butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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González LA et al. | Increasing sodium bicarbonate level in high-concentrate diets for heifers. I. Effects on intake, water consumption and ruminal fermentation. | 2008 | Animal | pmid:22443595 |
Zhou YW et al. | Effects of disodium fumarate on ruminal fermentation and microbial communities in sheep fed on high-forage diets. | 2012 | Animal | pmid:22558929 |
He B et al. | Effects of sodium butyrate supplementation on reproductive performance and colostrum composition in gilts. | 2016 | Animal | pmid:27040131 |
Liangzhan S et al. | Effect of substitution of oat hulls for traditional fiber source on digestion and performance of fattening rabbits. | 2017 | Animal | pmid:27821223 |
Lallès JP et al. | Impact of bioactive substances on the gastrointestinal tract and performance of weaned piglets: a review. | 2009 | Animal | pmid:22443548 |
Niwińska B et al. | Review: Exogenous butyrate: implications for the functional development of ruminal epithelium and calf performance. | 2017 | Animal | pmid:28193308 |
Volek Z et al. | Effect of a starter diet supplementation with mannan-oligosaccharide or inulin on health status, caecal metabolism, digestibility of nutrients and growth of early weaned rabbits. | 2007 | Animal | pmid:22444409 |
Bovera F et al. | Effect of mannanoligosaccharides supplementation on caecal microbial activity of rabbits. | 2010 | Animal | pmid:22444699 |
GarcÃa V et al. | Potential of carvacrol to modify in vitro rumen fermentation as compared with monensin. | 2007 | Animal | pmid:22444468 |
Gidenne T and Feugier A | Feed restriction strategy in the growing rabbit. 1. Impact on digestion, rate of passage and microbial activity. | 2009 | Animal | pmid:22444373 |
Li L et al. | Functional modulation of ES-derived hepatocyte lineage cells via substrate compliance alteration. | 2008 | Ann Biomed Eng | pmid:18266108 |
Nakai T et al. | Changes in CA125 release and surface expression caused by drugs in uterine cervix adenocarcinoma cells. | 1993 | Ann Nucl Med | pmid:8217487 |
Hales RH | Gas-permeable cellulose acetate butyrate (CAB) contact lenses. | 1977 | Ann Ophthalmol | pmid:900727 |
Shons AR et al. | A rigid transparent face mask for control of scar hypertrophy. | 1981 | Ann Plast Surg | pmid:7235550 |
Chapman MA | The role of the colonic flora in maintaining a healthy large bowel mucosa. | 2001 | Ann R Coll Surg Engl | pmid:11320933 |
WILLIAMSON J and LOURIE EM | Interference with the trypanocidal action of gamma-(p-arsenosophenyl) butyric acid by p-aminobenzoic acid. | 1946 | Ann Trop Med Parasitol | pmid:20997909 |
van Dongen JT et al. | Transcript and metabolite profiling of the adaptive response to mild decreases in oxygen concentration in the roots of arabidopsis plants. | 2009 | Ann. Bot. | pmid:18660497 |
Chen CH et al. | Basic fibroblast growth factor inhibits p38-mediated cell differentiation and growth inhibition by activin A but not by histone deacetylase inhibitors in CML cells. | 2008 | Ann. Hematol. | pmid:17929017 |
Ferreira AC et al. | Histone deacetylase inhibitor prevents cell growth in Burkitt's lymphoma by regulating PI3K/Akt pathways and leads to upregulation of miR-143, miR-145, and miR-101. | 2014 | Ann. Hematol. | pmid:24577510 |
Janati-Idrissi R et al. | [Selection of mutants of Clostridium acetobutylicum defective in production of acetone]. | 1987 May-Jun | Ann. Inst. Pasteur Microbiol. | pmid:3620201 |
Jackson DE and Srienc F | Novel methods to synthesize polyhydroxyalkanoates. | 1994 | Ann. N. Y. Acad. Sci. | pmid:7832504 |
Rajendran VM and Binder HJ | Characterization and molecular localization of anion transporters in colonic epithelial cells. | 2000 | Ann. N. Y. Acad. Sci. | pmid:11193571 |
Papoutsakis ET et al. | Transport of substrates and metabolites and their effect on cell metabolism (in butyric-acid and methylotrophic fermentations). | 1987 | Ann. N. Y. Acad. Sci. | pmid:2829684 |
Perrine SP et al. | Fetal globin gene inducers: novel agents and new potential. | 2010 | Ann. N. Y. Acad. Sci. | pmid:20712788 |
Scher W and Waxman S | Effects of dexamethasone and phorbol myristate acetate on the induction of differentiation in mouse erythroleukemic cells by dimethyl sulfoxide, proteases, and other compounds. | 1983 | Ann. N. Y. Acad. Sci. | pmid:6349493 |
Plöger S et al. | Microbial butyrate and its role for barrier function in the gastrointestinal tract. | 2012 | Ann. N. Y. Acad. Sci. | pmid:22731715 |
Pinthong D et al. | Complex interaction of alpha(2)-adrenoceptor binding sites with bovine brain and lung extracts containing clonidine-displacing substance. | 2003 | Ann. N. Y. Acad. Sci. | pmid:15028590 |
Perrine SP et al. | Stopping the biologic clock for globin gene switching. | 1990 | Ann. N. Y. Acad. Sci. | pmid:1705405 |
Perrine SP et al. | Induction of fetal globin in beta-thalassemia: Cellular obstacles and molecular progress. | 2005 | Ann. N. Y. Acad. Sci. | pmid:16339673 |
Portois L et al. | Glucose activation of the glucagon receptor gene: functional dissimilarity with several other glucose response elements. | 2006 | Ann. N. Y. Acad. Sci. | pmid:16888215 |
Walter KA et al. | Studies of recombinant Clostridium acetobutylicum with increased dosages of butyrate formation genes. | 1994 | Ann. N. Y. Acad. Sci. | pmid:8010698 |
Han KH et al. | Feeding potato flakes affects cecal short-chain fatty acids, microflora and fecal bile acids in rats. | 2008 | Ann. Nutr. Metab. | pmid:18235187 |
Reynier MO et al. | Influence of lipid-rich diets on intestinal cholesterol uptake. | 1988 | Ann. Nutr. Metab. | pmid:3355108 |
Khan MZ et al. | Induction of phenotypic changes in SCLC cell lines in vitro by hexamethylene bisacetamide, sodium butyrate, and cyclic AMP. | 1993 | Ann. Oncol. | pmid:8394737 |
Wang XM et al. | Effects of 5-azacytidine and butyrate on differentiation and apoptosis of hepatic cancer cell lines. | 1998 | Ann. Surg. | pmid:9637556 |
Nguyen KA et al. | Dietary fiber enhances a tumor suppressor signaling pathway in the gut. | 2006 | Ann. Surg. | pmid:16632996 |
Bode BP and Souba WW | Modulation of cellular proliferation alters glutamine transport and metabolism in human hepatoma cells. | 1994 | Ann. Surg. | pmid:7944654 |
Haraguchi N et al. | CD133+CD44+ population efficiently enriches colon cancer initiating cells. | 2008 | Ann. Surg. Oncol. | pmid:18663533 |
Sanderson IR and Naik S | Dietary regulation of intestinal gene expression. | 2000 | Annu. Rev. Nutr. | pmid:10940337 |
Tukey RH and Strassburg CP | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. | 2000 | Annu. Rev. Pharmacol. Toxicol. | pmid:10836148 |
Tolstykh IV et al. | [Extraction of rifamycin B from native and aqueous solutions]. | 1975 | Antibiotiki | pmid:237467 |
Vatin AE and Filatov PP | [Pharmacokinetics of C14-olivomycin in the body of mice with lymphosarcoma (L10-1 strain)]. | 1975 | Antibiotiki | pmid:1173211 |
Sjöholm A | Sodium butyrate inhibits rat insulinoma cell proliferation without affecting the cellular insulin content or insulin release. | 1993 | Anticancer Drugs | pmid:8490204 |
Fagot D et al. | Antiproliferative effects of sodium butyrate in adriamycin-sensitive and -resistant human cancer cell lines. | 1994 | Anticancer Drugs | pmid:7858287 |
Massart C et al. | Effect of all-trans retinoic acid and sodium butyrate in vitro and in vivo on thyroid carcinoma xenografts. | 2006 | Anticancer Drugs | pmid:16702813 |
Serpe L et al. | Cholesteryl butyrate solid lipid nanoparticles as a butyric acid pro-drug: effects on cell proliferation, cell-cycle distribution and c-myc expression in human leukemic cells. | 2004 | Anticancer Drugs | pmid:15166628 |
Dong QG et al. | Isolation of a mitomycin-resistant human lung adenocarcinoma cell subline to investigate the modulation by sodium butyrate of cell growth and drug resistance. | 1993 | Anticancer Drugs | pmid:8298162 |
Gonçalves P et al. | The effect of clotrimazole on energy substrate uptake and carcinogenesis in intestinal epithelial cells. | 2012 | Anticancer Drugs | pmid:22075978 |
Massart C et al. | Effect of sodium butyrate on doxorubicin resistance and expression of multidrug resistance genes in thyroid carcinoma cells. | 2005 | Anticancer Drugs | pmid:15711177 |
Wei ZL et al. | Enhancement of sodium butyrate-induced cell death by hyperthermia in HCT 116 human colorectal cancer cells. | Anticancer Res. | pmid:18630528 |