butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Yan H and Ajuwon KM | Mechanism of Butyrate Stimulation of Triglyceride Storage and Adipokine Expression during Adipogenic Differentiation of Porcine Stromovascular Cells. | 2015 | PLoS ONE | pmid:26713737 |
Cui Y et al. | Interference of the Histone Deacetylase Inhibits Pollen Germination and Pollen Tube Growth in Picea wilsonii Mast. | 2015 | PLoS ONE | pmid:26710276 |
Saito K et al. | Modulation of Cytokine Secretion Allows CD4 T Cells Secreting IL-10 and IL-17 to Simultaneously Participate in Maintaining Tolerance and Immunity. | 2015 | PLoS ONE | pmid:26709703 |
Luo H et al. | Enhancing Butanol Production under the Stress Environments of Co-Culturing Clostridium acetobutylicum/Saccharomyces cerevisiae Integrated with Exogenous Butyrate Addition. | 2015 | PLoS ONE | pmid:26489085 |
Alva-Murillo N et al. | The activation of the TLR2/p38 pathway by sodium butyrate in bovine mammary epithelial cells is involved in the reduction of Staphylococcus aureus internalization. | 2015 | Mol. Immunol. | pmid:26471700 |
Turon V et al. | Growth of Chlorella sorokiniana on a mixture of volatile fatty acids: The effects of light and temperature. | 2015 | Bioresour. Technol. | pmid:26461792 |
Muñoz-Rugeles L and Alvarez-Idaboy JR | A proton-electron sequential transfer mechanism: theoretical evidence about its biological relevance. | 2015 | Phys Chem Chem Phys | pmid:26456543 |
Sari O et al. | Synthesis of dihydropyrimidine α,γ-diketobutanoic acid derivatives targeting HIV integrase. | 2015 | Eur J Med Chem | pmid:26451771 |
Jin CJ et al. | Supplementation of sodium butyrate protects mice from the development of non-alcoholic steatohepatitis (NASH). | 2015 | Br. J. Nutr. | pmid:26450277 |
Nasser Al-Shorgani NK et al. | Improvement of the butanol production selectivity and butanol to acetone ratio (B:A) by addition of electron carriers in the batch culture of a new local isolate of Clostridium acetobutylicum YM1. | 2015 | Anaerobe | pmid:26439644 |
Wang L et al. | Fermentation of sweet sorghum derived sugars to butyric acid at high titer and productivity by a moderate thermophile Clostridium thermobutyricum at 50°C. | 2015 | Bioresour. Technol. | pmid:26432057 |
Chen Y et al. | Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice. | 2015 | Cardiovasc Diabetol | pmid:26245924 |
Wang X et al. | Sodium butyrate alleviates adipocyte inflammation by inhibiting NLRP3 pathway. | 2015 | Sci Rep | pmid:26234821 |
Regestein L et al. | Impact of butyric acid on butanol formation by Clostridium pasteurianum. | 2015 | Bioresour. Technol. | pmid:26233327 |
Baroi GN et al. | Butyric acid fermentation from pretreated and hydrolysed wheat straw by an adapted Clostridium tyrobutyricum strain. | 2015 | Microb Biotechnol | pmid:26230610 |
Zhong Y et al. | Barley malt increases hindgut and portal butyric acid, modulates gene expression of gut tight junction proteins and Toll-like receptors in rats fed high-fat diets, but high advanced glycation end-products partially attenuate the effects. | 2015 | Food Funct | pmid:26227569 |
Sandoval PY et al. | Checkpoint Activation of an Unconventional DNA Replication Program in Tetrahymena. | 2015 | PLoS Genet. | pmid:26218270 |
Valvassori SS et al. | Sodium Butyrate, a Histone Deacetylase Inhibitor, Reverses Behavioral and Mitochondrial Alterations in Animal Models of Depression Induced by Early- or Late-life Stress. | 2015 | Curr Neurovasc Res | pmid:26216027 |
Qaisrani SN et al. | Diet structure, butyric acid, and fermentable carbohydrates influence growth performance, gut morphology, and cecal fermentation characteristics in broilers. | 2015 | Poult. Sci. | pmid:26175052 |
Xu H et al. | Sodium butyrate stimulates NHE8 expression via its role on activating NHE8 basal promoter activity. | 2015 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:26159698 |
Guglielmetti S and Riso P | Reply to Conlon et al. | 2015 | J. Nutr. | pmid:26125075 |
Fukushima A et al. | Ketogenic diet does not impair spatial ability controlled by the hippocampus in male rats. | 2015 | Brain Res. | pmid:26111645 |
Steliou K et al. | Bioprotective carnitinoids: lipoic acid, butyrate, and mitochondria-targeting to treat radiation injury: mitochondrial drugs come of age. | 2015 | Drug Dev. Res. | pmid:26109467 |
Brandão FA et al. | Histone deacetylases inhibitors effects on Cryptococcus neoformans major virulence phenotypes. | 2015 | Virulence | pmid:26103530 |
Malago JJ and Sangu CL | Intraperitoneal administration of butyrate prevents the severity of acetic acid colitis in rats. | 2015 | J Zhejiang Univ Sci B | pmid:25743124 |
Castino MR et al. | Inhibition of histone deacetylases facilitates extinction and attenuates reinstatement of nicotine self-administration in rats. | 2015 | PLoS ONE | pmid:25880762 |
Ulfina GG et al. | Modulation of post-partum reproductive performance in dairy cows through supplementation of long- or short-chain fatty acids during transition period. | 2015 | J Anim Physiol Anim Nutr (Berl) | pmid:25879374 |
Blank M et al. | Enhancement of memory consolidation by the histone deacetylase inhibitor sodium butyrate in aged rats. | 2015 | Neurosci. Lett. | pmid:25837444 |
Gonnella R et al. | PKC theta and p38 MAPK activate the EBV lytic cycle through autophagy induction. | 2015 | Biochim. Biophys. Acta | pmid:25827954 |
Shimoyama T et al. | Study of the mechanisms of a Japanese traditional fermented medicine in the improvement of constipation. | 2015 | J. Gastroenterol. Hepatol. | pmid:25827805 |
Huang YW et al. | Brain isoform glycogen phosphorylase as a novel hepatic progenitor cell marker. | 2015 | PLoS ONE | pmid:25826279 |
Chen L et al. | Free and bound volatile chemicals in mulberry (Morus atropurpurea Roxb.). | 2015 | J. Food Sci. | pmid:25817411 |
Cueno ME et al. | High butyric acid amounts induce oxidative stress, alter calcium homeostasis, and cause neurite retraction in nerve growth factor-treated PC12 cells. | 2015 | Cell Stress Chaperones | pmid:25808460 |
Kanika G et al. | Sodium Butyrate Ameliorates L-Arginine-Induced Pancreatitis and Associated Fibrosis in Wistar Rat: Role of Inflammation and Nitrosative Stress. | 2015 | J. Biochem. Mol. Toxicol. | pmid:25774002 |
Cao QF et al. | TRPM2 mediates histone deacetylase inhibition-induced apoptosis in bladder cancer cells. | 2015 | Cancer Biother. Radiopharm. | pmid:25760728 |
Mackmull MT et al. | Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs). | 2015 | Mol. Cell Proteomics | pmid:25755299 |
Caminero A et al. | Differences in gluten metabolism among healthy volunteers, coeliac disease patients and first-degree relatives. | 2015 | Br. J. Nutr. | pmid:26428276 |
Rodrigues MF et al. | Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin A on the energy metabolism of breast cancer cells. | 2015 | J. Cell. Biochem. | pmid:25510910 |
Varela RB et al. | Sodium butyrate and mood stabilizers block ouabain-induced hyperlocomotion and increase BDNF, NGF and GDNF levels in brain of Wistar rats. | 2015 | J Psychiatr Res | pmid:25467060 |
Turon V et al. | Use of fermentative metabolites for heterotrophic microalgae growth: Yields and kinetics. | 2015 | Bioresour. Technol. | pmid:25459841 |
Zgorzynska E et al. | Docosahexaenoic acid attenuates oxidative stress and protects human gingival fibroblasts against cytotoxicity induced by hydrogen peroxide and butyric acid. | 2015 | Arch. Oral Biol. | pmid:25455128 |
Lee C et al. | Effect of 2-hydroxy-4-methylthio-butanoic acid on ruminal fermentation, bacterial distribution, digestibility, and performance of lactating dairy cows. | 2015 | J. Dairy Sci. | pmid:25434334 |
Lopes-Borges J et al. | Histone deacetylase inhibitors reverse manic-like behaviors and protect the rat brain from energetic metabolic alterations induced by ouabain. | 2015 | Pharmacol. Biochem. Behav. | pmid:25433326 |
Ray A et al. | Absorption spectrophotometric, fluorescence and quantum chemical investigations on non-covalent interaction between PC₇₀BM and designed diporphyrin in solution. | 2015 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:25138385 |
Simon-O'Brien E et al. | The histone deacetylase inhibitor sodium butyrate decreases excessive ethanol intake in dependent animals. | 2015 | Addict Biol | pmid:25041570 |
Szymanowska-Powałowska D and Kubiak P | Effect of 1,3-propanediol, organic acids, and ethanol on growth and metabolism of Clostridium butyricum DSP1. | 2015 | Appl. Microbiol. Biotechnol. | pmid:25524700 |
Katsou E et al. | Coupling the treatment of low strength anaerobic effluent with fermented biowaste for nutrient removal via nitrite. | 2015 | J. Environ. Manage. | pmid:25463576 |
Pawelka AJ and Huizinga JD | Induction of rhythmic transient depolarizations associated with waxing and waning of slow wave activity in intestinal smooth muscle. | 2015 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:25540235 |
Isom CE et al. | Improved conversion efficiencies for n-fatty acid reduction to primary alcohols by the solventogenic acetogen "Clostridium ragsdalei". | 2015 | J. Ind. Microbiol. Biotechnol. | pmid:25410829 |
Xiong XR et al. | Sodium butyrate improves the cloned yak embryo viability and corrects gene expression patterns. | 2015 | Zygote | pmid:23759515 |