butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Calabresse C et al. | Butyric acid and its monosaccharide ester induce apoptosis in the HL-60 cell line. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8363611 |
Wiekowski M et al. | Requirements for promoter activity in mouse oocytes and embryos distinguish paternal pronuclei from maternal and zygotic nuclei. | 1993 | Dev. Biol. | pmid:8365573 |
Schmidt JE and Ahring BK | Effects of hydrogen and formate on the degradation of propionate and butyrate in thermophilic granules from an upflow anaerobic sludge blanket reactor. | 1993 | Appl. Environ. Microbiol. | pmid:8368842 |
Laughlin MA et al. | Sodium butyrate treatment of cells latently infected with HIV-1 results in the expression of unspliced viral RNA. | 1993 | Virology | pmid:8372431 |
Barnard JA and Warwick G | Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells. | 1993 | Cell Growth Differ. | pmid:8373733 |
Nishina Y et al. | The induction of jun genes during the reversible changes induced with sodium butyrate on the differentiation of F9 cells. | 1993 | Exp. Cell Res. | pmid:8375477 |
Griner RD et al. | The role of short chain fatty acid substrates in aerobic and glycolytic metabolism in primary cultures of renal proximal tubule cells. | 1993 | In Vitro Cell. Dev. Biol. Anim. | pmid:8376317 |
Heruth DP et al. | Sodium butyrate causes an increase in the block to transcriptional elongation in the c-myc gene in SW837 rectal carcinoma cells. | 1993 | J. Biol. Chem. | pmid:8376401 |
Darcy-Vrillon B et al. | Metabolic characteristics of pig colonocytes after adaptation to a high fiber diet. | 1993 | J. Nutr. | pmid:8381478 |
Gaudet SJ et al. | Differential regulation of arylamine and arylalkylamine N-acetyltransferases in human retinoblastoma (Y-79) cells. | 1993 | Neurochem. Int. | pmid:8382984 |
Datti A and Dennis JW | Regulation of UDP-GlcNAc:Gal beta 1-3GalNAc-R beta 1-6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) in Chinese hamster ovary cells. | 1993 | J. Biol. Chem. | pmid:8383671 |
Wind JC et al. | Stimulation of calcitonin/CGRP-I and CGRP-II gene expression by dibutyryl cAMP in a human medullary thyroid carcinoma (TT) cell line. | 1993 | Mol. Cell. Endocrinol. | pmid:8386116 |
Sakamoto K et al. | Relative mitogenic activities of wild-type and retinoblastoma binding-defective SV40 T antigens in serum-deprived and senescent human diploid fibroblasts. | 1993 | Oncogene | pmid:8390037 |
Khan MZ et al. | Induction of phenotypic changes in SCLC cell lines in vitro by hexamethylene bisacetamide, sodium butyrate, and cyclic AMP. | 1993 | Ann. Oncol. | pmid:8394737 |
Rius C et al. | Differential modulation of the expression of the intermediate filament proteins vimentin and nuclear lamins A and C by differentiation inducers in human myeloid leukemia (U-937, HL-60) cells. | 1993 | Exp. Cell Res. | pmid:8395394 |
Telfer JF and Green CD | Placental alkaline phosphatase activity is inversely related to cell growth rate in HeLaS3 cervical cancer cells. | 1993 | FEBS Lett. | pmid:8396040 |
Hague A et al. | Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer. | 1993 | Int. J. Cancer | pmid:8397167 |
Salvador V et al. | Sugar composition of dietary fibre and short-chain fatty acid production during in vitro fermentation by human bacteria. | 1993 | Br. J. Nutr. | pmid:8399101 |
Polack A et al. | Regulatory elements in the immunoglobulin kappa locus induce c-myc activation and the promoter shift in Burkitt's lymphoma cells. | 1993 | EMBO J. | pmid:8404859 |
Wischmeyer P et al. | Chronic pouchitis after ileal pouch-anal anastomosis: responses to butyrate and glutamine suppositories in a pilot study. | 1993 | Mayo Clin. Proc. | pmid:8412364 |
Diener M et al. | Effect of short-chain fatty acids on cell volume and intracellular pH in rat distal colon. | 1993 | Pflugers Arch. | pmid:8414909 |
Dohi T et al. | Induction of the fundic mucosa-specific glycolipid with dimethylformamide in gastric-cancer cell lines. | 1993 | Int. J. Cancer | pmid:8416198 |
Sommerville J et al. | Histone H4 acetylation and transcription in amphibian chromatin. | 1993 | J. Cell Biol. | pmid:8421048 |
Herz F | Divergent effects of butyrate on the alkaline phosphatases of SW-620 cells. | 1993 | Biochim. Biophys. Acta | pmid:8422435 |
Blau CA et al. | Fetal hemoglobin induction with butyric acid: efficacy and toxicity. | 1993 | Blood | pmid:8422469 |
Gerharz CD et al. | Modulation of invasive potential in different clonal subpopulations of a rat rhabdomyosarcoma cell line (BA-HAN-1) by differentiation induction. | 1993 | Clin. Exp. Metastasis | pmid:8422707 |
Gálfi P et al. | Influences of extracellular matrix components on the growth and differentiation of ruminal epithelial cells in primary culture. | 1993 | Res. Vet. Sci. | pmid:8434137 |
Saito H et al. | Effect of butyric acid on induction of differentiation into eosinophil-like cells in human eosinophilic leukemia cells, EoL-1 cell line: possible role of granulocyte-macrophage colony-stimulating factor as an autocrine differentiating factor. | 1993 | Int. Arch. Allergy Immunol. | pmid:8453311 |
Utesch D et al. | Effects of sodium butyrate on DNA content, glutathione S-transferase activities, cell morphology and growth characteristics of rat liver nonparenchymal epithelial cells in vitro. | 1993 | Carcinogenesis | pmid:8453722 |
Iwai SA et al. | Changes in Hox1.6, c-jun, and Oct-3 gene expressions are associated with teratocarcinoma F9 cell differentiation in three different ways of induction. | 1993 | Exp. Cell Res. | pmid:8453995 |
Gill RK and Christakos S | Identification of sequence elements in mouse calbindin-D28k gene that confer 1,25-dihydroxyvitamin D3- and butyrate-inducible responses. | 1993 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8464915 |
Lea MA et al. | Butyramide and monobutyrin: growth inhibitory and differentiating agents. | 1993 Jan-Feb | Anticancer Res. | pmid:8476205 |
Van Lier JB et al. | Effects of acetate, propionate, and butyrate on the thermophilic anaerobic degradation of propionate by methanogenic sludge and defined cultures. | 1993 | Appl. Environ. Microbiol. | pmid:8476278 |
Hume ID et al. | Acetate, butyrate and proline uptake in the caecum and colon of prairie voles (Microtus ochrogaster). | 1993 | J. Exp. Biol. | pmid:8478602 |
Altenkirch H et al. | Experimental studies on hydrocarbon neuropathies induced by methyl-ethyl-ketone (MEK). | 1978 | J. Neurol. | pmid:84859 |
Huhtanen P et al. | Effect of increasing ruminal butyrate on milk yield and blood constituents in dairy cows fed a grass silage-based diet. | 1993 | J. Dairy Sci. | pmid:8486840 |
Kight CE and Fleming SE | Nutrient oxidation by rat intestinal epithelial cells is concentration dependent. | 1993 | J. Nutr. | pmid:8487099 |
Sjöholm A | Sodium butyrate inhibits rat insulinoma cell proliferation without affecting the cellular insulin content or insulin release. | 1993 | Anticancer Drugs | pmid:8490204 |
Yanagi S et al. | Sodium butyrate inhibits the enhancing effect of high fat diet on mammary tumorigenesis. | 1993 Jul-Aug | Oncology | pmid:8497370 |
Ford R et al. | Modulation of SPARC expression during butyrate-induced terminal differentiation of cultured human keratinocytes: regulation via a TGF-beta-dependent pathway. | 1993 | Exp. Cell Res. | pmid:8500547 |
Souleimani A and Asselin C | Regulation of C-fos expression by sodium butyrate in the human colon carcinoma cell line Caco-2. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8503924 |
Zon LI et al. | Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription. | 1993 | Blood | pmid:8507862 |
Desai TK et al. | Potentiation of butyrate-induced differentiation in human colon tumor cells by deoxycholate. | 1993 | Cancer Lett. | pmid:8513444 |
Khochbin S and Wolffe AP | Developmental regulation and butyrate-inducible transcription of the Xenopus histone H1(0) promoter. | 1993 | Gene | pmid:8514185 |
Petit JM et al. | mdr 1 gene-expression and villin synthesis in a colon cancer cell line differentiated by sodium butyrate. | 1993 Mar-Apr | Anticancer Res. | pmid:8517666 |
Afonso RodrÃguez JJ et al. | [Cytometric study of colonic tumors in a model of experimental colonic cancer. Impact of the diet]. | 1995 Sep-Oct | Nutr Hosp | pmid:8519854 |
Oda S et al. | Insulin and glucagon secretion in goats (Capra hircus Linnaeus) exposed to cold. | 1995 | Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. | pmid:8521249 |
Brill S et al. | Maturation-dependent changes in the regulation of liver-specific gene expression in embryonal versus adult primary liver cultures. | 1995 | Differentiation | pmid:8522072 |
Kvale D and Brandtzaeg P | Butyrate differentially affects constitutive and cytokine-induced expression of HLA molecules, secretory component (SC), and ICAM-1 in a colonic epithelial cell line (HT-29, clone m3). | 1995 | Adv. Exp. Med. Biol. | pmid:8525902 |
Olsen JC and Sechelski J | Use of sodium butyrate to enhance production of retroviral vectors expressing CFTR cDNA. | 1995 | Hum. Gene Ther. | pmid:8527478 |