butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Sarcoma 180 D012510 21 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Corneal Diseases D003316 13 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Osteosarcoma D012516 50 associated lipids
Carcinoma, Small Cell D018288 21 associated lipids
Hypothyroidism D007037 32 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Melanoma D008545 69 associated lipids
Occupational Diseases D009784 42 associated lipids
Weight Gain D015430 101 associated lipids
Brain Diseases D001927 27 associated lipids
Acidosis D000138 13 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Peritonitis D010538 38 associated lipids
Lymphoma D008223 18 associated lipids
Alzheimer Disease D000544 76 associated lipids
Dentin, Secondary D003809 2 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Leukemia D007938 74 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Gruchlik A et al. Influence of troglitazone, sodium butyrate, 5-aminosalicylic acid and BAY 11-7082 on the chemokine ENA-78/CXCL5 secretion in the intestinal subepithelial myofibroblasts. Acta Pol Pharm pmid:21229889
Kim JS et al. High-level scu-PA production by butyrate-treated serum-free culture of recombinant CHO cell line. Biotechnol. Prog. pmid:15575713
González-Pajuelo M et al. Metabolic engineering of Clostridium acetobutylicum for the industrial production of 1,3-propanediol from glycerol. Metab. Eng. pmid:16095939
Kien CL et al. Effects of the in vivo supply of butyrate on histone acetylation of cecum in piglets. JPEN J Parenter Enteral Nutr pmid:18165447
Nabandith V et al. Inhibitory effects of crude alpha-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat. Asian Pac. J. Cancer Prev. pmid:15546251
Jolly RA et al. Microvesicular steatosis induced by a short chain fatty acid: effects on mitochondrial function and correlation with gene expression. Toxicol Pathol pmid:15503661
Wang Y et al. Sodium butyrate-induced apoptosis and ultrastructural changes in MCF-7 breast cancer cells. Ultrastruct Pathol pmid:27158913
Ibrahim MA Assessment of insulin stability inside diblock copolymer PEG-PLA microspheres. Sci Pharm pmid:21179361
Fathallah H et al. Epigenetic analysis of the human alpha- and beta-globin gene clusters. Blood Cells Mol. Dis. pmid:18029204
Kim J et al. Sodium butyrate regulates androgen receptor expression and cell cycle arrest in human prostate cancer cells. Anticancer Res. pmid:17970072
Lee JS and Lee GM Effect of sodium butyrate on autophagy and apoptosis in Chinese hamster ovary cells. Biotechnol. Prog. pmid:22492702
Doble MA et al. Luminal regulation of Na(+)/H(+) exchanger gene expression in rat ileal mucosa. J. Gastrointest. Surg. pmid:12022991
Soto-Cruz O et al. Modeling of growth, lactate consumption, and volatile fatty acid production by Megasphaera elsdenii cultivated in minimal and complex media. Biotechnol. Prog. pmid:11934285
Cai L et al. Evaluation of zeolite for control of odorants emissions from simulated poultry manure storage. J. Environ. Qual. pmid:17215226
Varel VH et al. Manure odor potential and Escherichia coli concentrations in manure slurries of feedlot steers fed 40% corn wet distillers grains. J. Environ. Qual. pmid:20830936
Sarmiento-Rubiano LA et al. Dietary supplementation with sorbitol results in selective enrichment of lactobacilli in rat intestine. Res. Microbiol. pmid:17825531
Mangian HF and Tappenden KA Butyrate increases GLUT2 mRNA abundance by initiating transcription in Caco2-BBe cells. JPEN J Parenter Enteral Nutr pmid:19892901
Kodama N et al. Induction of myeloperoxidase and nitrotyrosine formation in a human eosinophilic leukemia cell line, EoL-1. Cell Biochem. Funct. pmid:15027099
Fontanellas A et al. Hemoglobin content is increased in the human erythroleukemia K562 cell line by a 56.2-kD peptide from uremic plasma. Am. J. Nephrol. pmid:15024177
Jung JW et al. Augmentation of sodium butyrate-induced apoptosis by p38 MAP kinase inhibition in rat liver epithelial cells. Antioxid. Redox Signal. pmid:16356138
Vester BM et al. Evaluation of nutrient digestibility and fecal characteristics of exotic felids fed horse- or beef-based diets: use of the domestic cat as a model for exotic felids. Zoo Biol. pmid:19830746
Jeon JH et al. Characterization and its potential application of two esterases derived from the arctic sediment metagenome. Mar. Biotechnol. pmid:18814017
Liamleam W and Annachhatre AP Electron donors for biological sulfate reduction. Biotechnol. Adv. pmid:17572039
Karna E et al. The mechanism of butyrate-induced collagen biosynthesis in cultured fibroblasts. Acta Pol Pharm pmid:19719045
Miki Y et al. Butyrate inhibits oral cancer cell proliferation and regulates expression of secretory phospholipase A2-X and COX-2. Anticancer Res. pmid:17595767
Rahman M et al. The fat-1 transgene in mice increases antioxidant potential, reduces pro-inflammatory cytokine levels, and enhances PPAR-gamma and SIRT-1 expression on a calorie restricted diet. Oxid Med Cell Longev pmid:20716918
Sung YH et al. Influence of down-regulation of caspase-3 by siRNAs on sodium-butyrate-induced apoptotic cell death of Chinese hamster ovary cells producing thrombopoietin. Metab. Eng. pmid:16169764
Noble R et al. Olfactory response to mushroom composting emissions as a function of chemical concentration. J. Environ. Qual. pmid:11401265
Nishinaga M et al. Establishment of a microplate-formatted cell-based immunoassay for rapid analysis of nucleotide excision repair ability in human primary cells. Photochem. Photobiol. pmid:22220555
Drozdowski LA et al. Short-chain fatty acids and total parenteral nutrition affect intestinal gene expression. JPEN J Parenter Enteral Nutr pmid:12005453
Lokshina LY et al. Modeling of anaerobic degradation of solid slaughterhouse waste: inhibition effects of long-chain fatty acids or ammonia. Appl. Biochem. Biotechnol. pmid:12794281
Karna E et al. The mechanism of butyrate-induced collagen biosynthesis in cultured fibroblasts. Acta Pol Pharm pmid:19645322
Tekucheva DN et al. Immobilized purple bacteria for light-driven H2 production from starch and potato fermentation effluents. Biotechnol. Prog. pmid:21751433
Wei ZL et al. Enhancement of sodium butyrate-induced cell death by hyperthermia in HCT 116 human colorectal cancer cells. Anticancer Res. pmid:18630528
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Wang L et al. Sodium butyrate induces human colon carcinoma HT-29 cell apoptosis through a mitochondrial pathway. J. Int. Med. Res. pmid:19589263
Han L et al. Sodium butyrate activates erythroid-specific 5-aminolevulinate synthase gene through Sp1 elements at its promoter. Blood Cells Mol. Dis. pmid:18555711
Kim GH et al. Epigenetic mechanisms of pulmonary hypertension. Pulm Circ pmid:22140624
Ghosh SK et al. Short, discontinuous exposure to butyrate effectively sensitizes latently EBV-infected lymphoma cells to nucleoside analogue antiviral agents. Blood Cells Mol. Dis. pmid:17161633
Fang HH et al. Effects of Mo(VI) on phototrophic hydrogen production by Rhodobacter sphaeroides. Environ Technol pmid:21970170
Zhang S et al. Influence of pulsed electric field treatments on the volatile compounds of milk in comparison with pasteurized processing. J. Food Sci. pmid:21535640
Lim SJ et al. Effect of butyrate on the heregulin/ErbB-mediated proliferation of human colorectal cancer cells. Mol Med Rep pmid:21475856
Bayés M and Rabasseda X Gateways to clinical trials. Methods Find Exp Clin Pharmacol pmid:18389098
Gennari L et al. Total extract of Beta vulgaris var. cicla seeds versus its purified phenolic components: antioxidant activities and antiproliferative effects against colon cancer cells. Phytochem Anal pmid:21337646
Cenkvári E et al. Investigations on the effects of Ca-soap of linseed oil on rumen fermentation in sheep and on milk composition of goats. J Anim Physiol Anim Nutr (Berl) pmid:15787990
Liu L et al. Butyrate interferes with the differentiation and function of human monocyte-derived dendritic cells. Cell. Immunol. pmid:22698927
Joachimiak R et al. Influence of sodium butyrate on hepatocellular carcinoma (hepG2) and glioblastoma (C6) cell lines in vitro. Acta Pol Pharm pmid:18323252
Sandmann G A nitromethane-based HPLC system alternative to acetonitrile for carotenoid analysis of fruit and vegetables. Phytochem Anal pmid:20310077
Sanduja S et al. The roles of TTP and BRF proteins in regulated mRNA decay. Wiley Interdiscip Rev RNA pmid:21278925
Bartholome AL et al. Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal piglets. JPEN J Parenter Enteral Nutr pmid:15291402