butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Jakobsdottir G et al. | Propionic and butyric acids, formed in the caecum of rats fed highly fermentable dietary fibre, are reflected in portal and aortic serum. | 2013 | Br. J. Nutr. | pmid:23531375 |
Okazaki Y et al. | Burdock fermented by Aspergillus awamori elevates cecal Bifidobacterium, and reduces fecal deoxycholic acid and adipose tissue weight in rats fed a high-fat diet. | 2013 | Biosci. Biotechnol. Biochem. | pmid:23291748 |
Balaraman E et al. | Catalytic transformation of alcohols to carboxylic acid salts and H2 using water as the oxygen atom source. | 2013 | Nat Chem | pmid:23344447 |
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Yoneda S et al. | Effects of short-chain fatty acids on Actinomyces naeslundii biofilm formation. | 2013 | Mol Oral Microbiol | pmid:23731652 |
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Muhammad A et al. | Novel fluorescent membrane for metronidazole sensing prepared by covalent immobilization of a pyrenebutyric acid derivative. | 2013 | J Fluoresc | pmid:23471624 |
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Perona M et al. | Improvement of the boron neutron capture therapy (BNCT) by the previous administration of the histone deacetylase inhibitor sodium butyrate for the treatment of thyroid carcinoma. | 2013 | Radiat Environ Biophys | pmid:23636505 |
Maliwal BP et al. | Long-lived bright red emitting azaoxa-triangulenium fluorophores. | 2013 | PLoS ONE | pmid:23667570 |
Arivazhagan G et al. | A probe on the intermolecular forces in diisopropyl ether-n-butyric acid mixture by dielectric, FTIR studies and quantum chemical calculations. | 2013 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:23295216 |
Cueno ME et al. | Butyric acid retention in gingival tissue induces oxidative stress in jugular blood mitochondria. | 2013 | Cell Stress Chaperones | pmid:23397230 |
AteÅŸ S et al. | Enhanced ethyl butyrate production using immobilized lipase. | 2013 | Artif Cells Nanomed Biotechnol | pmid:23305408 |
Pappu VK et al. | Butyric acid esterification kinetics over Amberlyst solid acid catalysts: the effect of alcohol carbon chain length. | 2013 | Bioresour. Technol. | pmid:23380294 |
Sharma P et al. | Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site. | 2013 | Arch. Biochem. Biophys. | pmid:23149273 |
Lim JH et al. | Refactoring redox cofactor regeneration for high-yield biocatalysis of glucose to butyric acid in Escherichia coli. | 2013 | Bioresour. Technol. | pmid:23127832 |
Zhang Z and Wu WS | Sodium butyrate promotes generation of human induced pluripotent stem cells through induction of the miR302/367 cluster. | 2013 | Stem Cells Dev. | pmid:23534850 |
Coskun T et al. | Carbodeoxygenation of biomass: the carbonylation of glycerol and higher polyols to monocarboxylic acids. | 2013 | Chemistry | pmid:23536394 |
Ximenes JC et al. | Valproic acid: an anticonvulsant drug with potent antinociceptive and anti-inflammatory properties. | 2013 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:23584602 |
Itzhak Y et al. | Sodium butyrate-induced histone acetylation strengthens the expression of cocaine-associated contextual memory. | 2013 | Neurobiol Learn Mem | pmid:23567105 |
Paskova L et al. | Different effect of sodium butyrate on cancer and normal prostate cells. | 2013 | Toxicol In Vitro | pmid:23524101 |
Wang P et al. | Trichostatin A protects against cisplatin-induced ototoxicity by regulating expression of genes related to apoptosis and synaptic function. | 2013 | Neurotoxicology | pmid:23558232 |
de Conti A et al. | The chemopreventive activity of the butyric acid prodrug tributyrin in experimental rat hepatocarcinogenesis is associated with p53 acetylation and activation of the p53 apoptotic signaling pathway. | 2013 | Carcinogenesis | pmid:23568954 |
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Mishiro T et al. | Butyric acid attenuates intestinal inflammation in murine DSS-induced colitis model via milk fat globule-EGF factor 8. | 2013 | Lab. Invest. | pmid:23752130 |
Cho KS et al. | Valproic acid induces astrocyte-dependent neurite outgrowth from cultured rat primary cortical neuron via modulation of tPA/PAI-1 activity. | 2013 | Glia | pmid:23378038 |
Oiso S et al. | Establishment of a gastric cell-based assay system for exploring inhibitors of octanoylated ghrelin production. | 2013 | J Biomol Screen | pmid:23704134 |
Haraguchi N et al. | CD49f-positive cell population efficiently enriches colon cancer-initiating cells. | 2013 | Int. J. Oncol. | pmid:23708747 |
Misra S et al. | Statistical approach to study the interactive effects of process parameters for enhanced xylitol production by Candida tropicalis and its potential for the synthesis of xylitol monoesters. | 2013 | Food Sci Technol Int | pmid:23733812 |
Robles R et al. | Effect of partially protected butyrate used as feed additive on growth and intestinal metabolism in sea bream (Sparus aurata). | 2013 | Fish Physiol. Biochem. | pmid:23737146 |
Rawłuszko AA et al. | Reduced expression of steroid sulfatase in primary colorectal cancer. | 2013 | Biomed. Pharmacother. | pmid:23916543 |
Heinrichs SC et al. | Repeated valproate treatment facilitates fear extinction under specific stimulus conditions. | 2013 | Neurosci. Lett. | pmid:23916657 |
Sharma B and Sharma PM | Arsenic toxicity induced endothelial dysfunction and dementia: pharmacological interdiction by histone deacetylase and inducible nitric oxide synthase inhibitors. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23921152 |
Tashiro Y et al. | A novel production process for optically pure L-lactic acid from kitchen refuse using a bacterial consortium at high temperatures. | 2013 | Bioresour. Technol. | pmid:23978480 |
Jang YS et al. | Metabolic engineering of Clostridium acetobutylicum for enhanced production of butyric acid. | 2013 | Appl. Microbiol. Biotechnol. | pmid:24013291 |
Stefaniková A et al. | ABT-737 accelerates butyrate-induced death of HL-60 cells. Involvement of mitochondrial apoptosis pathway. | 2013 | Gen. Physiol. Biophys. | pmid:23940089 |
Hao PP et al. | Isolation of EpCAM(+)/CD133 (-) hepatic progenitor cells. | 2013 | Mol. Cells | pmid:24293012 |
Venkataramanan KP et al. | The Clostridium small RNome that responds to stress: the paradigm and importance of toxic metabolite stress in C. acetobutylicum. | 2013 | BMC Genomics | pmid:24299206 |
Grousseau E et al. | Impact of sustaining a controlled residual growth on polyhydroxybutyrate yield and production kinetics in Cupriavidus necator. | 2013 | Bioresour. Technol. | pmid:24035890 |
Cuervo A et al. | Fiber from a regular diet is directly associated with fecal short-chain fatty acid concentrations in the elderly. | 2013 | Nutr Res | pmid:24074739 |
Dükkancı M and Gündüz G | Sonolytic degradation of butyric acid in aqueous solutions. | 2013 | J. Environ. Manage. | pmid:24029459 |
Sánchez-Tena S et al. | Green tea phenolics inhibit butyrate-induced differentiation of colon cancer cells by interacting with monocarboxylate transporter 1. | 2013 | Biochim. Biophys. Acta | pmid:23994611 |
Damiani R et al. | Enhancement of human thyrotropin synthesis by sodium butyrate addition to serum-free CHO cell culture. | 2013 | Appl. Biochem. Biotechnol. | pmid:23996121 |
Maioli M et al. | Amniotic fluid stem cells morph into a cardiovascular lineage: analysis of a chemically induced cardiac and vascular commitment. | 2013 | Drug Des Devel Ther | pmid:24101862 |
Mu D et al. | Sodium butyrate induces growth inhibition and apoptosis in human prostate cancer DU145 cells by up-regulation of the expression of annexin A1. | 2013 | PLoS ONE | pmid:24086397 |
Li H et al. | Development of phenotypic screening assays for γ-globin induction using primary human bone marrow day 7 erythroid progenitor cells. | 2013 | J Biomol Screen | pmid:24163393 |
Cheng J et al. | Synthesis and properties of macrocyclic butanoic acid conjugates as a promising delivery formulation for the nutrition of colon. | 2013 | ScientificWorldJournal | pmid:24163636 |
Kim SW et al. | Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET. | 2013 | Nucl. Med. Biol. | pmid:23906667 |
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Narvaez N et al. | Effects of extracts of Humulus lupulus (hops) and Yucca schidigera applied alone or in combination with monensin on rumen fermentation and microbial populations in vitro. | 2013 | J. Sci. Food Agric. | pmid:23483574 |
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Chen CQ et al. | Histone deacetylases inhibitor trichostatin A increases the expression of Dleu2/miR-15a/16-1 via HDAC3 in non-small cell lung cancer. | 2013 | Mol. Cell. Biochem. | pmid:23867991 |
Franco W and Pérez-DÃaz IM | Microbial interactions associated with secondary cucumber fermentation. | 2013 | J. Appl. Microbiol. | pmid:23013318 |
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Molina S et al. | Antiproliferative effect of alkylglycerols as vehicles of butyric acid on colon cancer cells. | 2013 Oct-Nov | Chem. Phys. Lipids | pmid:23973778 |
Liu J et al. | Sodium butyrate promotes the differentiation of rat bone marrow mesenchymal stem cells to smooth muscle cells through histone acetylation. | 2014 | PLoS ONE | pmid:25548915 |
Vicente F et al. | Subclinical ketosis on dairy cows in transition period in farms with contrasting butyric acid contents in silages. | 2014 | ScientificWorldJournal | pmid:25525616 |
Brocato J et al. | Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression. | 2014 | J. Biol. Chem. | pmid:25266719 |
Xu G et al. | SAHA regulates histone acetylation, Butyrylation, and protein expression in neuroblastoma. | 2014 | J. Proteome Res. | pmid:25160476 |
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Syngiridis K et al. | Favouring butyrate production for a new generation biofuel by acidogenic glucose fermentation using cells immobilised on γ-alumina. | 2014 | Bioresour. Technol. | pmid:24690582 |
Sarkar A et al. | Hippocampal HDAC4 contributes to postnatal fluoxetine-evoked depression-like behavior. | 2014 | Neuropsychopharmacology | pmid:24663010 |
Csikó G et al. | Effects of dietary sodium butyrate on hepatic biotransformation and pharmacokinetics of erythromycin in chickens. | 2014 | J. Vet. Pharmacol. Ther. | pmid:24628435 |
Han A et al. | Possible additional antidepressant-like mechanism of sodium butyrate: targeting the hippocampus. | 2014 | Neuropharmacology | pmid:24607816 |
Park HG et al. | Repeated treatment with electroconvulsive seizures induces HDAC2 expression and down-regulation of NMDA receptor-related genes through histone deacetylation in the rat frontal cortex. | 2014 | Int. J. Neuropsychopharmacol. | pmid:24606669 |
Hu WT et al. | Transient folate deprivation in combination with small-molecule compounds facilitates the generation of somatic cell-derived pluripotent stem cells in mice. | 2014 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:24710923 |
Yamamura T et al. | Sodium butyrate, a histone deacetylase inhibitor, regulates Lymphangiogenic factors in oral cancer cell line HSC-3. | 2014 | Anticancer Res. | pmid:24692699 |
Kumar P et al. | All-trans retinoic acid and sodium butyrate enhance natriuretic peptide receptor a gene transcription: role of histone modification. | 2014 | Mol. Pharmacol. | pmid:24714214 |
Dos Santos MP et al. | In vitro antitumor effect of sodium butyrate and zoledronic acid combined with traditional chemotherapeutic drugs: a paradigm of synergistic molecular targeting in the treatment of Ewing sarcoma. | 2014 | Oncol. Rep. | pmid:24316794 |
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Dostal A et al. | Iron supplementation promotes gut microbiota metabolic activity but not colitis markers in human gut microbiota-associated rats. | 2014 | Br. J. Nutr. | pmid:24555487 |
Dengler F et al. | Bicarbonate-dependent transport of acetate and butyrate across the basolateral membrane of sheep rumen epithelium. | 2014 | Acta Physiol (Oxf) | pmid:23927569 |
Yan SF et al. | HDAC inhibitor sodium butyrate augments the MEF2C enhancement of Nampt expression under hypoxia. | 2014 | Curr. Pharm. Des. | pmid:23888946 |
Drees J et al. | Butyrate stimulates the early process of the osteogenic differentiation but inhibits the biomineralization in dental follicle cells (DFCs). | 2014 | Odontology | pmid:23836050 |