regulates androgen receptor expression and cell cycle arrest in human prostate cancer cells. | Anticancer Res. | pmid:17970072 | |
Lee JS and Lee GM | Effect of sodium butyrate on autophagy and apoptosis in Chinese hamster ovary cells. | Biotechnol. Prog. | pmid:22492702 | |
Becker N et al. | Human intestinal microbiota: characterization of a simplified and stable gnotobiotic rat model. | Gut Microbes | pmid:21637015 | |
Soto-Cruz O et al. | Modeling of growth, lactate consumption, and volatile fatty acid production by Megasphaera elsdenii cultivated in minimal and complex media. | Biotechnol. Prog. | pmid:11934285 | |
Kodama N et al. | Induction of myeloperoxidase and nitrotyrosine formation in a human eosinophilic leukemia cell line, EoL-1. | Cell Biochem. Funct. | pmid:15027099 | |
Fontanellas A et al. | Hemoglobin content is increased in the human erythroleukemia K562 cell line by a 56.2-kD peptide from uremic plasma. | Am. J. Nephrol. | pmid:15024177 | |
pmid:16166714 | ||||
Vester BM et al. | Evaluation of nutrient digestibility and fecal characteristics of exotic felids fed horse- or beef-based diets: use of the domestic cat as a model for exotic felids. | Zoo Biol. | pmid:19830746 | |
Lea MA et al. | Induction of differentiation of colon cancer cells by combined inhibition of kinases and histone deacetylase. | Anticancer Res. | pmid:17465197 | |
Kien CL et al. | Lactulose feeding lowers cecal densities of clostridia in piglets. | JPEN J Parenter Enteral Nutr | pmid:17463144 | |
Sung YH et al. | Influence of down-regulation of caspase-3 by siRNAs on sodium-butyrate-induced apoptotic cell death of Chinese hamster ovary cells producing thrombopoietin. | Metab. Eng. | pmid:16169764 | |
Orchel A et al. | Influence of sodium butyrate on antioxidative enzymes activity in Caco-2 cell lines. | Acta Pol Pharm | pmid:17357609 | |
Noble R et al. | Olfactory response to mushroom composting emissions as a function of chemical concentration. | J. Environ. Qual. | pmid:11401265 | |
Nishinaga M et al. | Establishment of a microplate-formatted cell-based immunoassay for rapid analysis of nucleotide excision repair ability in human primary cells. | Photochem. Photobiol. | pmid:22220555 | |
Hossain Z et al. | Growth inhibition and induction of differentiation and apoptosis mediated by sodium butyrate in Caco-2 cells with algal glycolipids. | In Vitro Cell. Dev. Biol. Anim. | pmid:16153148 | |
Drozdowski LA et al. | Short-chain fatty acids and total parenteral nutrition affect intestinal gene expression. | JPEN J Parenter Enteral Nutr | pmid:12005453 | |
Lokshina LY et al. | Modeling of anaerobic degradation of solid slaughterhouse waste: inhibition effects of long-chain fatty acids or ammonia. | Appl. Biochem. Biotechnol. | pmid:12794281 | |
Loughrin JH et al. | Evaluation of second-generation multistage wastewater treatment system for the removal of malodors from liquid swine waste. | J. Environ. Qual. | pmid:19549951 | |
Oh HK et al. | Effect of N-Acetylcystein on butyrate-treated Chinese hamster ovary cells to improve the production of recombinant human interferon-beta-1a. | Biotechnol. Prog. | pmid:16080696 | |
pmid: | ||||
Gassull MA et al. | Macronutrients and bioactive molecules: is there a specific role in the management of inflammatory bowel disease? | JPEN J Parenter Enteral Nutr | pmid:15980281 | |
Wang B et al. | Butyrate inhibits functional differentiation of human monocyte-derived dendritic cells. | Cell. Immunol. | pmid:18522857 | |
Fang HH et al. | Effects of Mo(VI) on phototrophic hydrogen production by Rhodobacter sphaeroides. | Environ Technol | pmid:21970170 | |
Wang Q et al. | Characterization of monocarboxylate transport in human kidney HK-2 cells. | Mol. Pharm. | pmid:17140255 | |
Cenkvári E et al. | Investigations on the effects of Ca-soap of linseed oil on rumen fermentation in sheep and on milk composition of goats. | J Anim Physiol Anim Nutr (Berl) | pmid:15787990 | |
Fathallah H et al. | Differences in response to fetal hemoglobin induction therapy in beta-thalassemia and sickle cell disease. | Blood Cells Mol. Dis. | pmid:19346141 | |
Grebenová D et al. | The proteomic study of sodium butyrate antiproliferative/cytodifferentiation effects on K562 cells. | Blood Cells Mol. Dis. | pmid:16978890 | |
Bartholome AL et al. | Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal piglets. | JPEN J Parenter Enteral Nutr | pmid:15291402 | |
Bijaya G et al. | Synthesis and evaluation of esmolol prodrugs for transdermal delivery. | Drug Deliv | pmid:20553111 | |
Barker HA et al. | The Synthesis of Butyric and Caproic Acids from Ethanol and Acetic Acid by Clostridium Kluyveri. | 1945 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16588706 |
TOBIE WC and AYRES GB | alpha-Hydroxyisobutyric acid buffers (pH 2.3-5.0) not altered in pH by mold growth. | 1945 | J. Bacteriol. | pmid:21005569 |
VISSCHER FE | Renal clearance of beta-hydroxybutyric acid in a dog. | 1945 | Proc. Soc. Exp. Biol. Med. | pmid:21006321 |
AXELROD AE et al. | The differential effect of biotin sulfone and gamma-(3,4-ureylenecyclohexyl) butyric acid upon the microbiological activity of biotin and oxybiotin. | 1946 | J. Biol. Chem. | pmid:20985652 |
RABE RF | Butyric acid and duodenal ulcer. | 1946 | J Am Inst Homeopath | pmid:20988470 |
WILLIAMSON J and LOURIE EM | Interference with the trypanocidal action of gamma-(p-arsenosophenyl) butyric acid by p-aminobenzoic acid. | 1946 | Ann Trop Med Parasitol | pmid:20997909 |
TOBIE WC and AYRES GB | Action of alpha-hydroxyisobutyric acid on micro-organisms. | 1946 | Nature | pmid:21064937 |
HARTELIUS V and JOHANSEN G | The influence of alpha, gamma-dihydroxy-beta, beta-dimethyl-butyric acid on yeast growth. | 1946 | Cr Trav Lab Carlsberg Ser Physiol | pmid:21028375 |
LIFSON N and LORBER V | Pathways of conversion of butyrate carbon to rat liver glycogen. | 1947 | Fed. Proc. | pmid:20342751 |
MASON LS and ROBINSON AL | The heats of dilution of aqueous solutions of four amino butyric acids at 25 degrees. | 1947 | J. Am. Chem. Soc. | pmid:20292475 |
WALTER M | [Not Available]. | 1947 | Z Vitam Forsch | pmid:20296102 |
Bhat JV and Barker HA | Clostridium lacto-acetophilum Nov. Spec. and the Role of Acetic Acid in the Butyric Acid Fermentation of Lactate. | 1947 | J. Bacteriol. | pmid:16561372 |
ROBERTS S and SZEGO CM | The influence of fasting on the peripheral utilization of sodium beta-hydroxybutyrate in the rat. | 1947 | Fed. Proc. | pmid:20244242 |
LACKEY RW et al. | Effect on cardiac glycogen of intravenously administered sodium acetoacetate, sodium beta-hydroxybutyrate and sodium butyrate. | 1947 | Proc. Soc. Exp. Biol. Med. | pmid:18921782 |
CLARK FM and DEHR A | A study of butyric acid-producing anaerobes isolated from spoiled canned tomatoes. | 1947 Mar-Apr | Food Res | pmid:20294337 |