butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Arundel CM and Leith JT | Effects of nucleoside analogs and sodium butyrate on recovery from potentially lethal X ray damage in human colon tumor cells. | 1987 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:2435688 |
Sairenji T et al. | Immune response to intermediate filament-associated, Epstein-Barr virus-induced early antigen. | 1987 | J. Immunol. | pmid:2435803 |
Rowe M et al. | Monoclonal antibodies to the latent membrane protein of Epstein-Barr virus reveal heterogeneity of the protein and inducible expression in virus-transformed cells. | 1987 | J. Gen. Virol. | pmid:2438376 |
Addicks WJ et al. | Validation of a flow-through diffusion cell for use in transdermal research. | 1987 | Pharm. Res. | pmid:3509887 |
Dvorak AM et al. | Beige mouse mast cells generated in vitro: ultrastructural analysis of maturation induced by sodium butyrate and of IgE-mediated, antigen-dependent degranulation. | 1987 | Int. Arch. Allergy Appl. Immunol. | pmid:3570497 |
Bijman JT et al. | Modulation of placental alkaline phosphatase activity and cytokeratins in human HN-1 cells by butyrate, retinoic acid, catecholamines and histamine. | 1987 | Br. J. Cancer | pmid:2444242 |
Friedman J et al. | Modulation of carcinoembryonic antigen release by HT-29 colon carcinoma line in the presence of different agents. | 1987 | Experientia | pmid:2444456 |
Hanamura T et al. | Human colony-stimulating factor-producing lung cancer tissue releases a differentiation-inducing factor for human leukemic cells. | 1987 | Leukemia | pmid:2444832 |
Czerniak B et al. | Modification of Ha-ras oncogene p21 expression and cell cycle progression in the human colonic cancer cell line HT-29. | 1987 | Cancer Res. | pmid:3105868 |
Kaneko Y et al. | Effects of teleocidin on the morphology and c-myc expression of hepatoma cells which are not inhibited by protein kinase antagonists. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3109417 |
Clarke DO and Brown NA | Valproic acid teratogenesis and embryonic lipid metabolism. | 1987 | Arch. Toxicol. Suppl. | pmid:3115231 |
Nishigori C and Takebe H | Sodium butyrate stimulates cellular recovery from UV damage in xeroderma pigmentosum cells belonging to complementation group F. | 1987 | Jpn. J. Cancer Res. | pmid:3117749 |
Conway JG et al. | Role of fatty acyl coenzyme A oxidase in the efflux of oxidized glutathione from perfused livers of rats treated with the peroxisome proliferator nafenopin. | 1987 | Cancer Res. | pmid:3621175 |
McNeil NI et al. | Mucosal surface pH of the large intestine of the rat and of normal and inflamed large intestine in man. | 1987 | Gut | pmid:3623217 |
Harris MG et al. | Flexure and residual astigmatism with Paraperm O2 and Boston II lenses on toric corneas. | 1987 | Am J Optom Physiol Opt | pmid:3591898 |
Newsholme P et al. | Rates of utilization and fates of glucose, glutamine, pyruvate, fatty acids and ketone bodies by mouse macrophages. | 1987 | Biochem. J. | pmid:3593269 |
Fujiwara Y et al. | Heritable disorders of DNA repair: xeroderma pigmentosum and Fanconi's anemia. | 1987 | Curr. Probl. Dermatol. | pmid:3595188 |
Su WJ et al. | Role of volatile fatty acids in colonization resistance to Clostridium difficile in gnotobiotic mice. | 1987 | Infect. Immun. | pmid:3596806 |
Ceccarelli P et al. | Resistance to thyroid hormone diagnosed by the reduced response of fibroblasts to the triiodothyronine-induced suppression of fibronectin synthesis. | 1987 | J. Clin. Endocrinol. Metab. | pmid:3597704 |
Krastev A et al. | Changes in brain haemodynamics induced by light-chain fatty acids. | 1987 | Folia Med (Plovdiv) | pmid:3144504 |
Costa EM and Feldman D | Modulation of 1,25-dihydroxyvitamin D3 receptor binding and action by sodium butyrate in cultured pig kidney cells (LLC-PK1). | 1987 | J. Bone Miner. Res. | pmid:2843001 |
Nagasawa T et al. | Nitrile hydratase of Pseudomonas chlororaphis B23. Purification and characterization. | 1987 | Eur. J. Biochem. | pmid:3830164 |
Edwards AM et al. | Modulation of gamma-glutamyltranspeptidase in normal rat hepatocytes in culture by cell density, epidermal growth factor and agents which alter cell differentiation. | 1987 | Carcinogenesis | pmid:2890444 |
Wasserman L et al. | Differential effects of sodium butyrate and dimethylsulfoxide on gamma-glutamyl transpeptidase and alkaline phosphatase activities in MCF-7 breast cancer cells. | 1987 | Exp. Cell Biol. | pmid:2890541 |
Fraser JK and Berridge MV | Induction of B-lymphocyte antigens on the chronic myeloid leukemic cell line K562 using sodium butyrate. | 1987 | Exp. Hematol. | pmid:2952519 |
Braun PC et al. | Effect of cerulenin and sodium butyrate on chitin synthesis in Candida albicans. | 1987 | Can. J. Microbiol. | pmid:2957042 |
Malik H et al. | Chemical inducers of differentiation, dimethylsulfoxide, butyric acid, and dimethylthiourea, induce selective ultrastructural patterns in B16 melanoma cells. | 1987 | Biol. Cell | pmid:2960403 |
Janati-Idrissi R et al. | [Selection of mutants of Clostridium acetobutylicum defective in production of acetone]. | 1987 May-Jun | Ann. Inst. Pasteur Microbiol. | pmid:3620201 |
Edsbäcker S et al. | Metabolic acetal splitting of budesonide. A novel inactivation pathway for topical glucocorticoids. | 1987 May-Jun | Drug Metab. Dispos. | pmid:2886320 |
Galenko-IaroshevckiÄ PA et al. | [Complex formation of lithium hydroxybutyrate with ions of Na+, K+, Ba2+, Mg2+, and Ca2+]. | 1987 Nov-Dec | Farmakol Toksikol | pmid:3436425 |
Bergeret M et al. | Immunomodulatory effects of arginine butyrate. | 1987 Oct-Dec | J. Biol. Regul. Homeost. Agents | pmid:3140599 |
Hamasaki Y et al. | Butyric acid enhances cyclooxygenase activity in rat basophilic leukemia 2H3 cells. | 1988 | Nippon Ketsueki Gakkai Zasshi | pmid:3144111 |
Kan YY et al. | Effects of polar organic compounds on gynecologic cancers. | 1988 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:3224317 |
Clouet PM and Bourre JM | Ketone body utilization for lipid synthesis in the murine sciatic nerve: alterations in the dysmyelinating trembler mutant. | 1988 | J. Neurochem. | pmid:3361304 |
Salam S | Inhibitor(S) of prostaglandin endoperoxide synthase and lipoxygenase activity in extracts of barley. | 1988 | Pak J Pharm Sci | pmid:16414615 |
Staecker JL et al. | Sodium butyrate preserves aspects of the differentiated phenotype of normal adult rat hepatocytes in culture. | 1988 | J. Cell. Physiol. | pmid:2899578 |
Almlöf I et al. | Induction of basophilic differentiation in the human basophilic cell line KU812. | 1988 | Scand. J. Immunol. | pmid:2973655 |
Zhu XZ and Chuang DM | Differential regulation by butyrate and dibutyryl cyclic AMP of delta-opioid, alpha 2-adrenergic, and muscarinic cholinergic receptors in NCB-20 cells. | 1988 | J. Neurochem. | pmid:2826684 |
Rossi JF et al. | Phenotypic and functional analysis of 1,25-dihydroxyvitamin D3 receptor mediated modulation of the human myeloma cell line RPMI 8226. | 1988 | Cancer Res. | pmid:2830017 |
Takeyasu K et al. | Ouabain-sensitive (Na+ + K+)-ATPase activity expressed in mouse L cells by transfection with DNA encoding the alpha-subunit of an avian sodium pump. | 1988 | J. Biol. Chem. | pmid:2831227 |
Sorimachi K | Induction of alkaline phosphatase activity by synergistic action of dibutyryl cyclic adenosine monophosphate, prednisolone, butyrate and sodium chloride in cultured cells. | 1988 | Cell Biochem. Funct. | pmid:2832093 |
Sack TL et al. | Cyclic-AMP-stimulated synthesis and release of carcinoembryonic antigen by pancreatic cancer cells. | 1988 | Int. J. Pancreatol. | pmid:2834472 |
Ladoux A et al. | An increase in intracellular pH is a general response of promonocytic cells to differentiating agents. | 1988 | FEBS Lett. | pmid:2455658 |
Pennypacker KR et al. | Calmodulin-binding proteins in human Y-79 retinoblastoma and HTB-14 glioma cell lines. | 1988 | J. Neurochem. | pmid:2834519 |
Kassis S et al. | Modulation of the beta-adrenergic receptor-coupled adenylate cyclase by chemical inducers of differentiation: effects on beta receptors and the inhibitory regulatory protein Gi. | 1988 | J. Recept. Res. | pmid:2455808 |
Germain L et al. | Biliary epithelial and hepatocytic cell lineage relationships in embryonic rat liver as determined by the differential expression of cytokeratins, alpha-fetoprotein, albumin, and cell surface-exposed components. | 1988 | Cancer Res. | pmid:2457432 |
Gross JL et al. | Plasminogen activator and inhibitor activity in human glioma cells and modulation by sodium butyrate. | 1988 | Cancer Res. | pmid:3121170 |
Nishimura J et al. | Regulation of biosynthesis and phosphorylation of P210bcr/abl protein during differentiation induction of K 562 cells. | 1988 | Leuk. Res. | pmid:2464113 |
Baskova IP et al. | Thrombolytic agents of the preparation from the medicinal leeches. | 1988 | Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. | pmid:2459014 |
Inhorn L et al. | Restoration of adenylate cyclase responsiveness in murine myeloid leukemia permits inhibition of proliferation by hormone. Butyrate augments catalytic activity of adenylate cyclase. | 1988 | Blood | pmid:3128344 |
Asher C and Garty H | Aldosterone increases the apical Na+ permeability of toad bladder by two different mechanisms. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3140240 |
Spotti D et al. | Intermediary metabolism and glycemic control in insulin-dependent diabetic uremic patients treated by continuous peritoneal dialysis. | 1988 | Nephron | pmid:3041295 |
Fischkoff SA | Graded increase in probability of eosinophilic differentiation of HL-60 promyelocytic leukemia cells induced by culture under alkaline conditions. | 1988 | Leuk. Res. | pmid:3184985 |
Takano M et al. | Sodium butyrate increases glucose transporter expression in LLC-PK1 cells. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3186708 |
Januszewicz E et al. | Butyric acid: inhibition of non-leukemic and chronic myeloid leukemia granulocyte macrophage clonal growth. | 1988 | Med Oncol Tumor Pharmacother | pmid:3193830 |
Rhoads DB et al. | Evidence for expression of the facilitated glucose transporter in rat hepatocytes. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3194405 |
Brass EP and Beyerinck RA | Effects of propionate and carnitine on the hepatic oxidation of short- and medium-chain-length fatty acids. | 1988 | Biochem. J. | pmid:3134008 |
Schönfeld P et al. | On the mechanism of the so-called uncoupling effect of medium- and short-chain fatty acids. | 1988 | Biochim. Biophys. Acta | pmid:3196710 |
Graham KA and Buick RN | Sodium butyrate induces differentiation in breast cancer cell lines expressing the estrogen receptor. | 1988 | J. Cell. Physiol. | pmid:3294239 |
Durix A and Jean-Blain C | [Influence of fasting and the dietary lipid content on ketogenesis in isolated rabbit hepatocytes]. | 1988 | Reprod Nutr Dev | pmid:3254599 |
Nakagawa T et al. | Transcriptional and posttranscriptional modulation of calcitonin gene expression by sodium n-butyrate in cultured human medullary thyroid carcinoma. | 1988 | Cancer Res. | pmid:3258183 |
Filippovich IV et al. | Effect of the inducers of cellular differentiation and of ionizing radiation on thymus lymphocytes: chromatin degradation and programmed cell death. | 1988 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:3258296 |
Gladhaug IP et al. | Effects of butyrate on epidermal growth factor receptor binding, morphology, and DNA synthesis in cultured rat hepatocytes. | 1988 | Cancer Res. | pmid:3263190 |
Chatham J et al. | Inhibition of glucose phosphorylation by fatty acids in the perfused rat heart. | 1988 | FEBS Lett. | pmid:3169268 |
Albertini S et al. | The in vitro porcine brain tubulin assembly assay: effects of a genotoxic carcinogen (aflatoxin B1), eight tumor promoters and nine miscellaneous substances. | 1988 | Mutat. Res. | pmid:3173378 |
Gressner AM and Haarmann R | Effect of n-butyrate on the synthesis of sulfated glycosaminoglycans and hyaluronate by rat liver fat-storing cells (Ito cells). | 1988 | Biochem. Pharmacol. | pmid:3178890 |
Vernia P et al. | Organic anions and the diarrhea of inflammatory bowel disease. | 1988 | Dig. Dis. Sci. | pmid:3180970 |
Leith JT | Potentiation of X ray sensitivity by combinations of sodium butyrate and buthionine sulfoximine. | 1988 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:3182335 |
Chang CC et al. | Effects of sodium butyrate on the secretion of beta-2-microglobulin and calcitonin in a human ovarian cancer cell line OC-3-VGH. | 1988 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:3066455 |
Campbell M and Chader GJ | Retinoblastoma cells in tissue culture. | 1988 | Ophthalmic Paediatr Genet | pmid:3068600 |
Ohwaki K | [High carboxylic acid level in the gingival crevicular fluid (GCF) of the patients with advanced periodontal disease]. | 1988 | Nihon Shishubyo Gakkai Kaishi | pmid:3078007 |
Herold KM and Rothberg PG | Evidence for a labile intermediate in the butyrate induced reduction of the level of c-myc RNA in SW837 rectal carcinoma cells. | 1988 | Oncogene | pmid:3078950 |
Hellweg R et al. | Nerve growth factor synthesis in cultured rat iris: modulation by endogenous transmitter substances. | 1988 | Exp. Cell Res. | pmid:2844567 |
Hidal JT and Kaplan MM | Inhibition of thyroxine 5'-deiodination type II in cultured human placental cells by cortisol, insulin, 3', 5'-cyclic adenosine monophosphate, and butyrate. | 1988 | Metab. Clin. Exp. | pmid:2838733 |
Laeng H et al. | Participation of mitochondrial proliferation in morphological differentiation of murine mastocytoma cells. | 1988 | Exp. Cell Res. | pmid:2844569 |
Courtin F et al. | Induction of type II 5'-deiodinase activity by cyclic adenosine 3', 5'-monophosphate in cultured rat astroglial cells. | 1988 | Endocrinology | pmid:2841100 |
Ryan MP and Higgins PJ | Cytoarchitecture of Kirsten sarcoma virus-transformed rat kidney fibroblasts: butyrate-induced reorganization within the actin microfilament network. | 1988 | J. Cell. Physiol. | pmid:2844835 |
Langdon SP et al. | Effect of sodium butyrate and other differentiation inducers on poorly differentiated human ovarian adenocarcinoma cell lines. | 1988 | Cancer Res. | pmid:3167862 |
Kisauzi DN and Leek BF | Liver blood flow and volatile fatty acid utilization in sheep before and after carbon tetrachloride treatment. | 1988 | J. Comp. Pathol. | pmid:3417915 |
Bidet M et al. | Role of monocarboxylic acid transport in intracellular pH regulation of isolated proximal cells. | 1988 | Biochim. Biophys. Acta | pmid:3342236 |
Davidson AM and Halestrap AP | Inorganic pyrophosphate is located primarily in the mitochondria of the hepatocyte and increases in parallel with the decrease in light-scattering induced by gluconeogenic hormones, butyrate and ionophore A23187. | 1988 | Biochem. J. | pmid:2845949 |
Yusta B et al. | Comparison of the effects of forskolin and dibutyryl cyclic AMP in neuroblastoma cells: evidence that some of the actions of dibutyryl cyclic AMP are mediated by butyrate. | 1988 | J. Neurochem. | pmid:2846786 |
Yokochi T et al. | Effect of activation of the Epstein-Barr virus genome on expression of B cell differentiation antigens of Burkitt's lymphoma lines. | 1988 | Microbiol. Immunol. | pmid:2850450 |
Morise T et al. | Biological activity of partially purified digitalis-like substance and Na-K-ATPase inhibitor in rats. | 1988 | Jpn. Circ. J. | pmid:2852264 |
Ortiz-Caro J et al. | Short chain fatty acids modulate nuclear receptor and extranuclear L-triiodothyronine levels in glial C6 cells by different mechanisms. | 1988 | Endocrinology | pmid:2836168 |
Li JS and Cheng YC | Interaction of Epstein-Barr virus DNA polymerase with aphidicolin, phosphonoformate and 5'-GMP. | 1988 | Virus Genes | pmid:2852412 |
Prasad S and Thakur MK | Age-dependent effects of sodium butyrate and hydrocortisone on acetylation of high mobility group proteins of rat liver. | 1988 | Biochem. Int. | pmid:3365268 |
Niles RM et al. | The effect of sodium butyrate and retinoic acid on growth and CEA production in a series of human colorectal tumor cell lines representing different states of differentiation. | 1988 | Cancer Invest. | pmid:3365571 |
Leith JT | Modification of the hypoxic fraction of a xenografted human colon tumor by differentiation-inducing agents. | 1988 | J. Natl. Cancer Inst. | pmid:3367384 |
Cattini PA et al. | Effect of butyrate on thyroid hormone-mediated gene expression in rat pituitary tumour cells. | 1988 | Mol. Cell. Endocrinol. | pmid:3371552 |
Leith JT et al. | Changes in X-ray sensitivity and glutathione content of human colon tumor cells after exposure to the differentiation-inducing agent sodium butyrate. | 1988 | Radiat. Res. | pmid:3375444 |
Joshi SS et al. | Effects of differentiation inducing chemicals on in vivo malignancy and NK susceptibility of metastatic lymphoma cells. | 1988 | Cancer Detect. Prev. | pmid:3390859 |
Kamech N and Seif R | Evidence for new cellular proteins which may negatively control DNA replication or cell growth in rat 3T3 fibroblasts. | 1988 | Exp. Cell Res. | pmid:3391246 |
Reading CL et al. | Analysis of cell surface glycoprotein changes related to hematopoietic differentiation. | 1988 | J. Cell. Biochem. | pmid:3392108 |
Tatsuka M et al. | An improved method of electroporation for introducing biologically active foreign genes into cultured mammalian cells. | 1988 | Exp. Cell Res. | pmid:3409976 |
Drucker DJ et al. | Proglucagon gene expression and posttranslational processing in a hamster islet cell line. | 1988 | Endocrinology | pmid:3416818 |
Szabad J et al. | The effects of two mutations connected with chromatin functions on female germ-line cells of Drosophila. | 1988 | Mol. Gen. Genet. | pmid:3422705 |
Giancotti V et al. | Butyrate effect on nuclear proteins of two Chinese hamster cell lines. | 1988 | Exp. Cell Res. | pmid:3335229 |
Zhang DE and Nelson DA | Histone acetylation in chicken erythrocytes. Rates of deacetylation in immature and mature red blood cells. | 1988 | Biochem. J. | pmid:3355515 |
Virtanen I et al. | Expression of intermediate filaments and synaptophysin show neuronal properties and lack of glial characteristics in Y79 retinoblastoma cells. | 1988 | Lab. Invest. | pmid:3141718 |