butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Yan H and Ajuwon KM | Mechanism of Butyrate Stimulation of Triglyceride Storage and Adipokine Expression during Adipogenic Differentiation of Porcine Stromovascular Cells. | 2015 | PLoS ONE | pmid:26713737 |
Cui Y et al. | Interference of the Histone Deacetylase Inhibits Pollen Germination and Pollen Tube Growth in Picea wilsonii Mast. | 2015 | PLoS ONE | pmid:26710276 |
Saito K et al. | Modulation of Cytokine Secretion Allows CD4 T Cells Secreting IL-10 and IL-17 to Simultaneously Participate in Maintaining Tolerance and Immunity. | 2015 | PLoS ONE | pmid:26709703 |
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Muñoz-Rugeles L and Alvarez-Idaboy JR | A proton-electron sequential transfer mechanism: theoretical evidence about its biological relevance. | 2015 | Phys Chem Chem Phys | pmid:26456543 |
Sari O et al. | Synthesis of dihydropyrimidine α,γ-diketobutanoic acid derivatives targeting HIV integrase. | 2015 | Eur J Med Chem | pmid:26451771 |
Jin CJ et al. | Supplementation of sodium butyrate protects mice from the development of non-alcoholic steatohepatitis (NASH). | 2015 | Br. J. Nutr. | pmid:26450277 |
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Wang L et al. | Fermentation of sweet sorghum derived sugars to butyric acid at high titer and productivity by a moderate thermophile Clostridium thermobutyricum at 50°C. | 2015 | Bioresour. Technol. | pmid:26432057 |
Baroi GN et al. | Butyric acid fermentation from pretreated and hydrolysed wheat straw by an adapted Clostridium tyrobutyricum strain. | 2015 | Microb Biotechnol | pmid:26230610 |
Zhong Y et al. | Barley malt increases hindgut and portal butyric acid, modulates gene expression of gut tight junction proteins and Toll-like receptors in rats fed high-fat diets, but high advanced glycation end-products partially attenuate the effects. | 2015 | Food Funct | pmid:26227569 |
Sandoval PY et al. | Checkpoint Activation of an Unconventional DNA Replication Program in Tetrahymena. | 2015 | PLoS Genet. | pmid:26218270 |
Valvassori SS et al. | Sodium Butyrate, a Histone Deacetylase Inhibitor, Reverses Behavioral and Mitochondrial Alterations in Animal Models of Depression Induced by Early- or Late-life Stress. | 2015 | Curr Neurovasc Res | pmid:26216027 |
Qaisrani SN et al. | Diet structure, butyric acid, and fermentable carbohydrates influence growth performance, gut morphology, and cecal fermentation characteristics in broilers. | 2015 | Poult. Sci. | pmid:26175052 |
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Gonnella R et al. | PKC theta and p38 MAPK activate the EBV lytic cycle through autophagy induction. | 2015 | Biochim. Biophys. Acta | pmid:25827954 |
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Huang YW et al. | Brain isoform glycogen phosphorylase as a novel hepatic progenitor cell marker. | 2015 | PLoS ONE | pmid:25826279 |
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Cueno ME et al. | High butyric acid amounts induce oxidative stress, alter calcium homeostasis, and cause neurite retraction in nerve growth factor-treated PC12 cells. | 2015 | Cell Stress Chaperones | pmid:25808460 |
Kanika G et al. | Sodium Butyrate Ameliorates L-Arginine-Induced Pancreatitis and Associated Fibrosis in Wistar Rat: Role of Inflammation and Nitrosative Stress. | 2015 | J. Biochem. Mol. Toxicol. | pmid:25774002 |
Cao QF et al. | TRPM2 mediates histone deacetylase inhibition-induced apoptosis in bladder cancer cells. | 2015 | Cancer Biother. Radiopharm. | pmid:25760728 |
Mackmull MT et al. | Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs). | 2015 | Mol. Cell Proteomics | pmid:25755299 |
Rodrigues MF et al. | Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin A on the energy metabolism of breast cancer cells. | 2015 | J. Cell. Biochem. | pmid:25510910 |
Varela RB et al. | Sodium butyrate and mood stabilizers block ouabain-induced hyperlocomotion and increase BDNF, NGF and GDNF levels in brain of Wistar rats. | 2015 | J Psychiatr Res | pmid:25467060 |
Turon V et al. | Use of fermentative metabolites for heterotrophic microalgae growth: Yields and kinetics. | 2015 | Bioresour. Technol. | pmid:25459841 |
Zgorzynska E et al. | Docosahexaenoic acid attenuates oxidative stress and protects human gingival fibroblasts against cytotoxicity induced by hydrogen peroxide and butyric acid. | 2015 | Arch. Oral Biol. | pmid:25455128 |
Lee C et al. | Effect of 2-hydroxy-4-methylthio-butanoic acid on ruminal fermentation, bacterial distribution, digestibility, and performance of lactating dairy cows. | 2015 | J. Dairy Sci. | pmid:25434334 |
Lopes-Borges J et al. | Histone deacetylase inhibitors reverse manic-like behaviors and protect the rat brain from energetic metabolic alterations induced by ouabain. | 2015 | Pharmacol. Biochem. Behav. | pmid:25433326 |
Simon-O'Brien E et al. | The histone deacetylase inhibitor sodium butyrate decreases excessive ethanol intake in dependent animals. | 2015 | Addict Biol | pmid:25041570 |
Katsou E et al. | Coupling the treatment of low strength anaerobic effluent with fermented biowaste for nutrient removal via nitrite. | 2015 | J. Environ. Manage. | pmid:25463576 |
Xiong XR et al. | Sodium butyrate improves the cloned yak embryo viability and corrects gene expression patterns. | 2015 | Zygote | pmid:23759515 |
Stertz L et al. | Histone deacetylase activity and brain-derived neurotrophic factor (BDNF) levels in a pharmacological model of mania. | 2014 Jan-Mar | Rev Bras Psiquiatr | pmid:24346357 |
de Theije CG et al. | Altered gut microbiota and activity in a murine model of autism spectrum disorders. | 2014 | Brain Behav. Immun. | pmid:24333160 |
Zhong T et al. | Repression of contexual fear memory induced by isoflurane is accompanied by reduction in histone acetylation and rescued by sodium butyrate. | 2014 | Br J Anaesth | pmid:24838805 |
Lu R et al. | Effect of non-surgical periodontal treatment on short chain fatty acid levels in gingival crevicular fluid of patients with generalized aggressive periodontitis. | 2014 | J. Periodont. Res. | pmid:25340203 |
Machiels K et al. | A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis. | 2014 | Gut | pmid:24021287 |
Grousseau E et al. | Phosphorus limitation strategy to increase propionic acid flux towards 3-hydroxyvaleric acid monomers in Cupriavidus necator. | 2014 | Bioresour. Technol. | pmid:24365742 |
Yu M et al. | Enhancement of adriamycin cytotoxicity by sodium butyrate involves hTERT downmodulation-mediated apoptosis in human uterine cancer cells. | 2014 | Mol. Carcinog. | pmid:23359532 |
Wei Y et al. | Antidepressant-like effect of sodium butyrate is associated with an increase in TET1 and in 5-hydroxymethylation levels in the Bdnf gene. | 2014 | Int. J. Neuropsychopharmacol. | pmid:25618518 |
Procentese A et al. | Continuous xylose fermentation by Clostridium acetobutylicum--kinetics and energetics issues under acidogenesis conditions. | 2014 | Bioresour. Technol. | pmid:24852648 |
Jin H et al. | Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease. | 2014 | J. Biol. Chem. | pmid:25342743 |
Ferrario C et al. | Modulation of fecal Clostridiales bacteria and butyrate by probiotic intervention with Lactobacillus paracasei DG varies among healthy adults. | 2014 | J. Nutr. | pmid:25332478 |
Gong Q et al. | [Sodium butyrate inhibits HMGB1 expression and release and attenuates concanavalin A-induced acute liver injury in mice]. | 2014 | Sheng Li Xue Bao | pmid:25332009 |
Pal A and Dey J | Organogelation by 4-(N-tetradecanoyl)aminohydroxybutyric acids: effect of hydrogen-bonding group in the amphiphile head. | 2014 | J Phys Chem B | pmid:25310731 |
Miletta MC et al. | Butyrate increases intracellular calcium levels and enhances growth hormone release from rat anterior pituitary cells via the G-protein-coupled receptors GPR41 and 43. | 2014 | PLoS ONE | pmid:25310566 |
White MK et al. | Rad51 activates polyomavirus JC early transcription. | 2014 | PLoS ONE | pmid:25310191 |
Miltko R et al. | Can fungal zoospores be the source of energy for the rumen protozoa Eudiplodinium maggii? | 2014 | Anaerobe | pmid:24012688 |
Katzenmaier EM et al. | Impact of sodium butyrate on the network of adhesion/growth-regulatory galectins in human colon cancer in vitro. | 2014 | Anticancer Res. | pmid:25275038 |
Takuma K et al. | Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism. | 2014 | Pharmacol. Biochem. Behav. | pmid:25240644 |
Valvassori SS et al. | Sodium butyrate functions as an antidepressant and improves cognition with enhanced neurotrophic expression in models of maternal deprivation and chronic mild stress. | 2014 | Curr Neurovasc Res | pmid:25233278 |
Nankova BB et al. | Enteric bacterial metabolites propionic and butyric acid modulate gene expression, including CREB-dependent catecholaminergic neurotransmission, in PC12 cells--possible relevance to autism spectrum disorders. | 2014 | PLoS ONE | pmid:25170769 |
Bilgraer R et al. | A new approach combining LC-MS and multivariate statistical analysis for revealing changes in histone modification levels. | 2014 | Mol Biosyst | pmid:25167371 |
Lorenzo JM | Influence of the type of fiber coating and extraction time on foal dry-cured loin volatile compounds extracted by solid-phase microextraction (SPME). | 2014 | Meat Sci. | pmid:23896153 |
Khalil NA et al. | In vitro batch cultures of gut microbiota from healthy and ulcerative colitis (UC) subjects suggest that sulphate-reducing bacteria levels are raised in UC and by a protein-rich diet. | 2014 | Int J Food Sci Nutr | pmid:23941288 |
Grandner MA et al. | Sleep symptoms associated with intake of specific dietary nutrients. | 2014 | J Sleep Res | pmid:23992533 |
Peterson EC and Daugulis AJ | Demonstration of in situ product recovery of butyric acid via CO2 -facilitated pH swings and medium development in two-phase partitioning bioreactors. | 2014 | Biotechnol. Bioeng. | pmid:23996152 |
Weber TE et al. | Effects of dietary humic and butyric acid on growth performance and response to lipopolysaccharide in young pigs. | 2014 | J. Anim. Sci. | pmid:25023805 |
Nakata S et al. | Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity. | 2014 | Int. J. Oncol. | pmid:25017791 |
Gutiérrez Acosta OB et al. | Acetone utilization by sulfate-reducing bacteria: draft genome sequence of Desulfococcus biacutus and a proteomic survey of acetone-inducible proteins. | 2014 | BMC Genomics | pmid:25012398 |
Farkas O et al. | Effects of Lactobacillus plantarum 2142 and sodium n-butyrate in lipopolysaccharide-triggered inflammation: comparison of a porcine intestinal epithelial cell line and primary hepatocyte monocultures with a porcine enterohepatic co-culture system. | 2014 | J. Anim. Sci. | pmid:24987069 |
Yang F et al. | Sodium butyrate protects against toxin-induced acute liver failure in rats. | 2014 | HBPD INT | pmid:24919615 |
Peterson EC and Daugulis AJ | The use of high pressure CO2 -facilitated pH swings to enhance in situ product recovery of butyric acid in a two-phase partitioning bioreactor. | 2014 | Biotechnol. Bioeng. | pmid:24888558 |
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Utsugi C et al. | Hard-diet feeding recovers neurogenesis in the subventricular zone and olfactory functions of mice impaired by soft-diet feeding. | 2014 | PLoS ONE | pmid:24817277 |
Milbradt EL et al. | Control of Salmonella Enteritidis in turkeys using organic acids and competitive exclusion product. | 2014 | J. Appl. Microbiol. | pmid:24797347 |
Wang J et al. | Comparative effects of sodium butyrate and flavors on feed intake of lactating sows and growth performance of piglets. | 2014 | Anim. Sci. J. | pmid:24773759 |
Saini M et al. | Metabolic engineering of Escherichia coli for production of butyric acid. | 2014 | J. Agric. Food Chem. | pmid:24773075 |
Dareioti MA et al. | Effect of pH on the anaerobic acidogenesis of agroindustrial wastewaters for maximization of bio-hydrogen production: a lab-scale evaluation using batch tests. | 2014 | Bioresour. Technol. | pmid:24759638 |
Castellano JF et al. | Reassessing the effects of histone deacetylase inhibitors on hippocampal memory and cognitive aging. | 2014 | Hippocampus | pmid:24753063 |
Zhou X et al. | Comparison of the effects of high energy carbon heavy ion irradiation and Eucommia ulmoides Oliv. on biosynthesis butyric acid efficiency in Clostridium tyrobutyricum. | 2014 | Bioresour. Technol. | pmid:24704888 |
Krokowicz L et al. | Microencapsulated sodium butyrate administered to patients with diverticulosis decreases incidence of diverticulitis--a prospective randomized study. | 2014 | Int J Colorectal Dis | pmid:24343275 |
Sanchez R et al. | Differential abundance of IGF1, bile acids, and the genes involved in their signaling in the dominant follicle microenvironment of lactating cows and nulliparous heifers. | 2014 | Theriogenology | pmid:24503106 |
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Cueno ME et al. | Butyric acid-induced rat jugular blood cytosolic oxidative stress is associated with SIRT1 decrease. | 2014 | Cell Stress Chaperones | pmid:24052229 |
Lee KH et al. | Hizikia fusiformis fractions successfully improve atopic dermatitis indices in anti-CD3-stimulated splenocytes and 2,4-dinitrochlorobenzene-treated BALB/c mice. | 2014 | J. Pharm. Pharmacol. | pmid:24354475 |
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Kato R et al. | The synergistic effect of 1'-acetoxychavicol acetate and sodium butyrate on the death of human hepatocellular carcinoma cells. | 2014 | Chem. Biol. Interact. | pmid:24480522 |
Saldanha SN et al. | Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate. | 2014 | Exp. Cell Res. | pmid:24518414 |
Cerisuelo A et al. | The impact of a specific blend of essential oil components and sodium butyrate in feed on growth performance and Salmonella counts in experimentally challenged broilers. | 2014 | Poult. Sci. | pmid:24604853 |
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Liu Y et al. | Sodium butyrate enhances the acidic isoform content of recombinant human erythropoietin produced by Chinese hamster ovary cells. | 2014 | Biotechnol. Lett. | pmid:24557070 |
Hu X et al. | Histone deacetylase inhibitor sodium butyrate promotes the osteogenic differentiation of rat adipose-derived stem cells. | 2014 | Dev. Growth Differ. | pmid:24494796 |
Xiao M et al. | Sodium butyrate induces apoptosis of human colon cancer cells by modulating ERK and sphingosine kinase 2. | 2014 | Biomed. Environ. Sci. | pmid:24709100 |
Singh V et al. | Histone deacetylase inhibitors valproic acid and sodium butyrate enhance prostaglandins release in lipopolysaccharide-activated primary microglia. | 2014 | Neuroscience | pmid:24480366 |
Rivkin I et al. | Cancer cell sensitization and improved treatment efficacy by combined sodium butyrate and paclitaxel formulations is cancer-type specific. | 2014 | Int J Pharm | pmid:24370842 |
Aoyama Y et al. | Clozapine ameliorates epigenetic and behavioral abnormalities induced by phencyclidine through activation of dopamine D1 receptor. | 2014 | Int. J. Neuropsychopharmacol. | pmid:24345457 |
Górka P et al. | Effect of method of delivery of sodium butyrate on maturation of the small intestine in newborn calves. | 2014 | J. Dairy Sci. | pmid:24342681 |
Núñez-Jaramillo L et al. | Sodium butyrate into the insular cortex during conditioned taste-aversion acquisition delays aversive taste memory extinction. | 2014 | Neuroreport | pmid:24323127 |
Tariq M et al. | Synthesis, spectroscopic, X-ray crystal structure, biological and DNA interaction studies of organotin(IV) complexes of 2-(4-ethoxybenzylidene) butanoic acid. | 2014 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:24322756 |
Gagliano H et al. | High doses of the histone deacetylase inhibitor sodium butyrate trigger a stress-like response. | 2014 | Neuropharmacology | pmid:24212060 |
Tailor D et al. | Sodium butyrate induces DRP1-mediated mitochondrial fusion and apoptosis in human colorectal cancer cells. | 2014 | Mitochondrion | pmid:24177748 |
Peterson AB et al. | Dose-dependent effects of wheel running on cocaine-seeking and prefrontal cortex Bdnf exon IV expression in rats. | 2014 | Psychopharmacology (Berl.) | pmid:24173624 |
Fang CL et al. | Effects of sodium butyrate on growth performance, haematological and immunological characteristics of weanling piglets. | 2014 | J Anim Physiol Anim Nutr (Berl) | pmid:24024579 |
Meehan CJ and Beiko RG | A phylogenomic view of ecological specialization in the Lachnospiraceae, a family of digestive tract-associated bacteria. | 2014 | Genome Biol Evol | pmid:24625961 |
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