butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Sarcoma 180 D012510 21 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Corneal Diseases D003316 13 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Osteosarcoma D012516 50 associated lipids
Carcinoma, Small Cell D018288 21 associated lipids
Hypothyroidism D007037 32 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Melanoma D008545 69 associated lipids
Occupational Diseases D009784 42 associated lipids
Weight Gain D015430 101 associated lipids
Brain Diseases D001927 27 associated lipids
Acidosis D000138 13 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Peritonitis D010538 38 associated lipids
Lymphoma D008223 18 associated lipids
Alzheimer Disease D000544 76 associated lipids
Dentin, Secondary D003809 2 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Leukemia D007938 74 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Calabresse C et al. Butyric acid and its monosaccharide ester induce apoptosis in the HL-60 cell line. 1993 Biochem. Biophys. Res. Commun. pmid:8363611
Wiekowski M et al. Requirements for promoter activity in mouse oocytes and embryos distinguish paternal pronuclei from maternal and zygotic nuclei. 1993 Dev. Biol. pmid:8365573
Schmidt JE and Ahring BK Effects of hydrogen and formate on the degradation of propionate and butyrate in thermophilic granules from an upflow anaerobic sludge blanket reactor. 1993 Appl. Environ. Microbiol. pmid:8368842
Laughlin MA et al. Sodium butyrate treatment of cells latently infected with HIV-1 results in the expression of unspliced viral RNA. 1993 Virology pmid:8372431
Barnard JA and Warwick G Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells. 1993 Cell Growth Differ. pmid:8373733
Nishina Y et al. The induction of jun genes during the reversible changes induced with sodium butyrate on the differentiation of F9 cells. 1993 Exp. Cell Res. pmid:8375477
Griner RD et al. The role of short chain fatty acid substrates in aerobic and glycolytic metabolism in primary cultures of renal proximal tubule cells. 1993 In Vitro Cell. Dev. Biol. Anim. pmid:8376317
Heruth DP et al. Sodium butyrate causes an increase in the block to transcriptional elongation in the c-myc gene in SW837 rectal carcinoma cells. 1993 J. Biol. Chem. pmid:8376401
Darcy-Vrillon B et al. Metabolic characteristics of pig colonocytes after adaptation to a high fiber diet. 1993 J. Nutr. pmid:8381478
Gaudet SJ et al. Differential regulation of arylamine and arylalkylamine N-acetyltransferases in human retinoblastoma (Y-79) cells. 1993 Neurochem. Int. pmid:8382984
Datti A and Dennis JW Regulation of UDP-GlcNAc:Gal beta 1-3GalNAc-R beta 1-6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) in Chinese hamster ovary cells. 1993 J. Biol. Chem. pmid:8383671
Wind JC et al. Stimulation of calcitonin/CGRP-I and CGRP-II gene expression by dibutyryl cAMP in a human medullary thyroid carcinoma (TT) cell line. 1993 Mol. Cell. Endocrinol. pmid:8386116
Sakamoto K et al. Relative mitogenic activities of wild-type and retinoblastoma binding-defective SV40 T antigens in serum-deprived and senescent human diploid fibroblasts. 1993 Oncogene pmid:8390037
Khan MZ et al. Induction of phenotypic changes in SCLC cell lines in vitro by hexamethylene bisacetamide, sodium butyrate, and cyclic AMP. 1993 Ann. Oncol. pmid:8394737
Rius C et al. Differential modulation of the expression of the intermediate filament proteins vimentin and nuclear lamins A and C by differentiation inducers in human myeloid leukemia (U-937, HL-60) cells. 1993 Exp. Cell Res. pmid:8395394
Telfer JF and Green CD Placental alkaline phosphatase activity is inversely related to cell growth rate in HeLaS3 cervical cancer cells. 1993 FEBS Lett. pmid:8396040
Hague A et al. Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer. 1993 Int. J. Cancer pmid:8397167
Salvador V et al. Sugar composition of dietary fibre and short-chain fatty acid production during in vitro fermentation by human bacteria. 1993 Br. J. Nutr. pmid:8399101
Polack A et al. Regulatory elements in the immunoglobulin kappa locus induce c-myc activation and the promoter shift in Burkitt's lymphoma cells. 1993 EMBO J. pmid:8404859
Wischmeyer P et al. Chronic pouchitis after ileal pouch-anal anastomosis: responses to butyrate and glutamine suppositories in a pilot study. 1993 Mayo Clin. Proc. pmid:8412364
Diener M et al. Effect of short-chain fatty acids on cell volume and intracellular pH in rat distal colon. 1993 Pflugers Arch. pmid:8414909
Dohi T et al. Induction of the fundic mucosa-specific glycolipid with dimethylformamide in gastric-cancer cell lines. 1993 Int. J. Cancer pmid:8416198
Sommerville J et al. Histone H4 acetylation and transcription in amphibian chromatin. 1993 J. Cell Biol. pmid:8421048
Herz F Divergent effects of butyrate on the alkaline phosphatases of SW-620 cells. 1993 Biochim. Biophys. Acta pmid:8422435
Blau CA et al. Fetal hemoglobin induction with butyric acid: efficacy and toxicity. 1993 Blood pmid:8422469
Gerharz CD et al. Modulation of invasive potential in different clonal subpopulations of a rat rhabdomyosarcoma cell line (BA-HAN-1) by differentiation induction. 1993 Clin. Exp. Metastasis pmid:8422707
Gálfi P et al. Influences of extracellular matrix components on the growth and differentiation of ruminal epithelial cells in primary culture. 1993 Res. Vet. Sci. pmid:8434137
Saito H et al. Effect of butyric acid on induction of differentiation into eosinophil-like cells in human eosinophilic leukemia cells, EoL-1 cell line: possible role of granulocyte-macrophage colony-stimulating factor as an autocrine differentiating factor. 1993 Int. Arch. Allergy Immunol. pmid:8453311
Utesch D et al. Effects of sodium butyrate on DNA content, glutathione S-transferase activities, cell morphology and growth characteristics of rat liver nonparenchymal epithelial cells in vitro. 1993 Carcinogenesis pmid:8453722
Iwai SA et al. Changes in Hox1.6, c-jun, and Oct-3 gene expressions are associated with teratocarcinoma F9 cell differentiation in three different ways of induction. 1993 Exp. Cell Res. pmid:8453995
Gill RK and Christakos S Identification of sequence elements in mouse calbindin-D28k gene that confer 1,25-dihydroxyvitamin D3- and butyrate-inducible responses. 1993 Proc. Natl. Acad. Sci. U.S.A. pmid:8464915
Lea MA et al. Butyramide and monobutyrin: growth inhibitory and differentiating agents. 1993 Jan-Feb Anticancer Res. pmid:8476205
Van Lier JB et al. Effects of acetate, propionate, and butyrate on the thermophilic anaerobic degradation of propionate by methanogenic sludge and defined cultures. 1993 Appl. Environ. Microbiol. pmid:8476278
Hume ID et al. Acetate, butyrate and proline uptake in the caecum and colon of prairie voles (Microtus ochrogaster). 1993 J. Exp. Biol. pmid:8478602
Altenkirch H et al. Experimental studies on hydrocarbon neuropathies induced by methyl-ethyl-ketone (MEK). 1978 J. Neurol. pmid:84859
Huhtanen P et al. Effect of increasing ruminal butyrate on milk yield and blood constituents in dairy cows fed a grass silage-based diet. 1993 J. Dairy Sci. pmid:8486840
Kight CE and Fleming SE Nutrient oxidation by rat intestinal epithelial cells is concentration dependent. 1993 J. Nutr. pmid:8487099
Sjöholm A Sodium butyrate inhibits rat insulinoma cell proliferation without affecting the cellular insulin content or insulin release. 1993 Anticancer Drugs pmid:8490204
Yanagi S et al. Sodium butyrate inhibits the enhancing effect of high fat diet on mammary tumorigenesis. 1993 Jul-Aug Oncology pmid:8497370
Ford R et al. Modulation of SPARC expression during butyrate-induced terminal differentiation of cultured human keratinocytes: regulation via a TGF-beta-dependent pathway. 1993 Exp. Cell Res. pmid:8500547
Souleimani A and Asselin C Regulation of C-fos expression by sodium butyrate in the human colon carcinoma cell line Caco-2. 1993 Biochem. Biophys. Res. Commun. pmid:8503924
Zon LI et al. Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription. 1993 Blood pmid:8507862
Desai TK et al. Potentiation of butyrate-induced differentiation in human colon tumor cells by deoxycholate. 1993 Cancer Lett. pmid:8513444
Khochbin S and Wolffe AP Developmental regulation and butyrate-inducible transcription of the Xenopus histone H1(0) promoter. 1993 Gene pmid:8514185
Petit JM et al. mdr 1 gene-expression and villin synthesis in a colon cancer cell line differentiated by sodium butyrate. 1993 Mar-Apr Anticancer Res. pmid:8517666
Afonso Rodríguez JJ et al. [Cytometric study of colonic tumors in a model of experimental colonic cancer. Impact of the diet]. 1995 Sep-Oct Nutr Hosp pmid:8519854
Oda S et al. Insulin and glucagon secretion in goats (Capra hircus Linnaeus) exposed to cold. 1995 Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. pmid:8521249
Brill S et al. Maturation-dependent changes in the regulation of liver-specific gene expression in embryonal versus adult primary liver cultures. 1995 Differentiation pmid:8522072
Kvale D and Brandtzaeg P Butyrate differentially affects constitutive and cytokine-induced expression of HLA molecules, secretory component (SC), and ICAM-1 in a colonic epithelial cell line (HT-29, clone m3). 1995 Adv. Exp. Med. Biol. pmid:8525902
Olsen JC and Sechelski J Use of sodium butyrate to enhance production of retroviral vectors expressing CFTR cDNA. 1995 Hum. Gene Ther. pmid:8527478