butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Sarcoma 180 D012510 21 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Corneal Diseases D003316 13 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Osteosarcoma D012516 50 associated lipids
Carcinoma, Small Cell D018288 21 associated lipids
Hypothyroidism D007037 32 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Melanoma D008545 69 associated lipids
Occupational Diseases D009784 42 associated lipids
Weight Gain D015430 101 associated lipids
Brain Diseases D001927 27 associated lipids
Acidosis D000138 13 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Peritonitis D010538 38 associated lipids
Lymphoma D008223 18 associated lipids
Alzheimer Disease D000544 76 associated lipids
Dentin, Secondary D003809 2 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Leukemia D007938 74 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Ma MK et al. Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrity. 2011 PLoS Genet. pmid:21811414
Deutschbauer A et al. Evidence-based annotation of gene function in Shewanella oneidensis MR-1 using genome-wide fitness profiling across 121 conditions. 2011 PLoS Genet. pmid:22125499
Hancock AM et al. Adaptations to climate-mediated selective pressures in humans. 2011 PLoS Genet. pmid:21533023
Adato A et al. Fruit-surface flavonoid accumulation in tomato is controlled by a SlMYB12-regulated transcriptional network. 2009 PLoS Genet. pmid:20019811
Guillemette B et al. H3 lysine 4 is acetylated at active gene promoters and is regulated by H3 lysine 4 methylation. 2011 PLoS Genet. pmid:21483810
Tie J et al. MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor. 2010 PLoS Genet. pmid:20300657
Solinger JA et al. The Caenorhabditis elegans Elongator complex regulates neuronal alpha-tubulin acetylation. 2010 PLoS Genet. pmid:20107598
Caulfield MJ et al. SLC2A9 is a high-capacity urate transporter in humans. 2008 PLoS Med. pmid:18842065
Relton CL and Davey Smith G Epigenetic epidemiology of common complex disease: prospects for prediction, prevention, and treatment. 2010 PLoS Med. pmid:21048988
Lüscher C and Ungless MA The mechanistic classification of addictive drugs. 2006 PLoS Med. pmid:17105338
Sprong H et al. Aberrant receptor-mediated endocytosis of Schistosoma mansoni glycoproteins on host lipoproteins. 2006 PLoS Med. pmid:16942390
Saric J et al. Metabolic profiling of an Echinostoma caproni infection in the mouse for biomarker discovery. 2008 PLoS Negl Trop Dis pmid:18596973
Sharling L et al. A screening pipeline for antiparasitic agents targeting cryptosporidium inosine monophosphate dehydrogenase. 2010 PLoS Negl Trop Dis pmid:20706578
Yang C et al. A constructed alkaline consortium and its dynamics in treating alkaline black liquor with very high pollution load. 2008 PLoS ONE pmid:19020664
Camarasa C et al. Phenotypic landscape of Saccharomyces cerevisiae during wine fermentation: evidence for origin-dependent metabolic traits. 2011 PLoS ONE pmid:21949874
Kittelmann S et al. A proposed taxonomy of anaerobic fungi (class neocallimastigomycetes) suitable for large-scale sequence-based community structure analysis. 2012 PLoS ONE pmid:22615827
McLean JS et al. Identifying low pH active and lactate-utilizing taxa within oral microbiome communities from healthy children using stable isotope probing techniques. 2012 PLoS ONE pmid:22403637
Tun HW et al. Pathway signature and cellular differentiation in clear cell renal cell carcinoma. 2010 PLoS ONE pmid:20502531
Osterstock G et al. Ghrelin stimulation of growth hormone-releasing hormone neurons is direct in the arcuate nucleus. 2010 PLoS ONE pmid:20161791
Dahl JA et al. Histone H3 lysine 27 methylation asymmetry on developmentally-regulated promoters distinguish the first two lineages in mouse preimplantation embryos. 2010 PLoS ONE pmid:20161773
Terova G et al. Effects of Sodium Butyrate Treatment on Histone Modifications and the Expression of Genes Related to Epigenetic Regulatory Mechanisms and Immune Response in European Sea Bass (Dicentrarchus Labrax) Fed a Plant-Based Diet. 2016 PLoS ONE pmid:27471849
Jawed K et al. Engineered Production of Short Chain Fatty Acid in Escherichia coli Using Fatty Acid Synthesis Pathway. 2016 PLoS ONE pmid:27466817
Mazuet C et al. Characterization of botulinum neurotoxin type A neutralizing monoclonal antibodies and influence of their half-lives on therapeutic activity. 2010 PLoS ONE pmid:20865035
Wu CY et al. PI3Ks maintain the structural integrity of T-tubules in cardiac myocytes. 2011 PLoS ONE pmid:21912691
Su J et al. Oxamflatin significantly improves nuclear reprogramming, blastocyst quality, and in vitro development of bovine SCNT embryos. 2011 PLoS ONE pmid:21912607
Astakhova L et al. Short Chain Fatty Acids (SCFA) Reprogram Gene Expression in Human Malignant Epithelial and Lymphoid Cells. 2016 PLoS ONE pmid:27441625
Gómez-Hurtado I et al. Gut microbiota dysbiosis is associated with inflammation and bacterial translocation in mice with CCl4-induced fibrosis. 2011 PLoS ONE pmid:21829583
Bhoopathi P et al. SPARC overexpression inhibits cell proliferation in neuroblastoma and is partly mediated by tumor suppressor protein PTEN and AKT. 2012 PLoS ONE pmid:22567126
Harris DM et al. Transformation of human mesenchymal cells and skin fibroblasts into hematopoietic cells. 2011 PLoS ONE pmid:21731684
Chandra V et al. Islet-like cell aggregates generated from human adipose tissue derived stem cells ameliorate experimental diabetes in mice. 2011 PLoS ONE pmid:21687731
Brown CT et al. Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes. 2011 PLoS ONE pmid:22043294
Kauh J et al. c-FLIP degradation mediates sensitization of pancreatic cancer cells to TRAIL-induced apoptosis by the histone deacetylase inhibitor LBH589. 2010 PLoS ONE pmid:20442774
Jalanka-Tuovinen J et al. Intestinal microbiota in healthy adults: temporal analysis reveals individual and common core and relation to intestinal symptoms. 2011 PLoS ONE pmid:21829582
Rao L et al. Solution behavior and activity of a halophilic esterase under high salt concentration. 2009 PLoS ONE pmid:19759821
VerMilyea MD et al. Transcription-independent heritability of induced histone modifications in the mouse preimplantation embryo. 2009 PLoS ONE pmid:19564914
Williams BL et al. Impaired carbohydrate digestion and transport and mucosal dysbiosis in the intestines of children with autism and gastrointestinal disturbances. 2011 PLoS ONE pmid:21949732
Dayal S et al. High resolution analysis of the chromatin landscape of the IgE switch region in human B cells. 2011 PLoS ONE pmid:21949728
Eloe EA et al. Going deeper: metagenome of a hadopelagic microbial community. 2011 PLoS ONE pmid:21629664
Demontis GC et al. Functional and molecular characterization of rod-like cells from retinal stem cells derived from the adult ciliary epithelium. 2012 PLoS ONE pmid:22432014
Brim H et al. SLC5A8 gene, a transporter of butyrate: a gut flora metabolite, is frequently methylated in African American colon adenomas. 2011 PLoS ONE pmid:21687703
Chatterjee T et al. Interaction of virstatin with human serum albumin: spectroscopic analysis and molecular modeling. 2012 PLoS ONE pmid:22649528
Russo I et al. Butyrate attenuates lipopolysaccharide-induced inflammation in intestinal cells and Crohn's mucosa through modulation of antioxidant defense machinery. 2012 PLoS ONE pmid:22412931
Shin DH et al. Arrest defective-1 controls tumor cell behavior by acetylating myosin light chain kinase. 2009 PLoS ONE pmid:19826488
Zonari A et al. Endothelial differentiation of human stem cells seeded onto electrospun polyhydroxybutyrate/polyhydroxybutyrate-co-hydroxyvalerate fiber mesh. 2012 PLoS ONE pmid:22523594
Quave CL et al. Ellagic acid derivatives from Rubus ulmifolius inhibit Staphylococcus aureus biofilm formation and improve response to antibiotics. 2012 PLoS ONE pmid:22242149
Miles J et al. Intergenic transcription, cell-cycle and the developmentally regulated epigenetic profile of the human beta-globin locus. 2007 PLoS ONE pmid:17637845
Biagi E et al. Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians. 2010 PLoS ONE pmid:20498852
Bai G et al. Comparison of storage conditions for human vaginal microbiome studies. 2012 PLoS ONE pmid:22655031
Salzler HR et al. Loss of the histone pre-mRNA processing factor stem-loop binding protein in Drosophila causes genomic instability and impaired cellular proliferation. 2009 PLoS ONE pmid:19997601
Kil DY et al. Gene expression profiles of colonic mucosa in healthy young adult and senior dogs. 2010 PLoS ONE pmid:20877568
Lee HS et al. Associations among organochlorine pesticides, Methanobacteriales, and obesity in Korean women. 2011 PLoS ONE pmid:22114690
Forster S et al. Characterization of rhodamine-123 as a tracer dye for use in in vitro drug transport assays. 2012 PLoS ONE pmid:22470447
Pilka ES et al. Structural basis for substrate specificity in human monomeric carbonyl reductases. 2009 PLoS ONE pmid:19841672
Å kalamera D et al. A high-throughput platform for lentiviral overexpression screening of the human ORFeome. 2011 PLoS ONE pmid:21629697
Bishay P et al. R-flurbiprofen reduces neuropathic pain in rodents by restoring endogenous cannabinoids. 2010 PLoS ONE pmid:20498712
Le Bras A et al. VE-statin/egfl7 expression in endothelial cells is regulated by a distal enhancer and a proximal promoter under the direct control of Erg and GATA-2. 2010 PLoS ONE pmid:20808444
Vathsala PG et al. Curcumin-arteether combination therapy of Plasmodium berghei-infected mice prevents recrudescence through immunomodulation. 2012 PLoS ONE pmid:22276114
Lazarini F et al. Cellular and behavioral effects of cranial irradiation of the subventricular zone in adult mice. 2009 PLoS ONE pmid:19753118
Sannasiddappa TH et al. The influence of Staphylococcus aureus on gut microbial ecology in an in vitro continuous culture human colonic model system. 2011 PLoS ONE pmid:21858036
Wohlfart S et al. Efficient chemotherapy of rat glioblastoma using doxorubicin-loaded PLGA nanoparticles with different stabilizers. 2011 PLoS ONE pmid:21573151
Sellitto M et al. Proof of concept of microbiome-metabolome analysis and delayed gluten exposure on celiac disease autoimmunity in genetically at-risk infants. 2012 PLoS ONE pmid:22432018
Hendriksen H et al. Environmental enrichment induces behavioral recovery and enhanced hippocampal cell proliferation in an antidepressant-resistant animal model for PTSD. 2010 PLoS ONE pmid:20700523
Cook BL et al. Study of a synthetic human olfactory receptor 17-4: expression and purification from an inducible mammalian cell line. 2008 PLoS ONE pmid:18682799
Liang J et al. Genome-wide survey and expression profiling of CCCH-zinc finger family reveals a functional module in macrophage activation. 2008 PLoS ONE pmid:18682727
Waite DW et al. Gut microbiome of the critically endangered New Zealand parrot, the kakapo (Strigops habroptilus). 2012 PLoS ONE pmid:22530070
Amoêdo ND et al. Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors. 2011 PLoS ONE pmid:21789245
Dash PK et al. Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats. 2010 PLoS ONE pmid:20614021
Tang J et al. Propofol inhibits the activation of p38 through up-regulating the expression of annexin A1 to exert its anti-inflammation effect. 2011 PLoS ONE pmid:22164217
Rankovic V et al. Modulation of calcium-dependent inactivation of L-type Ca2+ channels via β-adrenergic signaling in thalamocortical relay neurons. 2011 PLoS ONE pmid:22164209
Miletta MC et al. Butyrate increases intracellular calcium levels and enhances growth hormone release from rat anterior pituitary cells via the G-protein-coupled receptors GPR41 and 43. 2014 PLoS ONE pmid:25310566
White MK et al. Rad51 activates polyomavirus JC early transcription. 2014 PLoS ONE pmid:25310191
Takayama H et al. High-level expression, single-step immunoaffinity purification and characterization of human tetraspanin membrane protein CD81. 2008 PLoS ONE pmid:18523555
May JS et al. An in vitro system for studying murid herpesvirus-4 latency and reactivation. 2010 PLoS ONE pmid:20552028
Zhang X et al. Androgen receptor variants occur frequently in castration resistant prostate cancer metastases. 2011 PLoS ONE pmid:22114732
Si J et al. Activation of NF-κB in basolateral amygdala is required for memory reconsolidation in auditory fear conditioning. 2012 PLoS ONE pmid:22957038
Jakubík J et al. Subtype differences in pre-coupling of muscarinic acetylcholine receptors. 2011 PLoS ONE pmid:22110745
Yan H and Ajuwon KM Butyrate modifies intestinal barrier function in IPEC-J2 cells through a selective upregulation of tight junction proteins and activation of the Akt signaling pathway. 2017 PLoS ONE pmid:28654658
Tang X et al. Systems biology of the qa gene cluster in Neurospora crassa. 2011 PLoS ONE pmid:21695121
Chen YJ et al. Epstein-Barr virus (EBV) Rta-mediated EBV and Kaposi's sarcoma-associated herpesvirus lytic reactivations in 293 cells. 2011 PLoS ONE pmid:21423768
Musch T et al. Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors. 2010 PLoS ONE pmid:20502711
De Weirdt R et al. Glycerol supplementation enhances L. reuteri's protective effect against S. Typhimurium colonization in a 3-D model of colonic epithelium. 2012 PLoS ONE pmid:22693569
Zhang J et al. Stereoselective regulations of P-glycoprotein by ginsenoside Rh2 epimers and the potential mechanisms from the view of pharmacokinetics. 2012 PLoS ONE pmid:22530069
Liu K et al. Characterization of the autocrine/paracrine function of vitamin D in human gingival fibroblasts and periodontal ligament cells. 2012 PLoS ONE pmid:22761920
Yang CH et al. Role of IKK/NF-κB signaling in extinction of conditioned place aversion memory in rats. 2012 PLoS ONE pmid:22761874
Danzeisen JL et al. Modulations of the chicken cecal microbiome and metagenome in response to anticoccidial and growth promoter treatment. 2011 PLoS ONE pmid:22114729
Lin Y et al. Use of sodium butyrate as an alternative to dietary fiber: effects on the embryonic development and anti-oxidative capacity of rats. 2014 PLoS ONE pmid:24852604
Bordonaro M et al. A switch from canonical to noncanonical Wnt signaling mediates drug resistance in colon cancer cells. 2011 PLoS ONE pmid:22073312
Utsugi C et al. Hard-diet feeding recovers neurogenesis in the subventricular zone and olfactory functions of mice impaired by soft-diet feeding. 2014 PLoS ONE pmid:24817277
Yu C et al. RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice. 2011 PLoS ONE pmid:22073188
Kamal MZ et al. Role of active site rigidity in activity: MD simulation and fluorescence study on a lipase mutant. 2012 PLoS ONE pmid:22514720
Cardenal-Muñoz E and Ramos-Morales F Analysis of the expression, secretion and translocation of the Salmonella enterica type III secretion system effector SteA. 2011 PLoS ONE pmid:22046414
Zhang Z et al. Efficient generation of fully reprogrammed human iPS cells via polycistronic retroviral vector and a new cocktail of chemical compounds. 2011 PLoS ONE pmid:22046312
Huang J et al. SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts. 2008 PLoS ONE pmid:18320031
Martin B et al. Gonadal transcriptome alterations in response to dietary energy intake: sensing the reproductive environment. 2009 PLoS ONE pmid:19127293
Han B et al. Suppression of AP1 transcription factor function in keratinocyte suppresses differentiation. 2012 PLoS ONE pmid:22649503
Xu Z et al. Evidence for OTUD-6B participation in B lymphocytes cell cycle after cytokine stimulation. 2011 PLoS ONE pmid:21267069
Nichols LA et al. Rapamycin blocks production of KSHV/HHV8: insights into the anti-tumor activity of an immunosuppressant drug. 2011 PLoS ONE pmid:21264294
Neis EP et al. Effects of Liver Resection on Hepatic Short-Chain Fatty Acid Metabolism in Humans. 2016 PLoS ONE pmid:27835668
Bellgard MI et al. Genome sequence of the pathogenic intestinal spirochete brachyspira hyodysenteriae reveals adaptations to its lifestyle in the porcine large intestine. 2009 PLoS ONE pmid:19262690
Boichuk S et al. Functional connection between Rad51 and PML in homology-directed repair. 2011 PLoS ONE pmid:21998700