butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Arai T et al. | Actinomyces naeslundii GroEL-dependent initial attachment and biofilm formation in a flow cell system. | 2015 | J. Microbiol. Methods | pmid:25555820 |
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Lu R et al. | Effect of non-surgical periodontal treatment on short chain fatty acid levels in gingival crevicular fluid of patients with generalized aggressive periodontitis. | 2014 | J. Periodont. Res. | pmid:25340203 |
Wang C et al. | A survey of fermentation products and bacterial communities in corn silage produced in a bunker silo in China. | 2014 | Anim. Sci. J. | pmid:23638801 |
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Yu M et al. | Enhancement of adriamycin cytotoxicity by sodium butyrate involves hTERT downmodulation-mediated apoptosis in human uterine cancer cells. | 2014 | Mol. Carcinog. | pmid:23359532 |
Liu J et al. | Sodium butyrate promotes the differentiation of rat bone marrow mesenchymal stem cells to smooth muscle cells through histone acetylation. | 2014 | PLoS ONE | pmid:25548915 |
Vicente F et al. | Subclinical ketosis on dairy cows in transition period in farms with contrasting butyric acid contents in silages. | 2014 | ScientificWorldJournal | pmid:25525616 |
Szymanowska-Powałowska D et al. | Biotechnological potential of Clostridium butyricum bacteria. | 2014 | Braz. J. Microbiol. | pmid:25477923 |
Jin H et al. | Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease. | 2014 | J. Biol. Chem. | pmid:25342743 |
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Lorenzo JM | Influence of the type of fiber coating and extraction time on foal dry-cured loin volatile compounds extracted by solid-phase microextraction (SPME). | 2014 | Meat Sci. | pmid:23896153 |
Xu G et al. | SAHA regulates histone acetylation, Butyrylation, and protein expression in neuroblastoma. | 2014 | J. Proteome Res. | pmid:25160476 |
Khan S and Jena G | Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-β1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats. | 2014 | Food Chem. Toxicol. | pmid:25158305 |
Khalil NA et al. | In vitro batch cultures of gut microbiota from healthy and ulcerative colitis (UC) subjects suggest that sulphate-reducing bacteria levels are raised in UC and by a protein-rich diet. | 2014 | Int J Food Sci Nutr | pmid:23941288 |
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Chou AH et al. | Polyglutamine-expanded ataxin-3 impairs long-term depression in Purkinje neurons of SCA3 transgenic mouse by inhibiting HAT and impairing histone acetylation. | 2014 | Brain Res. | pmid:25139423 |
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Lee JM et al. | Direct hydrogenation of biomass-derived butyric acid to n-butanol over a ruthenium-tin bimetallic catalyst. | 2014 | ChemSusChem | pmid:25123894 |
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Sarkar A et al. | Hippocampal HDAC4 contributes to postnatal fluoxetine-evoked depression-like behavior. | 2014 | Neuropsychopharmacology | pmid:24663010 |
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Zhang Z et al. | Sodium butyrate facilitates reprogramming by derepressing OCT4 transactivity at the promoter of embryonic stem cell-specific miR-302/367 cluster. | 2014 | Cell Reprogram | pmid:24568633 |
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Ai B et al. | Butyric acid fermentation of sodium hydroxide pretreated rice straw with undefined mixed culture. | 2014 | J. Microbiol. Biotechnol. | pmid:24561721 |
Cerisuelo A et al. | The impact of a specific blend of essential oil components and sodium butyrate in feed on growth performance and Salmonella counts in experimentally challenged broilers. | 2014 | Poult. Sci. | pmid:24604853 |
Hong JK et al. | Effect of sodium butyrate on the assembly, charge variants, and galactosylation of antibody produced in recombinant Chinese hamster ovary cells. | 2014 | Appl. Microbiol. Biotechnol. | pmid:24557571 |
Ronzoni L et al. | Modulation of gamma globin genes expression by histone deacetylase inhibitors: an in vitro study. | 2014 | Br. J. Haematol. | pmid:24606390 |
Liu Y et al. | Sodium butyrate enhances the acidic isoform content of recombinant human erythropoietin produced by Chinese hamster ovary cells. | 2014 | Biotechnol. Lett. | pmid:24557070 |
Hu X et al. | Histone deacetylase inhibitor sodium butyrate promotes the osteogenic differentiation of rat adipose-derived stem cells. | 2014 | Dev. Growth Differ. | pmid:24494796 |
Xiao M et al. | Sodium butyrate induces apoptosis of human colon cancer cells by modulating ERK and sphingosine kinase 2. | 2014 | Biomed. Environ. Sci. | pmid:24709100 |
Singh V et al. | Histone deacetylase inhibitors valproic acid and sodium butyrate enhance prostaglandins release in lipopolysaccharide-activated primary microglia. | 2014 | Neuroscience | pmid:24480366 |
Hu WT et al. | Transient folate deprivation in combination with small-molecule compounds facilitates the generation of somatic cell-derived pluripotent stem cells in mice. | 2014 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:24710923 |
Yamamura T et al. | Sodium butyrate, a histone deacetylase inhibitor, regulates Lymphangiogenic factors in oral cancer cell line HSC-3. | 2014 | Anticancer Res. | pmid:24692699 |
Kumar P et al. | All-trans retinoic acid and sodium butyrate enhance natriuretic peptide receptor a gene transcription: role of histone modification. | 2014 | Mol. Pharmacol. | pmid:24714214 |
Dos Santos MP et al. | In vitro antitumor effect of sodium butyrate and zoledronic acid combined with traditional chemotherapeutic drugs: a paradigm of synergistic molecular targeting in the treatment of Ewing sarcoma. | 2014 | Oncol. Rep. | pmid:24316794 |
Dengler F et al. | Bicarbonate-dependent transport of acetate and butyrate across the basolateral membrane of sheep rumen epithelium. | 2014 | Acta Physiol (Oxf) | pmid:23927569 |
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Drees J et al. | Butyrate stimulates the early process of the osteogenic differentiation but inhibits the biomineralization in dental follicle cells (DFCs). | 2014 | Odontology | pmid:23836050 |