butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Ohata A et al. | Short-chain fatty acids alter tight junction permeability in intestinal monolayer cells via lipoxygenase activation. | Nutrition | pmid:15975492 | |
Jolly RA et al. | Microvesicular steatosis induced by a short chain fatty acid: effects on mitochondrial function and correlation with gene expression. | Toxicol Pathol | pmid:15503661 | |
NofrarÃas M et al. | Long-term intake of resistant starch improves colonic mucosal integrity and reduces gut apoptosis and blood immune cells. | Nutrition | pmid:17936196 | |
Mangian HF and Tappenden KA | Butyrate increases GLUT2 mRNA abundance by initiating transcription in Caco2-BBe cells. | JPEN J Parenter Enteral Nutr | pmid:19892901 | |
Singh NP and Lai HC | Synergistic cytotoxicity of artemisinin and sodium butyrate on human cancer cells. | Anticancer Res. | pmid:16309236 | |
Jeon JH et al. | Characterization and its potential application of two esterases derived from the arctic sediment metagenome. | Mar. Biotechnol. | pmid:18814017 | |
Orchel A et al. | Influence of sodium butyrate on antioxidative enzymes activity in Caco-2 cell lines. | Acta Pol Pharm | pmid:17357609 | |
Scharlau D et al. | Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre. | Mutat. Res. | pmid:19383551 | |
Gennari L et al. | Total extract of Beta vulgaris var. cicla seeds versus its purified phenolic components: antioxidant activities and antiproliferative effects against colon cancer cells. | Phytochem Anal | pmid:21337646 | |
Munn AJ et al. | Hindgut plasticity in wallabies fed hay either unchopped or ground and pelleted: fiber is not the only factor. | Physiol. Biochem. Zool. | pmid:19331583 |