butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gruchlik A et al. | Influence of troglitazone, sodium butyrate, 5-aminosalicylic acid and BAY 11-7082 on the chemokine ENA-78/CXCL5 secretion in the intestinal subepithelial myofibroblasts. | Acta Pol Pharm | pmid:21229889 | |
Kim JS et al. | High-level scu-PA production by butyrate-treated serum-free culture of recombinant CHO cell line. | Biotechnol. Prog. | pmid:15575713 | |
González-Pajuelo M et al. | Metabolic engineering of Clostridium acetobutylicum for the industrial production of 1,3-propanediol from glycerol. | Metab. Eng. | pmid:16095939 | |
Kien CL et al. | Effects of the in vivo supply of butyrate on histone acetylation of cecum in piglets. | JPEN J Parenter Enteral Nutr | pmid:18165447 | |
Nabandith V et al. | Inhibitory effects of crude alpha-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat. | Asian Pac. J. Cancer Prev. | pmid:15546251 | |
Jolly RA et al. | Microvesicular steatosis induced by a short chain fatty acid: effects on mitochondrial function and correlation with gene expression. | Toxicol Pathol | pmid:15503661 | |
Wang Y et al. | Sodium butyrate-induced apoptosis and ultrastructural changes in MCF-7 breast cancer cells. | Ultrastruct Pathol | pmid:27158913 | |
Ibrahim MA | Assessment of insulin stability inside diblock copolymer PEG-PLA microspheres. | Sci Pharm | pmid:21179361 | |
Fathallah H et al. | Epigenetic analysis of the human alpha- and beta-globin gene clusters. | Blood Cells Mol. Dis. | pmid:18029204 | |
Kim J et al. | Sodium butyrate regulates androgen receptor expression and cell cycle arrest in human prostate cancer cells. | Anticancer Res. | pmid:17970072 | |
Lee JS and Lee GM | Effect of sodium butyrate on autophagy and apoptosis in Chinese hamster ovary cells. | Biotechnol. Prog. | pmid:22492702 | |
Doble MA et al. | Luminal regulation of Na(+)/H(+) exchanger gene expression in rat ileal mucosa. | J. Gastrointest. Surg. | pmid:12022991 | |
Soto-Cruz O et al. | Modeling of growth, lactate consumption, and volatile fatty acid production by Megasphaera elsdenii cultivated in minimal and complex media. | Biotechnol. Prog. | pmid:11934285 | |
Cai L et al. | Evaluation of zeolite for control of odorants emissions from simulated poultry manure storage. | J. Environ. Qual. | pmid:17215226 | |
Varel VH et al. | Manure odor potential and Escherichia coli concentrations in manure slurries of feedlot steers fed 40% corn wet distillers grains. | J. Environ. Qual. | pmid:20830936 | |
Sarmiento-Rubiano LA et al. | Dietary supplementation with sorbitol results in selective enrichment of lactobacilli in rat intestine. | Res. Microbiol. | pmid:17825531 | |
Mangian HF and Tappenden KA | Butyrate increases GLUT2 mRNA abundance by initiating transcription in Caco2-BBe cells. | JPEN J Parenter Enteral Nutr | pmid:19892901 | |
Kodama N et al. | Induction of myeloperoxidase and nitrotyrosine formation in a human eosinophilic leukemia cell line, EoL-1. | Cell Biochem. Funct. | pmid:15027099 | |
Fontanellas A et al. | Hemoglobin content is increased in the human erythroleukemia K562 cell line by a 56.2-kD peptide from uremic plasma. | Am. J. Nephrol. | pmid:15024177 | |
Jung JW et al. | Augmentation of sodium butyrate-induced apoptosis by p38 MAP kinase inhibition in rat liver epithelial cells. | Antioxid. Redox Signal. | pmid:16356138 | |
Vester BM et al. | Evaluation of nutrient digestibility and fecal characteristics of exotic felids fed horse- or beef-based diets: use of the domestic cat as a model for exotic felids. | Zoo Biol. | pmid:19830746 | |
Jeon JH et al. | Characterization and its potential application of two esterases derived from the arctic sediment metagenome. | Mar. Biotechnol. | pmid:18814017 | |
Liamleam W and Annachhatre AP | Electron donors for biological sulfate reduction. | Biotechnol. Adv. | pmid:17572039 | |
Karna E et al. | The mechanism of butyrate-induced collagen biosynthesis in cultured fibroblasts. | Acta Pol Pharm | pmid:19719045 | |
Miki Y et al. | Butyrate inhibits oral cancer cell proliferation and regulates expression of secretory phospholipase A2-X and COX-2. | Anticancer Res. | pmid:17595767 | |
Rahman M et al. | The fat-1 transgene in mice increases antioxidant potential, reduces pro-inflammatory cytokine levels, and enhances PPAR-gamma and SIRT-1 expression on a calorie restricted diet. | Oxid Med Cell Longev | pmid:20716918 | |
Sung YH et al. | Influence of down-regulation of caspase-3 by siRNAs on sodium-butyrate-induced apoptotic cell death of Chinese hamster ovary cells producing thrombopoietin. | Metab. Eng. | pmid:16169764 | |
Noble R et al. | Olfactory response to mushroom composting emissions as a function of chemical concentration. | J. Environ. Qual. | pmid:11401265 | |
Nishinaga M et al. | Establishment of a microplate-formatted cell-based immunoassay for rapid analysis of nucleotide excision repair ability in human primary cells. | Photochem. Photobiol. | pmid:22220555 | |
Drozdowski LA et al. | Short-chain fatty acids and total parenteral nutrition affect intestinal gene expression. | JPEN J Parenter Enteral Nutr | pmid:12005453 | |
Lokshina LY et al. | Modeling of anaerobic degradation of solid slaughterhouse waste: inhibition effects of long-chain fatty acids or ammonia. | Appl. Biochem. Biotechnol. | pmid:12794281 | |
Karna E et al. | The mechanism of butyrate-induced collagen biosynthesis in cultured fibroblasts. | Acta Pol Pharm | pmid:19645322 | |
Tekucheva DN et al. | Immobilized purple bacteria for light-driven H2 production from starch and potato fermentation effluents. | Biotechnol. Prog. | pmid:21751433 | |
Wei ZL et al. | Enhancement of sodium butyrate-induced cell death by hyperthermia in HCT 116 human colorectal cancer cells. | Anticancer Res. | pmid:18630528 | |
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Wang L et al. | Sodium butyrate induces human colon carcinoma HT-29 cell apoptosis through a mitochondrial pathway. | J. Int. Med. Res. | pmid:19589263 | |
Han L et al. | Sodium butyrate activates erythroid-specific 5-aminolevulinate synthase gene through Sp1 elements at its promoter. | Blood Cells Mol. Dis. | pmid:18555711 | |
Kim GH et al. | Epigenetic mechanisms of pulmonary hypertension. | Pulm Circ | pmid:22140624 | |
Ghosh SK et al. | Short, discontinuous exposure to butyrate effectively sensitizes latently EBV-infected lymphoma cells to nucleoside analogue antiviral agents. | Blood Cells Mol. Dis. | pmid:17161633 | |
Fang HH et al. | Effects of Mo(VI) on phototrophic hydrogen production by Rhodobacter sphaeroides. | Environ Technol | pmid:21970170 | |
Zhang S et al. | Influence of pulsed electric field treatments on the volatile compounds of milk in comparison with pasteurized processing. | J. Food Sci. | pmid:21535640 | |
Lim SJ et al. | Effect of butyrate on the heregulin/ErbB-mediated proliferation of human colorectal cancer cells. | Mol Med Rep | pmid:21475856 | |
Bayés M and Rabasseda X | Gateways to clinical trials. | Methods Find Exp Clin Pharmacol | pmid:18389098 | |
Gennari L et al. | Total extract of Beta vulgaris var. cicla seeds versus its purified phenolic components: antioxidant activities and antiproliferative effects against colon cancer cells. | Phytochem Anal | pmid:21337646 | |
Cenkvári E et al. | Investigations on the effects of Ca-soap of linseed oil on rumen fermentation in sheep and on milk composition of goats. | J Anim Physiol Anim Nutr (Berl) | pmid:15787990 | |
Liu L et al. | Butyrate interferes with the differentiation and function of human monocyte-derived dendritic cells. | Cell. Immunol. | pmid:22698927 | |
Joachimiak R et al. | Influence of sodium butyrate on hepatocellular carcinoma (hepG2) and glioblastoma (C6) cell lines in vitro. | Acta Pol Pharm | pmid:18323252 | |
Sandmann G | A nitromethane-based HPLC system alternative to acetonitrile for carotenoid analysis of fruit and vegetables. | Phytochem Anal | pmid:20310077 | |
Sanduja S et al. | The roles of TTP and BRF proteins in regulated mRNA decay. | Wiley Interdiscip Rev RNA | pmid:21278925 | |
Bartholome AL et al. | Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal piglets. | JPEN J Parenter Enteral Nutr | pmid:15291402 |