butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Lupton JR | Butyrate and colonic cytokinetics: differences between in vitro and in vivo studies. | 1995 | Eur. J. Cancer Prev. | pmid:7496326 |
Johnson IT | Butyrate and markers of neoplastic change in the colon. | 1995 | Eur. J. Cancer Prev. | pmid:7496325 |
Hague A and Paraskeva C | The short-chain fatty acid butyrate induces apoptosis in colorectal tumour cell lines. | 1995 | Eur. J. Cancer Prev. | pmid:7496324 |
Li M et al. | Expression and regulation of glycosyltransferases for N-glycosyl oligosaccharides in fresh human surgical and murine tissues and cultured cell lines. | 1995 | Clin. Sci. | pmid:7493440 |
Parratt JR et al. | Functional effects of intracellular pH alteration in the human uterus: simultaneous measurements of pH and force. | 1995 | J. Reprod. Fertil. | pmid:7490717 |
Ranganna K et al. | Sodium butyrate inhibits platelet-derived growth factor-induced proliferation of vascular smooth muscle cells. | 1995 | Arterioscler. Thromb. Vasc. Biol. | pmid:7489253 |
Berwald-Netter Y et al. | Phenotypic modulation in mouse neuroblastoma cells: the case of acetylcholinesterase. | 1978 | Natl Cancer Inst Monogr | pmid:748757 |
Klijn N et al. | Identification of Clostridium tyrobutyricum as the causative agent of late blowing in cheese by species-specific PCR amplification. | 1995 | Appl. Environ. Microbiol. | pmid:7487024 |
Awad AB et al. | Prostaglandin synthesis in human cancer cells: influence of fatty acids and butyrate. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7480078 |
Ferré P et al. | The development of ketogenesis at birth in the rat. | 1978 | Biochem. J. | pmid:747651 |
Jalouzot R and Toublan B | Multiple effects of 5 mM sodium butyrate on Physarum polycephalum macroplasmodia. | 1981 | Cell Tissue Res. | pmid:7471173 |
Kitzis A et al. | Localization of phosphoproteins and of protein kinases in chromatin from butyrate treated HTC cells. | 1980 | Biochem. Biophys. Res. Commun. | pmid:7470113 |
Porteous JW | Glutamate, glutamine, aspartate, asparagine, glucose and ketone-body metabolism in chick intestinal brush-border cells. | 1980 | Biochem. J. | pmid:7470024 |
Lemcke RM and Burrows MR | A comparative study of spirochaetes from the porcine alimentary tract. | 1981 | J Hyg (Lond) | pmid:7462601 |
Roediger WE and Moore A | Effect of short-chaim fatty acid on sodium absorption in isolated human colon perfused through the vascular bed. | 1981 | Dig. Dis. Sci. | pmid:7460712 |
Dexter DL et al. | N,N-dimethylformamide and sodium butyrate modulation of the activities of purine-metabolizing enzymes in cultured human colon carcinoma cells. | 1981 | Cancer Res. | pmid:7459868 |
Sawicki J et al. | Benzo(a)pyrene metabolism and metabolites binding to DNA in the presence of BHA. | 1980 | Arch. Geschwulstforsch. | pmid:7458578 |
Daniell E | Cells inhibited by n-butyrate support adenovirus replication. | 1980 | Virology | pmid:7456334 |
Tamura J et al. | [Studies on toxicity of clobetasone-17-butyrate (II)--chronic toxicity in rats (author's transl)]. | 1980 | J Toxicol Sci | pmid:7452742 |
Bode J et al. | Modulation of the nucleosome structure by histone acetylation. | 1980 | Eur. J. Biochem. | pmid:7439155 |
Roediger WE | Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man. | 1980 | Gut | pmid:7429343 |
Fiol de Cuneo M et al. | Alterations induced by alloxan-diabetes and starvation on functional activity of the rat portal vein perfused in vitro. | 1980 | Can. J. Physiol. Pharmacol. | pmid:7427791 |
Cremer-Lacuara MG et al. | Substrate supply and function of isolated venous smooth muscle under anoxia and metabolic inhibition. | 1980 | Can. J. Physiol. Pharmacol. | pmid:7427790 |
Milhaud P et al. | Sodium butyrate affects expression of fibronectin on CHO cells: specific increase in antibody-complement-mediated cytotoxicity. | 1980 | J. Cell. Physiol. | pmid:7410488 |
Covault J and Chalkley R | The identification of distinct populations of acetylated histone. | 1980 | J. Biol. Chem. | pmid:7410415 |
D'Anna JA et al. | Concentration-dependent effects of sodium butyrate in Chinese hamster cells: cell-cycle progression, inner-histone acetylation, histone H1 dephosphorylation, and induction of an H1-like protein. | 1980 | Biochemistry | pmid:7397096 |
Kaplan BA and Trimber CJ | Corneal response to extended wear of CAB contact lenses in aphakia. | 1980 | Ophthalmology | pmid:7393534 |
Kitzis A et al. | Effect of sodium butyrate on chromatin structure. | 1980 | Biochem. Biophys. Res. Commun. | pmid:7387680 |
Hayman EG et al. | Butyrate restores fibronectin at cell surface of transformed cells. | 1980 | Exp. Cell Res. | pmid:7379876 |
Williamson DH et al. | Interactions between vasopressin and glucagon on ketogenesis and oleate metabolism in isolated hepatocytes from fed rats. | 1980 | Biochem. J. | pmid:7378069 |
Silva P et al. | Competition between sodium reabsorption and gluconeogenesis in kidneys of steroid-treated rats. | 1980 | Am. J. Physiol. | pmid:7377301 |
Marshall MO and Knudsen J | Factors influencing the in vitro activity of diacylglycerol acyltransferase from bovine mammary gland and liver towards butyryl-CoA and palmitoyl-CoA. | 1980 | Biochim. Biophys. Acta | pmid:7370285 |
Hansen JK and Knudsen J | Transacylation as a chain-termination mechanism in fatty acid synthesis by mammalian fatty acid synthetase. Synthesis of butyrate and hexanoate by lactating cow mammary gland fatty acid synthetase. | 1980 | Biochem. J. | pmid:7370014 |
Galzigna L et al. | Properties of two derivatives of gamma-aminobutyric acid (GABA) capable of abolishing Cardiazol- and bicuculline-induced convulsions in the rat. | 1978 | Arch Int Pharmacodyn Ther | pmid:736693 |
Ulasevich EIu et al. | [Effect of sutan on the soil microflora in corn plantings]. | 1980 Jan-Feb | Mikrobiol. Zh. | pmid:7366483 |
van Gylswyk NO | Fusobacterium polysaccharolyticum sp.nov., a gram-negative rod from the rumen that produces butyrate and ferments cellulose and starch. | 1980 | J. Gen. Microbiol. | pmid:7365452 |
Fiszman MY et al. | Expression of myogenic differentiation and myotube formation by chick embryo myoblasts in the presence of sodium butyrate. | 1980 | Exp. Cell Res. | pmid:7358093 |
Kim YS et al. | Effects of sodium butyrate and dimethylsulfoxide on biochemical properties of human colon cancer cells. | 1980 | Cancer | pmid:7357511 |
Laundon CH et al. | The characterization of hCG regulation in cultured human amniotic fluid cells. | 1981 | Prenat. Diagn. | pmid:7346828 |
Kottel RH and Fishman WH | Placental alkaline phosphatase isoenzyme expression by the non-HeLa DoT cervical-carcinoma cell line. | 1981 | Biochem. J. | pmid:7342975 |
Metcalf EC et al. | The effect of ligand presaturation on the interaction of serum albumins with an immobilized Cibacron Blue 3G-A studied by affinity gel electrophoresis. | 1981 | Biochem. J. | pmid:7340816 |
Xue S and Rao PN | Sodium butyrate blocks HeLa cells preferentially in early G1 phase of the cell cycle. | 1981 | J. Cell. Sci. | pmid:7320081 |
Hradilek A et al. | The role of heme in the regulation of iron uptake during Friend cell differentiation. | 1981 | Acta Biol. Med. Ger. | pmid:7315097 |
Aozasa K et al. | Malignant lymphoma in the nose. Clinicopathological differences from the malignant histiocytosis presenting as lethal midline granuloma. | 1981 | Pathol. Res. Pract. | pmid:7312704 |
Brotherton TW et al. | Only a small fraction of avian erythrocyte histone is involved in ongoing acetylation. | 1981 | Nucleic Acids Res. | pmid:7312625 |
Clark EA et al. | Induction of target antigens and conversion to susceptible phenotype of NK-cell-resistant lymphoid cell line. | 1981 | Int. J. Cancer | pmid:7309297 |
Suzuki E et al. | Metabolic fate and carcinogenicity of N-(omega-hydroxyalkyl) N-(4-hydroxybutyl) nitrosamines analogs of N-butyl-N-(4-hydroxy-butyl) nitrosamine, in the rat. | 1981 | Gan | pmid:7308665 |
Darzynkiewicz Z et al. | Effect of n-butyrate on cell cycle progression and in situ chromatin structure of L1210 cells. | 1981 | Exp. Cell Res. | pmid:7308309 |
Schröter H et al. | The extent of histone acetylation induced by butyrate and the turnover of acetyl groups depend on the nature of the cell line. | 1981 | Eur. J. Biochem. | pmid:7308217 |
Herz F et al. | Alkaline phosphatase in HT-29, a human colon cancer cell line: influence of sodium butyrate and hyperosmolality. | 1981 | Arch. Biochem. Biophys. | pmid:7305346 |
Cox GS | Synthesis of the glycoprotein hormone alpha subunit and placental alkaline phosphatase by HeLa cells: effect of tunicamycin, 2-deoxyglucose, and sodium butyrate. | 1981 | Biochemistry | pmid:7295657 |
Fallon RJ and Cox RP | Relation of cell cycle position and chromatin decondensation to ectopic hormone synthesis in HeLa cells. | 1981 | Somatic Cell Genet. | pmid:7292249 |
D'Anna JA et al. | Histones H1(o)a and H1(o)b are the same as CHO histones H1(III) and H1(IV): new features of H1(o) phosphorylation during the cell cycle. | 1981 | Biochemistry | pmid:7284339 |
Widdel F and Pfennig N | Sporulation and further nutritional characteristics of Desulfotomaculum acetoxidans. | 1981 | Arch. Microbiol. | pmid:7283637 |
Vinores SA et al. | Increased levels of neuron-specific enolase in PC12 pheochromocytoma cells as a result of nerve growth factor treatment. | 1981 | J. Neurochem. | pmid:7276941 |
Palmiter RD et al. | Steroid hormone regulation of ovalbumin and conalbumin gene transcription. A model based upon multiple regulatory sites and intermediary proteins. | 1981 | J. Biol. Chem. | pmid:7263632 |
Knudsen J et al. | Quantitative extraction and separation from [1-14C]acetate and preparation for ratio gas chromatography of microgram amounts of a 14C-labeled mixture of butyrate and longer-chain-length fatty acids. | 1981 | Anal. Biochem. | pmid:7258625 |
Madhosingh C and Orr W | Sterol ester hydrolase in Fusarium oxysporum. | 1981 | Lipids | pmid:7242270 |
Heifetz A and Prager MD | The effect of butyrate on sulfated glycoprotein biosynthesis by human kidney tumor cells. | 1981 | J. Biol. Chem. | pmid:7240225 |
Gómez-Lira MM and Bode J | Effects of butyrate upon the metaphase-specific deacetylation of histone H4. | 1981 | FEBS Lett. | pmid:7238883 |
Voigt J et al. | Absence of hydrocortisone from cytoplasmic hormone-protein complexes formed in vivo after administration of biologically active doses of [3H]hydrocortisone. | 1981 | Biochim. Biophys. Acta | pmid:7236733 |
Shons AR et al. | A rigid transparent face mask for control of scar hypertrophy. | 1981 | Ann Plast Surg | pmid:7235550 |
Hecht SS et al. | Metabolism of the tobacco specific nitrosamines, N'-nitrosonornicotine and 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone. | 1980 | IARC Sci. Publ. | pmid:7228296 |
Serrentino R and Gervasi PG | [Photometric determination of microsomal epoxide hydrase activity by the 4-(p-nitrobenzyl)pyridine test]. | 1980 | Boll. Soc. Ital. Biol. Sper. | pmid:7225249 |
Sakata T and Tamate H | Rumen epithelial cell proliferation accelerated by rapid increase in intraruminal butyrate. | 1978 | J. Dairy Sci. | pmid:721981 |
Moyer ED et al. | Multiple systems organ failure: III Contrasts in plasma amino acid profiles in septic trauma patients who subsequently survive and do not survive-effects of intravenous amino acids. | 1981 | J Trauma | pmid:7218392 |
Dexter DL et al. | Induction by butyrate of differentiated properties in cloned murine rhabdomyosarcoma cells. | 1981 | Differentiation | pmid:7215726 |
Chou JY | Regulation of the synthesis of human chorionic gonadotropin by strains of HeLa cells in culture. | 1978 | In Vitro | pmid:721101 |
Horwitz KB et al. | Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance. | 1982 | Cell | pmid:7200400 |
Uto N | Exocytosis of cortical granules and formation of microvilli in sea urchin eggs insufficiently activated by butyric acid and benzimidazole. | 1981 | Acta Embryol Morphol Exp | pmid:7198857 |
Kinoshita F et al. | Sodium butyrate stimulates hCG and hCG-alpha production in a human choriocarcinoma cell line (BeWo). | 1981 | J. Cancer Res. Clin. Oncol. | pmid:7196916 |
Narasimhalu PR et al. | Adaptation of lactating cows to rations containing urea. | 1980 | J. Dairy Sci. | pmid:7191435 |
Guillouzo A et al. | Early reversible nuclear alterations induced by sodium butyrate in cultured hepatoma cells. | 1980 | Cell Biol. Int. Rep. | pmid:7191351 |
Ullrich D et al. | [The effect of lacquer coatings on indoor air quality using as example radiator lacquers]. | 1982 | Schriftenr Ver Wasser Boden Lufthyg | pmid:7184167 |
Loidl P et al. | Cell-cycle-dependent effects of sodium-n-butyrate in Physarum polycephalum. | 1982 | J. Cell. Sci. | pmid:7183689 |
Ramirez ML et al. | Chlorambucil-induced changes in chromatin methylation and their modulation by sodium butyrate. | 1982 | Biochem. Biophys. Res. Commun. | pmid:7181918 |
Milsted A et al. | Glycopeptide hormone production by cultured human diploid fibroblasts. | 1982 | J. Cell. Physiol. | pmid:7174742 |
Pantazis P and Bonner WM | Butyrate-induced histone hyperacetylation in human and mouse cells: estimation of putative sites of histone acetylation in vivo. | 1982 | J. Cell. Biochem. | pmid:7169496 |
Osdoby P et al. | Isolated osteoclasts and their presumed progenitor cells, the monocyte, in culture. | 1982 | J. Exp. Zool. | pmid:7153726 |
Otto DA and Ontko JA | Structure-function relations between fatty acid oxidation and the mitochondrial inner-membrane--matrix region. | 1982 | Eur. J. Biochem. | pmid:7151811 |
Touw JJ et al. | Butyrate: a cytotoxin for Vero cells produced by Bacteroides gingivalis and Bacteroides asaccharolyticus. | 1982 | Antonie Van Leeuwenhoek | pmid:7149698 |
Williams JI and Friedberg EC | Increased levels of unscheduled DNA synthesis in UV-irradiated human fibroblasts pretreated with sodium butyrate. | 1982 | Photochem. Photobiol. | pmid:7146112 |
Saudubray JM et al. | Oxidation of fatty acids in cultured fibroblasts: a model system for the detection and study of defects in oxidation. | 1982 | Pediatr. Res. | pmid:7145511 |
Smerdon MJ et al. | Sodium butyrate stimulates DNA repair in UV-irradiated normal and xeroderma pigmentosum human fibroblasts. | 1982 | J. Biol. Chem. | pmid:7142158 |
Covault J et al. | Effects of histone hyperacetylation and hypoacetylation on RNA synthesis in HTC cells. | 1982 | J. Biol. Chem. | pmid:7142157 |
Littlefield BA et al. | Lack of effect of butyrate on S phase DNA synthesis despite presence of histone hyperacetylation. | 1982 | Exp. Cell Res. | pmid:7140840 |
Vinores SA et al. | Butyrate-induced increase in neuron-specific enolase and ornithine decarboxylase in anaplastic glioma cells. | 1982 | Brain Res. | pmid:7139340 |
Herz F and Halwer M | Synergistic induction of alkaline phosphatase in colonic carcinoma cells by sodium butyrate and hyperosmolality. | 1982 | Biochim. Biophys. Acta | pmid:7138912 |
Edson DC and Smith JW | Comparison of concentration procedures for detection of Schistosoma mansoni eggs in a CAP Parasitology Survey specimen. | 1982 | Am. J. Clin. Pathol. | pmid:7137108 |
Morita A et al. | Effect of sodium butyrate on alkaline phosphatase in HRT-18, a human rectal cancer cell line. | 1982 | Cancer Res. | pmid:7127294 |
Jiakuntorn Y and Mathias AP | The effect of sodium butyrate on acetylation in vitro of chromosomal proteins in three classes of liver nuclei from different ages of rats. | 1982 | Biochim. Biophys. Acta | pmid:7126585 |
Wynn JE et al. | Synthesis and bioevaluation of a series of fatty acid esters of p-[N,N-bis(2-chloroethyl)amino]phenol. | 1982 | J Pharm Sci | pmid:7120060 |
Morikawa M et al. | A study of esterase--its application to biotransformation of midecamycin derivatives. | 1982 | J. Pharmacobio-dyn. | pmid:7120031 |
Cistola DP et al. | Ionization behavior of aqueous short-chain carboxylic acids: a carbon-13 NMR study. | 1982 | J. Lipid Res. | pmid:7119577 |
Bode J et al. | Links between effects of butyrate on histone hyperacetylation and regulation of interferon synthesis in Namalva and FS-4 cell lines. | 1982 | J. Interferon Res. | pmid:7119504 |
Sugden MC and Watts DI | Effects of L-alanine on ketogenesis in vitro. | 1982 | Biochim. Biophys. Acta | pmid:7115774 |
Solo AJ et al. | Relative affinity of 17 alpha- and/or 21-esters and 17 alpha, 21-diesters of cortisol for a glucocorticoid receptor from rat thymocytes. | 1982 | J. Med. Chem. | pmid:7097729 |
Wakelam MJ and Pette D | The breakdown of phosphatidylinositol in myoblasts stimulated to fuse by the addition of Ca2+. | 1982 | Biochem. J. | pmid:7092841 |
Takahara N et al. | Alkaline phosphatase activity in cultured meningioma cells. | 1982 | Acta Neuropathol. | pmid:7090741 |
Perry M and Chalkley R | Histone acetylation increases the solubility of chromatin and occurs sequentially over most of the chromatin. A novel model for the biological role of histone acetylation. | 1982 | J. Biol. Chem. | pmid:7085629 |