butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Authors Title Published Journal PubMed Link
Sjöholm A Sodium butyrate inhibits rat insulinoma cell proliferation without affecting the cellular insulin content or insulin release. 1993 Anticancer Drugs pmid:8490204
Corra S et al. Modification of antigen expression in human and hamster pancreatic cancer cell lines induced by sodium butyrate. 1993 Teratog., Carcinog. Mutagen. pmid:7905674
Schmidt JE and Ahring BK Effects of hydrogen and formate on the degradation of propionate and butyrate in thermophilic granules from an upflow anaerobic sludge blanket reactor. 1993 Appl. Environ. Microbiol. pmid:8368842
Holtenius K and Hydbring E Somatostatin inhibits butyrate-induced insulin secretion in sheep. 1993 Acta Vet Scand Suppl pmid:7901983
Nishii Y et al. n-Butyrate enhances induction of thyroid hormone-responsive nuclear protein. 1993 Endocr. J. pmid:7951517
Matsunaga N et al. Inhibitory effect of volatile fatty acids on GRF-induced GH secretion in sheep. 1993 Endocr. J. pmid:7951518
Perry CA et al. Analysis of nucleosome assembly and histone exchange using antibodies specific for acetylated H4. 1993 Biochemistry pmid:7504954
Oster T et al. Induction of recombinant human gamma-glutamyl transferase by sodium butyrate in transfected V79 and CHO Chinese hamster cells. 1993 Biochem. Biophys. Res. Commun. pmid:8099285
Reeder JA et al. Sodium butyrate differentially modulates plasminogen activator inhibitor type-1, urokinase plasminogen activator, and its receptor in a human colon carcinoma cell. 1993 Teratog., Carcinog. Mutagen. pmid:8102211
Frommel TO et al. Variable effects of sodium butyrate on the expression and function of the MDR1 (P-glycoprotein) gene in colon carcinoma cell lines. 1993 Int. J. Cancer pmid:8103760
Piñeiro M et al. Transcription of mononucleosomal particles acetylated in the presence of n-butyrate. 1993 Mol. Biol. Rep. pmid:8232292
Finnie IA et al. Ileal and colonic epithelial metabolism in quiescent ulcerative colitis: increased glutamine metabolism in distal colon but no defect in butyrate metabolism. 1993 Gut pmid:8244143
Roediger WE Colonic epithelial metabolism in ulcerative colitis. 1993 Gut pmid:8244158
Gürtler H et al. Acute metabolic and hormonal effects of intravenously administered sodium n-butyrate in untreated and alloxan-diabetic sheep. 1993 Zentralbl Veterinarmed A pmid:8212952
Sperker B et al. The expression of human plasma cholesteryl-ester-transfer protein in HepG2 cells is induced by sodium butyrate. Quantification of low mRNA levels by polymerase chain reaction. 1993 Eur. J. Biochem. pmid:8281947
Halvorsen YD et al. Vasodilation of rat retinal microvessels induced by monobutyrin. Dysregulation in diabetes. 1993 J. Clin. Invest. pmid:8254042
Planchon P et al. Differential elimination of synthetic butyric triglycerides in vivo: a pharmacokinetic study. 1993 J Pharm Sci pmid:8254490
Perry CA et al. Parental nucleosomes segregated to newly replicated chromatin are underacetylated relative to those assembled de novo. 1993 Biochemistry pmid:8257695
Carraro S et al. [Influence of sodium butyrate intake on murine colonic carcinogenesis]. 1993 Medicina (B Aires) pmid:8295530
Dong QG et al. Isolation of a mitomycin-resistant human lung adenocarcinoma cell subline to investigate the modulation by sodium butyrate of cell growth and drug resistance. 1993 Anticancer Drugs pmid:8298162
Fernandez-Mejia C and Davidson MB Effect of sodium butyrate on glucose transport and glucose-phosphorylating enzymes in RIN-m5F cells. 1993 Pancreas pmid:8302795
Yabushita H and Sartorelli AC Effects of sodium butyrate, dimethylsulfoxide and dibutyryl cAMP on the poorly differentiated ovarian adenocarcinoma cell line AMOC-2. 1993 Oncol. Res. pmid:8305743
Laughlin MA et al. Sodium butyrate treatment of cells latently infected with HIV-1 results in the expression of unspliced viral RNA. 1993 Virology pmid:8372431
Barnard JA and Warwick G Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells. 1993 Cell Growth Differ. pmid:8373733
Nishina Y et al. The induction of jun genes during the reversible changes induced with sodium butyrate on the differentiation of F9 cells. 1993 Exp. Cell Res. pmid:8375477
Griner RD et al. The role of short chain fatty acid substrates in aerobic and glycolytic metabolism in primary cultures of renal proximal tubule cells. 1993 In Vitro Cell. Dev. Biol. Anim. pmid:8376317
Heruth DP et al. Sodium butyrate causes an increase in the block to transcriptional elongation in the c-myc gene in SW837 rectal carcinoma cells. 1993 J. Biol. Chem. pmid:8376401
Darcy-Vrillon B et al. Metabolic characteristics of pig colonocytes after adaptation to a high fiber diet. 1993 J. Nutr. pmid:8381478
Gaudet SJ et al. Differential regulation of arylamine and arylalkylamine N-acetyltransferases in human retinoblastoma (Y-79) cells. 1993 Neurochem. Int. pmid:8382984
Khan MZ et al. Induction of phenotypic changes in SCLC cell lines in vitro by hexamethylene bisacetamide, sodium butyrate, and cyclic AMP. 1993 Ann. Oncol. pmid:8394737
Rius C et al. Differential modulation of the expression of the intermediate filament proteins vimentin and nuclear lamins A and C by differentiation inducers in human myeloid leukemia (U-937, HL-60) cells. 1993 Exp. Cell Res. pmid:8395394
Telfer JF and Green CD Placental alkaline phosphatase activity is inversely related to cell growth rate in HeLaS3 cervical cancer cells. 1993 FEBS Lett. pmid:8396040
Hague A et al. Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer. 1993 Int. J. Cancer pmid:8397167
Taggart M and Wray S Simultaneous measurement of intracellular pH and contraction in uterine smooth muscle. 1993 Pflugers Arch. pmid:8351202
Mollinedo F et al. Differences in expression of transcription factor AP-1 in human promyelocytic HL-60 cells during differentiation towards macrophages versus granulocytes. 1993 Biochem. J. pmid:8363564
Karuri AR et al. Selective cellular acidification and toxicity of weak organic acids in an acidic microenvironment. 1993 Br. J. Cancer pmid:8260358
Iwai SA et al. Changes in Hox1.6, c-jun, and Oct-3 gene expressions are associated with teratocarcinoma F9 cell differentiation in three different ways of induction. 1993 Exp. Cell Res. pmid:8453995
Stark AH and Madar Z In vitro production of short-chain fatty acids by bacterial fermentation of dietary fiber compared with effects of those fibers on hepatic sterol synthesis in rats. 1993 J. Nutr. pmid:8263612
Wischmeyer P et al. Chronic pouchitis after ileal pouch-anal anastomosis: responses to butyrate and glutamine suppositories in a pilot study. 1993 Mayo Clin. Proc. pmid:8412364
Diener M et al. Effect of short-chain fatty acids on cell volume and intracellular pH in rat distal colon. 1993 Pflugers Arch. pmid:8414909
Dohi T et al. Induction of the fundic mucosa-specific glycolipid with dimethylformamide in gastric-cancer cell lines. 1993 Int. J. Cancer pmid:8416198
Sommerville J et al. Histone H4 acetylation and transcription in amphibian chromatin. 1993 J. Cell Biol. pmid:8421048
Salvador V et al. Sugar composition of dietary fibre and short-chain fatty acid production during in vitro fermentation by human bacteria. 1993 Br. J. Nutr. pmid:8399101
Herz F Divergent effects of butyrate on the alkaline phosphatases of SW-620 cells. 1993 Biochim. Biophys. Acta pmid:8422435
Blau CA et al. Fetal hemoglobin induction with butyric acid: efficacy and toxicity. 1993 Blood pmid:8422469
Gerharz CD et al. Modulation of invasive potential in different clonal subpopulations of a rat rhabdomyosarcoma cell line (BA-HAN-1) by differentiation induction. 1993 Clin. Exp. Metastasis pmid:8422707
Datti A and Dennis JW Regulation of UDP-GlcNAc:Gal beta 1-3GalNAc-R beta 1-6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) in Chinese hamster ovary cells. 1993 J. Biol. Chem. pmid:8383671
Wind JC et al. Stimulation of calcitonin/CGRP-I and CGRP-II gene expression by dibutyryl cAMP in a human medullary thyroid carcinoma (TT) cell line. 1993 Mol. Cell. Endocrinol. pmid:8386116
Sakamoto K et al. Relative mitogenic activities of wild-type and retinoblastoma binding-defective SV40 T antigens in serum-deprived and senescent human diploid fibroblasts. 1993 Oncogene pmid:8390037
Polack A et al. Regulatory elements in the immunoglobulin kappa locus induce c-myc activation and the promoter shift in Burkitt's lymphoma cells. 1993 EMBO J. pmid:8404859
Lavelle D et al. Fetal hemoglobin reactivation in baboon and man: a short perspective. 1993 Am. J. Hematol. pmid:7677951
Pack R et al. Isolation, biochemical characterization, long-term culture, and phenotype modulation of oval cells from carcinogen-fed rats. 1993 Exp. Cell Res. pmid:7679995
Fibach E et al. Enhanced fetal hemoglobin production by phenylacetate and 4-phenylbutyrate in erythroid precursors derived from normal donors and patients with sickle cell anemia and beta-thalassemia. 1993 Blood pmid:7691251
Thurnher M et al. Persistent repression of a functional allele can be responsible for galactosyltransferase deficiency in Tn syndrome. 1993 J. Clin. Invest. pmid:7683697
Albina JE and Mastrofrancesco B Modulation of glucose metabolism in macrophages by products of nitric oxide synthase. 1993 Am. J. Physiol. pmid:7687412
Aggarwal BB et al. Regulation of two forms of the TNF receptors by phorbol ester and dibutyryl cyclic adenosine 3',5'-monophosphate in human histiocytic lymphoma cell line U-937. 1993 Lymphokine Cytokine Res. pmid:7688579
Lee CY et al. Bench-scale production of acrylamide using the resting cells of Brevibacterium sp. CH2 in a fed-batch reactor. 1993 Enzyme Microb. Technol. pmid:7764257
Horvath PJ et al. Differential effect of butyrate on lipids of human colon cancer cells. 1993 Nutr Cancer pmid:8108277
Fedotov VP et al. [The possible participation of gap junctions in the realization of the effects of stimulators of secretory processes in the hypophysis]. 1993 Biull Eksp Biol Med pmid:8123822
Souleimani A and Asselin C Regulation of c-myc expression by sodium butyrate in the colon carcinoma cell line Caco-2. 1993 FEBS Lett. pmid:8325387
Komatsu N et al. Establishment and characterization of an erythropoietin-dependent subline, UT-7/Epo, derived from human leukemia cell line, UT-7. 1993 Blood pmid:8329702
Wiekowski M et al. Requirements for promoter activity in mouse oocytes and embryos distinguish paternal pronuclei from maternal and zygotic nuclei. 1993 Dev. Biol. pmid:8365573
Dimitrov S et al. Chromatin transitions during early Xenopus embryogenesis: changes in histone H4 acetylation and in linker histone type. 1993 Dev. Biol. pmid:8224538
Chen Z et al. A serum-free medium for hybridoma cell culture. 1993 Cytotechnology pmid:7764121
Desai TK et al. Potentiation of butyrate-induced differentiation in human colon tumor cells by deoxycholate. 1993 Cancer Lett. pmid:8513444
Khochbin S and Wolffe AP Developmental regulation and butyrate-inducible transcription of the Xenopus histone H1(0) promoter. 1993 Gene pmid:8514185
Ford R et al. Modulation of SPARC expression during butyrate-induced terminal differentiation of cultured human keratinocytes: regulation via a TGF-beta-dependent pathway. 1993 Exp. Cell Res. pmid:8500547
Souleimani A and Asselin C Regulation of C-fos expression by sodium butyrate in the human colon carcinoma cell line Caco-2. 1993 Biochem. Biophys. Res. Commun. pmid:8503924
Van Lier JB et al. Effects of acetate, propionate, and butyrate on the thermophilic anaerobic degradation of propionate by methanogenic sludge and defined cultures. 1993 Appl. Environ. Microbiol. pmid:8476278
Hume ID et al. Acetate, butyrate and proline uptake in the caecum and colon of prairie voles (Microtus ochrogaster). 1993 J. Exp. Biol. pmid:8478602
Huhtanen P et al. Effect of increasing ruminal butyrate on milk yield and blood constituents in dairy cows fed a grass silage-based diet. 1993 J. Dairy Sci. pmid:8486840
Kight CE and Fleming SE Nutrient oxidation by rat intestinal epithelial cells is concentration dependent. 1993 J. Nutr. pmid:8487099
Yoshida M et al. Effect of hexafluoro-1,25-dihydroxyvitamin D3 and sodium butyrate combination on differentiation and proliferation of HL-60 leukemia cells. 1992 Nov-Dec Anticancer Res. pmid:1363510
Rocchi P et al. Growth inhibitory and differentiating effects of sodium butyrate on human neuroblastoma cells in culture. 1992 May-Jun Anticancer Res. pmid:1622149
Boulikas T Poly(ADP-ribose) synthesis in blocked and damaged cells and its relation to carcinogenesis. 1992 May-Jun Anticancer Res. pmid:1535771
Gibson PR et al. Contrasting effects of butyrate on the expression of phenotypic markers of differentiation in neoplastic and non-neoplastic colonic epithelial cells in vitro. 1992 Mar-Apr J. Gastroenterol. Hepatol. pmid:1571499
Kalachniuk GI et al. [Glutamine metabolism by rumen microorganisms: effect of monensin]. 1992 Jul-Aug Ukr. Biokhim. Zh. pmid:1360177
Nachtigal MW et al. Chorionic gonadotrophin and c-myc expression in growing and growth-inhibited (intermediate) trophoblasts. 1992 Jul-Aug Placenta pmid:1438085
Friedel D and Levine GM Effect of short-chain fatty acids on colonic function and structure. 1992 Jan-Feb JPEN J Parenter Enteral Nutr pmid:1738211
Scheppach W et al. Effect of short-chain fatty acids on the human colonic mucosa in vitro. 1992 Jan-Feb JPEN J Parenter Enteral Nutr pmid:1738218
Duncan CE and Tasman-Jones C The ion exchange properties of human post-mortem caecal and colonic mucus: the effect of sodium butyrate. 1992 Jan-Feb J. Gastroenterol. Hepatol. pmid:1543870
Witte MM et al. Repression of SV40 T oncoprotein expression by DMSO. 1992 J. Cell. Physiol. pmid:1373148
Tsukamoto A et al. Increased assembly of cytoskeletal proteins associated with the transformation of human liver cells into fibroblast-like cells. 1992 Experientia pmid:1376281
Dyson JE et al. The effect of sodium butyrate on the growth characteristics of human cervix tumour cells. 1992 Br. J. Cancer pmid:1377482
Rius C and Aller P Vimentin expression as a late event in the in vitro differentiation of human promonocytic cells. 1992 J. Cell. Sci. pmid:1352781
Tucker WB et al. Sodium bicarbonate or multielement buffer via diet or rumen: effects on performance and acid-base status of lactating cows. 1992 J. Dairy Sci. pmid:1333497
Sklan D et al. Fatty acids, calcium soaps of fatty acids, and cottonseeds fed to high yielding cows. 1992 J. Dairy Sci. pmid:1452851
Tung RS et al. In vitro effects of the thiopeptide A10255 on ruminal fermentation and microbial populations. 1992 J. Dairy Sci. pmid:1452854
Wang G et al. Transforming growth factor-beta 1 acts cooperatively with sodium n-butyrate to induce differentiation of normal human keratinocytes. 1992 Exp. Cell Res. pmid:1727055
López-Rodas G et al. Enzymes involved in the dynamic equilibrium of core histone acetylation of Physarum polycephalum. 1992 FEBS Lett. pmid:1730297
Lutter LC et al. Effects of histone acetylation on chromatin topology in vivo. 1992 Mol. Cell. Biol. pmid:1406675
Chiofalo V et al. Influence of the method of forage conservation on feeding behaviour, intake and characteristics of reticulo-rumen content, in sheep fed ad libitum. 1992 Reprod. Nutr. Dev. pmid:1418399
Suzuki M et al. [Production of CA125 in cell lines derived from human ovarian carcinoma: in relation to the cell cycle]. 1992 Nippon Sanka Fujinka Gakkai Zasshi pmid:1506733
deFazio A et al. Effect of sodium butyrate on estrogen receptor and epidermal growth factor receptor gene expression in human breast cancer cell lines. 1992 J. Biol. Chem. pmid:1517234
Seagrave JC et al. Intracellular pH changes induced by exposure to weak acids and bases in submandibular cells of early postnatal rats. 1992 Arch. Oral Biol. pmid:1384459
Staiano-Coico L and Higgins PJ Cell shape changes during transition of basal keratinocytes to mature enucleate-cornified envelopes: modulation of terminal differentiation by fibronectin. 1992 Exp. Cell Res. pmid:1612118
Scheppach W et al. Effect of butyrate enemas on the colonic mucosa in distal ulcerative colitis. 1992 Gastroenterology pmid:1612357
Ichikawa K et al. Heat shock decreases nuclear transport of 3,5,3'-triiodo-L-thyronine in clone 9 cells. 1992 Endocrinology pmid:1547743
Klehr D et al. Scaffold-attached regions (SAR elements) mediate transcriptional effects due to butyrate. 1992 Biochemistry pmid:1554707
Gamet L et al. Effects of short-chain fatty acids on growth and differentiation of the human colon-cancer cell line HT29. 1992 Int. J. Cancer pmid:1521915