butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Ebert SN et al. | Adrenergic differentiation potential in PC12 cells: influence of sodium butyrate and dexamethasone. | 1997 | Brain Res. Mol. Brain Res. | pmid:9221898 |
Alaoui-Ismaïli O et al. | Odor hedonics: connection with emotional response estimated by autonomic parameters. | 1997 | Chem. Senses | pmid:9218136 |
McBain JA et al. | Apoptotic death in adenocarcinoma cell lines induced by butyrate and other histone deacetylase inhibitors. | 1997 | Biochem. Pharmacol. | pmid:9214697 |
Singh B et al. | Butyrate can act as a stimulator of growth or inducer of apoptosis in human colonic epithelial cell lines depending on the presence of alternative energy sources. | 1997 | Carcinogenesis | pmid:9214612 |
Nakajima T et al. | The effect of carnitine on ketogenesis in perfused livers from juvenile visceral steatosis mice with systemic carnitine deficiency. | 1997 | Pediatr. Res. | pmid:9212045 |
Gossett RE et al. | Expression of fatty acyl-CoA binding proteins in colon cells: response to butyrate and transformation. | 1997 | Lipids | pmid:9208385 |
Marchetti MC et al. | Possible mechanisms involved in apoptosis of colon tumor cell lines induced by deoxycholic acid, short-chain fatty acids, and their mixtures. | 1997 | Nutr Cancer | pmid:9200153 |
Edward M et al. | Effect of retinoic acid on melanoma cell-derived factor stimulation of fibroblast glycosaminoglycan synthesis. | 1997 | Melanoma Res. | pmid:9195557 |
Otonkoski T et al. | Nicotinamide and sodium butyrate for the induction of fetal porcine beta-cell differentiation prior to transplantation. | 1997 | Transplant. Proc. | pmid:9193518 |
Wallace KK et al. | In vivo and in vitro effects of thiolactomycin on fatty acid biosynthesis in Streptomyces collinus. | 1997 | J. Bacteriol. | pmid:9190803 |
Graham ME et al. | Modification of annexin II expression in PC12 cell lines does not affect Ca(2+)-dependent exocytosis. | 1997 | Mol. Biol. Cell | pmid:9188096 |
Kashanchi F et al. | Rapid and sensitive detection of cell-associated HIV-1 in latently infected cell lines and in patient cells using sodium-n-butyrate induction and RT-PCR. | 1997 | J. Med. Virol. | pmid:9179766 |
Ou HC et al. | Sodium butyrate decreases histamine-stimulated calcium mobilization in C6 glioma cells. | 1997 | Neuroreport | pmid:9172138 |
Dimitrov SI and Wolffe AP | Fine resolution of histones by two-dimensional polyacrylamide gel electrophoresis: developmental implications. | 1997 | Methods | pmid:9169195 |
Russo GL et al. | Down-regulation of protein kinase CKII activity by sodium butyrate. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9168912 |
Napolitano LM | Dose-response effect of butyrate. | 1997 May-Jun | JPEN J Parenter Enteral Nutr | pmid:9168372 |
Kim J et al. | Studies on the effects of selenium on rumen microbial fermentation in vitro. | 1997 | Biol Trace Elem Res | pmid:9164665 |
Chen WY et al. | Reactivation of silenced, virally transduced genes by inhibitors of histone deacetylase. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9159154 |
Garcia-Villalba P et al. | Histone acetylation influences thyroid hormone and retinoic acid-mediated gene expression. | 1997 | DNA Cell Biol. | pmid:9150429 |
Scheppach W et al. | Effects of short-chain fatty acids on the inflamed colonic mucosa. | 1997 | Scand. J. Gastroenterol. Suppl. | pmid:9145448 |
Benard O and Balasubramanian KA | Modulation of glutathione level during butyrate-induced differentiation in human colon derived HT-29 cells. | 1997 | Mol. Cell. Biochem. | pmid:9144324 |
Mariadason JM et al. | Effect of short-chain fatty acids on paracellular permeability in Caco-2 intestinal epithelium model. | 1997 | Am. J. Physiol. | pmid:9142899 |
Pöllänen MT et al. | Bacterial metabolites sodium butyrate and propionate inhibit epithelial cell growth in vitro. | 1997 | J. Periodont. Res. | pmid:9138199 |
Autrup H et al. | Effect of various chemicals on the metabolism of benzo(a)pyrene by cultured rat colon. | 1977 | Chem. Biol. Interact. | pmid:912816 |
Siavoshian S et al. | Butyrate stimulates cyclin D and p21 and inhibits cyclin-dependent kinase 2 expression in HT-29 colonic epithelial cells. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9125124 |
Zimra Y et al. | Butyric acid and pivaloyloxymethyl butyrate, AN-9, a novel butyric acid derivative, induce apoptosis in HL-60 cells. | 1997 | J. Cancer Res. Clin. Oncol. | pmid:9119880 |
Jasinskas A et al. | Turnover of histone acetyl groups during sea urchin early development is not required for histone, heat shock and actin gene transcription. | 1997 | Biochim. Biophys. Acta | pmid:9116030 |
Wang MC et al. | Protein tyrosine phosphatase-dependent activation of beta-globin and delta-aminolevulinic acid synthase genes in the camptothecin-induced IW32 erythroleukemia cell differentiation. | 1997 | Mol. Pharmacol. | pmid:9106619 |
Marchetti C et al. | Deoxycholic acid and SCFA-induced apoptosis in the human tumor cell-line HT-29 and possible mechanisms. | 1997 | Cancer Lett. | pmid:9103263 |
Bingham S | Meat, starch and non-starch polysaccharides, are epidemiological and experimental findings consistent with acquired genetic alterations in sporadic colorectal cancer? | 1997 | Cancer Lett. | pmid:9103247 |
Rolandelli RH et al. | Intravenous butyrate and healing of colonic anastomoses in the rat. | 1997 | Dis. Colon Rectum | pmid:9102264 |
Böhm L et al. | Influence of histone acetylation on the modification of cytoplasmic and nuclear proteins by ADP-ribosylation in response to free radicals. | 1997 | Biochim. Biophys. Acta | pmid:9101708 |
Zoran DL et al. | Diet and carcinogen alter luminal butyrate concentration and intracellular pH in isolated rat colonocytes. | 1997 | Nutr Cancer | pmid:9101550 |
Niki S et al. | [A case of hepatocellular carcinoma associated with autoimmune hepatitis and increased scintigraphy of liver accumulation]. | 1997 | Nihon Shokakibyo Gakkai Zasshi | pmid:9095644 |
Moulding D et al. | Regulation of neutrophil apoptosis by sodium butyrate. | 1996 | Biologicals | pmid:9088543 |
Litchfield TM and Sauer GR | Metallothionein induction in calcifying growth plate cartilage chondrocytes. | 1996 | Connect. Tissue Res. | pmid:9084657 |
Sun SH et al. | Altered phospholipid metabolism in sodium butyrate-induced differentiation of C6 glioma cells. | 1997 | Lipids | pmid:9076664 |
Skretting G et al. | Sodium butyrate inhibits the expression of the human lecithin: cholesterol acyltransferase gene in HepG2 cells by a post-transcriptional mechanism. | 1997 | FEBS Lett. | pmid:9074647 |
Stein TP et al. | Weight loss, the gut and the inflammatory response in aids patients. | 1997 | Cytokine | pmid:9071566 |
Huang N et al. | Inhibition of IL-8 gene expression in Caco-2 cells by compounds which induce histone hyperacetylation. | 1997 | Cytokine | pmid:9067093 |
Scheppach W et al. | Histological changes in the colonic mucosa following irrigation with short-chain fatty acids. | 1997 | Eur J Gastroenterol Hepatol | pmid:9058627 |
Bordonaro M and Augenlicht L | The 3' untranslated region of the carcinoembryonic antigen gene plays a minimal role in the regulation of gene expression. | 1997 | Cell Growth Differ. | pmid:9056678 |
Niitsu N et al. | AML1a but not AML1b inhibits erythroid differentiation induced by sodium butyrate and enhances the megakaryocytic differentiation of K562 leukemia cells. | 1997 | Cell Growth Differ. | pmid:9056674 |
Mandal M et al. | Bcl-2 deregulation leads to inhibition of sodium butyrate-induced apoptosis in human colorectal carcinoma cells. | 1997 | Carcinogenesis | pmid:9054611 |
Chapman MA et al. | Metabolic adaptation of terminal ileal mucosa after construction of an ileoanal pouch. | 1997 | Br J Surg | pmid:9043459 |
Niederman R et al. | Short-chain carboxylic acid concentration in human gingival crevicular fluid. | 1997 | J. Dent. Res. | pmid:9042080 |
Hague A et al. | Butyrate acts as a survival factor for colonic epithelial cells: further fuel for the in vivo versus in vitro debate. | 1997 | Gastroenterology | pmid:9041270 |
Hass R et al. | Lack of butyrate is associated with induction of Bax and subsequent apoptosis in the proximal colon of guinea pig. | 1997 | Gastroenterology | pmid:9041249 |
Aukema HM et al. | Butyrate alters activity of specific cAMP-receptor proteins in a transgenic mouse colonic cell line. | 1997 | J. Nutr. | pmid:9040538 |
Rogler LE | Selective bipotential differentiation of mouse embryonic hepatoblasts in vitro. | 1997 | Am. J. Pathol. | pmid:9033273 |