butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hamasaki Y et al. | Butyric acid enhances cyclooxygenase activity in rat basophilic leukemia 2H3 cells. | 1988 | Nippon Ketsueki Gakkai Zasshi | pmid:3144111 |
Kan YY et al. | Effects of polar organic compounds on gynecologic cancers. | 1988 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:3224317 |
Clouet PM and Bourre JM | Ketone body utilization for lipid synthesis in the murine sciatic nerve: alterations in the dysmyelinating trembler mutant. | 1988 | J. Neurochem. | pmid:3361304 |
Salam S | Inhibitor(S) of prostaglandin endoperoxide synthase and lipoxygenase activity in extracts of barley. | 1988 | Pak J Pharm Sci | pmid:16414615 |
Staecker JL et al. | Sodium butyrate preserves aspects of the differentiated phenotype of normal adult rat hepatocytes in culture. | 1988 | J. Cell. Physiol. | pmid:2899578 |
Almlöf I et al. | Induction of basophilic differentiation in the human basophilic cell line KU812. | 1988 | Scand. J. Immunol. | pmid:2973655 |
Zhu XZ and Chuang DM | Differential regulation by butyrate and dibutyryl cyclic AMP of delta-opioid, alpha 2-adrenergic, and muscarinic cholinergic receptors in NCB-20 cells. | 1988 | J. Neurochem. | pmid:2826684 |
Hutt-Taylor SR et al. | Sodium butyrate and a T lymphocyte cell line-derived differentiation factor induce basophilic differentiation of the human promyelocytic leukemia cell line HL-60. | 1988 | Blood | pmid:2446679 |
Rossi JF et al. | Phenotypic and functional analysis of 1,25-dihydroxyvitamin D3 receptor mediated modulation of the human myeloma cell line RPMI 8226. | 1988 | Cancer Res. | pmid:2830017 |
Germain L et al. | Promotion of growth and differentiation of rat ductular oval cells in primary culture. | 1988 | Cancer Res. | pmid:2446746 |
Takeyasu K et al. | Ouabain-sensitive (Na+ + K+)-ATPase activity expressed in mouse L cells by transfection with DNA encoding the alpha-subunit of an avian sodium pump. | 1988 | J. Biol. Chem. | pmid:2831227 |
Sorimachi K | Induction of alkaline phosphatase activity by synergistic action of dibutyryl cyclic adenosine monophosphate, prednisolone, butyrate and sodium chloride in cultured cells. | 1988 | Cell Biochem. Funct. | pmid:2832093 |
Tamura RN and Cox GS | Effect of pyrimidine deoxynucleosides and sodium butyrate on expression of the glycoprotein hormone alpha-subunit and placental alkaline phosphatase in HeLa cells. | 1988 | Biochim. Biophys. Acta | pmid:2449248 |
Halgunset J et al. | Butyrate effects on growth, morphology, and fibronectin production in PC-3 prostatic carcinoma cells. | 1988 | Prostate | pmid:2450342 |
Sack TL et al. | Cyclic-AMP-stimulated synthesis and release of carcinoembryonic antigen by pancreatic cancer cells. | 1988 | Int. J. Pancreatol. | pmid:2834472 |
Ladoux A et al. | An increase in intracellular pH is a general response of promonocytic cells to differentiating agents. | 1988 | FEBS Lett. | pmid:2455658 |
Pennypacker KR et al. | Calmodulin-binding proteins in human Y-79 retinoblastoma and HTB-14 glioma cell lines. | 1988 | J. Neurochem. | pmid:2834519 |
Kassis S et al. | Modulation of the beta-adrenergic receptor-coupled adenylate cyclase by chemical inducers of differentiation: effects on beta receptors and the inhibitory regulatory protein Gi. | 1988 | J. Recept. Res. | pmid:2455808 |
Murray SA and Taylor F | Dibutyryl cyclic AMP modulation of gap junctions in SW-13 human adrenal cortical tumor cells. | 1988 | Am. J. Anat. | pmid:2835894 |
Spiegel S | Insertion of ganglioside GM1 into rat glioma C6 cells renders them susceptible to growth inhibition by the B subunit of cholera toxin. | 1988 | Biochim. Biophys. Acta | pmid:2835987 |
Germain L et al. | Biliary epithelial and hepatocytic cell lineage relationships in embryonic rat liver as determined by the differential expression of cytokeratins, alpha-fetoprotein, albumin, and cell surface-exposed components. | 1988 | Cancer Res. | pmid:2457432 |
Sorimachi K et al. | Requirement of serum pretreatment for induction of alkaline phosphatase activity with prednisolone, butyrate, dibutyryl cyclic adenosine monophosphate and NaCl in human liver cells continuously cultured in serum-free medium. | 1988 | Cell Struct. Funct. | pmid:2836073 |
Lee KL et al. | The effects of sodium butyrate on the retinoic acid-induced changes in 1,25-dihydroxyvitamin D3 receptors in tumorigenic and nontumorigenic bone derived cell lines. | 1988 | Endocrinology | pmid:2836162 |
Gross JL et al. | Plasminogen activator and inhibitor activity in human glioma cells and modulation by sodium butyrate. | 1988 | Cancer Res. | pmid:3121170 |
Nishimura J et al. | Regulation of biosynthesis and phosphorylation of P210bcr/abl protein during differentiation induction of K 562 cells. | 1988 | Leuk. Res. | pmid:2464113 |
Baskova IP et al. | Thrombolytic agents of the preparation from the medicinal leeches. | 1988 | Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. | pmid:2459014 |
Boerner P and Saier MH | Effects of 5-azacytidine, sodium butyrate, and phorbol esters on amino acid transport system A in a kidney epithelial cell line, MDCK: evidence for multiple mechanisms of regulation. | 1988 | J. Cell. Physiol. | pmid:2459137 |
Burns LJ et al. | Butyrate induces selective transcriptional activation of a hypomethylated embryonic globin gene in adult erythroid cells. | 1988 | Blood | pmid:2460154 |
Perrine SP et al. | Butyrate infusions in the ovine fetus delay the biologic clock for globin gene switching. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2460870 |
Herlyn M et al. | Regulatory factors that determine growth and phenotype of normal human melanocytes. | 1988 | Exp. Cell Res. | pmid:2461309 |
Inhorn L et al. | Restoration of adenylate cyclase responsiveness in murine myeloid leukemia permits inhibition of proliferation by hormone. Butyrate augments catalytic activity of adenylate cyclase. | 1988 | Blood | pmid:3128344 |
Asher C and Garty H | Aldosterone increases the apical Na+ permeability of toad bladder by two different mechanisms. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3140240 |
Spotti D et al. | Intermediary metabolism and glycemic control in insulin-dependent diabetic uremic patients treated by continuous peritoneal dialysis. | 1988 | Nephron | pmid:3041295 |
Fischkoff SA | Graded increase in probability of eosinophilic differentiation of HL-60 promyelocytic leukemia cells induced by culture under alkaline conditions. | 1988 | Leuk. Res. | pmid:3184985 |
Takano M et al. | Sodium butyrate increases glucose transporter expression in LLC-PK1 cells. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3186708 |
Januszewicz E et al. | Butyric acid: inhibition of non-leukemic and chronic myeloid leukemia granulocyte macrophage clonal growth. | 1988 | Med Oncol Tumor Pharmacother | pmid:3193830 |
Rhoads DB et al. | Evidence for expression of the facilitated glucose transporter in rat hepatocytes. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3194405 |
Brass EP and Beyerinck RA | Effects of propionate and carnitine on the hepatic oxidation of short- and medium-chain-length fatty acids. | 1988 | Biochem. J. | pmid:3134008 |
Schönfeld P et al. | On the mechanism of the so-called uncoupling effect of medium- and short-chain fatty acids. | 1988 | Biochim. Biophys. Acta | pmid:3196710 |
Toscani A et al. | Molecular analysis of sodium butyrate-induced growth arrest. | 1988 | Oncogene Res. | pmid:3144695 |
Graham KA and Buick RN | Sodium butyrate induces differentiation in breast cancer cell lines expressing the estrogen receptor. | 1988 | J. Cell. Physiol. | pmid:3294239 |
Durix A and Jean-Blain C | [Influence of fasting and the dietary lipid content on ketogenesis in isolated rabbit hepatocytes]. | 1988 | Reprod Nutr Dev | pmid:3254599 |
Nakagawa T et al. | Transcriptional and posttranscriptional modulation of calcitonin gene expression by sodium n-butyrate in cultured human medullary thyroid carcinoma. | 1988 | Cancer Res. | pmid:3258183 |
Filippovich IV et al. | Effect of the inducers of cellular differentiation and of ionizing radiation on thymus lymphocytes: chromatin degradation and programmed cell death. | 1988 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:3258296 |
Gladhaug IP et al. | Effects of butyrate on epidermal growth factor receptor binding, morphology, and DNA synthesis in cultured rat hepatocytes. | 1988 | Cancer Res. | pmid:3263190 |
Yeger H et al. | Phenotypic and molecular characterization of inducible human neuroblastoma cell lines. | 1988 | Differentiation | pmid:3243386 |
Chatham J et al. | Inhibition of glucose phosphorylation by fatty acids in the perfused rat heart. | 1988 | FEBS Lett. | pmid:3169268 |
Kéri G et al. | Comparison of the tyrosine kinase activity with the proliferation rate in human colon solid tumors and tumor cell lines. | 1988 | Tumour Biol. | pmid:3206110 |
Albertini S et al. | The in vitro porcine brain tubulin assembly assay: effects of a genotoxic carcinogen (aflatoxin B1), eight tumor promoters and nine miscellaneous substances. | 1988 | Mutat. Res. | pmid:3173378 |
Nishiya I et al. | Relationship between changes of the steroid receptor and synchronization in human endometrial adenocarcinoma cells in vitro. | 1988 | Cytometry | pmid:3208623 |
Yusta B et al. | Mechanism of L-triiodothyronine (T3) uptake by glial C6 cells: regulation by butyrate. | 1988 | Mol. Cell. Endocrinol. | pmid:3208994 |
Gressner AM and Haarmann R | Effect of n-butyrate on the synthesis of sulfated glycosaminoglycans and hyaluronate by rat liver fat-storing cells (Ito cells). | 1988 | Biochem. Pharmacol. | pmid:3178890 |
Vernia P et al. | Organic anions and the diarrhea of inflammatory bowel disease. | 1988 | Dig. Dis. Sci. | pmid:3180970 |
Leith JT | Potentiation of X ray sensitivity by combinations of sodium butyrate and buthionine sulfoximine. | 1988 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:3182335 |
Chang CC et al. | Effects of sodium butyrate on the secretion of beta-2-microglobulin and calcitonin in a human ovarian cancer cell line OC-3-VGH. | 1988 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:3066455 |
Ortiz-Caro J et al. | Proliferation and differentiation are not directly related to H1(0) accumulation in cultured glial cells. | 1988 | Brain Res. | pmid:3219583 |
Campbell M and Chader GJ | Retinoblastoma cells in tissue culture. | 1988 | Ophthalmic Paediatr Genet | pmid:3068600 |
Ohwaki K | [High carboxylic acid level in the gingival crevicular fluid (GCF) of the patients with advanced periodontal disease]. | 1988 | Nihon Shishubyo Gakkai Kaishi | pmid:3078007 |
Herold KM and Rothberg PG | Evidence for a labile intermediate in the butyrate induced reduction of the level of c-myc RNA in SW837 rectal carcinoma cells. | 1988 | Oncogene | pmid:3078950 |
Maddox AM and Haddox MK | Characteristics of cyclic AMP enhancement of retinoic acid induction of increased transglutaminase activity in HL60 cells. | 1988 | Exp. Cell Biol. | pmid:2903078 |
Hellweg R et al. | Nerve growth factor synthesis in cultured rat iris: modulation by endogenous transmitter substances. | 1988 | Exp. Cell Res. | pmid:2844567 |
Hidal JT and Kaplan MM | Inhibition of thyroxine 5'-deiodination type II in cultured human placental cells by cortisol, insulin, 3', 5'-cyclic adenosine monophosphate, and butyrate. | 1988 | Metab. Clin. Exp. | pmid:2838733 |
Laeng H et al. | Participation of mitochondrial proliferation in morphological differentiation of murine mastocytoma cells. | 1988 | Exp. Cell Res. | pmid:2844569 |
Courtin F et al. | Induction of type II 5'-deiodinase activity by cyclic adenosine 3', 5'-monophosphate in cultured rat astroglial cells. | 1988 | Endocrinology | pmid:2841100 |
Ryan MP and Higgins PJ | Cytoarchitecture of Kirsten sarcoma virus-transformed rat kidney fibroblasts: butyrate-induced reorganization within the actin microfilament network. | 1988 | J. Cell. Physiol. | pmid:2844835 |
Langdon SP et al. | Effect of sodium butyrate and other differentiation inducers on poorly differentiated human ovarian adenocarcinoma cell lines. | 1988 | Cancer Res. | pmid:3167862 |
Rodgers RJ et al. | Secretion of progesterone and prostaglandins by cells of bovine corpora lutea from three stages of the luteal phase. | 1988 | J. Endocrinol. | pmid:2842428 |
Kaneko Y et al. | Fibroblast-like transformation and c-myc gene alteration of human hepatocytes induced by novobiocin and butyrate. | 1988 | Biochem. Biophys. Res. Commun. | pmid:2843181 |
Sutherland GR et al. | A BrdU-enhanceable fragile site or viral modification site at 11q23.1 in lymphoblastoid cultures. | 1988 | Cytogenet. Cell Genet. | pmid:2843323 |
Powers AC et al. | Sodium butyrate increases glucagon and insulin gene expression by recruiting immunocytochemically negative cells to produce hormone. | 1988 | Diabetes | pmid:2843409 |
Kisauzi DN and Leek BF | Liver blood flow and volatile fatty acid utilization in sheep before and after carbon tetrachloride treatment. | 1988 | J. Comp. Pathol. | pmid:3417915 |
Bidet M et al. | Role of monocarboxylic acid transport in intracellular pH regulation of isolated proximal cells. | 1988 | Biochim. Biophys. Acta | pmid:3342236 |
Davidson AM and Halestrap AP | Inorganic pyrophosphate is located primarily in the mitochondria of the hepatocyte and increases in parallel with the decrease in light-scattering induced by gluconeogenic hormones, butyrate and ionophore A23187. | 1988 | Biochem. J. | pmid:2845949 |
Yusta B et al. | Comparison of the effects of forskolin and dibutyryl cyclic AMP in neuroblastoma cells: evidence that some of the actions of dibutyryl cyclic AMP are mediated by butyrate. | 1988 | J. Neurochem. | pmid:2846786 |
Yokochi T et al. | Effect of activation of the Epstein-Barr virus genome on expression of B cell differentiation antigens of Burkitt's lymphoma lines. | 1988 | Microbiol. Immunol. | pmid:2850450 |
Morise T et al. | Biological activity of partially purified digitalis-like substance and Na-K-ATPase inhibitor in rats. | 1988 | Jpn. Circ. J. | pmid:2852264 |
Ortiz-Caro J et al. | Short chain fatty acids modulate nuclear receptor and extranuclear L-triiodothyronine levels in glial C6 cells by different mechanisms. | 1988 | Endocrinology | pmid:2836168 |
Li JS and Cheng YC | Interaction of Epstein-Barr virus DNA polymerase with aphidicolin, phosphonoformate and 5'-GMP. | 1988 | Virus Genes | pmid:2852412 |
Prasad S and Thakur MK | Age-dependent effects of sodium butyrate and hydrocortisone on acetylation of high mobility group proteins of rat liver. | 1988 | Biochem. Int. | pmid:3365268 |
Suzuki J et al. | Photochemical mutagen formation from aerobically treated night-soil effluent and the contributive substances. | 1988 | Environ. Pollut. | pmid:15092599 |
Niles RM et al. | The effect of sodium butyrate and retinoic acid on growth and CEA production in a series of human colorectal tumor cell lines representing different states of differentiation. | 1988 | Cancer Invest. | pmid:3365571 |
Leith JT | Modification of the hypoxic fraction of a xenografted human colon tumor by differentiation-inducing agents. | 1988 | J. Natl. Cancer Inst. | pmid:3367384 |
Cattini PA et al. | Effect of butyrate on thyroid hormone-mediated gene expression in rat pituitary tumour cells. | 1988 | Mol. Cell. Endocrinol. | pmid:3371552 |
Leith JT et al. | Changes in X-ray sensitivity and glutathione content of human colon tumor cells after exposure to the differentiation-inducing agent sodium butyrate. | 1988 | Radiat. Res. | pmid:3375444 |
Joshi SS et al. | Effects of differentiation inducing chemicals on in vivo malignancy and NK susceptibility of metastatic lymphoma cells. | 1988 | Cancer Detect. Prev. | pmid:3390859 |
Kamech N and Seif R | Evidence for new cellular proteins which may negatively control DNA replication or cell growth in rat 3T3 fibroblasts. | 1988 | Exp. Cell Res. | pmid:3391246 |
Reading CL et al. | Analysis of cell surface glycoprotein changes related to hematopoietic differentiation. | 1988 | J. Cell. Biochem. | pmid:3392108 |
Staecker JL and Pitot HC | The effect of sodium butyrate on tyrosine aminotransferase induction in primary cultures of normal adult rat hepatocytes. | 1988 | Arch. Biochem. Biophys. | pmid:2895606 |
Tatsuka M et al. | An improved method of electroporation for introducing biologically active foreign genes into cultured mammalian cells. | 1988 | Exp. Cell Res. | pmid:3409976 |
Drucker DJ et al. | Proglucagon gene expression and posttranslational processing in a hamster islet cell line. | 1988 | Endocrinology | pmid:3416818 |
Chan WC et al. | Large granular lymphocyte proliferation: an analysis of T-cell receptor gene arrangement and expression and the effect of in vitro culture with inducing agents. | 1988 | Blood | pmid:2961380 |
Szabad J et al. | The effects of two mutations connected with chromatin functions on female germ-line cells of Drosophila. | 1988 | Mol. Gen. Genet. | pmid:3422705 |
Giancotti V et al. | Butyrate effect on nuclear proteins of two Chinese hamster cell lines. | 1988 | Exp. Cell Res. | pmid:3335229 |
Spector R | Fatty acid transport through the blood-brain barrier. | 1988 | J. Neurochem. | pmid:3335863 |
Effects of short-chain fatty acids on a human colon carcinoma cell line. | 1988 | Nutr. Rev. | pmid:3340339 | |
Hallows KR et al. | Effects of the differentiating agents sodium butyrate and N-methylformamide on the oxygen enhancement ratio of human colon tumor cells. | 1988 | Radiat. Res. | pmid:3340722 |
Berry RD and Paraskeva C | Expression of carcinoembryonic antigen by adenoma and carcinoma derived epithelial cell lines: possible marker of tumour progression and modulation of expression by sodium butyrate. | 1988 | Carcinogenesis | pmid:3345582 |
Reynier MO et al. | Influence of lipid-rich diets on intestinal cholesterol uptake. | 1988 | Ann. Nutr. Metab. | pmid:3355108 |
Zhang DE and Nelson DA | Histone acetylation in chicken erythrocytes. Rates of deacetylation in immature and mature red blood cells. | 1988 | Biochem. J. | pmid:3355515 |
Virtanen I et al. | Expression of intermediate filaments and synaptophysin show neuronal properties and lack of glial characteristics in Y79 retinoblastoma cells. | 1988 | Lab. Invest. | pmid:3141718 |