| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Tumor Virus Infections | D014412 | 8 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Ovarian Neoplasms | D010051 | 10 associated lipids |
| Diabetic Ketoacidosis | D016883 | 16 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Insulinoma | D007340 | 28 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang C et al. | A survey of fermentation products and bacterial communities in corn silage produced in a bunker silo in China. | 2014 | Anim. Sci. J. | pmid:23638801 |
| Unno T et al. | Effect of dietary supplementation of (-)-epigallocatechin gallate on gut microbiota and biomarkers of colonic fermentation in rats. | 2014 | J. Nutr. Sci. Vitaminol. | pmid:25078378 |
| Vidrine K et al. | Resistant starch from high amylose maize (HAM-RS2) and dietary butyrate reduce abdominal fat by a different apparent mechanism. | 2014 | Obesity (Silver Spring) | pmid:23630079 |
| Liu J et al. | Sodium butyrate promotes the differentiation of rat bone marrow mesenchymal stem cells to smooth muscle cells through histone acetylation. | 2014 | PLoS ONE | pmid:25548915 |
| Vicente F et al. | Subclinical ketosis on dairy cows in transition period in farms with contrasting butyric acid contents in silages. | 2014 | ScientificWorldJournal | pmid:25525616 |
| Szymanowska-Powałowska D et al. | Biotechnological potential of Clostridium butyricum bacteria. | 2014 | Braz. J. Microbiol. | pmid:25477923 |
| Brocato J et al. | Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression. | 2014 | J. Biol. Chem. | pmid:25266719 |
| Kondo Y et al. | Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells. | 2014 | PLoS ONE | pmid:25084468 |
| Vargas JE et al. | Inhibition of HDAC increases the senescence induced by natural polyphenols in glioma cells. | 2014 | Biochem. Cell Biol. | pmid:25070040 |
| Ozadali K et al. | Synthesis and antimycobacterial activities of some new thiazolylhydrazone derivatives. | 2014 | Bioorg. Med. Chem. Lett. | pmid:24631185 |
| Shen H et al. | BMI1 reprogrammes histone acetylation and enhances c-fos pathway via directly binding to Zmym3 in malignant myeloid progression. | 2014 | J. Cell. Mol. Med. | pmid:24571310 |
| Karki P et al. | Yin Yang 1 is a repressor of glutamate transporter EAAT2, and it mediates manganese-induced decrease of EAAT2 expression in astrocytes. | 2014 | Mol. Cell. Biol. | pmid:24469401 |
| Pérez-Carro R et al. | Functional analysis and in vitro correction of splicing FAH mutations causing tyrosinemia type I. | 2014 | Clin. Genet. | pmid:23895425 |
| Miltko R et al. | Can fungal zoospores be the source of energy for the rumen protozoa Eudiplodinium maggii? | 2014 | Anaerobe | pmid:24012688 |
| Bilgraer R et al. | A new approach combining LC-MS and multivariate statistical analysis for revealing changes in histone modification levels. | 2014 | Mol Biosyst | pmid:25167371 |
| Xu G et al. | SAHA regulates histone acetylation, Butyrylation, and protein expression in neuroblastoma. | 2014 | J. Proteome Res. | pmid:25160476 |
| Khan S and Jena G | Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-β1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats. | 2014 | Food Chem. Toxicol. | pmid:25158305 |
| Moeinian M et al. | Beneficial effect of butyrate, Lactobacillus casei and L-carnitine combination in preference to each in experimental colitis. | 2014 | World J. Gastroenterol. | pmid:25152589 |
| Chou AH et al. | Polyglutamine-expanded ataxin-3 impairs long-term depression in Purkinje neurons of SCA3 transgenic mouse by inhibiting HAT and impairing histone acetylation. | 2014 | Brain Res. | pmid:25139423 |
| Reindl A et al. | Enumeration of clostridia in goat milk using an optimized membrane filtration technique. | 2014 | J. Dairy Sci. | pmid:25129496 |
| Kanski R et al. | Histone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament network. | 2014 | J. Cell. Sci. | pmid:25128567 |
| Lee JM et al. | Direct hydrogenation of biomass-derived butyric acid to n-butanol over a ruthenium-tin bimetallic catalyst. | 2014 | ChemSusChem | pmid:25123894 |
| Lopez CA et al. | Collateral damage: microbiota-derived metabolites and immune function in the antibiotic era. | 2014 | Cell Host Microbe | pmid:25121745 |
| Cho HJ and Song MJ | A gammaherpesvirus establishes persistent infection in neuroblastoma cells. | 2014 | Mol. Cells | pmid:25092213 |
| Li S et al. | High-grain diets suppress ruminal tissue abundance of angiopoietin-like protein 4 in cattle. | 2014 | J. Anim. Sci. | pmid:25085388 |
| Tiwari P and Gupta KP | Modulation of miR-203 and its regulators as a function of time during the development of 7, 12 dimethylbenz [a] anthracene induced mouse skin tumors in presence or absence of the antitumor agents. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24792773 |
| Pasvolsky R et al. | Butyric acid released during milk lipolysis triggers biofilm formation of Bacillus species. | 2014 | Int. J. Food Microbiol. | pmid:24801271 |
| Maggio A et al. | Daily sodium butyrate enema for the prevention of radiation proctitis in prostate cancer patients undergoing radical radiation therapy: results of a multicenter randomized placebo-controlled dose-finding phase 2 study. | 2014 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:24803033 |
| Ellis JT et al. | Microbial bioproducts from cheese whey through fermentation with wastewater sludge Clostridium isolates. | 2014 | Can. J. Microbiol. | pmid:24898684 |
| Ochiai K and Kurita-Ochiai T | [Alternative effects of a metabolic by-product, butyric acid, produced by oral anaerobes]. | 2014 | Nippon Yakurigaku Zasshi | pmid:25109521 |
| Liu W et al. | Effects of dietary microencapsulated sodium butyrate on growth, intestinal mucosal morphology, immune response and adhesive bacteria in juvenile common carp (Cyprinus carpio) pre-fed with or without oxidised oil. | 2014 | Br. J. Nutr. | pmid:24774835 |
| Ladirat SE et al. | Exploring the effects of galacto-oligosaccharides on the gut microbiota of healthy adults receiving amoxicillin treatment. | 2014 | Br. J. Nutr. | pmid:24925303 |
| Zhou X et al. | Comparison of the effects of high energy carbon heavy ion irradiation and Eucommia ulmoides Oliv. on biosynthesis butyric acid efficiency in Clostridium tyrobutyricum. | 2014 | Bioresour. Technol. | pmid:24704888 |
| Jang YS et al. | Metabolic engineering of Clostridium acetobutylicum for butyric acid production with high butyric acid selectivity. | 2014 | Metab. Eng. | pmid:24704310 |
| Syngiridis K et al. | Favouring butyrate production for a new generation biofuel by acidogenic glucose fermentation using cells immobilised on γ-alumina. | 2014 | Bioresour. Technol. | pmid:24690582 |
| Sarkar A et al. | Hippocampal HDAC4 contributes to postnatal fluoxetine-evoked depression-like behavior. | 2014 | Neuropsychopharmacology | pmid:24663010 |
| Csikó G et al. | Effects of dietary sodium butyrate on hepatic biotransformation and pharmacokinetics of erythromycin in chickens. | 2014 | J. Vet. Pharmacol. Ther. | pmid:24628435 |
| Han A et al. | Possible additional antidepressant-like mechanism of sodium butyrate: targeting the hippocampus. | 2014 | Neuropharmacology | pmid:24607816 |
| Park HG et al. | Repeated treatment with electroconvulsive seizures induces HDAC2 expression and down-regulation of NMDA receptor-related genes through histone deacetylation in the rat frontal cortex. | 2014 | Int. J. Neuropsychopharmacol. | pmid:24606669 |
| Aguilar EC et al. | Butyrate impairs atherogenesis by reducing plaque inflammation and vulnerability and decreasing NFκB activation. | 2014 | Nutr Metab Cardiovasc Dis | pmid:24602606 |
| Sabra W et al. | Improved n-butanol production by a non-acetone producing Clostridium pasteurianum DSMZ 525 in mixed substrate fermentation. | 2014 | Appl. Microbiol. Biotechnol. | pmid:24584460 |
| Blank M et al. | Basolateral amygdala activity is required for enhancement of memory consolidation produced by histone deacetylase inhibition in the hippocampus. | 2014 | Neurobiol Learn Mem | pmid:24583371 |
| Possebom G et al. | Esterification of fatty acids by Penicillium crustosum lipase in a membrane reactor. | 2014 | J. Sci. Food Agric. | pmid:24578290 |
| Zhang Z et al. | Sodium butyrate facilitates reprogramming by derepressing OCT4 transactivity at the promoter of embryonic stem cell-specific miR-302/367 cluster. | 2014 | Cell Reprogram | pmid:24568633 |
| Bolhari B et al. | Acid and microhardness of mineral trioxide aggregate and mineral trioxide aggregate-like materials. | 2014 | J Endod | pmid:24565666 |
| Kumar P et al. | All-trans retinoic acid and sodium butyrate enhance natriuretic peptide receptor a gene transcription: role of histone modification. | 2014 | Mol. Pharmacol. | pmid:24714214 |
| Dos Santos MP et al. | In vitro antitumor effect of sodium butyrate and zoledronic acid combined with traditional chemotherapeutic drugs: a paradigm of synergistic molecular targeting in the treatment of Ewing sarcoma. | 2014 | Oncol. Rep. | pmid:24316794 |
| Lee SM et al. | Digital mRNA profiling of N-glycosylation gene expression in recombinant Chinese hamster ovary cells treated with sodium butyrate. | 2014 | J. Biotechnol. | pmid:24333461 |
| Dostal A et al. | Iron supplementation promotes gut microbiota metabolic activity but not colitis markers in human gut microbiota-associated rats. | 2014 | Br. J. Nutr. | pmid:24555487 |
| Khan S and Jena GB | Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: study in juvenile diabetic rat. | 2014 | Chem. Biol. Interact. | pmid:24530320 |
| Ferreira AC et al. | Histone deacetylase inhibitor prevents cell growth in Burkitt's lymphoma by regulating PI3K/Akt pathways and leads to upregulation of miR-143, miR-145, and miR-101. | 2014 | Ann. Hematol. | pmid:24577510 |
| Dengler F et al. | Bicarbonate-dependent transport of acetate and butyrate across the basolateral membrane of sheep rumen epithelium. | 2014 | Acta Physiol (Oxf) | pmid:23927569 |
| Meehan CJ and Beiko RG | A phylogenomic view of ecological specialization in the Lachnospiraceae, a family of digestive tract-associated bacteria. | 2014 | Genome Biol Evol | pmid:24625961 |
| Yan SF et al. | HDAC inhibitor sodium butyrate augments the MEF2C enhancement of Nampt expression under hypoxia. | 2014 | Curr. Pharm. Des. | pmid:23888946 |
| Pan Y et al. | Potential usefulness of baculovirus-mediated sodium-iodide symporter reporter gene as non-invasively gene therapy monitoring in liver cancer cells: an in vitro evaluation. | 2014 | Technol. Cancer Res. Treat. | pmid:23919394 |
| Drees J et al. | Butyrate stimulates the early process of the osteogenic differentiation but inhibits the biomineralization in dental follicle cells (DFCs). | 2014 | Odontology | pmid:23836050 |
| Molina S et al. | Antiproliferative effect of alkylglycerols as vehicles of butyric acid on colon cancer cells. | 2013 Oct-Nov | Chem. Phys. Lipids | pmid:23973778 |
| Wu Z et al. | Histone deacetylase inhibitors suppress the growth of human osteosarcomas in vitro and in vivo. | 2013 Oct-Dec | J BUON | pmid:24344034 |
| Tigunova EA et al. | [Alternative type of fuel--biobutanol]. | 2013 Nov-Dec | Tsitol. Genet. | pmid:24437198 |
| Misaghi S et al. | Resilient immortals, characterizing and utilizing Bax/Bak deficient Chinese hamster ovary (CHO) cells for high titer antibody production. | 2013 May-Jun | Biotechnol. Prog. | pmid:23596153 |
| Okazaki Y et al. | Burdock fermented by Aspergillus awamori elevates cecal Bifidobacterium, and reduces fecal deoxycholic acid and adipose tissue weight in rats fed a high-fat diet. | 2013 | Biosci. Biotechnol. Biochem. | pmid:23291748 |
| Humphreys KJ et al. | Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. | 2013 | Mol. Carcinog. | pmid:22308110 |
| Rochus K et al. | Highly viscous guar gum shifts dietary amino acids from metabolic use to fermentation substrate in domestic cats. | 2013 | Br. J. Nutr. | pmid:22877608 |
| Cantoni S et al. | Sodium butyrate inhibits platelet-derived growth factor-induced proliferation and migration in pulmonary artery smooth muscle cells through Akt inhibition. | 2013 | FEBS J. | pmid:23463962 |
| Muhammad A et al. | Novel fluorescent membrane for metronidazole sensing prepared by covalent immobilization of a pyrenebutyric acid derivative. | 2013 | J Fluoresc | pmid:23471624 |
| Tirandaz H and Mohammadi E | Efficient tumor targeting by anaerobic butyrate-producing bacteria. | 2013 | Med. Hypotheses | pmid:23410499 |
| Cuadrado-Tejedor M et al. | Phenylbutyrate is a multifaceted drug that exerts neuroprotective effects and reverses the Alzheimer´s disease-like phenotype of a commonly used mouse model. | 2013 | Curr. Pharm. Des. | pmid:23448463 |
| Raybuck JD et al. | The histone deacetylase inhibitor sodium butyrate modulates acquisition and extinction of cocaine-induced conditioned place preference. | 2013 | Pharmacol. Biochem. Behav. | pmid:23454534 |
| Wang HG et al. | Anticancer effects of sodium butyrate on hepatocellular carcinoma cells in vitro. | 2013 | Int. J. Mol. Med. | pmid:23440283 |
| Kedia G et al. | Addressing the challenge of optimum polyhydroxyalkanoate harvesting: monitoring real time process kinetics and biopolymer accumulation using dielectric spectroscopy. | 2013 | Bioresour. Technol. | pmid:23500571 |
| Fialova B et al. | Effect of histone deacetylase and DNA methyltransferase inhibitors on the expression of the androgen receptor gene in androgen-independent prostate cancer cell lines. | 2013 | Oncol. Rep. | pmid:23503510 |
| Ayers LW et al. | Freezing to the predator odor 2,4,5 dihydro 2,5 trimethylthiazoline (TMT) is disrupted by olfactory bulb removal but not trigeminal deafferentation. | 2013 | Behav. Brain Res. | pmid:23831303 |
| Liang X et al. | Sodium butyrate protects against severe burn-induced remote acute lung injury in rats. | 2013 | PLoS ONE | pmid:23874764 |
| Wiese BI et al. | Short communication: Interrelationship between butyrate and glucose supply on butyrate and glucose oxidation by ruminal epithelial preparations. | 2013 | J. Dairy Sci. | pmid:23810600 |
| Cueno ME et al. | Butyric acid retention in gingival tissue induces oxidative stress in jugular blood mitochondria. | 2013 | Cell Stress Chaperones | pmid:23397230 |
| AteÅŸ S et al. | Enhanced ethyl butyrate production using immobilized lipase. | 2013 | Artif Cells Nanomed Biotechnol | pmid:23305408 |
| Pappu VK et al. | Butyric acid esterification kinetics over Amberlyst solid acid catalysts: the effect of alcohol carbon chain length. | 2013 | Bioresour. Technol. | pmid:23380294 |
| Sharma P et al. | Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site. | 2013 | Arch. Biochem. Biophys. | pmid:23149273 |
| Lim JH et al. | Refactoring redox cofactor regeneration for high-yield biocatalysis of glucose to butyric acid in Escherichia coli. | 2013 | Bioresour. Technol. | pmid:23127832 |
| Zhang Z and Wu WS | Sodium butyrate promotes generation of human induced pluripotent stem cells through induction of the miR302/367 cluster. | 2013 | Stem Cells Dev. | pmid:23534850 |
| Coskun T et al. | Carbodeoxygenation of biomass: the carbonylation of glycerol and higher polyols to monocarboxylic acids. | 2013 | Chemistry | pmid:23536394 |
| Ximenes JC et al. | Valproic acid: an anticonvulsant drug with potent antinociceptive and anti-inflammatory properties. | 2013 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:23584602 |
| Stojcev Z et al. | Early treatment and prevention of the radiation proctitis--composite enemas containing sodium butyrate. | 2013 | Int J Colorectal Dis | pmid:23516076 |
| Nör C et al. | The histone deacetylase inhibitor sodium butyrate promotes cell death and differentiation and reduces neurosphere formation in human medulloblastoma cells. | 2013 | Mol. Neurobiol. | pmid:23516101 |
| Chen HC et al. | Preparation of highly conjugated water-dispersible graphene-butyric acid for the enhancement of electron transfer within polyamic acid-benzoxazole: potential applications in electrochemical sensing. | 2013 | Biosens Bioelectron | pmid:23517822 |
| Sharma B and Sharma PM | Arsenic toxicity induced endothelial dysfunction and dementia: pharmacological interdiction by histone deacetylase and inducible nitric oxide synthase inhibitors. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23921152 |
| Tashiro Y et al. | A novel production process for optically pure L-lactic acid from kitchen refuse using a bacterial consortium at high temperatures. | 2013 | Bioresour. Technol. | pmid:23978480 |
| Jang YS et al. | Metabolic engineering of Clostridium acetobutylicum for enhanced production of butyric acid. | 2013 | Appl. Microbiol. Biotechnol. | pmid:24013291 |
| Stefaniková A et al. | ABT-737 accelerates butyrate-induced death of HL-60 cells. Involvement of mitochondrial apoptosis pathway. | 2013 | Gen. Physiol. Biophys. | pmid:23940089 |
| Hao PP et al. | Isolation of EpCAM(+)/CD133 (-) hepatic progenitor cells. | 2013 | Mol. Cells | pmid:24293012 |
| Venkataramanan KP et al. | The Clostridium small RNome that responds to stress: the paradigm and importance of toxic metabolite stress in C. acetobutylicum. | 2013 | BMC Genomics | pmid:24299206 |
| Grousseau E et al. | Impact of sustaining a controlled residual growth on polyhydroxybutyrate yield and production kinetics in Cupriavidus necator. | 2013 | Bioresour. Technol. | pmid:24035890 |
| Cuervo A et al. | Fiber from a regular diet is directly associated with fecal short-chain fatty acid concentrations in the elderly. | 2013 | Nutr Res | pmid:24074739 |
| Dükkancı M and Gündüz G | Sonolytic degradation of butyric acid in aqueous solutions. | 2013 | J. Environ. Manage. | pmid:24029459 |
| Sánchez-Tena S et al. | Green tea phenolics inhibit butyrate-induced differentiation of colon cancer cells by interacting with monocarboxylate transporter 1. | 2013 | Biochim. Biophys. Acta | pmid:23994611 |
| Damiani R et al. | Enhancement of human thyrotropin synthesis by sodium butyrate addition to serum-free CHO cell culture. | 2013 | Appl. Biochem. Biotechnol. | pmid:23996121 |
| Mattace Raso G et al. | Effects of sodium butyrate and its synthetic amide derivative on liver inflammation and glucose tolerance in an animal model of steatosis induced by high fat diet. | 2013 | PLoS ONE | pmid:23861927 |
| Zhang L et al. | Genome-wide screening for genes associated with valproic acid sensitivity in fission yeast. | 2013 | PLoS ONE | pmid:23861937 |
| Kumar M et al. | Role of extracellular cues to trigger the metabolic phase shifting from acidogenesis to solventogenesis in Clostridium acetobutylicum. | 2013 | Bioresour. Technol. | pmid:23612162 |
| Franco W and Pérez-DÃaz IM | Microbial interactions associated with secondary cucumber fermentation. | 2013 | J. Appl. Microbiol. | pmid:23013318 |