butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Vicente F et al. | Subclinical ketosis on dairy cows in transition period in farms with contrasting butyric acid contents in silages. | 2014 | ScientificWorldJournal | pmid:25525616 |
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Ozadali K et al. | Synthesis and antimycobacterial activities of some new thiazolylhydrazone derivatives. | 2014 | Bioorg. Med. Chem. Lett. | pmid:24631185 |
Shen H et al. | BMI1 reprogrammes histone acetylation and enhances c-fos pathway via directly binding to Zmym3 in malignant myeloid progression. | 2014 | J. Cell. Mol. Med. | pmid:24571310 |
Karki P et al. | Yin Yang 1 is a repressor of glutamate transporter EAAT2, and it mediates manganese-induced decrease of EAAT2 expression in astrocytes. | 2014 | Mol. Cell. Biol. | pmid:24469401 |
Pérez-Carro R et al. | Functional analysis and in vitro correction of splicing FAH mutations causing tyrosinemia type I. | 2014 | Clin. Genet. | pmid:23895425 |
Xu G et al. | SAHA regulates histone acetylation, Butyrylation, and protein expression in neuroblastoma. | 2014 | J. Proteome Res. | pmid:25160476 |
Khan S and Jena G | Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-β1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats. | 2014 | Food Chem. Toxicol. | pmid:25158305 |
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Chou AH et al. | Polyglutamine-expanded ataxin-3 impairs long-term depression in Purkinje neurons of SCA3 transgenic mouse by inhibiting HAT and impairing histone acetylation. | 2014 | Brain Res. | pmid:25139423 |
Reindl A et al. | Enumeration of clostridia in goat milk using an optimized membrane filtration technique. | 2014 | J. Dairy Sci. | pmid:25129496 |
Kanski R et al. | Histone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament network. | 2014 | J. Cell. Sci. | pmid:25128567 |
Lee JM et al. | Direct hydrogenation of biomass-derived butyric acid to n-butanol over a ruthenium-tin bimetallic catalyst. | 2014 | ChemSusChem | pmid:25123894 |
Lopez CA et al. | Collateral damage: microbiota-derived metabolites and immune function in the antibiotic era. | 2014 | Cell Host Microbe | pmid:25121745 |
Cho HJ and Song MJ | A gammaherpesvirus establishes persistent infection in neuroblastoma cells. | 2014 | Mol. Cells | pmid:25092213 |
Li S et al. | High-grain diets suppress ruminal tissue abundance of angiopoietin-like protein 4 in cattle. | 2014 | J. Anim. Sci. | pmid:25085388 |
Tiwari P and Gupta KP | Modulation of miR-203 and its regulators as a function of time during the development of 7, 12 dimethylbenz [a] anthracene induced mouse skin tumors in presence or absence of the antitumor agents. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24792773 |
Pasvolsky R et al. | Butyric acid released during milk lipolysis triggers biofilm formation of Bacillus species. | 2014 | Int. J. Food Microbiol. | pmid:24801271 |
Maggio A et al. | Daily sodium butyrate enema for the prevention of radiation proctitis in prostate cancer patients undergoing radical radiation therapy: results of a multicenter randomized placebo-controlled dose-finding phase 2 study. | 2014 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:24803033 |
Ellis JT et al. | Microbial bioproducts from cheese whey through fermentation with wastewater sludge Clostridium isolates. | 2014 | Can. J. Microbiol. | pmid:24898684 |
Ochiai K and Kurita-Ochiai T | [Alternative effects of a metabolic by-product, butyric acid, produced by oral anaerobes]. | 2014 | Nippon Yakurigaku Zasshi | pmid:25109521 |
Liu W et al. | Effects of dietary microencapsulated sodium butyrate on growth, intestinal mucosal morphology, immune response and adhesive bacteria in juvenile common carp (Cyprinus carpio) pre-fed with or without oxidised oil. | 2014 | Br. J. Nutr. | pmid:24774835 |
Ladirat SE et al. | Exploring the effects of galacto-oligosaccharides on the gut microbiota of healthy adults receiving amoxicillin treatment. | 2014 | Br. J. Nutr. | pmid:24925303 |
Jang YS et al. | Metabolic engineering of Clostridium acetobutylicum for butyric acid production with high butyric acid selectivity. | 2014 | Metab. Eng. | pmid:24704310 |
Syngiridis K et al. | Favouring butyrate production for a new generation biofuel by acidogenic glucose fermentation using cells immobilised on γ-alumina. | 2014 | Bioresour. Technol. | pmid:24690582 |
Sarkar A et al. | Hippocampal HDAC4 contributes to postnatal fluoxetine-evoked depression-like behavior. | 2014 | Neuropsychopharmacology | pmid:24663010 |
Csikó G et al. | Effects of dietary sodium butyrate on hepatic biotransformation and pharmacokinetics of erythromycin in chickens. | 2014 | J. Vet. Pharmacol. Ther. | pmid:24628435 |
Han A et al. | Possible additional antidepressant-like mechanism of sodium butyrate: targeting the hippocampus. | 2014 | Neuropharmacology | pmid:24607816 |
Park HG et al. | Repeated treatment with electroconvulsive seizures induces HDAC2 expression and down-regulation of NMDA receptor-related genes through histone deacetylation in the rat frontal cortex. | 2014 | Int. J. Neuropsychopharmacol. | pmid:24606669 |
Aguilar EC et al. | Butyrate impairs atherogenesis by reducing plaque inflammation and vulnerability and decreasing NFκB activation. | 2014 | Nutr Metab Cardiovasc Dis | pmid:24602606 |
Sabra W et al. | Improved n-butanol production by a non-acetone producing Clostridium pasteurianum DSMZ 525 in mixed substrate fermentation. | 2014 | Appl. Microbiol. Biotechnol. | pmid:24584460 |
Blank M et al. | Basolateral amygdala activity is required for enhancement of memory consolidation produced by histone deacetylase inhibition in the hippocampus. | 2014 | Neurobiol Learn Mem | pmid:24583371 |
Possebom G et al. | Esterification of fatty acids by Penicillium crustosum lipase in a membrane reactor. | 2014 | J. Sci. Food Agric. | pmid:24578290 |
Zhang Z et al. | Sodium butyrate facilitates reprogramming by derepressing OCT4 transactivity at the promoter of embryonic stem cell-specific miR-302/367 cluster. | 2014 | Cell Reprogram | pmid:24568633 |
Lee SM et al. | Digital mRNA profiling of N-glycosylation gene expression in recombinant Chinese hamster ovary cells treated with sodium butyrate. | 2014 | J. Biotechnol. | pmid:24333461 |
Dostal A et al. | Iron supplementation promotes gut microbiota metabolic activity but not colitis markers in human gut microbiota-associated rats. | 2014 | Br. J. Nutr. | pmid:24555487 |
Khan S and Jena GB | Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: study in juvenile diabetic rat. | 2014 | Chem. Biol. Interact. | pmid:24530320 |
Ferreira AC et al. | Histone deacetylase inhibitor prevents cell growth in Burkitt's lymphoma by regulating PI3K/Akt pathways and leads to upregulation of miR-143, miR-145, and miR-101. | 2014 | Ann. Hematol. | pmid:24577510 |
Dengler F et al. | Bicarbonate-dependent transport of acetate and butyrate across the basolateral membrane of sheep rumen epithelium. | 2014 | Acta Physiol (Oxf) | pmid:23927569 |
Meehan CJ and Beiko RG | A phylogenomic view of ecological specialization in the Lachnospiraceae, a family of digestive tract-associated bacteria. | 2014 | Genome Biol Evol | pmid:24625961 |
Yan SF et al. | HDAC inhibitor sodium butyrate augments the MEF2C enhancement of Nampt expression under hypoxia. | 2014 | Curr. Pharm. Des. | pmid:23888946 |
Pan Y et al. | Potential usefulness of baculovirus-mediated sodium-iodide symporter reporter gene as non-invasively gene therapy monitoring in liver cancer cells: an in vitro evaluation. | 2014 | Technol. Cancer Res. Treat. | pmid:23919394 |
Drees J et al. | Butyrate stimulates the early process of the osteogenic differentiation but inhibits the biomineralization in dental follicle cells (DFCs). | 2014 | Odontology | pmid:23836050 |