butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Palmer TN et al. | Can isolated spans of the tricarboxylic acid cycle operate independently? L-proline, oleate and butyrate metabolism in rat hepatocytes. | 1983 | Biochem. Int. | pmid:6435625 |
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Matsui I et al. | Induction of spermidine N1-acetyltransferase by sodium n-butyrate and phytohemagglutinin in bovine lymphocytes. | 1983 | J. Biochem. | pmid:6305929 |
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Goz B et al. | Effect of ethanol on alkaline phosphatase activity in HeLa cells. | 1983 | Alcohol. Clin. Exp. Res. | pmid:6346920 |
Hoberg KA et al. | Inhibitory effect of cerulenin and sodium butyrate on germination of Candida albicans. | 1983 | Antimicrob. Agents Chemother. | pmid:6357077 |
Melzig M and Teuscher E | [Effect of blood factors on the myosin content of cultured vascular smooth muscle cells]. | 1983 | Acta Histochem. | pmid:6421075 |
Butt TR and Sreevalsan T | Interferon and sodium butyrate inhibit the stimulation of poly(ADP-ribose) synthetase in mouse cells stimulated to divide. | 1983 | Exp. Cell Res. | pmid:6313413 |
Multhaup I et al. | Conservation of the acetylation pattern of histones and the transcriptional activity in Ehrlich ascites tumor cells by sodium butyrate. | 1983 | Arch. Biochem. Biophys. | pmid:6189452 |
Panet R et al. | Rb+ influxes differentiate between growth arrest of cells by different agents. | 1983 | J. Membr. Biol. | pmid:6313930 |
Tralka TS et al. | Butyrate increases type-A and type-R virus-like particles in BKV-transformed hamster spleen cells. | 1983 | Proc. Soc. Exp. Biol. Med. | pmid:6314342 |
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Gorman CM et al. | Expression of recombinant plasmids in mammalian cells is enhanced by sodium butyrate. | 1983 | Nucleic Acids Res. | pmid:6316266 |
Barin F et al. | Further studies on production and characterization of HBsAg derived from a human hepatoma cell line (PLC/PRF/5). | 1983 | Dev. Biol. Stand. | pmid:6317496 |
Hiramatsu M et al. | Effect of dibutyryl cyclic AMP on collagen synthesis in a clonal osteoblast-like cell line derived from newborn mouse calvaria. | 1983 | J. Biochem. | pmid:6317664 |
McMorris FA | Cyclic AMP induction of the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphohydrolase in rat oligodendrocytes. | 1983 | J. Neurochem. | pmid:6308162 |
Dayal V et al. | Cyclic AMP induces synthesis of prostaglandin E1 in platelets. | 1983 | Biochim. Biophys. Acta | pmid:6309248 |
Smerdon MJ | Rearrangements of chromatin structure in newly repaired regions of deoxyribonucleic acid in human cells treated with sodium butyrate or hydroxyurea. | 1983 | Biochemistry | pmid:6615781 |
Halleck MS and Schlegel RA | C-banding of Peromyscus constitutive heterochromatin persists following histone hyperacetylation. | 1983 | Exp. Cell Res. | pmid:6617770 |
Okuno E et al. | Effect of chronic administration of riboflavin 2',3',4',5'-tetrabutyrate on the hepatic enzymes of fatty acid oxidation in the rat. | 1983 | J. Nutr. Sci. Vitaminol. | pmid:6676446 |
Derr RF et al. | Suppression of an ethanol withdrawal syndrome in rats by butyrate, lactate and beta-hydroxybutyrate. | 1983 | Life Sci. | pmid:6682922 |
Okabe-Kado J et al. | Effects of inducers of erythroid differentiation of human leukemia K562 cells on vincristine-resistant K562/VCR cells. | 1983 | Leuk. Res. | pmid:6684716 |
Müllner E et al. | Increased levels of dihydrofolate reductase mRNA can be measured in normal, growth-stimulated mouse fibroblasts. | 1983 | Biochim. Biophys. Acta | pmid:6688360 |
Edwards MK et al. | Induced muscle differentiation in an embryonal carcinoma cell line. | 1983 | Mol. Cell. Biol. | pmid:6656767 |
Heard JM et al. | Autocrine function of murine F-MuLV induced myeloblastic cell lines. | 1983 | Int. J. Cancer | pmid:6600723 |
Targowski SP and Klucinski W | Reduction in mitogenic response of bovine lymphocytes by ketone bodies. | 1983 | Am. J. Vet. Res. | pmid:6603180 |
Nozawa S et al. | Sodium butyrate produces concordant expression of "early placental" alkaline phosphatase, pregnancy-specific beta 1-glycoprotein and human chronic gonadotropin beta-subunit in a newly established uterine cervical cancer cell line (SKG-IIIa). | 1983 | Int. J. Cancer | pmid:6604031 |
Ravid A et al. | Inhibition of phorbol ester-mediated interleukin-2 production by cellular differentiating agents. | 1983 | Cancer Res. | pmid:6604573 |
Novogrodsky A et al. | Effect of polar organic compounds on leukemic cells. Butyrate-induced partial remission of acute myelogenous leukemia in a child. | 1983 | Cancer | pmid:6571794 |
Zucker RM et al. | The effect of glutathione on HL-60 treated with dimethylsulfoxide, butyric acid or 12-O-tetradecanoylphorbol-13-acetate. | 1983 | FEBS Lett. | pmid:6573264 |
Zucker RM et al. | Differentiation of HL-60 cells: cell volume and cell cycle changes. | 1983 | Cytometry | pmid:6574016 |
Reboulleau CP et al. | Maintenance of DNA integrity during murine erythroleukemia cell differentiation induced by ethionine and other hypomethylation agents. | 1983 | Biochim. Biophys. Acta | pmid:6574790 |
Villeval JL et al. | Erythroid properties of K562 cells. Effect of hemin, butyrate and TPA induction. | 1983 | Exp. Cell Res. | pmid:6575918 |
Levenson R et al. | Ionic regulation of MEL cell commitment. | 1983 | J. Cell. Biochem. | pmid:6575972 |
Eliasson L et al. | Epstein-Barr virus and tumor promoters. | 1983 | Int. Symp. Princess Takamatsu Cancer Res. Fund | pmid:6097578 |
Chou JY | Production of pregnancy-specific beta 1-glycoprotein by human placental cells and human fibroblasts. | 1983 | Oncodev. Biol. Med. | pmid:6190140 |
Daniel P et al. | [Bladder papilloma. Treatment with interferon, sodium butyrate and isoprinosine]. | 1983 | Presse Med | pmid:6190163 |
Chany C et al. | Effect of coordinated therapeutic assays using C. parvum, interferon and arginine butyrate on spontaneous disease and survival of AKR mice. | 1983 | Int. J. Cancer | pmid:6193071 |
Braas KM et al. | Induction of differentiation increases Met5-enkephalin and Leu5-enkephalin content in NG108-15 hybrid cells: an immunocytochemical and biochemical analysis. | 1983 | J. Neurosci. | pmid:6193253 |
Segal NB and Guttman FM | Rabbit kidney function in vitro: the effect of colloids, energy substrate, a vasodilator, perfusion pressure, and bovine serum albumin. | 1983 | Cryobiology | pmid:6194936 |
Zucker RM et al. | 5-Azacytidine increases the synthesis of embryonic hemoglobin (E2) in murine erythroleukemic cells. | 1983 | FEBS Lett. | pmid:6195020 |
Wintersberger E et al. | Butyrate inhibits mouse fibroblasts at a control point in the G1 phase. | 1983 | J. Cell. Biochem. | pmid:6195168 |
Bhat NR et al. | Cell proliferation in growing cultures of dissociated embryonic mouse brain: macromolecule and ornithine decarboxylase synthesis and regulation by hormones and drugs. | 1983 | J. Neurosci. Res. | pmid:6195351 |
Prasad MR et al. | Kinetic evidence for two separate trans-2-enoyl CoA reductases in rat hepatic microsomes: NADPH-specific short chain- and NAD(P)H-dependent long chain-reductase. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6870879 |
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Yukioka M et al. | Transcribing chromatin is not preferentially enriched with acetylated histones. | 1983 | FEBS Lett. | pmid:6873281 |
Plesko MM et al. | Inhibition by sodium butyrate of enzyme induction by glucocorticoids and dibutyryl cyclic AMP. A role for the rapid form of histone acetylation. | 1983 | J. Biol. Chem. | pmid:6196355 |
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Belmont A and Nicolini C | The G1 period. Two cycles of chromatin conformational changes monitored by single cell dye intercalation. | 1983 | Cell Biophys. | pmid:6197177 |
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Bide RW and Dorward WJ | Excess rumen product anions in cattle. II. Toxic and lethal effects with butyrate. | 1983 | Can. J. Comp. Med. | pmid:6883190 |
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Bode J et al. | Nucleosomal particles open as the histone core becomes hyperacetylated. | 1983 | Eur. J. Biochem. | pmid:6218991 |
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Annunziato AT and Seale RL | Histone deacetylation is required for the maturation of newly replicated chromatin. | 1983 | J. Biol. Chem. | pmid:6226660 |
Loidl P et al. | Lack of correlation between histone H4 acetylation and transcription during the Physarum cell cycle. | 1983 Sep 29-Oct 5 | Nature | pmid:6621695 |
Vernay M and Marty J | Absorption and metabolism of butyric acid in rabbit hind gut. | 1984 | Comp Biochem Physiol A Comp Physiol | pmid:6141037 |
McCue PA et al. | Sodium butyrate induces histone hyperacetylation and differentiation of murine embryonal carcinoma cells. | 1984 | J. Cell Biol. | pmid:6141173 |
Hsu KH and Friedman H | Dexamethasone inhibition of DMSO-induced transglutaminase activity and differentiation of leukemic cells. | 1984 | Proc. Soc. Exp. Biol. Med. | pmid:6141568 |
Rupniak HT et al. | Characteristics of a new human neuroblastoma cell line which differentiates in response to cyclic adenosine 3':5'-monophosphate. | 1984 | Cancer Res. | pmid:6144383 |
Wagenmakers AJ and Veerkamp JH | Interaction of octanoate with branched-chain 2-oxo acid oxidation in rat and human muscle in vitro. | 1984 | Int. J. Biochem. | pmid:6479435 |
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Wintersberger E and Mudrak I | Sodium butyrate inhibits the synthesis of the transformation related protein p 53 in 3T6 mouse fibroblasts. | 1984 | FEBS Lett. | pmid:6319196 |
Kramer RE et al. | Induction of synthesis of mitochondrial steroidogenic enzymes of bovine adrenocortical cells by analogs of cyclic AMP. | 1984 | J. Biol. Chem. | pmid:6319383 |
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Casanova J et al. | Photoaffinity labeling of thyroid hormone nuclear receptors. Influence of n-butyrate and analysis of the half-lives of the 57,000 and 47,000 molecular weight receptor forms. | 1984 | J. Biol. Chem. | pmid:6090453 |
Garrè C et al. | Regulation of acetylcholinesterase expression in the K-562 cell line. | 1984 | Cancer Res. | pmid:6589044 |
Kyritsis A et al. | Effects of butyrate, retinol, and retinoic acid on human Y-79 retinoblastoma cells growing in monolayer cultures. | 1984 | J. Natl. Cancer Inst. | pmid:6590911 |
Irving CC et al. | Comparative carcinogenicity of N-butyl-N-(3-carboxypropyl)-nitrosamine and N-butyl-N-(4-hydroxybutyl)nitrosamine for the urinary bladder of (C57BL/6 X DBA/2)F1 mice. | 1984 | J. Natl. Cancer Inst. | pmid:6590920 |
Flatow U et al. | Butyrate prevents Harvey Sarcoma virus focus formation but permits oncogene expression. | 1984 | Cancer Lett. | pmid:6200208 |
McIntyre LJ and Kim YS | Effects of sodium butyrate and dimethylsulfoxide on human pancreatic tumor cell lines. | 1984 | Eur J Cancer Clin Oncol | pmid:6200329 |
Thomsen LL et al. | Intra-caecal short chain fatty acids are altered by dietary pectin in the rat. | 1984 | Digestion | pmid:6086434 |
Takimoto T et al. | Effects of chemical inducers on the Epstein-Barr virus cycle in epithelial/nasopharyngeal carcinoma hybrid cell line. | 1984 | ORL J. Otorhinolaryngol. Relat. Spec. | pmid:6087237 |
Goldman JE and Chiu FC | Dibutyryl cyclic AMP causes intermediate filament accumulation and actin reorganization in astrocytes. | 1984 | Brain Res. | pmid:6087982 |
Shively JM et al. | Depression of the synthesis of the intermediate and large forms of ribulose-1,5-bisphosphate carboxylase/oxygenase in Rhodopseudomonas capsulata. | 1984 | Arch. Microbiol. | pmid:6089690 |
Anisimová E et al. | Effects of n-butyrate and phorbol ester (TPA) on induction of Epstein-Barr virus antigens and cell differentiation. | 1984 | Arch. Virol. | pmid:6089703 |