butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hayman EG et al. | Butyrate restores fibronectin at cell surface of transformed cells. | 1980 | Exp. Cell Res. | pmid:7379876 |
Kitzis A et al. | Effect of sodium butyrate on chromatin structure. | 1980 | Biochem. Biophys. Res. Commun. | pmid:7387680 |
Porteous JW | Glutamate, glutamine, aspartate, asparagine, glucose and ketone-body metabolism in chick intestinal brush-border cells. | 1980 | Biochem. J. | pmid:7470024 |
Kitzis A et al. | Localization of phosphoproteins and of protein kinases in chromatin from butyrate treated HTC cells. | 1980 | Biochem. Biophys. Res. Commun. | pmid:7470113 |
Mochizuki M et al. | Synthesis and mutagenicity of 4-(N-butylnitrosamino)-4-hydroxybutyric acid lactone, a possible activated metabolite of the proximate bladder carcinogen N-butyl-N-(3-carboxypropyl)nitrosamine. | 1980 | Cancer Res. | pmid:6765916 |
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Koshihara Y et al. | Sodium n-butyrate induces prostaglandin synthetase activity in mastocytoma P-815 cells. | 1980 | Biochim. Biophys. Acta | pmid:6768397 |
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Gazitt Y and Friend C | Polyamine biosynthesis enzymes in the induction and inhibition of differentiation in Friend erythroleukemia cells. | 1980 | Cancer Res. | pmid:6154532 |
Borenfreund E et al. | Constitutive aggregates of intermediate-sized filaments of the vimentin and cytokeratin type in cultured hepatoma cells and their dispersal by butyrate. | 1980 | Exp. Cell Res. | pmid:6155280 |
Bourgeade MF et al. | Type I and type II interferons: differential antiviral actions in transformed cells. | 1980 | J. Gen. Virol. | pmid:6155431 |
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Luka J et al. | Induction of the Epstein-Barr virus (EBV) cycle in latently infected cells by n-butyrate. | 1979 | Virology | pmid:220786 |
Giesecke D et al. | The effect of rumen epithelial development on metabolic activities and ketogenesis by the tissue in vitro. | 1979 | Comp. Biochem. Physiol., B | pmid:318452 |
Ebert PS et al. | Evidence for multiple sites of regulation of heme synthesis in murine erythroleukemia cells. | 1979 | J. Natl. Cancer Inst. | pmid:155751 |
Morioka K et al. | Erythroid differentiation and poly(ADP-ribose) synthesis in Friend leukemia cells. | 1979 | Gan | pmid:156137 |
Reeves R and Cserjesi P | Sodium butyrate induces new gene expression in Friend erythroleukemic cells. | 1979 | J. Biol. Chem. | pmid:285931 |
Hoffman R et al. | Induction of erythropoietic colonies in a human chronic myelogenous leukemia cell line. | 1979 | Blood | pmid:291442 |
Lozzio CB et al. | Effects of sodium butyrate on human chronic myelogenous leukaemia cell line K562. | 1979 | Nature | pmid:298333 |
Tralka TS et al. | Ultrastructural concomitants of sodium butyrate-enhanced ectopic production of chorionic gonadotropin and its alpha subunit human bronchogenic carcinoma (ChaGo) cells. | 1979 | J. Natl. Cancer Inst. | pmid:281577 |
Baretz BH et al. | Metabolism in rats in vivo of RS-2-methylbutyrate and n-butyrate labeled with stable isotopes at various positions. Mechanism of biosynthesis and degradation of ethylmalonyl semialdehyde and ethylmalonic acid. | 1979 | J. Biol. Chem. | pmid:429364 |
Tralka TS et al. | Sodium n-butyrate causes reversible decrease in condensed chromatin clumps in HeLa cells. | 1979 | Proc. Soc. Exp. Biol. Med. | pmid:482289 |
Boyd BF | Extended-wear contact lenses in 525 aphakic eyes. | 1979 | Am. J. Ophthalmol. | pmid:484664 |
Wijcik L et al. | Induction of alkaline phosphatase in cultured human fibroblasts. Comparison of normal cells and those from patients with cystic fibrosis. | 1979 | Biochim. Biophys. Acta | pmid:486538 |
Keane RW et al. | Isolation and transformation of primary mesenchymal cells of the chick embryo. | 1979 | Cell | pmid:487430 |
Leibovitch MP and Kruh J | Effect of sodium butyrate on myoblast growth and differentiation. | 1979 | Biochem. Biophys. Res. Commun. | pmid:454435 |
Dafforn A et al. | Aliphatic ketones are acetylcholinesterase inhibitors but not transition state analogs. | 1979 | Biochim. Biophys. Acta | pmid:465505 |
Johnston RW et al. | Associative properties of butyryl-coenzyme A synthetase from ox liver mitochondria. | 1979 | Biochim. Biophys. Acta | pmid:465508 |
Nemoto N et al. | Metabolism of benzo[A]pyrene in hamster embryo cells. Effect of the concentration of benzo[A]pyrene on its metabolism. | 1979 | Chem. Biol. Interact. | pmid:466731 |
Roediger WE and Truelove SC | Method of preparing isolated colonic epithelial cells (colonocytes) for metabolic studies. | 1979 | Gut | pmid:468074 |
Kitao C et al. | Bioconversion and biosynthesis of 16-membered macrolide antibiotics. XIII. Regulation of spiramycin I 3-hydroxyl acylase formation by glucose, butyrate, and cerulenin. | 1979 | J. Antibiot. | pmid:468735 |
Strom KA et al. | Enoyl coenzyme A reduction by bovine mammary fatty acid synthetase. Specificity and other characteristics. | 1979 | J. Biol. Chem. | pmid:468815 |
Arcus AC et al. | Long-term hormonal secretion from the autotransplanted sheep pancreas. | 1979 | Diabetologia | pmid:378741 |
Bourgeade MF et al. | Enhancement of interferon antitumor action by sodium butyrate. | 1979 | Cancer Res. | pmid:498098 |
Nutting DF et al. | In vitro effects of fatty acids on the actions of serum on rat and pig cartilage. | 1979 | Horm. Metab. Res. | pmid:499996 |
Seeds AE et al. | Changes in amniotic fluid glucose, beta-hydroxy-butyrate, glycerol, and lactate concentration in diabetic pregnancy. | 1979 | Am. J. Obstet. Gynecol. | pmid:507131 |
Mori Y et al. | Effect of sodium butyrate on the granulopoiesis of mastocytoma cells. | 1979 | Exp. Cell Res. | pmid:759213 |